6209 results about "Thiourea" patented technology

The present invention relates to biscarbodiimides, thiourea derivatives, urea derivatives, and cross-linked hyaluronan derivatives having at least one intramolecular disulfide bond, and methods of preparation thereof. The invention also includes thiolated hyaluronan derivatives and salts thereof having at least one pendant thiol group or a modified pendant thiol group, and methods of preparation thereof. An example of a modified pendant thiol group is a sulfhydryl group linked to a small molecule such as a bioactive agent, for example a drug or pharmaceutically active moiety. A hyaluronan derivative having a sulfhydryl group linked to a pharmaceutically active moiety is useful as a sustained or controlled release drug delivery vehicle. Compositions containing the hyaluronan derivatives of the invention can reversibly viscosify in vivo or in vitro, in response to mild changes in condition, and are thus useful in ophthalmic surgery and in tissue engineering.

Methods and compositions for the treatment of pain using thiourea derivatives. Particularly disclosed are new compositions for the treatment of chronic pain, and methods for their use.

The present invention relates to 3-substituted-2-(arylalkyl)-1-azabicycloalkanes, methods of preparing the compounds and methods of treatment using the compounds. The azabicycloalkanes generally are azabicycloheptanes, azabicyclooctanes, or azabicyclononanes. The aryl group in the arylalkyl moiety is a 5- or 6-membered ring heteroaromatic, preferably 3-pyridinyl and 5-pyrimidinyl moieties, and the alkyl group is typically a C1-4 alkyl. The substituent at the 3-position of the 1-azabicycloalkane is a carbonyl group-containing moiety, such as an amide, carbamate, urea, thioamide, thiocarbamate, thiourea or similar functionality. The compounds exhibit activity at nicotinic acetylcholine receptors (nAChRs), particularly the α7 nAChR subtype, and are useful towards modulating neurotransmission and the release of ligands involved in neurotransmission. Methods for preventing or treating conditions and disorders, including central nervous system (CNS) disorders, which are characterized by an alteration in normal neurotransmission, are also disclosed. Also disclosed are methods for treating inflammation, autoimmune disorders, pain and excess neovascularization, such as that associated with tumor growth.

A nanoparticle including an inorganic core comprising at least one metal and / or at least one semi-conductor compound comprising at least one metal includes a coating or shell disposed over at least a portion of a surface of the core. The coating can include one or more layers. Each layer of the coating can comprise a metal and / or at least one semiconductor compound. The nanoparticle further includes a ligand attached to a surface of the coating. The ligand is represented by the formula: X-Sp-Z, wherein X represents, e.g., a primary amine group, a secondary amine group, a urea, a thiourea, an imidizole group, an amide group, a phosphonic or arsonic acid group, a phosphinic or arsinic acid group, a phosphate or arsenate group, a phosphine or arsine oxide group; Sp represents a spacer group, such as a group capable of allowing a transfer of charge or an insulating group; and Z represents: (i) reactive group capable of communicating specific chemical properties to the nanocrystal as well as provide specific chemical reactivity to the surface of the nanocrystal, and / or (ii) a group that is cyclic, halogenated, or polar a-protic. In certain embodiments, at least two chemically distinct ligands are attached to an surface of the coating, wherein the at least two ligands (I and II) are represented by the formula: X-Sp-Z. In ligand (I) X represents a phosphonic, phosphinic, or phosphategroup and in ligand (II) X represents a primary or secondary amine, or an imidizole, or an amide; In both ligands (I) and (II) Sp, which can be the same or different in the two compounds, represents a spacer group, such as a group capable of allowing a transfer of charge or an insulating group; Z, which can be the same or different in the two compounds, is a group chosen from among groups capable of communicating specific chemical properties to the nanoparticle as well as provide specific chemical reactivity to the surface of the nanoparticle. In preferred embodiments, the nanoparticle includes a core comprising a semiconductor material.

