137 results about "Lipolysis" patented technology

The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy.

Synergistic anti-adipogenic and pro-lipolytic compositions for the prevention and amelioration of adipogenesis and lipolysis mediated diseases, comprising at least two extracts selected from enriched demethylated curcuminoids obtained from Curcuma longa, Moringa oleifera and Murraya koenigii. The anti-adipogenic and pro-lipolytic compositions optionally contain one or more anti-obesic agents. These compositions are useful for preventing anti-inflammatory and free radical mediated diseases.

The invention provides analogs of PYY. The invention also provides compositions and methods useful for controlling biological activities such as cell proliferation, nutrient transport, lipolysis, and intestinal water and electrolyte secretion.

The present invention relates to a modified enzyme with lipolytic activity, a lipolytic enzyme capable of removing a substantial amount of fatty matter during a one cycle wash, a DNA sequence encoding said enzymes, a vector comprising said DNA sequence, a host cell harbouring said DNA sequence or said vector, and a process for producing said enzymes with lipolytic activity.

The invention provides a slimming composition. The effective components of the composition comprise a cereus extract, a green tea extract and a guarana extract. The composition is compounded from the cereus extract, green tea extract and guarana extract, wherein the cereus extract can regulate the activity of lipase, promote excessive fat to be quickly decomposed, and effectively prevent the fat from being absorbed by the intestinal tract, thereby achieving the slimming effect; the green tea extract has the functions of lowering and consuming the enzyme activity, reducing the food intake and energy absorption and increasing the lipolysis and metabolism; the guarana extract can increase the rate of metabolism, enhance the energy consumption and stimulate the lipolysis; and the three extracts, which are proportionally compounded, can obviously enhance the slimming effect and have a synergic action.

High Intensity Repetitious Training (HIRT) is an exercise regimen consisting of approximately three minutes of intense exercise that puts an exerciser at the end of the anaerobic energy transfer system and prevents the exerciser from entering the aerobic energy transfer system. The HIRT Program exercise regimen subjects the muscles to high frequency intense muscle contractions for approximately three minutes to the point that the lactic system reaches a maximum followed by a period of rest for at least one to two minutes to restore creatinine and remove some of the lactate acid out of the blood stream. The HIRT exercise regimen enhances the benefits of lactate accumulation, post-exercise insulin and growth hormone release with lipolysis or fat reduction.

The invention discloses a preparation method of astaxanthin and resveratrol-containing self-microemulsion particles. The preparation method comprises the following steps: at a temperature of 40-60 DEG C, carrying out mixed dissolving on a surfactant, caprylic/capric triglyceride and a co-emulsifier, so that a blank self-microemulsion is obtained; adding resveratrol and astaxanthin into the blank self-microemulsion, and uniformly stirring, so that an astaxanthin and resveratrol-containing self-microemulsion is obtained; adding hydroxypropyl methylcellulose into the astaxanthin and resveratrol-containing self-microemulsion, and uniformly stirring, so that a mixed suspended astaxanthin and resveratrol-containing self-microemulsion is obtained; and finally, adding microcrystalline cellulose, so that the astaxanthin and resveratrol-containing self-microemulsion is changed into solid granular powder, namely, astaxanthin and resveratrol-containing self-microemulsion particles. Through the way, the preparation method disclosed by the invention is simple, and no special high-energy-consumption production equipment is required in the process of preparation; obtained products effectively increase the solubility of astaxanthin and resveratrol in water, and improve the influence of stomach scattering and intestinal lipolysis; and the effective bioavailability is high.

The invention relates to healthcare food, in particular to healthcare vinegar containing resveratrol and capable of resisting oxidation, protecting heart and cerebral vessels and increasing immunity and a production method of the healthcare vinegar. The healthcare vinegar comprises a main material and auxiliary materials, wherein the weight ratio of the main material to the auxiliary materials is 1:5-10, the main material is sticky rice, millet or wheat, and the auxiliary materials comprise at least one of polygonum cuspidatum, grape skin, grape seed, peanut skin, peanut seedling and peanut root and rice husk, salt, sugar, yeast and solid fermentative substrate of vinegar. The healthcare vinegar and the production method thereof have the advantages that the resveratrol can be fully dissolved in the vinegar, the stomach dispersing and intestinal tract lipolysis of the resveratrol are increased effectively, and the resveratrol can be easily absorbed by human bodies as compared with resveratrol healthcare food; the healthcare vinegar is simple in production process, easy in raw material obtaining, low in cost, high in nutritional value, good in healthcare effect, capable of delaying aging and enhancing immunity and suitable for everyone.

