164 results about "Appetite" patented technology

This invention relates to treating Prader-Willi Syndrome (PWS) using a KATP channel opener. The channel opener may be coadministered with other therapies used to treat PWS, such as human growth hormone, a wakefulness promoting agent, or a psychiatric or mood stabilizing drug, thereby allowing the baseline dosages of these other therapies to be decreased or making these other therapies unnecessary. The invention also relates to treating PWS based on the PWS nutritional phase of a patient, to prevent the patient's PWS nutritional phase from progressing or shift the patient's PWS nutritional phase back to an earlier phase. The invention further relates to treating PWS, and conditions associated with low basal metabolic rate or hyperphagia, with the KATP channel opener based on a patient's blood ketone levels.

A traditional Chinese medicine composition for alleviating gastrointestinal toxic side effects caused by chemotherapy, the traditional Chinese medicine composition for daily administration is prepared from the following weight ratio of traditional Chinese medicine formula: Taizishen 20-30g, Fuling 10-15g, Fried Baizhu 10-15g, Zhigancao 5-10g, Jiangbanxia 5-10g, Chenpi 5-15g. The formula can effectively alleviate the gastrointestinal toxic side effects caused by chemotherapy, such as nausea, vomiting, diarrhea, poor appetite, etc.

The invention relates to a spleen-tonifying, appetite-stimulating and digestion-promoting traditional Chinese medicine preparation UPLC detection method and a fingerprint spectrum, and belongs to the technical field of medicine detection. The invention aims to solve the technical problems that the existing quality control method of the spleen-tonifying, appetite-promoting and digestion-promoting pills lacks comprehensive and objective analysis on the spleen-tonifying, appetite-promoting and digestion-promoting pills, and the problems of low precision, poor reproducibility, low efficiency and the like during detection of related components in the prior art are solved. According to the technical scheme, the UPLC detection method is characterized in that a mixed standard substance of gallic acid, 5-hydroxymethylfurfural, chlorogenic acid, sinapine thiocyanate, sinapic acid, hyperoside, 3, 6-dimustard acyl sucrose, hesperidin, naringenin, nobiletin and hesperetin is taken as a contrast, an acetonitrile-0. 1% formic acid aqueous solution is taken as a mobile phase, gradient elution is carried out, and the content of chlorogenic acid in the sample is detected. The qualitative and quantitative detection of the effective components of the spleen-tonifying, appetite-promoting and digestion-promoting pill is realized.

The present invention relates to pharmaceutical combinations for treating or preventing insulin resistance and associated disorders, in particular the use combinations comprising a 4-epimerase inhibitor and a GLP-1 receptor agonist for treating or preventing insulin resistance and associating disorders such as obesity and type-2 diabetes, supressing appetite and / or promoting weight loss.

To provide compositions and methods for treating and preventing cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, and addiction.SOLUTION: Also provided are methods for the diagnosis and monitoring of cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, addiction, and other conditions such as convulsion or seizure. These compositions comprise fatty acid compounds and salts thereof which may be administered either alone, in combination with other medicaments, or as part of various treatment regimens. The provided compositions are effective for modulating markers, including, but not limited to, behavior associated with cognitive impairment, movement disorders, chronic pain, depression, decreased appetite, opiate addiction, and other related conditions. Methods for administering the compositions are also provided.SELECTED DRAWING: Figure 1

The present invention provides methods of using non-naturally occurring melanocortin analogs to increase body weight and / or increase food consumption in a subject having a kidney disease and / or a liver disease (e.g., chronic kidney disease, renal failure, non-alcoholic fatty liver disease (NAFLD)). Also provided are methods of stimulating appetite in a subject via administration of a non-naturally occurring melanocortin analogue. The non-naturally occurring melanocortin analogs may be present in pharmaceutical compositions and delivered via parenteral administration (e.g., subcutaneous injection). The methods improve appetite, increase food consumption, increase body weight, muscle mass, and / or fat mass in the subject.