Cosmetic composition for care and / or makeup, comprising: 1) a liquid fatty phase comprising at least one silicone oil, structured with a gelling system comprising at least one polymer (homopolymer or copolymer) with a weight-average molecular mass ranging from 500 to 500,000, containing at least one moiety comprising: at least one polyorganosiloxane group, composed of 1 to 1000 organosiloxane units in the chain of the moiety or in the form of a graft, and at least two groups capable of establishing hydrogen interactions chosen from among the ester, amide, sulfonamide, carbamate, thiocarbamate, urea, thiourea, oxamido, guanidino, biguanidino groups, and combinations thereof, on condition that at least one of the groups is other than an ester group, the polymer being solid at room temperature and soluble in the liquid fatty phase at a temperature of 25 to 250° C., and 2) at least one film-forming silicone resin, the liguid fatty phase, the gelling system and the film-forming silicone resin forming a physiologically acceptable medium.

Cosmetic emulsion for care and / or makeup, comprising an aqueous phase and a liquid fatty phase dispersed one within the other, said liquid fatty phase comprising at least one silicone oil and being structured with at least one gelling polymer (homopolymer or copolymer) with a weight-average molecular mass ranging from 500 to 500,000, containing at least one moiety comprising: at least one polyorganosiloxane group, composed of 1 to 1000 organosiloxane units in the chain of the moiety or in the form of a graft, and at least two groups capable of establishing hydrogen interactions chosen from among the ester, amide, sulfonamide, carbamate, thiocarbamate, urea, thiourea, oxamido, guanidino, biguanidino groups, and combinations thereof, on condition that at least one of the groups is other than an ester group, the polymer being solid at room temperature and soluble in the liquid fatty phase at a temperature of 25 to 250° C., the aqueous phase, the liquid fatty phase and the gelling polymer forming a physiologically acceptable medium.

The invention relates to a preparation method for a muscle relaxing antagonistic agent sugammadex sodium. The preparation method comprises the following steps: preparing sulfydryl gamma-cyclodextrin by taking halogenated gamma-cyclodextrin and thiourea as reactants; then, initiating sulfydryl-alkene click reaction by illuminating or using an initiator on sulfydryl gamma-cyclodextrin with acrylic acid or acrylic esters or sodium acrylate so as to prepare high-purity sugammadex sodium in a water phase. According to the preparation method for the sugammadex sodium, the the operation environment is gentle, the yield is increased, and the purifying process for the final product sugammadex sodium is simpler.

The invention discloses a graphene nano sheet / MoS2 composite nano material and a synthesis method thereof. The method comprises the following steps of: preparing a graphite oxide nano sheet from graphite by using a chemical oxidation method, then dissolving molybdate into deionized water to form a solution of 0.02 to 0.07M, and adding thioacetamide or thiourea serving as a sulfur source and a reducer, wherein the mass ratio of the thioacetamide or the thiourea to the molybdate is 5:1-12:1; and adding the graphite oxide nano sheet into the solution, performing ultrasonic treatment for 1 to 2 hours so that the graphite oxide nano sheet is fully dispersed in a hydrothermal reaction solution, transferring the mixture into a hydrothermal reaction kettle, sealing, reacting for 20 to 36 hours at the temperature of between 220 and 260 DEG C, and obtaining the graphene nano sheet / molybdenum disulfide composite nano material by one-step hydrothermal synthesis, wherein the mass ratio of the graphene nano sheet to the molybdenum disulfide in the composite material is 1:2-4:1. The method has the characteristics of mild reaction condition and simple process. The synthesized graphene nano sheet / molybdenum disulfide composite nano material serving as an electrochemical lithium storage and electrochemical magnesium storage electrode material has wide application.

The present invention discloses one kind of hydrophobic associated and micro cross-linking polymer oil displacing agent and its preparation process. The hydrophobic associated and micro cross-linking polymer oil displacing agent is prepared through compounding water solution of water soluble hydrophobic associated copolymer of acrylamide / (vinyl benzene sulfonic acid and / or 2-acryl amido-2-methyl propyl sulfonic acid) / (C0-C18 alkyl styrene and / or p-phenyl styrene) in 0.1-2 g / l concentration, cross-linking agent solution in 0.01-1.0 g / l concentration, surfactant solution in 0.01-8 mmol / l concentration and solution of heat stabilizer thiourea in 0.005-1.0 g / l concentration; mixing in a mixer with stirrer and regulating the solution pH to 4-11 to obtain the polymer oil displacing agent. The polymer oil displacing agent cross links during flowing in oil reservoir to increase solution viscosity, and has excellent application foreground in oil reservoir development.

