The invention discloses quinquagenarian formula health rice flour and a preparation method thereof. The quinquagenarian formula health rice flour which is suitable for quinquagenarian and diabetes is prepared through puffing, crushing, sieving, blending, packaging and the like by taking 10-12 percent of embryos of giant embryo rice, 8-10 percent of wheat embryos, 15-18 percent of selenium-rich giant embryo coarse rice, 5-8 percent of black rice testa, 5-8 percent of red rice testa, 5-7 percent of kelp, 4-6 percent of laver, 5-8 percent of black sesame, 8-10 percent of lotus seeds, 8-10 percent of sunflower seeds, 8-12 percent of skimmed milk powder and 4-6 percent of isomaltose hypgather as raw materials. The health rice flour is rich in Gamma-aminobutyric acid, selenium, calcium, rice peptide, glutathione, flavonoids compounds, alkaloid, amino acids, microelements, vitamins, carotene, anthocyanin, cardiac glycoside and other functional components and has the capabilities of improving immunity and preventing senile dementia, caners, high blood pressure and other cardiovascular diseases after being eaten for a long time.