531 results about "Flavoring Agents" patented technology

The present disclosure provides a method for treating pain or inflammation in a non-human animal in need thereof. The method comprises administering to a non-human animal a pharmaceutical composition comprising a therapeutically effective amount of grapiprant. Also provided herein are pharmaceutical compositions for treating pain or inflammation in a non-human animal in need thereof. The pharmaceutical compositions comprise a therapeutically effective amount of grapiprant and an excipient, including flavorants.

The disclosure provides liquid compositions configured for oral use, the liquid composition comprising water in an amount of about 40% by weight or higher, based on total weight of the composition, a flavoring agent or an active ingredient or both a flavoring agent and an active ingredient, and one or more additional components selected from the group consisting of sweeteners, humectants, and alkali metal salts, wherein the composition has a water activity (Aw) of about 0.85 or lower. The liquid compositions are generally suitable for spraying into the oral cavity.

The invention belongs to the technical field of medicines, and particularly relates to macloxvir direct granules and a preparation method thereof. The taste is improved by adding the flavoring agent and a multi-layer coating technology, and the effect of direct swallowing is realized; by controlling the particle size of the raw materials and the variety and dosage of the auxiliary materials, the obtained macloxvir direct-taking granules are excellent in dissolution performance; and the stabilizer is added, so that the obtained macloxvir direct-taking granules are excellent in stability. In addition to providing a product which can be divided into doses and can be directly swallowed, the macloxvir directly-taken granules disclosed by the invention are stable and controllable in prescription process, excellent in dissolution performance, relatively good in mouth feel, taste masking effect and stability, suitable for large-scale production and good in market prospect.

The present disclosure provides a method for treating pain or inflammation in a non-human animal in need thereof. The method comprises administering to a non-human animal a pharmaceutical composition comprising a therapeutically effective amount of grapiprant. Also provided herein are pharmaceutical compositions for treating pain or inflammation in a non-human animal in need thereof. The pharmaceutical compositions comprise a therapeutically effective amount of grapiprant and an excipient, including flavorants.

The invention relates to the technical field of pet food, in particular to flavoring agent powder for pet dogs and a preparation method of the flavoring agent powder. Comprising the following raw materials: 40 parts of beef liver, 10 parts of hairtail, 7-40 parts of ricefield eel, 1 part of protease, 0.5-1 part of lipase, 0.5-1 part of flavor enzyme, 5-10 parts of saccharides, 10 parts of fish oil, 5-10 parts of maltodextrin, 0.5-1 part of sodium hydroxide, 5 parts of phosphoric acid, 3 parts of amino acid, 2 parts of thiamine, 1 part of yeast extract and 0.5-1 part of lactoferrin. The dog feed can increase the appetite of dogs from the sense of smell, maintain the health balance of intestinal flora of dogs and improve the micro-ecological environment of intestinal tracts.

The application provides a preparation method of seafood flavoring agent and shrimp paste, and relates to the technical field of food flavoring agents. The slurry of shrimp offal is subjected to enzymolysis by using a combination of neutral protease, flavor protease, nuclease and lipase, and then subjected to Maillard reaction, so that the seafood flavoring agent with high freshness, low bitterness and good flavor is obtained, and the seafood flavoring agent can be used for preparing shrimp paste.

The invention provides a dexketoprofen trometamol oral solution and a preparation method thereof. According to the dexketoprofen trometamol oral solution, polyethylene glycol 400 and hydroxypropyl methylcellulose are used as stabilizing agents, methylparaben and propyl hydroxybenzoate are used as bacteriostatic agents, sucralose and ammonium glycyrrhizinate are used as sweetening agents, essence is used as a flavoring agent, and the pH value of the solution is controlled to be 6.2-6.8 through a pH value regulator. The increase of the impurity A, the impurity B, the impurity C, the impurity E and the total impurity is obviously reduced, so that the product stability is obviously improved.

The invention relates to a rebamipide TBPH ion pair compound freeze-dried flash release tablet and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. Comprising the following components in parts by weight: 80-90 parts of a rebamipide TBPH ion pair compound, 60-100 parts of a proppant, 8-20 parts of a stabilizer, 8-15 parts of an acidulant, 1-5 parts of a sweetening agent and 3-8 parts of a flavoring agent. The rebamipide TBPH ion pair compound has the advantages that in order to improve the solubility and bioavailability of rebamipide, the rebamipide is firstly prepared into the rebamipide TBPH ion pair compound, so that the hydrophilicity and lipophilicity of the rebamipide TBPH ion pair compound are effectively improved, the solubility of the rebamipide TBPH ion pair compound in water or lipid can be remarkably improved, and then quick release and dissolution are realized through a freeze-drying technology; the tablet can be rapidly disintegrated and dissolved in a short time, is good in molding, free of cracking and collapse phenomena, free of water during taking, convenient to take, instant to dissolve in the mouth, good in taste, free of grit feeling, free of peculiar smell, convenient to take by a patient, rapid in effect taking, capable of reducing waiting time after taking, and capable of improving the bioavailability of the tablet.

