13 results about "Fat removal" patented technology

The invention relates to the technical field of biomedical materials and tissue engineering, and discloses a preparation method and application of adjustable porous fat foam. Comprising the following steps: fat tissue pretreatment and freeze-thaw circulation, multi-step combined decellularization and impurity removal, graded washing and purification, freeze grinding and freeze drying, preparation of a decellularized fat matrix suspension, porous foam scaffold forming and foam scaffold gradient rehydration. By adopting a multi-step combined decellularization and impurity removal process, residual lipid droplets in adipose tissues can be actively extruded out by mechanical squeezing assisted by isopropanol degreasing, a lipid wrapping phenomenon is broken, meanwhile, residual nucleic acid and adipose components can be thoroughly removed by virtue of a synergistic degradation effect of nuclease and lipase, the immunogenicity risk is reduced, and the immunogenicity of the adipose tissues is improved. All the steps have a synergistic effect under strict control of temperature, concentration and time parameters, so that the structural integrity of the extracellular matrix is ensured, the decellularization efficiency and thoroughness are improved, and the biological safety and biocompatibility of a final product are ensured.

The present invention relates to a molecular association of a bile acid or a bile salt and a composition containing the same, and more specifically, to a skin-permeable formulation of deoxycholic acid, a lipolytic pharmacological agent, which has been developed as an external preparation rather than a conventional injection, and which dramatically improves patient compliance.

The present disclosure relates to a fat removal surgery instrument. The present disclosure additionally arranges / provides a fiber support on a lipolytic fat suction passage of a waveguide tube, the fiber support being made of an insulating material and supporting an optical fiber in a restrained state while being fixed to the waveguide tube, such that the optical fiber is prevented from being deformed and coming into contact with the waveguide tube, and thus, even if various factors (e.g., weight, contact with human tissue, etc.) are applied to the optical fiber during a fat removal surgery, the optical fiber is guided to effectively avoid direct contact with the waveguide tube and thereby be damaged, while a series of deformations (e.g., a curved shape, etc.) are suppressed / controlled based on the strong restraint of the fiber support.

The invention provides a safe and efficient animal skin biological degreasing method. The method is characterized in that esterase or protease with weak affinity to collagen and elastin and strong affinity to fat cell membranes is selected for synergistic effect, on the basis of not excessively damaging collagen and elastin, the permeation efficiency of lipase in animal skin and the full contact efficiency of lipase and grease are improved, and the catalytic effect of lipase is improved. And then through the synergistic effect of multiple lipases-alkalis, the hydrolysis rate of the grease is increased, and hydrolysates are effectively removed, so that efficient degreasing is realized. Through the technology, the grease content of the animal grease can be reduced to 2% or below, a petroleum-based surfactant is not used, and good energy-saving and emission-reducing effects are achieved. The method has important guiding significance for developing animal skin processing biotechnology and complex enzyme preparations.

The present invention provides a novel method that can improve or maintain muscle quantity or muscle strength, and a novel method that can prevent obesity, or lower body fat percentage, or lower body fat quantity, or lower fat removal quantity. The proteoglycan used in the present invention is obtained by a method for producing the proteoglycan, comprising the steps of immersing a biological sample comprising the proteoglycan in an aqueous solution of a surfactant and collecting the solution after the immersion.

The invention provides a bent fat rubbing needle, which is particularly suitable for fat release and suction operation of a region with physiological curvature of a slender bag. The fat rubbing needle body is in the preset bent shape, the bending angle ranges from 10 degrees to 60 degrees, the fat rubbing needle body better fits the natural radian of the neck and the natural radian of the shoulder, and operation smoothness and the comfort level of a patient are improved. A plurality of micropores are formed in the side wall of the needle body and are connected with a negative pressure device to assist in releasing and sucking adipose tissues, so that the operation efficiency is improved. The front end blunt end structure can effectively prevent nerve and blood vessel from being damaged by puncture, and safety is enhanced. The fat rubbing needle is made of medical stainless steel or biocompatible materials, and different use requirements are met. The matched bent liposuction needle is matched with the angle of the liposuction needle to cooperatively complete fat removal. The separating grooves and the clamping grooves are formed in the instrument box, various tools are stored in a classified mode, and the taking efficiency in an operation is improved. The needle is not only suitable for the treatment of the drastic bag, but also can be expanded to be applied to other plastic surgeries needing to be operated along the body curve, and has a wide application prospect.

The application relates to the cleaning field and discloses a cleaning device of a fish skin degreasing equipment. In the application, the cleaning device of the fish skin degreasing equipment comprises an upper loading plate, the upper end of the upper loading plate is fixedly connected with a placing box, a plurality of rotating shaft plates are fixedly connected in the inside of the placing box, clamping belts are rotationally connected to the side surfaces of the rotating shaft plates, the clamping belts are clamped in clamping grooves arranged in a rectangular clamping groove plate, the position of a clamping plate in the rectangular clamping groove plate is fixed, the position of the clamping belt is ensured to be stable, the water spraying head assembly at the lower end is limited, the position of the water spraying head assembly is ensured to be stable, the rotating use of the clamping belt is facilitated by using the rotating shaft plates, the staff can conveniently control and use, the working position of the connecting spring is limited by the limiting plate, and the position stability between components is ensured.