The application provides a traditional Chinese medicine composition for treating diarrhea, and relates to the technical field of traditional Chinese medicine pharmacy. The application provides a traditional Chinese medicine composition for treating chronic diarrhea, which is prepared from madder, yuyulang, camphor tree bark, white peony root, jujube, licorice, lily, trichosanthes root and heron herb. The drugs are used together to have the functions of tonifying the spleen and stomach, astringing the lung to stop diarrhea and warming the middle and promoting qi. The traditional Chinese medicine composition can effectively relieve and improve the clinical symptoms of patients with chronic diarrhea, such as diarrhea, loss of appetite, lassitude and fatigue, and has a remarkable curative effect, so it is worthy of further clinical promotion and application.

The utility model discloses a built-in double-layer lunch box and relates to the technical field of lunch boxes. The lunch box comprises a lunch box body, second springs are installed on the inner walls of the two sides of the lunch box body, a first supporting frame and a second supporting frame are connected into the lunch box body, a first spring is connected between the first supporting frame and the lunch box body, and a first containing box and a second containing box are placed on the top of the first supporting frame and the top of the second supporting frame respectively. The top of the meal box body is connected with a box cover through a lock catch. According to the meal box, the first containing box and the two second containing boxes are arranged, the first containing box is used for containing staple food, the two second containing boxes are used for containing dishes, and therefore the containing capacity of the meal box is increased, the meal box can contain more meals, meanwhile, the first meal box body and the second meal box body are used for containing the meals respectively, and the meal box is convenient to use. Therefore, the food is prevented from being mixed together in the transportation process to affect the appetite during later eating.

The invention provides a process for preparing a plasticised superporous hydrogel material comprising subjecting initial hydrogel material to treatment with an acidic solution, an optional treatment with a monovalent metal salt solution, freeze drying and plasticisation. Optionally, the process of the invention produces moulded plasticised superporous hydrogel material bodies that have one or more through-holes formed therein. The plasticised superporous hydrogel material of the present invention may be formulated as a suitable oral dosage form for use an appetite suppressant and for use to deliver a pharmaceutical and / or nutraceutical into a human or animal body.

Provided herein are methods of treating, preventing, or reducing conditions and / or side effects associated with anti-cancer agents (e.g., chemotherapeutic agents) via administration of a non-naturally occurring melanocortin analog prior to, during, and / or after administration of the anti-cancer agents. The methods reduce adverse effects associated with the anti-cancer agent, such as anorexia, weight loss, muscle mass loss, fat mass loss, wasting, reduced appetite, and loss of appetite, thereby enhancing tolerance of the anti-cancer agents and survival of the subject having cancer or having a disease or condition that is not cancer but is treated, reduced, or prevented by administration of an anti-cancer agent.

The invention relates to the technical field of health-care herbal tea, in particular to a formula and a using method of spleen-tonifying and kidney-tonifying herbal tea. The traditional Chinese medicine is prepared from the following raw materials by weight: 6-11g of radix pseudostellariae, 6-11g of rhizoma atractylodis macrocephalae, 6-11g of poria cocos, 3-6g of liquorice, 6-10g of ginger processed pinellia, 6-11g of pericarpium citri reticulatae, 9-13g of angelica sinensis, 6-10g of rehmannia, 6-11g of polygala tenuifolia, 6-13g of fructus alpiniae oxyphyllae, 11-16g of tortoise plastron, 6-13g of rhizoma drynariae, 9-14g of vinegar turtle shell, 10-16g of rhizoma cibotii, 9-13g of dipsacus root, 6-13g of dendrobe, 9-16g of sanguisorba officinalis and 6-11g of rhizoma cimicifugae. Liujunzi decoction is matched with radix angelicae sinensis and radix rehmanniae to construct a qi-blood tonifying basis, and cooperates with tortoise plastron, vinegar turtle shell and rhizoma drynariae to fill kidney essence and strengthen tendons and bones, meanwhile, the rhizoma cimicifugae is combined to enhance the qi lifting effect of ginseng, and symptoms of inappetence, abdominal distension and sticky stool caused by spleen deficiency and dampness stagnation and soreness and weakness of waist and knees and weakness of limbs caused by kidney deficiency and bone weakness are synchronously improved.