The invention discloses a molybdenum disulfide (MoS2) nano-sheet film material and its preparation methods. The film material is characterized in that MoS2 nano-sheets vertically and sequentially grow on a conductive substrate, and the diameters and the thicknesses of the MoS2 nano-sheets are 0.05-2mum and 2-30nm respectively. There are two preparation methods of the film material. One preparation method comprises the following steps: a substrate which can be a copper sheet, a silver sheet, a titanium sheet, a tungsten sheet, a molybdenum sheet or carbon is placed in a solution comprising a molybdate and sulfur-containing compounds (comprising thiourea, thioacetamide and L-cysteine); and the sulfur-containing compounds undergo a hydrothermal reaction to grow the compactly-grown and uniformly-sequential MoS2 nano-sheet films on the substrate. Another method comprises the following steps: the molybdenum sheet is directly placed in a solution of the sulfur-containing compounds (comprising thiourea, thioacetamide and L-cysteine); and the sulfur-containing compounds undergo a sulfuration reaction under a hydrothermal condition to form the compact and uniform MoS2 nano-sheet ordered films. The film has a low hydrogen evolution overpotential (-30mv), a small Tafel slope (52mV / dec) and a high electrochemical stability, and is a hydrogen evolution electrode material extremely having an application prospect.

The inventions disclosed herein relate to genuses of non-naturally occurring small molecule compounds which comprise two or optionally three organic moieties of limited size “linked” by certain structurally related “linker” functional groups. Suitable linker groups include ester, amine, ether, keto, imino, thioamide, thioether, sulfonamide, sulfonate ester, sulfone, guanidine, and thiourea groups. The compounds are capable, when contacted with comestible food or drinks or pharmaceutical compositions, at concentrations preferably on the order of about 100 ppm or lower, of serving as savory (“umami”) or sweet taste modifiers, savory or sweet flavoring agents and savory or sweet flavor enhancers, for use in foods, beverages, and other comestible or orally administered medicinal products or compositions, optionally in the presence of or in mixtures with conventional flavoring agents such as monosodium glutamate or known natural or artificial sweeteners.

Disclosed is a moisture-curing type curable resin composition containing: a curable resin intramolecularly having a silicon-containing functional group; and a Lewis acid or a complex of the Lewis acid as a curing catalyst, the Lewis acid being selected from the group consisting of metal halides and boron halides, which is rapidly cured at room temperature. The silicon-containing functional group is represented by general formula: —SiX1X2X3 or —SiR1X1X2 (wherein, X1, X2 and X3 respectively represent a hydrolytic group and may be the same as or different from each other, and R1 represents a substituted or unsubstituted organic group having 1 to 20 carbons). If the silicon-containing functional group is —SiR1X1X2, the curable resin further contains intramolecularly a polar component that is one of urethane, thiourethane, urea, thiourea, substituted urea, substituted thiourea, amide, and sulfide bonds, and hydroxyl, secondary amino and tertiary amino groups. Two-part type adhesive is constitutible with separating the curable resin from the curing catalyst.

The invention discloses a making method of carbon / molybdenum disulfide composite microball through water heat method, which comprises the following steps: dissolving molybdate in the deionized water to form 0.02-0.1m solution; adding thioacetamide or sulfourea as sulfur source with molar rate of thioacetamide or sulfourea and molybdate at 31-51; stirring evenly; adding glucose or sucrose as carbon source with the molar rate of glucose or sucrose and molybdate at 51-251; stirring completely; transmitting solution into water heat reacting autoclave to react under 200-240 deg. c for 20-24h; cooling naturally; separating; washing; drying to obtain the product.

The invention discloses an acid-cleaning inhibiter for cleaning a boiler and a use method thereof. The acid-cleaning inhibiter comprises the following components by weight percent: 2.0%-10.0% of acid liquor, 0.08-0.25% of urotropine, 0.04-0.15% of dimethylbenzene thiourea or thiourea, 0.01-0.05% of thiocyanate, 0.03-0.12% of dodecyl-cetyl phenmethyl chloride or bromide, 0.05-0.12% of a surface active agent and the balance of water. Acids suitable for the acid-cleaning inhibiter include hydrochloric acid, citric acid, sulphuric acid, hydrofluoric acid, aminosulfonic acid and phosphoric acid, which are suitable for boiler steel, mild steel, alloy steel and steam steel. The inhibition effect of the invention is over 98% with less toxicity under the boiler chemical cleaning condition, the value of LD50 (orally taken by mice) is 5.74 g / kg. The invention can be stored for 2 years, resistant Fe<3+> ion is 800 mg / kg in the acid cleaning. The preparation method has simple steps, easily obtained raw materials and convention operation.