The invention provides a nicotine-containing gel and a preparation method thereof. The nicotine-containing gel comprises the following components: a nicotine microcapsule, a penetrant, a gel matrix, a flavoring agent and water. The gel has excellent biocompatibility and slow release performance through combination of the nicotine microcapsules and the gel matrix, the skin permeability of nicotine can be improved by adding the penetrant, and the gel has the advantages of freshening the oral cavity and keeping fragrance for a long time by adding the flavoring agent. Therefore, a new consumption choice can be provided for smoking cessation groups and patients needing nicotine medicine.

The invention belongs to the field of daily chemicals, and particularly relates to a body cleaning composition containing folium artemisiae argyi extract and a preparation method of the body cleaning composition. 14%-20% of a surfactant; 0.5-5% of a skin conditioner; 0.01%-0.1% of a metal chelating agent; 0.01%-1.2% of a preservative; 0.01%-1% of a pH regulator; 1 to 1.5 percent of flavoring agent; 0.01%-1% of a viscosity modifier; and the balance of deionized water. The plant functional composition comprises a folium artemisiae argyi extract and a rosa canina fruit extract. The folium artemisiae argyi extract and the rosa canina fruit extract in the composition can achieve a synergistic effect, free radicals can be effectively removed, release of cell factors and inflammatory mediators can be inhibited, and the composition has anti-inflammatory and soothing effects, can relieve uncomfortable symptoms such as skin redness and itching and has a certain whitening effect.

The invention relates to the field of food materials, and particularly discloses a gamma-aminobutyric acid and hydrolyzed egg yolk powder composite beverage capable of promoting sleep and inhibiting bone age and a preparation method of the gamma-aminobutyric acid and hydrolyzed egg yolk powder composite beverage. A gamma-aminobutyric acid and hydrolyzed egg yolk powder composite beverage capable of promoting sleep and inhibiting bone age comprises the following raw materials in percentage: 3-5% of xylitol, 3-5% of fructo-oligosaccharide, 2-4% of gamma-aminobutyric acid, 3-9% of antioxidant composite concentrated juice, 0.16-1% of purple carrot juice beverage thick slurry, 0.1-0.19% of calcium aspartate, 0.02-0.05% of casein hydrolyzed peptide, 0.02-0.05% of hydrolyzed egg yolk powder, 0.02-0.05% of casein phosphopeptide and the balance of water. The formula comprises the following components in percentage by weight: 0.006 to 0.01 percent of zinc gluconate, 0.0005 to 0.00085 percent of zinc-rich edible yeast powder, 0.0005 to 0.00085 percent of tea theanine, 0.0005 to 0.00085 percent of N-acetylneuraminic acid, 0.0018 to 0.09 percent of a traditional Chinese medicine composition, 0.005 to 0.01 percent of L-calcium lactate, 0.0005 to 0.01 percent of collagen peptide, 0.1 to 0.3 percent of xanthan gum, 0.0005 to 0.00085 percent of melissa officinalis, 0.2 to 0.98 percent of a compound flavoring agent and the balance of purified water. Through the synergistic effect of all the components, the sleep quality is effectively improved, overactivity of bone cells is inhibited, and the bone age development is delayed.

The disclosure provides compositions configured for oral use, such as pouched products. Example pouched products configured for oral use can include a composition enclosed within a water-permeable pouch, the composition including a particulate filler component; one or more sweeteners; and a releasable component selected from the group consisting of flavoring agents, active ingredients, and combinations thereof; wherein the composition is substantially free of sucralose.