The invention provides an acellular matrix for treating stress urinary incontinence as well as a preparation method and application of the acellular matrix. Splitting the soft tissue by using a cell lysis solution to remove cell debris; removing nucleic acid, degreasing and then micronizing; and adding the soft tissue particles and the soft tissue cross-linked particles into a phosphate buffer solution according to a ratio, mixing and emulsifying to obtain the acellular matrix for injection for treating stress urinary incontinence. The cell removal rate reaches 99%, the fat residue is less than 0.3%, and the injection is injected around the sphincter of the urethra (middle section or bladder neck) and / or in the urethra according to 0.5 ml / point and 3-4 points during clinical application to play roles in filling, connecting and repairing tissues, so that the damaged urethra supporting structure is repaired, the structural integrity and strength of connective tissues and the sphincter around the urethra are maintained, and the application prospect is wide. Therefore, the symptom of stress urinary incontinence is improved.

The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a medicinal and edible composition helpful for controlling in-vivo fat and a preparation method and application thereof. The medicinal and edible composition is prepared from the following raw materials in parts by weight: 10-50 parts of Chinese yam, 10-50 parts of phaseolus calcaratus, 10-50 parts of black rice, 10-50 parts of buckwheat, 10-30 parts of hawthorn, 20-50 parts of black sesame, 1-20 parts of tangerine pith, 1-20 parts of exocarpium benincasae, 20-50 parts of poria cocos and 10-40 parts of radix fici simplicissimae. The medicinal and edible composition obtained by the invention realizes fat removal and lipid reduction by regulating the functions of viscera, meets the demands of the market on mild fat reduction schemes, and is simple, convenient, low in cost and effective.

The invention relates to the technical field of immunofluorescent staining, in particular to an adipose tissue whole-tissue immunofluorescent staining method based on tabletting treatment. According to the method, tissue acquisition and fixation, tissue tabletting, membrane rupture and sealing, degreasing and autofluorescence removal, fluorescent staining, sheet sealing and imaging are sequentially carried out. According to the invention, a complete tabletting-degreasing-fluorescent staining integrated process is established, a set of systematic process which is standardized, high in repeatability and adaptive to conventional experimental conditions is provided, and tabletting whole tissue staining is realized in adipose tissues for the first time. The core of the invention lies in that the thickness of the tissue is reduced by a tabletting treatment means, and a set of optimized antibody permeation, sealing, degreasing and anti-autofluorescence treatment flow is matched, so that the immunofluorescent staining of the adipose tissue is effectively realized on the premise of not depending on complex tissue transparency and special imaging equipment, and the immunofluorescent staining effect is greatly improved. The method is especially suitable for detecting deep or low-abundance targets such as nerve markers.

This invention deals with alkoxylated polymers for oil and fat removal, their manufacture, their uses, particularly for use in cleaning compositions such as laundry detergent compositions, and specifically for improved clay removal and / or oily / fatty soil removal and / or body soil removal and / or whiteness maintenance in laundry care.

This invention provides a method for preparing a medical-grade high-transparency collagen solution, comprising the following steps: S1. Fresh animal tissue is taken, and after removing hair, fascia, fat, and flesh, it is sliced, washed to remove blood, washed with water, and freeze-pulverized; S2. The pulverized material is soaked in a mixed defatting agent for defatting; the mixed defatting agent includes a cationic surfactant and a lipase, wherein the cationic surfactant includes at least one of a bio-based surfactant and a quaternary ammonium salt surfactant; the bio-based surfactant includes at least one of rhamnolipid, sophorolipid, and trehalose; S3. The defatted material is frozen, irradiated, then soaked in purified water, filtered, and the swollen material is collected; S4. The swollen material is enzymatically hydrolyzed; S5. The filtrate after enzymatic hydrolysis is collected, salted out, filtered, and the residue is collected, then washed in a salt solution to obtain the salted-out material; S6. The salted-out material is dissolved in pure water, and the collagen protein mass fraction is controlled at 0.01-6.5%, then ultrafiltration is performed, the filtrate is collected, and stored at low temperature to obtain a collagen solution. The collagen prepared by this method has high transparency, and its structure remains intact during the preparation process, meaning the final collagen solution retains its complete triple helix structure. Furthermore, the entire extraction process does not involve the addition of heavy metals or toxic reagents, thus eliminating the risk of heavy metal or toxic reagent residues and broadening its application range.

The present invention relates to a detergent composition comprising a first lipase and a second lipase wherein the lipases have a synergistic effect on fat removal. In another aspect, the invention relates to the use of the detergent composition of the invention for cleaning textiles.