A two-part self-curing endodontic sealing system comprises a thiourea derivative, such as acetyl thiourea, and a hydroperoxide, such as cumene hydroperoxide. The thiourea derivative is used as a reducing agent and the hydroperoxide is used as an oxidizing agent.

The invention discloses a fire-retardant cable sheath material formulation and the preparation method thereof. The formulation comprises, by weight parts, 15 to 30 parts of chloroprene rubber, 15 to 30 parts of chlorinated polyethylene, 0.5 to 3.0 parts of zinc oxide, 0.5 to 3.0 parts of magnesium oxide, 0.2 to 1.0 parts of ethylene thiourea, 0.5 to 2.0 parts of dibenzothiazyl disulfide, 0.1 to 0.5 parts of tetramethylthiuram disulfide, 0.5 to 2.0 parts of N-phenyl-2-naphthylamine, 0.5 to 2.0 parts of stearic acid, 0.5 to 3.5 parts of paraffin, 1.0 to 5.0 parts of dioctyl phthalate, 5.0 to 15 parts of carbon black with high abrasion resistance, 5.0 to 15 parts of semi-reinforced carbon black, 3.5 to 10 parts of calcium carbonate, 2.5 to 8 parts of bis(pentabromophenyl) ether, 1.0 to 3.0 parts of antimony trioxide, and 1.0 to 8.0 parts of aluminum hydroxide. The preparation method mainly comprises the following steps: plasticating, blending, mixing, thin-passing and calendaring and extruding the sheath.

The invention discloses a method for treating mercury-containing wastewater during PVC (Polyvinyle Chloride) production through a two-step process. The method comprises the following steps of: firstly, completing primary removal of mercury, copper, ferrous and ferric iron, cadmium, zinc, manganese, lead and suspending impurities of above 10mg / l by using a precipitator and a flocculating agent, regulating PH to 6-8 and then adding the flocculating agent and stirring for 30 minutes, standing for above 1 hour, discharging slag and aerating, absorbing mercury carried away by a gas phase through a sulfide adsorber, purifying water by using a plate type kieselguhr filter, removing residual suspended matters; and 2, carrying out complete reaction on the mercury in the wastewater by using an active carbon and a mercaptan and thiourea resin combining method again for being removed, and finally reaching the standard that the content of the mercury is less than 0.005mg / l. The treated wastewater can be recycled to salt melting or an acetylene generator, so that zero emission of the treated wastewater is achieved; and the mercury-containing waste acid water of hydrochloric acid desorption in the industry of chlor-alkali can be treated, the consumption of acid is reduced, and the great popularization significance is achieved in the industry of chlor-alkali.

The invention relates to a plant nutrient liquid fertilizer. In order to solve the problem of over fertilization, the plant nutrient liquid fertilizer is prepared from the following raw materials in proportion by weight: aqua brassin 12-36, gibberellin 1-4, indoleacetic acid 30-80, abscisic acid 10-20, naphthaleneacetic acid 50-90, salicylic acid 80-180, vitamin C 1-3, cane sugar 40-100, chitin 20-80, 0.05-0.2 percent triacontanol 400-1,000, hydrolyzed protein 2-5, potassium dihydrogen phosphate 300-400, thiourea 40-120, cobalt chloride 5-12, borax 50-100, sodium silicate 30-55, urea 300-500, ammonium molybdate 50-80, copper sulfate 30-65, zinc sulfate 120-200, magnesium sulfate 100-150, calcium chloride 50-120, manganese sulfate 40-80 and water in the amount of 3-8 times the total amount of all the raw materials or water in the amount capable of dissolving all the raw materials, wherein the water is de-ionized water or micro cluster water; and the preparation method is that all the materials are prepared into aqueous solution. The plant nutrient liquid fertilizer has the advantages of favorably solving the problems of over fertilization and shortage of nutrient elements in soil, obviously improving the plant adverse resistance, improving the photosynthesis and the accumulation efficiency of nutritive materials and improving the yield and the quality.

