10 results about "Fat transplantation" patented technology

The invention relates to the field of medical auxiliary equipment, and discloses an auxiliary fat transplantation device for a scar area, the auxiliary fat transplantation device comprises a syringe, the inner wall of the syringe is slidably connected with a piston, the outer wall of the piston is fixedly connected with a push rod, and the outer wall of the syringe is provided with an adsorption assembly; the adsorption assembly comprises a vacuum cover, the vacuum cover is arranged on the outer wall of the injection barrel, the outer wall of the vacuum cover is fixedly connected with a fixing pipe, the inner wall of the fixing pipe is fixedly connected with a plurality of cross-shaped sealing blocks, the cross-shaped sealing blocks are attached to the outer wall of the injection barrel, and the outer wall of the vacuum cover is fixedly connected with a connecting ring; a first sealing ring is arranged on the lower surface of the connecting ring, and a vacuum adsorption hole is formed in the vacuum cover. By means of the negative pressure adsorption structure, a scar area to be treated is evenly pulled and lifted before operation, fiber bundles in a concave area are preliminarily released, a stable'safe cortex operation space 'is formed, and the entering depth of a needle head is easier to control.

The invention discloses a monitoring system for fat necrosis risk after fat transplantation, and belongs to the technical field of autologous fat transplantation. The fat necrosis risk monitoring system comprises an oxygen saturation detection device used for obtaining oxygen saturation information of a transplantation area and a contrast area; the temperature detection device is used for acquiring temperature information of the transplantation area and the contrast area; the pressure detection device is used for acquiring pressure information of the transplantation area and the contrast area; the data acquisition device is electrically connected to the oxygen saturation detection device, the temperature detection device and the pressure detection device and is used for acquiring information detected by the oxygen saturation detection device, the temperature detection device and the pressure detection device; and the upper computer is electrically connected to the data acquisition device and is used for acquiring the data acquired by the data acquisition device and processing the acquired data. According to the invention, the fat necrosis comprehensive risk coefficient of the transplantation area can be obtained, so that an accurate quantitative index is provided for evaluation and nursing work after fat transplantation.

The utility model discloses a fat filtering collector, and particularly relates to the technical field of fat filtering, the fat filtering collector sequentially comprises a filtering assembly, a waste liquid collecting assembly and a sterilizing assembly from top to bottom, the fat filtering collector is used for aseptically filtering fat, an auxiliary assembly used for improving the filtering efficiency is arranged on the outer side of the filtering assembly, and the filtering assembly comprises a filtering cylinder. A first bottom plate is fixed to the bottom of the inner wall of the filter cylinder, a filter screen for filtering fat is fixed to the inner wall of the filter cylinder, the waste liquid collecting assembly comprises a waste liquid cylinder, a top plate is fixed to the top end of the inner wall of the waste liquid cylinder, and a second bottom plate is fixed to the bottom of the inner wall of the waste liquid cylinder; and the sterilization assembly comprises a sterilization cylinder and an ultraviolet sterilization lamp fixed at the bottom end in the sterilization cylinder. The interior of the collector can be sterilized at any time in the whole fat filtering process, whole-process sterile filtering and storage of fat are achieved, the fat purity is improved, and therefore the survival rate and the effect after fat transplantation are improved.

A powder formulation for preserving tissue and organ function, and more particularly to shelf stable powder formulations that can be reconstituted at point of use, including during a fat grafting process, coronary artery bypass graft surgery, and peripheral bypass surgery, or other grafting / transplant surgery prior to or during the medical procedure to preserve the tissues / organs used in these procedures. The powder formulation includes a reducing agent; an antioxidant; a sugar; a nitric oxide substrate; a buffering agent; and physically acceptable salt. Also provided are a method of preparing an organ or tissue preservation solution by reconstituting the powder formulation, and a method of preserving tissue or an organ using same.

The invention discloses a precise liposuction needle with a force feedback function and a fat transplantation navigation system, and relates to the field of medical instruments. Comprising a liposuction needle and a fat transplantation navigation system which achieve data interaction in a wireless or wired communication mode. The liposuction needle is used for collecting liposuction depth, tissue pressure and image data in real time and transmitting the data to the navigation system, and the navigation system generates body surface projection navigation information based on the received data and dynamically regulates and controls liposuction parameters. By integrating a real-time pressure monitoring system, a liposuction depth feedback system, an image data acquisition system and a body surface projection navigation system, the operation safety is improved, the fat cell survival rate is optimized, and the operation precision and symmetry are improved.

