78 results about "Triiodothyronine" patented technology

The invention provides a chemoluminescence immunoassay measuring kit and a preparation method thereof for quantificationally detect triiodothyronine (T3) magnetic particles. The kit mainly comprises a triiodothyronine serial calibration sample, magnetic particle solution coated by an anti-fluorescein isothiocyanate (FITC) monoclonal antibody, a T3 antigen marked by biotin, T3 monoclonal antibody marked by FITC, streptavidin marked by alkaline phosphatase, chemoluminescence substrate solution and 20-time concentrated washing solution. The invention adopts a competitive-method reaction mode, effectively utilizes the chemoluminescence technology combined with magnetic particles and biotin-avidin immunity magnifying technology principle to quantificationally detect the content of T3 in blood serum and blood plasma samples of human bodies and ensure the sensitivity of the detection. The kit is simple, convenient, fast, sensitive and stable to use, and provides a very valuable detection method for clinic diagnosis and scientific research works.

The invention relates to an auxiliary diagnostic kit of thyroid diseases, and discloses a tetraiodothyroxide test kit which comprises tetraiodothyroxide testing particles, tetraiodothyroxide resisting antibody marked by biotin and disintegrating agent; wherein triiodothyronine testing particles are luminous particles coated by diiodothyronine, and the disintegrating agent is 8-anilino-1- naphthalenesulfonic acid ammonium salt hydrate. The invention also discloses a use method of a triiodothyronine kit. The kit can be combined with other serum and clinical information for the auxiliary diagnosis of thyroid diseases and the monitoring of the treatment effect of relevant patients.

The invention relates to a fluorescent microsphere joint examination device for five analytes of thyroid and a preparation method thereof and belongs to the field of medical examination equipment. A sample pad, an immunofluorescence crosslinked antibody glass fiber membrane, a nitrocellulose membrane and an absorbing pad are bonded to a plastic board; two ends of the nitrocellulose membrane are inlap joint respectively with the absorbing pad and the immunofluorescence crosslinked antibody glass fiber membrane; the other end of the immunofluorescence crosslinked antibody glass fiber membrane is in lap joint with the sample pad; the nitrocellulose membrane is provided with a detection line T and a quality control line C; thyroxine antibody, thyronine antibody and hormothyrin antibody are marked on the detection line; goat anti-rat IgG polyclonal antibody is spotted on the quality control line C. The fluorescent microsphere joint examination device for five analytes of thyroid and the preparation method thereof have the advantages that thyroxine, thyronine and hormothyrin antibodies are applied to coat the nitrocellulose membrane, high specificity is achieved, T3 antibody, T4 antibody, TSH antibody, free T3 antibody and free T4 antibody can be simultaneously detected in a specimen, and the device herein is simple to operate and highly practical.

The invention provides implantable drug delivery devices comprising a core comprising a polymer (or polymer blend) and one or more drugs or pharmaceutical substances, and an outer shell comprising a polymer (or polymer blend) and one or more porogen materials. The invention reduces burst release of drug. Pharmaceuticals such as triiodothyronine (T3) or ropinirole can be delivered by the devices.

The invention relates to the field of cytobiology, and particularly relates to a sweat gland differential induction medium and applications thereof. The sweat gland differential induction medium is prepared by adding the following components into a low-sugar DMEM medium: based on the volume of the low-sugar DMEM medium, 8-15% by volume of fetal calf serum, 0.3-0.5mu g / ml of semi-hydrocortisone succinate, 10-100ng / ml of rh-KGF, 1-3nmol / ml of triiodothyronine, 10-100ng / ml of rh-EGF, and 0.05-0.2ml / ml of an insulin-transferrin-sodium selenite solution. The sweat gland differential induction medium is constructed by taking a recombinant human keratinocyte growth factor as a key regulation factor, constructing the finished product of the sweat gland differential induction medium, inducing the differentiation of human umbilical cord mesenchymal stem cells to sweat gland sample cells. By using the medium disclosed by the invention, the result is stable and reliable, and the sweat gland differential induction medium can be widely used for related studies and clinical application of differential induction of various MSCs to the sweat gland cells.

The invention provides a method for improving hair biology, e.g., hair growth. The method comprises administering to a subject a monoamine oxidase inhibitor and a vasodilator, a zinc salt of a carboxylic acid, a xanthine compound, pyrithione or a salt thereof, saponin, tritapene, crataegolic acid, celastrol, asiatic acid, an inhibitor of 5-alpha-reductase, 1,4-methyl-4-azasteroid, an androgen receptor antagonist, azelaic acid or a derivate thereof, cyclosporin, triiodothyronine, diazoxide, retinoic acid, a prostaglandin analog, aminexil, carnitine tartrate, apigenin, procapil, or adenosine, in an amount effective to achieve a desired effect. The invention further provides a method of reducing or delaying the appearance of an age-related skin imperfection. The method comprises administering to the subject a composition comprising an MAO inhibitor. A kit for improving hair growth also is provided.

The invention provides implantable drug delivery devices comprising a core comprising a polymer (or polymer blend) and one or more drugs or pharmaceutical substances, and an outer shell comprising a polymer (or polymer blend) and one or more porogen materials. The invention reduces burst release of drug. Pharmaceuticals such as triiodothyronine (T3) or ropinirole can be delivered by the devices.

The invention relates to a culture medium of amniotic fluid cells, which belongs to the field of biochemistry. The culture medium comprises the following components: basic medium, transferrin, sodium selenite, insulin, triiodothyronine, glucagons, basic fibroblast growth factor, hydrocortisone, testosterone, estradiol, progesterone and added antioxidant, wherein the antioxidant is a mixture of vitamin E and L-ascorbic acid; and the culture medium can be used in amniotic fluid cell culture after 4 to 15 volume percent of fetal calf serum is added in the culture medium, and a great amount of amniotic fluid cells which are at a division stage and meet the requirements of clinical diagnosis and scientific research can be obtained just within 7 to 8 days. The culture medium remarkably improves the culture effects of amniotic fluid cells and obviously increases cloning efficiency and cloning growth rate, reduces culture time, increases the success rate of cell culture, and fully plays the synergetic effects of vitamin E and L-ascorbic acid of different antioxidants.

The invention relates to an aminotic cell culture medium, which is prepared from a basic culture medium, and further is prepared from the following component: transferrin, sodium selenite, insulin, triiodothyronine, glucagon, progesterone, hydrocortisone, testosterone, estradiol, a basic fibroblast growth factor, vitamin E, vitamin C, antibiotic and fetal calf serum. The invention also relates toapplication of the aminotic cell culture medium in antenatal diagnosis of aminotic cell growth and an aminotic cell culture method. The aminotic cell culture medium provided by the invention has theadvantages of capability of promoting aminotic cell proliferation and excellent quality of the aminotic cell culture medium.