A method for controlling well bore pressure based on
model prediction control theory and
systems theory, which belongs to the field of well bore
pressure control technique, includes: detecting a well
bottom pressure, a stand
pipe pressure, a casing pressure, an injection flow rate and an outlet flow rate during construction process, and determining the presence of overflow or leakage; if there is no overflow or leakage, then fine-adjusting the
wellhead casing pressure according to the slight fluctuations of the well
bottom pressure, the stand
pipe pressure or the casing pressure, ensuring that the well
bottom pressure, the stand
pipe pressure or the casing pressure are at a set value; if there is overflow or leakage, then using a well bore multi-phase flow dynamic model to simulate and calculate the overflow or leakage position and starting time of the overflow or leakage, predicting the variation over a future time period of the well bore pressure in the
well drilling process, and utilizing an optimization
algorithm to calculate the control parameter under a minimum of an actual well bottom
pressure difference during the future period; and repeating the optimization process for the next time period after a first control parameter is selected and set. The
present method enables the well bore pressure to be controlled within the allowable fluctuation range of a project, thus achieving precise
pressure control.