The invention discloses a breeding feed based on a traditional Chinese medicine compound additive for meat improvement, and belongs to the technical field of livestock and poultry breeding feeds, the breeding feed comprises a basic concentrate supplement and the traditional Chinese medicine compound additive, and the traditional Chinese medicine compound additive is divided into an early fattening stage additive and a middle and later fattening stage additive according to the growth stage of fattening sheep; traditional Chinese medicine compound additives with different proportions are designed according to the physiological characteristics of the fattening starting period of the fattening sheep 30 days before and the rapid fattening period of the fattening sheep 30 days after, hawthorn fruits, malt and folium cortex eucommiae are used as main materials in the fattening early stage, focuses on appetizing and digestion promotion, and a growth foundation is laid; eucommia ulmoides leaves and mulberry leaves are used as main materials in the middle and later fattening periods, hawthorn fruits, dried tangerine or orange peel and liquorice are matched, fat control, muscle building and cavity oil degradation are focused on, and especially the problem of cavity oil degradation of ewes is solved in a targeted mode.

1. Name of the design product: dog food (similar series). 2. Use of the design product: dog food for dogs to have more appetite. 3. Design points of the design product: combination of shape and pattern. 4. Picture or photo that best indicates the design points: design 1 front view. 5. Design 1 is designated as the basic design.

The present application relates to the technical field of bioactive peptides, and in particular to an oat oligopeptide, preparation thereof and application thereof in preparing a product for regulating the expression of brain appetite suppressor factor. The oat oligopeptide can effectively stimulate the release of cholecystokinin (CCK) from intestinal endocrine cells, and stimulate the central nervous system through the vagus nerve pathway, thereby promoting the expression of the appetite suppressor factor pro-opiomelanocortin (POMC) in the hypothalamus. Compared with the prior art, the oat oligopeptide has the advantages of stable structure, high safety, simple preparation process (conventional enzymatic hydrolysis and chromatographic purification can achieve the preparation), easy scale production and the like. The oat oligopeptide is suitable for being used as a functional ingredient or a drug precursor to develop a related health product with the functions of regulating appetite and promoting satiety, and has a wide application prospect in the field of preparing functional products (food, medicine and the like).

A composition comprising a soy protein isolate, a soy fibre, a phospholipid, and a carbohydrate for use in the treatment or prevention of obesity, type 2 diabetes or cardiovascular disorders, wherein the composition is administered together with a first pharmaceutical composition comprising an appetite suppressant agent.

The invention provides a feed additive and compound feed for improving intramuscular fat of pork, and belongs to the technical field of animal feed. The additive consists of the following components in parts by mass: 30-40 parts of codonopsis pilosula, 20-25 parts of rhizoma atractylodis, 12-16 parts of folium eriobotryae, 10-15 parts of bighead atractylodes rhizome, 10-15 parts of poria cocos, 8-12 parts of hawthorn, 18-22 parts of pomegranate rind and 5-10 parts of liquorice. The feed additive disclosed by the invention can effectively solve the problem that the meat quality and flavor of modern commercial pigs are reduced due to high lean meat percentage breeding through the synergistic effects of tonifying spleen, promoting appetite, promoting nutrient absorption and regulating metabolism. When the feed additive is applied to live pig feeding, the average daily gain and the meat-feed ratio of pigs can be remarkably increased on the premise that the thickness of back fat is not increased, meanwhile, the carcass lean meat percentage, the marbling score and the intramuscular fat content are increased, and the yield and the edible flavor of pork are comprehensively improved.

The invention discloses a depression-relieving and liver-soothing pill and a preparation method thereof, and belongs to the technical field of Chinese patent medicines. The depression-relieving and liver-soothing pill comprises the following active ingredients: vinegar-processed rhizoma cyperi, grape seeds, bran-fried rhizoma atractylodis macrocephalae, poria cocos, hawthorn, pericarpium citri reticulatae, ginger-fried fructus gardeniae, vinegar-processed rhizoma corydalis, fructus aurantii, betel nuts, liquorice, medicated leaven, pericarpium citri reticulatae viride, radix aucklandiae, fructus amomi and radix linderae. According to the invention, the alcohol extract of the grape seeds is added into the traditional depression-relieving and liver-soothing pill, so that the depression-relieving and liver-soothing pill is obviously improved in the effect of enhancing the activity of pepsin and pancreatin, and a better instant curative effect can be obtained when the depression-relieving and liver-soothing pill is used for treating chest and hypochondrium fullness, inappetence and other symptoms.