The invention discloses a slimming nano-liposome and a preparation method thereof, and belongs to the technical field of special cosmetics. The slimming nano-liposome is prepared from the following components in parts by weight: 0.10 to 30.00 parts of a slimming functional component, 1.00 to 10.00 parts of phospholipid, 0.10 to 5.00 parts of sterol, 1.00 to 10.00 parts of an emulsifier, 2.00 to 30.00 parts of polyhydric alcohol and the balance of water, totaling 100 parts. By directly or indirectly promoting lipolysis, inhibiting adipocyte differentiation, inhibiting intake of free fatty acidin adipocytes and synthesis of triglyceride, skin microcirculation is promoted. Therefore, the number and the volume of fat cells are reduced, and the slimming functional component for inhibiting andeliminating fat accumulation is loaded in the nano-liposome with the particle size of 10-500nm. The slimming nano-liposome has the characteristics of good stability, high safety (without hormone), targeted slow release, synergistic interaction, good transdermal absorption, long residence time, high bioavailability and the like, and thus, has a relatively ideal slimming effect.

The invention discloses maca ferment and a preparation method thereof. The method specifically includes the steps of firstly, stirring and mixing maca mixed fermentation raw materials to obtain a mixture; secondly, adding an enzyme activity keeping agent to the mixture; thirdly, adding bacterial liquid, and conducting sealing and fermenting; fourthly, conducting filtering. The maca mixed fermentation raw materials include, by weight, 5-15 parts of maca, 10-30 parts of apple, 10-20 parts of carrot, 5-15 parts of broccoli, 20-40 parts of shiitake and 10-20 parts of cucumber. The maca ferment contains multi-enzyme ferment, proteolysis ferment, lipolysis ferment and amylolysis ferment, contains macaenes, macamides, various natural vitamins, mineral substances, amino acid, trace elements and the like, can be used for enhancing vigor, adjusting reproduction and metabolism, promoting fertility, improving the sexual function, treating climacteric syndromes, climacteric syndromes and depression, increasing bone mineral density, treating anemia and resisting oxidation, and is a natural internal secretion adjustor. In addition, the ferment has effects on resisting cancer and leukemia and the like.

Cosmetic methods for obtaining a slimming effect are disclosed. The methods include providing a composition containing a carob (Ceratonia siliqua L.) seed extract as a slimming agent and a physiologically acceptable medium, and topically applying the composition on at least a portion of the body or face. The topical application of the composition includes the application of an effective amount of the composition that increases the expression of aquaglyceroporins, promotes lipolysis, and/or reduces localized excess body fat.

Disclosed is a transdermal composition, which uses high-purity phosphatidylcholine that is most susceptible to oxidation and the like, and which exhibits high stability and high migration into the skin. Specifically, a transdermal composition having good stability and migration into the skin is able to be obtained by preparing a transdermal composition (a colloidal dispersion liquid of phosphatidylcholine) that contains high-purity phosphatidylcholine, carnitine, a polyhydric alcohol and water. Since the transdermal composition does not contain an oleaginous base (an oil component), the transdermal composition has skin compatibility and is thus useful as a therapeutic agent or a cosmetic preparation. In addition, phosphatidylcholine and carnitine have an effect of achieving good migration into the skin and are capable of promoting systemic or local lipid metabolism in subcutaneous adipose tissues. Consequently, the transdermal composition is able to provide a transdermal preparation that is capable of promoting lipolysis in subcutaneous adipose tissues.