The invention relates to the technical field of medical intelligent control, in particular to a fat transplantation survival rate optimized reinforcement learning injection path planning system, which comprises a near infrared spectrum detection device, a fat cell survival rate distribution diagram, an injection path planning module, an injection path planning module and a fat transplantation survival rate optimization module, the injection path planning module constructs a reinforcement learning reward function based on the survival rate distribution diagram, generates an optimized injection path, and sends the optimized injection path to the injection speed control module and the fat particle distribution simulation module, and the fat particle distribution simulation module simulates the fat particle migration process in the optimized injection path. And a prediction result is generated and sent to the injection speed control module, the injection speed control module generates an injection speed control instruction according to the optimized injection path and the prediction result, the injection speed control instruction is executed through the injection needle, the fat survival rate can be remarkably improved by the system from traditional 30-50% to 70-85%, and repeated operation requirements are reduced.

The application relates to the field of biological medicine, and particularly relates to a cold storage solution and application of a combined traditional Chinese medicine compound biological stent drug delivery system in eardrum repair. The cold storage solution comprises a basic solution and L-alanyl-L-glutamine; the basic solution comprises a STEEN solution. The cold storage solution can promote metabolism and synthesis of glutathione of fat grafts, regulate ROS mitochondrial oxidative stress, reduce cold storage damage of the fat grafts, and improve the cold storage quality of the fat grafts. Meanwhile, the application uses Shengji Yuhong collagen sponge which contains an important classical prescription for promoting repair, forms a functional biological material with supporting and pro-angiogenic effects, forms a linkage mode of "double-stage regulation before and after transplantation", closely combines the actual difficulties of cell damage of fat groups and reduction of repair success rate caused by long eardrum repair time in the clinic, explores a brand-new research mode for improving the eardrum repair scheme, and has far-reaching clinical significance.

This invention discloses a method for preparing high-viability fat grafts, comprising: aseptically transferring adipose tissue in a closed system while maintaining complete isolation from air during the transfer; performing multi-stage liquid washing on the adipose tissue, including an initial washing and a secondary washing, to remove blood components, tissue debris, and drug residues; subjecting the washed adipose tissue to gradient centrifugation, including an initial low-speed centrifugation and a secondary high-speed centrifugation, to achieve uniform separation of fat cells through a sieve; and collecting the centrifuged fat grafts to obtain a final product with high cell viability and a high proportion of concentrated stem cells. By combining multi-stage liquid washing with gradient centrifugation, efficient purification and uniform separation of fat cells are achieved, effectively reducing the risk of inflammation and removing harmful residues such as lidocaine, resulting in a final fat graft with a high proportion of stem cells and excellent biocompatibility, supporting regenerative medicine applications.

The invention discloses a method for constructing a prediction model for preventing capsule contracture after implant radiotherapy through fat transplantation, a machine learning model is trained by obtaining rat radiotherapy data of hemispherical prosthesis transplantation and surface fat injection treatment, a basic model is obtained, a machine learning algorithm can process massive multi-dimensional data, potential information can be mined, and the prediction model can be used for predicting capsule contracture. Constructing a prediction model basis of the scientific system; meanwhile, radiotherapy rat data and patient clinical data after the silica gel prosthesis is implanted are integrated, and a cross-species association rule is calculated based on a nuclear canonical correlation analysis model to adjust the basic model. According to the mode, multi-source data information is integrated, the scientificity and systematicness of the model are enhanced, and capsule contracture can be predicted more comprehensively and accurately; kernel canonical correlation analysis can process a non-linear relation, mine internal relation of cross-species data, and reasonably integrate animal experiment mandatory data into a model optimized based on patient data, so that the model gives consideration to mechanism understanding and clinical practice, and the accuracy and reliability of clinical application are improved.

A method of preparing a fat graft includes introducing fat tissue into an internal chamber of a vessel of a cell or tissue isolation, purification, and storage device through a first opening of the vessel. The method also includes introducing an amount of a wash solution effective to wash the fat graft or an amount of a cryoprotectant effective to cryopreserve the fat graft into the internal chamber of the vessel through a second opening of the vessel and mixing the fat tissue with the wash solution or the cryoprotectant. The method further includes either: when wash solution is introduced, centrifuging the device containing the fat graft to separate the fat graft from the wash solution and drawing the wash solution from the first end of the device; or, when cryoprotectant is introduced, cooling the fat graft to a temperature below 0° C.