The present invention provides a young pigeon seasoning marinating material formula and a young pigeon manufacturing method, and relates to the technical field of food processing, and the young pigeon seasoning marinating material formula comprises 30-35 parts of licorice roots, 90-110 parts of siraitia grosvenorii, 10-14 parts of star anise, 18-22 parts of cassia barks, 6-10 parts of cloves, 14-18 parts of fennel, 18-22 parts of kaempferia galanga, 18-22 parts of amomum tsao-ko, 10-14 parts of dried orange peel, 18-22 parts of Chinese prickly ash, 2-6 parts of bay leaves, 10-30 parts of garlic bulbs, 10-30 parts of galangal, 45-55 parts of edible salt and young pigeons with net weight of 275-350g. Soy sauce, chicken essence, monosodium glutamate and sugar are canceled as core seasoning components, so that the natural sweetness of liquorice and momordica grosvenori can replace an artificial flavoring agent, and the composite fragrance of spices such as anise and cinnamon can cover the defect of single salty and delicious taste of a traditional marinating material; chinese herbal medicine composite fragrance needed by the braised squab can be reproduced, and the stewed squab is mellow and sweet in aftertaste and red and bright in natural color.

The invention relates to the technical field of functional beverages, in particular to a composite polypeptide solid beverage with a uric acid reducing function and a preparation method of the composite polypeptide solid beverage. The composite polypeptide solid beverage with the uric acid reducing function is prepared from the following raw materials in percentage by weight: 15-25% of plukenetia volubilis extract, 30-40% of lysimachia christinae hance-plantain herb composite extract, 8-12% of oyster peptide powder, 5-8% of earthworm protein peptide freeze-dried powder and 3-5% of a flavoring agent. Wherein the ratio of a lysimachia christinae hance extract to a plantain herb extract in the lysimachia christinae hance-plantain herb composite extract is 3: The flavoring agent is erythritol and / or stevioside, xanthine oxidase is inhibited by using flavonoid substances, GLUT9 expression is synergistically down-regulated by using bispyribaloside, PRPP synthetase activity is regulated by using zinc-rich peptide, uric acid micro-crystals are dissolved by using earthworm protein peptide, a multi-target action network of flavonoid-glycoside-bioactive peptide is achieved, and the effect of improving the bioavailability of the flavonoid-glycoside-bioactive peptide is achieved. And triple mechanisms of excretion promotion, generation inhibition and kidney protection are realized.

The disclosure provides products configured for oral use, the products including a mixture of a particulate filler, water, one or more organic acids, and one or more flavoring agents, the product having a pH value of less than about 7.0. The products exhibit greater stability over time with respect to whiteness and / or flavor component concentration than products which do not contain one or more organic acids.

The invention relates to the technical field of toothpaste preparation, and particularly discloses a Chinese herbal medicine toothpaste formula and a preparation method thereof, the Chinese herbal medicine toothpaste formula comprises the following raw materials by weight: 17-18 parts of a functional component, 2.4-2.8 parts of a slow release synergist, 20-22 parts of a friction agent, 28-32 parts of a humectant, 2.6-3.4 parts of a surfactant, 0.16-0.18 part of a preservative, 1.8-2 parts of a thickener, 1.4-1.6 parts of essence, 5.8-6.2 parts of a flavoring agent and 16-18 parts of deionized water; taxillus sutchuenensis, herba cepbalanoplosis segeti, plantain herb, herba pyrolae and fructus forsythiae are used as core materials of functional components, gelatin and modified sodium alginate are used as wall materials, the functional components are prepared, and a slow-release synergist containing anthocyanin, bromelain and rhamnolipid is added, so that the effects of removing stains and whitening skin are achieved; moreover, release of quercetin, quercitrin and other components in the traditional Chinese medicine extract is promoted, and the anti-inflammatory, bleeding-stopping, halitosis-removing, stain-removing and whitening effects of the toothpaste are improved.

The preparation method comprises the following steps: directionally enriching glycyrrhizic acid and liquiritin through a four-step process of temperature-controlled countercurrent extraction, acid precipitation and enrichment, membrane filtration and resin separation, and synchronously removing polysaccharides, pectin and bitter substance glycyrrhetinic acid residues. Compared with a traditional method, the method has the triple advantages that (1) the sweetness enhancing function is achieved, and glycyrrhizic acid and liquiritin cooperate to achieve 2-10 times of wine sweetness adjustment; 2) the stability is prominent, and the turbidity is only increased by 2NTU (25NTU in the traditional process) through 30-day acceleration test; 3) the sensory quality is optimized, and the sensory score of the blended wine body reaches 92 (the medicinal aroma and the wine aroma are harmonious and precipitate-free).