The invention provides a traditional Chinese medicine composition used for burning fat and losing weight as well as a patch and a weight losing package thereof. The traditional Chinese medicine composition comprises the following ingredients in parts by weight: 28-32 parts of lotus leaves, 15-20 parts of polygonum multiflorum, 18-24 parts of safflowers, 16-25 parts of peach kernels, 18-23 parts of rhizoma alismatis, 27-31 parts of Chinese angelica, 15-20 parts of immature bitter orange and 18-24 parts of medicated leaven; the patch is prepared from the traditional Chinese medicine composition and auxiliary materials in a ratio of parts by weight of 1:(2-5); and the weight losing package comprises the patch and food, and the food is prepared from the following ingredients in parts by weight: 25-35 parts of gorgon fruits, 28-32 parts of konjak, 18-22 parts of lotus leaves, 25-30 parts of hawthorn and 15-25 parts of poria cocos. The traditional Chinese medicine composition provided by the invention has the advantages that in vivo lipolysis is effectively promoted, not only is in vivo metabolic cycle improved, but also lipolysis efficiency is improved, and fat accumulation is prevented, so that a function of losing weight is achieved.

The invention provides biological active peptide for promoting growth of a piglet. The biological active peptide comprises an amino acid sequence shown in SEQ IDNo.1, the absorption and utilization rate of nutrient substances in feed for the piglet can be obviously increased through the biological active peptide, growth and development of the piglet can be promoted, the morbidity can be reduced, and the survival rate of the piglet can be increased. Furthermore, the preparation method of the biological active peptide for promoting growth of the piglet and application of the biological active peptide to promoting growth of the piglet and reducing the death rate of the piglet are provided. The biological active peptide for promoting growth and development of the piglet is generated under the synergistic effect of multiple kinds of enzyme production probiotics and is applied to the piglet, constructive metabolism and lipolysis of the organism are promoted, protein synthesis is promoted, and the aims of promoting growth of the piglet and increasing the growth speed of the piglet are achieved. The function of promoting growth and development of the piglet is achieved by adjusting the hormone level of an endocrine system, the problem of hormone residues is solved, and the aim of healthy and environment-friendly breeding is achieved.

The invention relates to an application of bile acid to preparation of a metabolic disease drug. DCA (deoxycholic acid), GDCA (glycodeoxycholic acid) and TDCA (taurodeoxycholic acid) can increase basic metabolism rate by increasing the steatolysis and oxidation functions of white adipose tissues, in-vivo glycolipid metabolism is improved, intestinal flora are adjusted, high fat induced mouse obesity is relieved, and the application has great significance for clinically translational target spot search.

The invention discloses a lipolysis-accelerating slimming composition and a preparation method thereof. The lipolysis-accelerating slimming composition comprises concentrated whey protein, fruit juicepowder, crystalline fructose, skimmed milk powder, isolated soybean protein, resistant dextrin, inulin, pea protein, galactooligosaccharide, oat fiber, wheat fiber, conjugated linoleic acid, xylooligosaccharide, konjaku flour, cod collagen peptide, psyllium husk and medium chain triglyceride. The invention also provides a preparation method of the composition. The lipolysis-accelerating slimmingcomposition has the advantages that prepared from pure natural materials, the composition has no side effect after exposure, boiling and processing and avoids of discomforting a human body after beingtaken; the composition can effectively extract active ingredients from the raw materials after double-effect extraction by distilled water and alcohol, increase the utilization rate of the materials,effectively reduce the fat content of the human body and effectively promote lipolysis, and is high in satiety degree and nutrition, thereby achieving weight loss.

The invention discloses a fruit enzyme formula and a preparation method thereof. The fruit enzyme comprises the following raw materials: 8-15% of apples, 8-15% of snow pears, 15-25% of bananas, 5-15%of dragon fruit, 8-15% of papayas, and 25-35% of lemons. The preparation method of the fruit enzyme comprises the following steps: raw material treatment, fermentation and filtration, wherein the rawmaterial treatment comprises: raw material selection, and raw material pretreatment. The fruit enzyme is prepared by using a variety of fresh fruits such as apples, snow pears, bananas, dragon fruit,papayas and lemons as raw materials, contains various enzymes, lipolysis enzymes and proteolysis enzymes, and has the effect of slimming. The fruit enzyme causes the blood in the body to be weakly acidic after drinking, removes waste from the body, maintains bacterial balance in intestines, strengthens cells, promotes digestion, strengthens resistance, maintains balance in all aspects, and has theeffects of detoxifying and relaxing the bowels.