The invention provides a composition for improving mental disorder and a preparation method thereof, and belongs to the technical field of medicines.
Dendrobium officinale, poria cocos, Chinese dates and
schisandra chinensis are subjected to
water extraction and
alcohol precipitation to obtain water-extracted
traditional Chinese medicine polysaccharide, filtrate is dried to obtain a water extract, filter residues are fermented to obtain
probiotic liquid, fermented
traditional Chinese medicine polysaccharide and a fermented extract respectively,
melatonin and
paroxetine are embedded in the fermented
traditional Chinese medicine polysaccharide, hydrophobic modification is performed, hydrophobic modified embedded particles are prepared, and the
probiotic liquid, the fermented traditional Chinese
medicine polysaccharide and the fermented extract are subjected to
freeze drying to obtain the
probiotic powder. The preparation method comprises the following steps: carboxylating water-extracted traditional Chinese
medicine polysaccharide, embedding probiotics to obtain probiotic embedded microspheres, and uniformly mixing the probiotic embedded microspheres with hydrophobic modified embedded particles, a water extract and a
fermentation extract to prepare the composition for improving mental disorder. The
mental state and the emotional state of people are improved through the brain-intestine axis, the traditional Chinese medicines nourish yin to regulate the state of the
human body, the compliance of patients is improved, the
medicine effect is improved, and meanwhile the cost of the medicine is reduced.