8 results about "Skin penetration enhancer" patented technology

The invention relates to thymol-containing hoof bath lotion and a preparation method thereof, the hoof bath lotion comprises the following components in percentage by mass: greater than or equal to 22% of thymol, 22%-27% of a non-aqueous solvent, 10%-12% of a transdermal absorbent, 21%-27% of a surfactant, 0.01%-1.0% of a coloring agent, 0.01%-1.0% of a complexing agent and the balance of water, the surface active agent comprises a first surface active agent, a second surface active agent and a third surface active agent, and the number of the transdermal absorbents is at least two. The hoof bath lotion is high in safety, good in stability and free of obvious irritation, hoof diseases in different stages can be effectively prevented and controlled, the administration condition can be visually marked, omission or repeated administration is avoided, and pasture management is facilitated.

The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry and application, and relates to the technical field of biological medicine and functional skin care. The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry. The skin care product is prepared from the following components in parts by mass: 0.5 to 3 parts of spermidine, 0.2 to 2 parts of an autophagy activator, 0.5 to 4 parts of an antioxidant, 0.1 to 2 parts of a mitochondrial function accelerant, 0.2 to 3 parts of a microcirculation accelerant, 1 to 6 parts of a skin penetration accelerant, 0.2 to 1 part of a preservative, 0.05 to 0.4 part of a pH regulator and 60 to 95 parts of a carrier matrix. The composition can effectively reduce the aging rate of hair follicle stem cells and remarkably improve the proliferation activity of the hair follicle stem cells, active oxygen free radicals around the hair follicle stem cells can be effectively removed by adding the antioxidant of a novel structure, damage of external stimulation to hair follicles is reduced, and a systematic cell protection and repair mechanism is formed.

The present invention provides a cosmetic composition comprising a sebum secretion-regulating and anti-inflammatory functional mRNA nanocomplex as an active ingredient, and use thereof. Specifically, the present invention relates to a cosmetic composition comprising a sebum secretion-regulating and anti-inflammatory functional nanocomplex comprising mRNA as an active ingredient. The nanocomposite comprises (a) an inner core composed of a complex of the mRNA active ingredient and a cationic substance; (b) an intermediate layer surrounding the inner core, containing a lipid and a skin penetration enhancer; and (c) an outer layer surrounding the intermediate layer made of a polymer having pH and enzyme reactivity. The nanocomposite of the present invention exhibits excellent effects in inhibiting skin sebum secretion and reducing inflammatory reactions. Furthermore, the multilayer structure design increases the stability of the active ingredient, enabling it to efficiently pass through the skin barrier to reach the target area.

The present invention provides a topical formulation comprising active ingredient(s) lidocaine, ketamine, or pharmaceutically acceptable salt thereof for dermal application and method of use to treat or relieve pain. The topical formulation comprises active pharmaceutical agents lidocaine, ketamine, or their pharmaceutical salt thereof; one or more skin penetration enhancers; and a drug delivery matrix system. The topical formulations are aimed at relieving pain including any type of pain in body, joint pain, chronic pain states such as post-herpetic neuralgia, complex regional pain syndrome, and arthritis. The topical formulation dries and forms a clear film on the skin and as it comprises water insoluble excipients, it is reasonably wash resistant.

The instant disclosure relates to compositions, especially cosmetic composition, in particular for caring for keratin materials. The cosmetic compositions include at least one skin penetration enhancer; at least three natural moisturizing factors; hydroxyethylpiperazine ethane sulfonic acid. The compositions are useful in methods for improving the appearance of keratin materials.

A method for enhancing penetration of a royal jelly into a skin includes blending a carrageenan into a cosmetic composition including the royal jelly. A method for enhancing penetration of a royal jelly into a skin also includes applying a cosmetic composition including a carrageenan and the royal jelly on the skin. A method for producing a cosmetic composition including a royal jelly includes blending a carrageenan into the cosmetic composition for enhancing penetration of the royal jelly into a skin.

The instant disclosure relates to compositions, especially cosmetic composition, in particular for caring for keratin materials. The cosmetic compositions include at least one skin penetration enhancer; at least three natural moisturizing factors; hydroxyethylpiperazine ethane sulfonic acid. The compositions are useful in methods for improving the appearance of keratin materials.

The invention relates to an anti-aging composition containing umbilical cord stem cell extract and a preparation method of the anti-aging composition. The composition consists of an umbilical cord stem cell extract, a natural antioxidant, a stabilizer, a skin penetration enhancer and deionized water or a biocompatible solvent, and placenta polypeptide, a basic fibroblast growth factor (bFGF) and an epidermal growth factor (EGF) can also be added as synergistic components. The preparation method comprises the following steps: mixing the components under the protection of inert gas, homogenizing, defoaming, filling, sterilizing and the like. The composition provided by the invention has the advantages of remarkable anti-aging effect, high stability, good safety, high bioavailability and various dosage forms, and can meet different use requirements.