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.

The invention relates to the technical field of medicines, in particular to combined application of semeglutide and sodium butyrate in preparation of a medicine for reducing weight. Experimental results show that when the semeglutide and the sodium butyrate are combined for use, the appetite inhibition effect can be synergistically enhanced, and the body weight and the fat weight of a mouse are remarkably reduced.

The invention provides a method for preparing pet meat feed through an enzymolysis technology and application of the pet meat feed, and belongs to the technical field of pet feed preparation. Aiming at the problems of low digestibility and poor taste of the existing pet meat feed, meat is subjected to enzymolysis and fermentation treatment, so that the taste of the meat feed is improved, the appetite is improved, the meat feed is easy to digest, and nutrient absorption is promoted. On the basis of meat, enzymolysis beans, sweet potato starch, spirulina powder, a traditional Chinese medicine compound, fish oil, probiotics and an additive are added. Wherein the sweet potato starch can provide energy and improve the texture and palatability; the spirulina powder is rich in nutrition, so that the palatability is improved; the traditional Chinese medicine compound stimulates the appetite and improves the appetite of pets; the probiotics accelerate decomposition, digestion and absorption of the feed; the fish oil improves the overall flavor and taste. Experiments show that all the components have a synergistic effect, the feed intake rate, the preferred rate and the feed intake of pets can be remarkably improved, the apparent digestibility of protein can be remarkably improved, and absorption of the protein can be promoted.

This invention discloses a composition containing eicosenoic acid and its glycerides, and its applications. At least one of eicosenoic acid and its glycerides is selected as the main active ingredient, enabling the obtained composition to produce a synergistic effect, significantly enhancing physiological activities such as controlling body fat, regulating intestinal flora, maintaining blood lipids / blood sugar / blood pressure, protecting the liver, controlling appetite, anti-oxidation, and anti-aging. Furthermore, all components in this composition are derived from pure natural plants, with no toxic side effects; and the preparation method is simple and easy to operate, making it suitable for preparing related health foods, pharmaceuticals, feed, and feed additives, showing promising application prospects.

The invention discloses a preparation method of an acupoint patch helpful for height increase of children, three therapies of tonifying spleen, helping sleep and tonifying kidney are creatively integrated through a spleen-tonifying and appetite-stimulating patch, a nerve-soothing and sleep-helping acupoint patch and a kidney-tonifying and collateral-dredging acupoint patch, the specially-made plaster is applied to the corresponding acupoint, and the acupoint patch is capable of regulating spleen and stomach functions and improving sleep by dredging channels and collaterals and running qi and blood. Development of bones and muscles of children is facilitated, so that the purpose of promoting growth is achieved; by stimulating the growth ability of children, the application curative effect is obvious.

The application discloses a composition containing sesame lignan compounds and application thereof, and selects at least one of sesame lignan or similar compounds, glycoside compounds as a main active ingredient, so that the obtained composition can significantly improve physiological activities in the aspects of controlling fat in vivo, regulating intestinal flora, maintaining blood fat, blood sugar, blood pressure, protecting liver, controlling appetite, antioxidation and anti-aging, etc. Compared with single components, two or more than two compound combinations have a better synergistic effect. Meanwhile, the components in the composition are pure natural plant food raw materials, and have no toxic side effects. Therefore, the composition has a good application prospect.

The utility model discloses an electric lifting cabinet frame which comprises a fixed upper eave, a cabinet body, a sliding device, a lifting device, a cabinet body supporting frame, a control panel and a lighting device. Through driving of the lifting device, the automatic lifting function of the cabinet is achieved, a user can take articles at high positions conveniently, the space utilization rate of a kitchen is remarkably increased, and meanwhile the cabinet can meet the requirements of people with different heights; due to the split design of the sliding device and the cabinet body supporting frame, the weight is reduced, and meanwhile good bearing capacity and stability are still achieved; the design of the lighting device can not only enhance the color sense of food and improve appetite, but also improve the cleanliness of a room. By means of the wrapping design of the upper eave and the cabinet body, the installation part is completely hidden in the cabinet, the overall visual enjoyment of a room is greatly improved, and unprecedented convenient experience is brought to a user.

