32 results about "Subcutaneous fatty tissue" patented technology

Exemplary embodiments of method and apparatus are provided for damaging and/or removing portions of subcutaneous fatty tissue while leaving the overlying dermal layer of the skin substantially undamaged. One or more hollow needles can be provided that include an arrangement within the lumen configured to retain or damage portions of fatty tissue that enter the lumen. Properties of the needle can be selected such that the needle can be inserted into skin and pass through the dermal layer, allowing fatty tissue to enter the distal portion of the lumen as it is advanced further, and then leaving the dermis undamaged when withdrawn. Such exemplary apparatus can include a plurality of such needles, a reciprocating arrangement to mechanically advance and withdraw the one or more needles, and/or a vibrating arrangement.

Exemplary embodiments of the present disclosure provide methods and apparatus for heating and removing subcutaneous fatty tissue using radiation. For example, an ablative laser or the like can be configured to generate a small hole in skin tissue that passes through the entire layer of dermal tissue. The hole size can be small, e.g., on less than about 1 mm or 0.5 mm in diameter. Continued application of the radiation can heat and/or vaporize subcutaneous fat proximal to the lower portion of the hole. Expansion of the heated or vaporized fatty tissue can facilitate ejection of the fatty tissue from the formed hole. The energy of a radiation pulse used to form a hole and heat the fatty tissue can be, e.g., greater than about 0.5 J, e.g., between about 0.5 J and about 35 J. The skin tissue can be cooled or partially frozen before forming one or more such holes therein, and a stabilizing film or plate may be adhered to the skin surface to help stabilize the ablated holes.

A method and device for stimulating human dermal tissue retraction and collagen and elastin production is provided. One or more lasers or other electromagnetic radiation devices produce at least two output beams (split or independent beams) that can be directed to deliver electromagnetic energy to a desired subsurface depth of dermal tissue, thereby disrupting the same, without causing excessive damage to the adjacent epidermis, subcutaneous fatty tissue, or blood vessels of the skin.

The present invention relates to a device for degreasing a full-thickness skin transplant, comprising a cutting unit, which is designed and arranged to separate a layer of subcutaneous fatty tissue located on the full-thickness skin transplant. The device comprises a drawing roller which is arranged across a gap at a distance from a cutting edge of the cutting unit, and which is designed to deliver the full-thickness skin transplant to the cutting unit by rotating the drawing roller.

The invention discloses a method for facilitating proliferation of adipose-derived stem cells. The method comprises the following steps: (1) taking a subcutaneous fatty tissue, washing the subcutaneous fatty tissue with a PBS buffer solution, removing an adipose tissue membrane and blood vessels and shearing off the subcutaneous fatty tissue into fragments with the sizes being 1 mm<3>, carrying out enzymic digestion, adding a complete medium after digestion is finished, centrifuging, removing supernatant, resuspending cell precipitates on the complete medium, inoculating the cell precipitatesin a culture bottle, changing a culture solution after culturing for 24 h and removing cells which are not attached to walls, then changing the solution every 3 days, digesting for 3-5 min with 0.25%of trypsin and 1 mmol/L EDTA at the temperature of 37 DEG C after cell fusion, stopping digestion of the complete medium, and carrying out passage at the ratio of 1: 2; and (2) inoculating passage cells into a culture bottle which contains the complete medium at the density of 1.5* 104/cm<2>, culturing for 48 h and then changing the culture medium into an incomplete medium, meanwhile adding a jatrophane type diterpenoid compound and continuing culturing for 24-72 h. Surface euphorbia helioscopia terpene A, surface euphorbia helioscopia terpene B and surface euphorbia helioscopia terpene F canbe used as an accelerant for proliferation of adipose-derived stem cells, and can be added in a DMEM medium to obtain an adipose-derived stem cell high-proliferation medium.

