The invention relates to the technical field of Chinese medicament health products, in particular to a capsule with an effect of relieving physical fatigue. To solve the problems of long onset period and expensive price in the prior art, the invention provides a solution scheme that the capsule with the effect of relieving physical fatigue comprises the following raw materials in percentage by weight: 20 to 40 percent of ginkgo extract, 15 to 30 percent of American ginseng extract, 5 to 15 percent of medlar extract, 5 to 15 percent of radix astragali extract, 5 to 15 percent of Indian buead extract, and the balance of auxiliary materials. In the capsule, the traditional Chinese medicaments such as ginkgo, medlar, radix astragali, Indian buead and the like are mixed together with American ginseng to balance organ functions and nutrition, so the capsule obviously improves the anti-fatigue effect, and simultaneously has the advantages of quick response, reasonable price and simple preparation process.