The present invention relates to the field of pharmacy, and in particular to compounds of formula (I) as pharmaceutically active compounds. Compounds of formula (I) have been proven for the first time to be particularly useful for the treatment of depression and eating disorders related to depression, or diseases with depressive pathology as well as for the treatment of appetite related side effects of antidepressants and antipsychotics.

The present application provides a soluble dietary fiber composition, its preparation method and application. After the soluble dietary fiber composition enters the colon, the ester bond in the alanine modified pectin is rapidly degraded, part of the chlorogenic acid is released, the secretion of anorectic hormone is stimulated, the appetite is reduced, and the heat intake is reduced; the remaining amide bond network is slowly degraded, realizing the slow and continuous release of chlorogenic acid. Lutein removes free radicals generated by fat decomposition, reducing the oxidative damage of L cells. Galactomannan and alanine modified pectin-glucan modified protein-chlorogenic acid ternary complex synergize to improve the molar ratio of butyric acid / propionic acid: propionic acid enhances satiety through intestinal gluconeogenesis, and butyric acid stimulates the secretion of GLP-1 / PYY, realizing endogenous appetite suppression. Galactomannan absorbs water to form a lubricating gel, softening the stool and increasing the stool volume; the ternary complex degrades to produce short-chain fatty acids, optimizing the intestinal microenvironment and enhancing gastrointestinal peristalsis, both of which synergistically improve constipation.

The invention discloses a construction method and application of a zebra fish inappetence model, and belongs to the field of medicine and health food evaluation. According to the method, a zebra fish inappetence model is constructed, the water temperature, the light-dark alternating rhythm, the conductivity and the illumination intensity are adjusted, the appetite and normal growth and development of zebra fish are synergistically inhibited, the scheme is easy to operate, other interference factors are few, the result is more accurate, and the requirement for appetite promotion efficacy evaluation in the fields of food, health care products, medicines and the like can be met.

Use of Shenling Baizhuang in the manufacture of a medicine for treating after-effects of a patient infected with the novel coronavirus after recovery, wherein the after-effects are at least one selected from shortness of breath, physical weakness, loss of appetite, and diarrhea, and the raw materials for Shenling Baizhuang consist of the following parts by weight of traditional Chinese medicines: 400 parts of ginseng, 400 parts of Poria cocoon, 400 parts of fried wheat flour atractylodes, 400 parts of Chinese yam, 300 parts of fried white beans, 200 parts of lotus seeds, 200 parts of fried wheat flour job seeds, 200 parts of sand seeds, 200 parts of Platycodon grandiflorum, and 400 parts of licorice.

The invention provides a carptorelin preparation as well as a preparation method and application thereof, and belongs to the technical field of veterinary chemical preparations. The carptorelin preparation disclosed by the invention is prepared from a carptorelin-cyclodextrin inclusion compound, a diluent, a disintegrating agent, an adhesive, a lubricant, a flow aid and a flavoring agent. The prepared carptorelin preparation not only can enhance the stability of the active pharmaceutical ingredient carptorelin, but also can promote the dissolution of the carptorelin in the preparation, improve the bad flavor of the carptorelin, improve the palatability and the bioavailability of the carptorelin, has remarkable effects in the aspects of stimulating the appetite of pets, increasing food consumption and the like, and has a wide clinical prospect.

A compound comprising a peptide chain which is an analogue of amylin, a terminal —NH2 group bound to the C terminal of the peptide chain, and an alkylene or alkenylene chain attached at the other end of the peptide chain or a derivative of the compound; or a salt or solvate of the compound or of the derivative. Compounds, derivates and salts, and related compositions are suitable for the prevention or treatment of diabetes, obesity, heart disease, stroke and non-alcoholic fatty liver disease, improving insulin release in a subject, improving carbohydrate metabolism in a subject, improving the lipid profile of a subject, improving carbohydrate tolerance in a subject, reducing appetite, reducing food intake, and / or reducing calorie intake, and related purposes.