The invention discloses a culture method for inducing chondrogenic differentiation of adipose-derived stem cells and a culture solution. The culture method comprises the following steps: (1) taking asubcutaneous fatty tissue, washing the subcutaneous fatty tissue, removing an adipose tissue membrane and blood vessels and shearing the subcutaneous fatty tissue into broken blocks, carrying out enzymic digestion, adding a complete medium, centrifuging to remove adipose cells and lipid droplets, resuspending on the complete medium, inoculating into a culture bottle, culturing for 24 h and then changing the culture solution to remove cells which are not attached to walls, changing the solution every three days, digesting for 3-5 min with 0.25% of pancreatin and 1 mmol/L EDTA at the temperatureof 37 DEG C after cell fusion, stopping digestion of the complete medium, and carrying out passage at the ratio of 1: 2; and (2) inoculating passage cells into the culture bottle which contains the complete medium, culturing for 48h and then changing the medium into an incomplete medium, adding a Sox9 gene activator to continue culturing, and changing the medium every three days. By the providedmethod, chondrogenic differentiation of the adipose-derived stem cells can be induced effectively, the adipose-derived stem cells can be used as seed cells to prepare a large number of chondrocytes tomeet clinic requirements to the chondrocytes.

The invention discloses an natural rare bird feed addictive, which comprises the following raw materials by weight: 22-28 parts of anise powder, 22-28 parts of small fennel powder, 22-28 parts of pepper powder, 22-28 parts of clove powder, 8-11 parts of garlic powder, 22-28 parts of chili powder, 4-5 parts of honey, 22-28 parts of tea leaves powder, 22-28 parts of onion lyophilized powder, 8-11 parts of lotus leaf powder, 8-11 parts of canna root lyophilized powder, 8-11 parts of black bean powder, 2-4 parts of bitter gourd powder, 2-4 parts of elm leaf powder and 2-4 parts of Trichosanthes bark powder. According to the invention, the above raw materials are uniformly mixed to obtain the product. The addictive is added in the natural rare birds feed with the proportion of 1-2% for feeding the rare birds, the rare birds of an age of 50 days are fed by the feed with the addictive provided by the invention every day, thereby the fertility rate, survival rate and feed/egg ratio can be increased. According to the addictive of the invention, meat quality having special fragrance is formed during the growth process of the rare birds fed with the feed with the addictive, and the delicate fragrance after killing the rare birds can be still kept. Simultaneously, the subcutaneous fatty tissue of the rare birds can be obviously reduced, the meat quality can be enhanced, the dung of the rare birds has no stink, the morbidity is low, and the addictive provided by the invention is especially be beneficial to purifying environment of large-scale rare bird fields.

The invention discloses a feed additive for rare birds and animals, which comprises the following raw materials in parts by weight: 22-28 parts of anise powder, 22-28 parts of fennel powder, 22-28 parts of pepper powder, 22-28 parts of clove powder, 22-28 parts of garlic powder, 22-28 parts of chili powder, 4-5 parts of honey, 22-28 parts of seabuckthorn powder, 22-28 parts of freeze-dried powder of onion, 8-11 parts of lotus leaf powder, 8-11 parts of freeze-dried powder of canna, 8-11 parts of black soybean flour and 2-4 parts of balsam pear powder. The feed additive for rare birds and animals is prepared by mixing the raw materials uniformly. The feed additive is added into the feed for rare birds and animals of 50-day old according to the proportion of 1-2%. The fertilization rate and the survival rate of the rare birds and animals fed by the feed with the feed additive everyday can be improved obviously, and due to the adoption of the feed additive for rare birds and animals, the egg-feed rate can be improved. The meat of the rare birds and animals fed by the feed with the feed additive in the growing process has a peculiar flavor, and even the flavor still remains on the killed rare birds and animals. The subcutaneous adipose tissue of the rare birds and animals fed by the feed with the feed additive is reduced obviously, the quality of the meat is improved, the manure is not smelly, and the morbidity is low. The feed additive for rare birds and animals is particularly beneficial to purifying the large-scale farm for rare birds and animals.