The application provides probiotic oral burst balls and a preparation process, and belongs to the technical field of probiotic embedding. The probiotic oral burst balls comprise core materials and wall materials. The core materials comprise probiotic raw materials, a flavoring agent, mannose, xylitol, mannose oligosaccharide, glycine, vitamin E and a solvent 1, and the solvent 1 is an oily solvent. The wall materials comprise trehalose, gelatin, cyclic dextrin and a solvent 2, and the solvent 2 is an oily solvent. The probiotic oral burst balls prepared by the preparation process have the characteristics of temperature resistance, acid resistance and storage resistance.

Disclosed is a pharmaceutical composition comprising loratadine and one or more pharmaceutically acceptable excipients, fruit powders, gelling agent and other additives The additives may include buffering agenting agents, binders, stabilizing agents, solubilizing agents, colorants, sweetening agents, preservatives, coating agents, flavoring agents and diluents. The present disclosure provides for loratadine, where the buccal absorption is faster as well as the active ingredients in gum can be absorbed directly through the mucous membranes in the mouth, reducing the drawbacks of the conventional gummies which encounters the challenges of very high thermal stress of the cooking process especially where the active ingredients subject to significant chemical and / or physical degradation during the manufacturing process. The present disclosure further provides a method (100) of formulating the gummy dosage pharmaceutical composition for loratadine.

The present invention relates to a novel smoking article including a flavoring agent, and more particularly, to a smoking article including a flavoring agent including, in a basic skeleton thereof, a moiety derived from a sugar compound and a moiety derived from a flavor compound, which is a novel compound decomposed into a lactone compound, a sugar compound, and a flavor compound upon thermal decomposition.

The disclosure provides an oral composition adapted for oral use that includes sugarcane plant fiber in addition to one or more active ingredients, flavorants, or combinations thereof. The oral composition can be, for example, a pouched product wherein the oral composition is a particulate composition enclosed within a water-permeable pouch.

The invention discloses popping capsules containing soft glutinous gorgon fruits, and belongs to the technical field of popping capsule production, the popping capsules containing soft glutinous gorgon fruits comprise the following components in parts by weight: the balance of soft glutinous gorgon fruits, 5-9 parts of an inner solution and 5-9 parts of an outer solution, the inner solution comprises the following raw materials: 3-6 parts of sodium alginate, 0.1-0.3 part of a flavor enhancer, 0.1-0.5 part of xanthan gum, 0.2-0.4 part of konjac glucomannan, and the balance of drinking water; the sodium alginate is prepared from kelp, the external solution comprises the following raw materials: 2-4 parts of calcium lactate and the balance of warm water, and the calcium lactate is prepared from rice; according to the invention, the xanthan gum is arranged, the liquid viscosity can be obviously improved through the xanthan gum, a stable gel structure can be formed at low concentration, carboxyl and hydroxyl on a molecular chain of the xanthan gum are combined with water molecules through hydrogen bonds to form a three-dimensional network structure, so that the blasting bead is thickened through the characteristic, and the stability of the blasting bead is improved; and therefore, the phenomenon that the taste is influenced by excessive softening of the popping beads is avoided.

Liquid formulation including cevimeline hydrochloride and a combination of at least one sweetener and at least one flavoring agent to mask the bitter taste of cevimeline hydrochloride oral solutions. The liquid formulation may be administered to a patient to alleviate dry mouth symptoms associated with xerostomia and Sjogren's syndrome.

Compositions in the form of an oil-in-water emulsion composition include an oil phase that includes a flavorant; and a continuous aqueous phase that includes water, a preservative and a phospholipid emulsifying agent, and optionally an emulsifier adjuvant; wherein the phospholipid emulsifying agent includes a low content of primary ammonium functional groups.

The invention relates to the technical field of oral care compositions, in particular to an oral care composition and a preparation method and application thereof.The oral care composition comprises a first composition and a second composition, the first composition comprises an anti-sensitive agent, a cosolvent, a first thickening agent, a surfactant and a first auxiliary, and the second composition comprises an anti-sensitive agent, a cosolvent, a second thickening agent, a surfactant and a second auxiliary; the first composition comprises phthalimide peroxyhexanoic acid, a cosolvent, a first thickening agent, a first auxiliary agent and deionized water, the second composition comprises phthalimide peroxyhexanoic acid, a cosolvent, a second thickening agent, a second auxiliary agent and deionized water, at least one of the cosolvent, the first auxiliary agent and the second auxiliary agent contains a flavoring agent, and the first composition and the second composition are separately stored before use. The anti-sensitive agent is prevented from being in contact with the phthalimide peroxyhexanoic acid before use. According to the invention, the first composition and the second composition are respectively and independently stored, so that natural decomposition and activity attenuation of phthalimide peroxycaproic acid in the shelf life of the product are inhibited, and the product is ensured to retain high effective active oxygen content after being stored for a long time.