A two-component initiator system having accelerators for curing polymerizable materials comprising the following components: (a) a hydroperoxide compound containing one or more hydroperoxide groups that are bound to a tertiary carbon; (b) a thiourea derivative; and (c) as accelerator, a copper compound which is soluble in the preparation is preferably free of amine and is particularly suited for polymerizable dental compositions.

A shelf-stable two-part self-adhering dental composition and method. The composition comprises(a) at least one acidic compound containing at least one acidic moiety selected from the group consisting ofwhere R is an alkyl or aryl group;(b) at least one polymerizable monomer without any acidic group where the polymerizable group is selected from the group consisting of an acrylate, a methacrylate and a vinyl group;(c) a substituted thiourea selected from the group consisting of 1-(2-pyridyl)-2-thiourea and 1-(2-tetrahydrofurfuryl)-2-thiourea; and(d) a hydroperoxide compound with at least one hydroperoxide group attached to a tertiary carbon. The first and second parts are then mixed immediately prior to application, applied to a dental substrate, and hardened. The bond strength of the mixed composition to dentine substrate is at least 3 MPa. The composition has excellent shelf-life and is self-adhering to various dental substrates such as a tooth, metal alloy and porcelain. It can be used as a filling material, a cement, a liner / base, a pit / fissure sealant, a primer or an adhesive.

The invention relates to a preparation method for a double-metal-sulfide catalyst. Soluble molybdate and nickel salt or cobalt salt serves as a raw material, thiourea or thioacetamide serves as a sulfur source, and a Ni(Co)-S / MoS2 catalyst is prepared through a two-step hydrothermal method. The method particularly comprises the following steps: MoS2 is prepared in a high pressure reactor through the hydrothermal method first, then the nickel salt or cobalt salt and the sulfur source are added into the reactor of the obtained MoS2 to be evenly mixed, the reactor is sealed and heated, a reaction is conducted for a certain period of time, and Ni-S or Co-S is deposited on the MoS2, so that the Ni(Co)-S / MoS2 catalyst is prepared. The preparation method is characterized in that the specific area of the Ni(Co)-S / MoS2 catalyst prepared through the two-step hydrothermal method is large, high temperature vulcanization is not required in the preparation process, the preparation condition is mild, the catalyst is used for hydrodeoxygenation, a target product has high yield and good repeatability, and hydrodeoxygenation activity of the catalyst is high.

The invention relates to a nitrogen-sulfur double-doped carbon material difunctional oxygen catalyst, a preparation method thereof and electrocatalysis application of alkaline medium in oxygen. In the catalyst, ocean polysaccharide sodium alginate is used as a carbon source, thiourea is sources of nitrogen and sulfur atoms, and double doping is performed on N and S which have electronegativity by high-temperature calcination in an inertia atmosphere to obtain a nitrogen-sulfur double-doped carbon material electrocatalyst. Since a double-doped crystal structure of heteroatoms is changed, the specific area and the catalyst site of the catalyst are improved, meanwhile, relatively high oxygen evolution (OER) and oxygen reduction (ORR) catalytic activity are achieved, and the overoptential of OER and ORR is effectively reduced; the ORR process is most divided to four electron catalytic mechanisms and is an relatively ideal ORR reaction process, and the catalyst has favorable stability and excellent methyl alcohol resistance; and the used raw material is low in cost, the preparation method is simple and is easy to operate, and mass production is facilitated.

The invention discloses a making method of MoS2 microball synthesized by ionic liquid auxiliary water, which comprises the following steps: dissolving molybdate in the deionized water to form 0.05-0.1m solution; adding thioacetamide or sulfourea as sulfur source with molar rate of thioacetamide or sulfourea and molybdate at 31-51; stirring evenly; adding 1-butyl-3-methyl imidazole tetrafluoride borate as ionic liquid with the bulk rate of ionic liquid and synthetic solution at 1300-1 50; stirring completely; transmitting solution into water heat reacting autoclave to react under 200-240 deg. c for 20-24h; cooling naturally; separating; washing; drying to obtain the product.

A process for preparing the solution and solid of ceratin includes extracting ceratin from wool of goat and sheep, camel hair, feather, leather leftover, etc by reduction method, and preparing solution and solid by use of the reagent, such as inorganic salt, urea, or thiourea.

