Disclosed is a Chinese medicine prescription for treating talagia, which is prepared from the following active pharmaceutical ingredients by weight: 15g of radix angelicae sinensis, 15g of radix rehmanniae preparata, 12g of cornus officinalis, 15g of white peony root, 30g of achyranthes root, 15g of radix paeoniae rubra, 12g of peach seed, 12g of safflower, 30g of caulis spatholobi, 30g of herba lycopodii, 30g of semen coicis, 20g of rhizoma drynariae, 12g of fructus psoraleae, 30g of radix dipsaci, 10g of frankincense, 10g of myrrh and 10g of prepared radix glycyrrhizae. The Chinese medicine prescription for treating talagia is provided in that the traditional Chinese physicians think the talagia mostly caused by inherent defect, renal deficiency, emotion disturbance and excessive sexual intercourse. The calcar pedis is the place where the Shenjing point goes, whose pain is caused by kidney deficiency, the liver failing to be nourished, liver controlling tendon, liver-blood deficiency, the tendon failing to be nourished, blood stasis, sukra prameha, cold hygrosis invasion and vein imbalance. For the above disease causes, in the prescription the selected medicines are stressfully required to be Yin meridian medicines for tonifying the liver and the kidney, promoting qi to activate blood, excreting dampness to dissipate cold, and alleviating pain. The active ingredients of the medicines are built up to cooperate the medicines to have the curative effect doubled, which is a Chinese medicine prescription with special efficacy for treating talagia. The Chinese medicine prescription has been clinically applied for many years to cure hundreds of patients, which has the advantages of reliable and obvious curative effect, gentle drug property and no toxic side effect, with effective rate up to 90% and cure rate 80%.