The present invention relates to obesity related diseases, such as cancer of non-alcoholic fatty liver disease (NAFLD). Tissue perfusion is currently investigated by using dynamic contrast-enhanced magnetic resonance imaging which is an invasive technique and does not provide enough accuracy. As a result, the inventors worked on post-processing images of subcutaneous adipose tissue or the epididymal adipose tissue taken with a magnetic resonance imaging technique and a multifrequency magnetic resonance elastography technique to obtain parameters such as loss modulus and storage modulus which are more accurate for a diagnosing purpose. This post-processing method may be applied for a method for predicting that a subject is at risk of suffering from said disease, identifying a therapeutic target or a biomarker and screening compounds useful as medicine.

The present invention relates to human milk fortifiers comprising high protein content and long chain poly-unsaturated fatty acids. Use of such human milk fortifier improves the body adipose tissue distribution by increasing the subcutaneous adipose tissue mass, while at the same time not increasing visceral adipose tissue.

The invention discloses a preparing method of full-autologous tissue dual-layer envelope suitable breast prosthesis. Autologous skin epidermis layer and corium layer tissue and subcutaneous fatty tissue are taken from a patient according to the pre-estimated excision extension and mass, the epidermis layer tissue and skin-removed layer fatty tissue are placed in a sterile container, then the sterile container is placed in a water bath tank at 50-60 DEG C for warm bath for 20-40 min for deactivation, deactivated autologous fatty tissue is modified and sewn to form an object obtained in the suitable breast prosthesis with the required shape and size, the deactivated skin epidermis layer tissue is sewn to form an inner layer envelope sac for the object obtained in the suitable breast prosthesis according to the shape and size of the object obtained in the suitable breast prosthesis, and the corium layer is sewn to form an outer layer envelope sac for the object obtained in the suitable breast prosthesis. By means of the method, the immersion of inflammatory cells of surrounding tissue can be prevented after the prosthesis is implanted, the inflammatory reaction probably happening to the object contained in the prosthesis is prevented, the prosthesis is free of piercing and breaking risks, and the toughness, elasticity, appearance maintaining capacity and resistance capacity of squeezing and other external injuries of the prepared prosthesis are improved.

Prostacyclin (PGI2) analogues which are agonists of the prostacyclin receptor (PI) are demonstrated to activate lipolytic activity in adipocytes. Also described are pharmaceutical compositions and methods for using the PGI2 receptor agonists to reduce subcutaneous adipose tissue and to treat or reduce symptoms of obesity-related diseases or disorders such as diabetes mellitus, fatty liver disease and cardiovascular disease.

The invention discloses a condyloma acuminata animal model for photodynamic medicine screening and a building method of the condyloma acuminata animal model for photodynamic medicine screening. The building method includes the following steps: (1) fresh condyloma body tissues are sent to a laboratory, subcutaneous fatty tissues are thoroughly removed, and tissue blocks are manufactured, wherein the tissue blocks are measured through a steel ruler or a vernier caliper and are manufactured through a No.10 surgical knife blade, and the size of the tissue blocks ranges from 0.05 cm<3> to 0.1 cm<3>; (2) a male SCID mice which is four weeks old serves as a laboratory animal, and the single tissue blocks manufactured in the step (1) are plugged into a needle hole of an inoculating needle through tweezers so as to be inoculated under the skin of the back of the SCID mice; (3) the SCID mice inoculated in the step (2) is fed; and (4) the animal model fed in the step (3) is used for photodynamic medicine screening. The building method is short in laboratory time, high in HPV infection pathogenicity rate and low in modeling fatality rate; and the model can be applied to photodynamic treatment medicine screening for condyloma acuminate caused by human papilloma viruses.

Metal lower eyelid pocket reducer is round metal concave disk that is worn at night to reduce the size of lower eyelid pocket. The lower temperature will decrease blood circulation to the tissue and to atrophy it. Metal is a good heat conductor and radiator. When lower eyelid pocket is covered with a metal lower eyelid pocket reducer the temperature and blood supply of lower eyelid will decrease and the subcutaneous fatty tissue of lower eyelid will atrophy. This is a painless non-surgical cosmetic procedure.