64 results about "Polyuria" patented technology

This invention provides compounds which are represented by a general formula [I][in which X stands for hydrogen or halogen; B stands for halogen, cyano or optionally fluorine-substituted lower alkyl; D stands for a 3–10 membered aliphatic nitrogen-containing heterocyclic group; R3, R4 and R5 may be same or different, and each stands for hydrogen, lower alkyl optionally having substituent group(s) and the like; and a is 0 or 1]. These compounds exhibit high affinity to nociceptin receptors and whereby inhibit actions of nociceptin, and are useful as an analgesic, antiobestic, agent for ameliorating brain function, treating agents for Alzheimer's disease and dementia, and therapeutic agents for schizophrenia, neurodegenerative diseases, depression, diabetes insipidus, polyuria, hypotension and the like.

A traditional Chinese medicinal preparation for treating middle and old aged male diseases caused by kidney vacuity and a preparation method thereof. The traditional Chinese medicinal preparation is made from the following raw materials of: by weight, 10-40 parts of jujube, 10-40 parts of sharpleaf galangal fruit, 10-40 parts of raspberry, 10-40 parts of wolfberry, 10-40 parts of Chinese yam, 10-40 parts of polygonatum rhizome, 5-40 parts of Gorgon fruit and 5-40 parts of orange peel. The preparation provided by the invention has functions of nourishing liver and kidney, arresting polyuria, improving yang deficiency, nourishing liver and kidney yin, adjusting insufficiency of body fluid, nourishing and invigorating spleen, enriching blood, reinforcing the kidney and controlling noctural emission, invigorating spleen and stopping diarrhea, nourishing yin and yang and reinforcing liver and kidney, and has a good curative effect of treating middle and old aged male common symptoms such as body tiredness and hypodynamia, overfrequent nocturia, impotence, premature ejaculation and the like. The raw medicines of the preparation provided by the invention are all vegetation edible and medicinal materials with no toxic and side effect. The preparation provided by the invention has advantages of good taste and strong patient compliance, and is applicable to be taken for a long time.

The invention relates to a pendimethalin micro-capsule suspending agent and a preparation method thereof. The pendimethalin is taken as the micro-capsule core of the pendimethalin micro-capsule suspending agent and the content thereof is 10-450g / L; polyuria or polyurethane is taken as a micro-capsule wall of the pendimethalin micro-capsule suspending agent and the content thereof is 20-100g / L; the pendimethalin micro-capsule suspending agent also contains 20-100g / L emulsifier, 20-60g / L dispersing agent, 30-100g / L antifreezing agent, 1-10g / L viscosity modifier and 2-15g / L antifoaming agents and the balance of water. The pendimethalin micro-capsule suspending agent can solve the problem that the liquid preparation is easy to color and pollute the drug applying equipment; the agent does not contain the solvent and is environment-friendly; the compound of dispersing agent and emulsifier adopted by the invention can solve the problem of system creaming caused by coarse crystal easily generated by the low melting point compound following the temperature fluctuation; according to the preparation method provided by the invention, the temperature control is adopted, the operation is performed under normal pressure, no catalyst is used, the process is simple, no special equipment is required and the cost is low.

The invention discloses a cactus strawberry purple rice jam. The jam is prepared from the following raw materials in parts by weight: 110-130 parts of edible cactus, 136-150 parts of strawberries, 78-85 parts of purple rice, 13-16 parts of malus prunifolia, 6-9 parts of phyllanthus emblica, 4-6 parts of stir-baked semen plantaginis, 5-7 parts of astragalus complanatus, 6-8 parts of viola diffusa ging, 4-5 parts of morinda officinalis, 3-4 parts of rhizoma curculiginis, 44-53 parts of white granulated sugar, 18-24 parts of ground coffee, 5-8 parts of dark green tea powder, 10-12 parts of olive oil, 25-31 parts of Chinese date honey, and appropriate amount of purified water. The purple rice flour with a health care effect is added in the preparation process of the jam disclosed by the invention; the viola diffusa ging can clear away heat and toxic material, and cool blood and stop bleeding; the astragalus complanatus can warm and benefit the liver and the kidney, control nocturnal emission, arrest polyuria and improve eyesight; the phyllanthus emblica can clear away heat, cool blood, improve digestion, invigorate stomach, promote the secretion of saliva or body fluid, and relieve cough; the stir-baked semen plantaginis can excrete dampness, stop diarrhea, eliminate sputum and relieve cough; the morinda officinalis can reinforce the kidney, support yang, dispel wind, eliminate dampness, and strengthen tendons and bones; and the jam is bright and beautiful in color, moderate in sweet and sour, delicate and soft in taste, and high in nutrition and health care value, and has unique fruit aroma and purple rice aroma and wide market prospect.