The invention relates to a graphene-supported layered MoS2 (molybdenum disulfide) nanocomposite and a preparation method thereof, belongs to the technical field of preparation of nano materials, and is used for solving the problem that graphene-supported MoS2 nanoparticles prepared in the prior art are poorer in catalytic performance due to small composite areas between the nanoparticles and graphene. Ammonium molybdate and thiourea are taken as initiators, and layered nano MoS2 can be supported on the surface of graphene oxide under the hydrothermal condition; after roasting treatment, the graphene-supported layered MoS2 has the higher crystallinity, and the photocatalytic efficiency is more than 1.7 times that of commercial nano titanium oxide. The method is simple and easy to operate; MoS2 nanosheets are uniformly distributed on the surface of the graphene and have larger contact areas with the graphene, so that the nanocomposite has the high catalytic performance and is widely applied to fields of electro-catalysis, photo-catalysis, hydrogen evolution catalysis and the like.

The invention provides a metal surface oil and rust removal agent, and belongs to the technical field of cleaning agents. The metal surface oil and rust removal agent comprises the following components by weight: 2 to 4 parts of hydrochloric acid, 5 to 10 parts of phosphoric acid, 3 to 6 parts of oxalic acid, 3 to 5 parts of glacial acetic acid, 2 to 4 parts of citric acid, 3 to 4 parts of polyvinyl alcohol, 1 to 2 parts of hexamethylene tetramine, 2 to 3 parts of ethylene oxide, 1 to 2 parts of glyoxal, 2 to 3 parts of magnesium stearate, 2 to 4 parts of glycerol, 2 to 4 parts of thiourea, 2 to 4 parts of ammonium molybdate, 1 to 2 parts of polyaspartic acid, 2 to 4 parts of EDTA-Na2, 1 to 2 parts of ethylene diamine tetra sodium, 1 to 3 parts of poly maleic acid sodium, 2 to 3 parts of HEDPA, 2 to 6 parts of surface active agent and 70 to 100 parts of water. The metal surface oil and rust removal agent is convenient to use, and removes light rust for about 2 minutes and heavy rust for 6 to 7 minutes, and the oil removal rate can reach more than 97%.

The invention relates to a dissolvent for quick-speed direct dissolution of cellulose which comprises sodium-hydroxide and the water solution of sulfourea, wherein sodium-hydroxide amounts to 8.1-12.0% of the total water solution weight in the dissolvent, and sulfourea amounts to 3.0-6.0A% of the total water solution weight. The invention also provides a process for quick-speed direct dissolution of cellulose.

The invention relates to a quick, energy-saving and high-yield preparation method of quasi-graphite-structure carbon nitride catalysis materials and application of the materials, belonging to the field of preparation and application of catalysis materials. According to the preparation process, one or multiple nitrogen-rich small organic molecules of urea, melamine, thiourea, cyanamide, dicyanamide, cyanuric chloride and cyanuric acid is / are taken as raw materials, a simple metal substance, a metallic oxide, a metal sulfide and a metal chloride are taken as microwave absorbers, microwave is taken as a heating source, and under the condition of radiation of microwave, the quasi-graphite-structure carbon nitride material can be quickly prepared. The prepared carbon nitride material has a large specific area and crystallinity and has high photocatalytic water decomposition hydrogen production performance and organic pollutant degradation performance. The preparation method provided by the invention is short in time, small in energy consumption, high in production efficiency and simple in process, does not have harsh preparation conditions, is easy to operate and has wide application prospect.

The invention discloses 4-(benzofuran-5-yl)-2-benzal aminothiazole as shown in a chemical structural formula I. The preparation method of the 4-(benzofuran-5-yl)-2-benzal aminothiazole is as follows: 1-(7-hydroxy / alkoxy-2,2-dimethyl-2,3-dihydro-benzofuran-5-yl) butanone is subject to bromination and reacts with thiourea to obtain 4-(7-hydroxy / alkoxy-2,2-dimethyl-2,3-dihydro-benzofuran-5-yl)-2-aminothiazole which reacts with aromatic aldehyde to prepare the 4-(benzofuran-5-yl)-2-benzal aminothiazole. The 4-(benzofuran-5-yl)-2-benzal aminothiazole has good activity inhabiting activity on Hela cells, human liver cancer cells (Bel 7402 cells) and lung carcinoma cells (A549 cells) and can be used for preparing the antineoplastic agent.