This invention provides a flavoring agent for enhancing the honey-sweet aroma of tobacco, comprising the following raw materials and their mass percentages: 0.2-0.3% 2,3-pentanedione, 0.45-0.55% phenylacetic acid, 0.45-0.55% phenethyl acetate, 0.25-0.4% phenylethanol, 0.45-0.6% methyl phenylacetate, 0.45-0.6% ethyl phenylacetate, 0.5-0.6% menthyl acetate, 0.15-0.25% geraniol, and the balance being propylene glycol. This invention belongs to the field of tobacco flavoring technology. By combining 2,3-pentanedione, phenylacetic acid, and phenethyl acetate in a specific mass ratio and conducting testing and evaluation, a flavoring agent suitable for enhancing the honey-sweet aroma of tobacco has been successfully developed. The composition is clearly defined, significantly improving the honey-sweet aroma of tobacco products, with a rich and long-lasting aroma, and good taste harmony.

The invention provides a fat-reducing nutritional composition containing a kelp extract and a preparation method of the fat-reducing nutritional composition, belongs to the technical field of foods, and relates to fermentation engineering and marine food manufacturing. The fat-reducing nutritional composition comprises the following components: a kelp extract, opuntia ficus-indica powder, an enhancer, a flavoring agent and a nutritional agent, wherein the enhancer is prepared from calcium beta-hydroxy-beta-methyl butyrate, catechin and betaine. The fat-reducing nutritional composition disclosed by the invention is scientific in compatibility of the components, can effectively regulate catabolism of fat, improve fat consumption, reduce fat accumulation, timely supplement nutrition, prevent muscle loss, synchronously improve the metabolic level and immunity of a body, and achieve the effects of health and fat reduction.

The method includes the steps of providing a plant protein substrate and fermenting the plant protein substrate with a starter culture containing *Lactobacillus johnsonii*. The invention also relates to plant-based products from such fermentation and *Lactobacillus johnsonii* strains suitable for use in the invention. The invention further relates to peptides that impart and / or enhance rich flavors, methods for preparing such peptides, compositions containing such peptides, and the use of such peptides as flavoring agents.

The invention provides manufacturing equipment for buccal products, and belongs to the technical field of buccal products, the manufacturing equipment is used for preparing buccal products containing active substances and / or flavoring agents, and the manufacturing equipment comprises a feeding unit used for providing a base material; the material applying unit is arranged at the downstream of the material supplying unit and is used for applying a filling agent comprising an active substance and / or a flavoring agent to form a filling layer laminated with the base material; the film covering unit is arranged at the downstream of the feeding unit and is used for covering a film to form a film covering layer which is laminated with the base material and the filling layer, so that the buccal product is obtained; wherein the material applying unit comprises at least one material applying module, and one material applying module can be selectively used for forming at least one filling layer of each buccal product; the film covering unit comprises at least one film covering module, and one film covering module can be selectively used for forming at least one film covering layer of each buccal product. According to the manufacturing equipment, the buccal product with a more stable filling layer structure and better release uniformity can be manufactured.

The invention discloses an oral mucosa absorption gargle tablet based on black cimicifuga foetida extract, and particularly relates to the field of pharmaceutical preparations, the oral mucosa absorption gargle tablet comprises the following components by weight: 30 wt% of a quick release layer and 70 wt% of a slow release layer; the quick release layer is prepared from black cimicifuga foetida nano-liposome, a disintegrating agent and a penetration enhancer, and the mass ratio of the black cimicifuga foetida nano-liposome to the disintegrating agent to the penetration enhancer in the quick release layer is 4: 1: 1; the slow-release layer is prepared from chitosan, soy isoflavone, a pH sensitive material and a flavoring agent, and the mass ratio of the chitosan to the soy isoflavone to the pH sensitive material to the flavoring agent in the slow-release layer is 2: 3: 1: 2. Through the double-layer structure design of the quick release layer and the slow release layer, quick effect and continuous effect of active ingredients are realized, and the oral preparation is obviously superior to a traditional oral preparation; the black cimicifuga foetida nano-liposome and the menthol-beta-cyclodextrin inclusion compound have a synergistic effect, so that the cumulative infiltration capacity of mucous membranes within 24 hours reaches 82.5%, and the transmembrane absorption efficiency of active ingredients is greatly improved.