A composition including an aliquot of the herb Herba Epimedii; and an aliquot of at least three supplemental herbs selected from the group consisting of Fructus Rosae Laevigatae; Fructus Rubi; Fructus Psoralea; Radix Morindae Officinalis; Fructus Schisandrac Chinensis; Fructus Ligustri Lucidi; Semen Cuscutae; and Radix Astragali. A composition including icariin; ursolic acid; ellagic acid; psoralen; deoxyschizandrin; oleanolic acid; quercetin; aslvagaloside; and an extract of the herb Radix Morindae Officinalis. Methods including administering a composition directed at treatment of various kidney disorders or the promotion of kidney health and to the overall health of the kidney, including the use of a composition in the treatment of prostate cancer, prophylatic prostate health, reduction of polyuria, incontinence, proteinuria, as well as for sexual satisfaction.

A composition including an aliquot of the herb Herba Epimedii; and an aliquot of at least three supplemental herbs selected from the group consisting of Fructus Rosae Laevigatae; Fructus Rubi; Fructus Psoralea; Radix Morindae Officinalis; Fructus Schisandrac Chinensis; Fructus Ligustri Lucidi; Semen Cuscutae; and Radix Astragali. A composition including icariin; ursolic acid; ellagic acid; psoralen; deoxyschizandrin; oleanolic acid; quercetin; aslvagaloside; and an extract of the herb Radix Morindae Officinalis. Methods including administering a composition directed at treatment of various kidney disorders or the promotion of kidney health and to the overall health of the kidney, including the use of a composition in the treatment of prostate cancer, prophylatic prostate health, reduction of polyuria, incontinence, proteinuria, as well as for sexual satisfaction.

The present invention discloses a traditional Chinese medicine formula Guiyuantangkang for the treatment of diabetes and the complications, the present invention takes membranous milkvetch root, common anemarrhena rhizome, swordlike atractylodes rhizome, raw common yam rhizome, kudzuvine root, Mongolian snakegourd root, stir-fried largehead atractylodes rhizome etc. as the raw materials. The present invention can not only effectively treat the hypertension, vascular diseases, renal damages, repeated infections, heart diseases and other various complications caused by diabetes, prevent the occurrence of the complications, but also can control the symptoms of the diabetes such as thirsty, starvation, emaciation and polyuria, stabilize the blood glucose fluctuations and tolerance caused by the western medicines for lowering blood glucose and effectively improve the quality of life of the patients with various diabetes without the diet control.

The invention provides an umbilical region dropping liquid for diabetic patients. The umbilical region dropping liquid is mainly composed of the following traditional Chinese medicines in parts: 1 part of snakegourd root, 1 part of unprocessed rehmannia root, 1 part of ginseng, 1 part of milkvetch root, 1 part of winged euony twigs, 1 part of dendrobium officinale, 1 part of danshen root, 1 part of resina draconis, and the like. The umbilical region dropping liquid has the effects of nourishing yin and tonifying yang, strengthening pancreas and tonifying spleen, and circulating sanjiao. The product not only reduces the blood glucose level, but also obviously improves complications such as dim eyesight, easy hunger sensation, and polyuria. The dropping liquid is directly dripped at the navel without being adhered by an adhesive tape, so that the allergy of the human body caused by adhesion is avoided. The medicament is rapidly absorbed within 5 minutes, an absorption rate is higher, andthe effect is better.

The invention provides an application of alpha-mangostin for prevention and treatment of diabetes mellitus. Alpha-mangostin can be used for decreasing blood glucose of diabetics, increasing glucose tolerance and improving symptoms of polydipsia, polyuria, polyphagia, emaciation and thirsty of the diabetics, can also be used for lowering high-fat-diet-induced obesity mouse total cholesterol content, has a cholesterol lowering effect, is capable of improving abnormality of the high-fat-diet-induced mouse glucose tolerance, and has functions of preventing and delaying obese patients from getting diabetes mellitus.

The invention relates to a medical preparation, in particular to a medicamentt for treating enuresis, which is characterized by being prepared from the following active pharmaceutical ingredients in parts by weight: 5-7 parts of fructus alpiniae oxyphyllae, 5-7 parts of radix linderae, 3.5-5.5 parts of cherokee rose and 2-4 parts of yam. The medicament can be prepared into pills, granules, capsules or tablets, has the effects of warming a kidney, dispersing cold, arresting polyuria, stopping enuresis and restraining intestine to stop darrhea, mainly treats the enuresis caused by kidney-qi deficiency with the manifestations of incessant enuresis, copious and clear urine or urine dripping, flabby tongue and forceless deep pulse and also treats chronic darrhea and protracted dysentery.

The invention relates to a Chinese traditional medicament composition for curing diabetes and process for preparation, wherein the efficacy composition contained in the Chinese traditional medicament composition is that the invention chooses radix rehmanniae, cortex mori, coptis, liriope, mulberry leaves, kudzu root, kadsura, salvia, americanwater plantain, astragalus or barrenwort. The Chinese traditional medicament composition of the invention can nourish yin, clear heat, supplement qi and activate blood, applicable to the assistant treatment of yin deficiency and heat hyperactivity syndrome and blood-stasis diabetes. The invention can improve the symptoms of thirst, polydipsia, hyperphagia, polyuria, marasmus and irascibility, limb numbness, and the like, and especially has good effect to the yin deficiency and heat hyperactivity syndrome and blood-stasis diabetes. The invention doesn't have obvious side effect.

The invention relates to an application of an artemisinin derivative to preparation of a medicine for preventing and treating 2-type diabetes mellitus and complications of the 2-type diabetes mellitusand a medicine composition containing the artemisinin derivative. According to the application, experiments confirm that the artemisinin derivative such as artemether can increase the respiration quotient of the 2-type diabetes mellitus, oxidation of metabolic substrate glucose is facilitated, blood glucose of the 2-type diabetes mellitus is reduced, polydipsia and polyuria symptoms are improved,and urinary albumin excretion is decreased. The artemisinin derivative has an obvious protection effect on the 2-type diabetes mellitus and the complications thereof.

The invention discloses a pure Chinese medicinal preparation for treating infantile enuresis, and a preparation method thereof. The preparation consists of the following raw medicinal materials in portion by weight: 20 to 60 portions of dogwood, 10 to 40 portions of sharpleaf galangal fruits (fried with salt), 10 to 40 portions of malaytea scurfpea fruits, 10 to 40 portions of astragalus roots (baked with honey), 10 to 30 portions of codonopsis pilosula, 10 to 30 portions of Chinese yams, 10 to 30 portions of eucommia bark, 10 to 30 portions of shizandra, 10 to 30 portions of achyranthes roots, 10 to 30 portions of medlar, 10 to 30 portions of rhizoma atractylodis macrocephalae, 5 to 15 portions of liquorice (baked with honey). The preparation has the efficacies of replenishing middle-Jiao and Qi, invigorating spleen and stomach, warming kidney, dispelling cold, and controlling seminal emission and polyuria, is clinically used for treating the infantile enuresis, and has the advantages of exact therapeutic effects, safety and no toxicity.

The invention relates to the use of isoform-specific fructokinase (ketohexokinase) (KHK) inhibitors alone or in combination with various agents to both prevent and treat a wide variety of diseases including, but not limited to, sugar craving, obesity, features of metabolic syndrome (including insulin resistance, hypertriglyceridemia, hypertension, and fatty liver), polyuria, proximal tubular injury, and diabetic kidney disease.

The invention discloses a single-component polyuria preventive coating for an agricultural irrigation concrete drainage channel and a water duct. The single-component polyuria preventive coating comprises the following raw materials in parts by weight: 20-70 parts of isocyanate, 50-85 parts of polyether polyol, 4-24 parts of a hindered amine compound, 15-40 parts of a solvent, 10-40 parts of packing, 2-5 parts of auxiliaries, 1-3 parts of pigments, and 1-3 parts of a catalyst. In the synthesis of the single-component polyuria preventive coating, the hindered amine compound is added, so that urea radicals are introduced into the components, the polarity of the component is increased, the attraction of hard segments of the material can be increased, the material is more compact, and the oil resistance, medium resistance and microorganism resistance of the material can be improved. In addition, the mechanical property of single-component polyuria is far higher than the conventional single-component polyurethane.

The invention relates to the technical field of deep processing of agricultural products, in particular to a method for preparing Vaccinium spp. anthocyanin and a product of the method. The Vacciniumspp. Anthocyanin can be used for improving polydipsia and polyuria of diabetic patients. The method comprises the steps: adopting Vaccinium ashei as a raw material, extracting Vaccinium spp. anthocyanin by using a food-grade acidic ethanol solution, purifying the obtained Vaccinium spp. anthocyanin by using AB-8 macroporous resin column chromatography, performing elution so as to remove pectin, protein and other impurities by using distilled water, performing elution on the adsorbed Vaccinium spp. anthocyanin by using a food-grade ethanol solution. It is determined that the purity of the Vaccinium spp. anthocyanin prepared by using the method can reach 76% or above, and through gavage of diabetic mice, the symptoms of polydipsia and polyuria and related indexes to glucose and lipid metabolism of the mice can be improved effectively; and the method has low cost, high efficiency, safety and reliability, is suitable for mass production, and has good industrial prospects.

The invention relates to health care beverage which is suitable to be drunk by diabetes patients, which is characterized by consisting of Chinese yam, radix scutellariae, medlar, edible lotus seeds, sticky rice, pawpaw, pumpkin, xylitol, protein candy and so on. The health care beverage selects a plurality of Chinese herbal medicines, changes decoction into beverage which has refreshed mouthfeel and is easy to be accepted by patients, not only can relieve the pain of polydipsia, polydipsia and polyuria of the patients but also can achieve the efficacies of getting rid of illness and strengthening the body.

The invention relates to an application of tea to preparation of medicines for relieving polyuria symptoms caused by diabetes, and discloses the tea which can quickly, strongly and durably improve thepolyuria symptoms of patients suffering from diabetes. The mechanism of the application lies in that the tea can notably increase the expression amount of kidney protein kinase C, aquaporin or urea transport protein of the patients suffering from polyuria, and can promote the membrane shift of the kidney protein kinase C, the aquaporin or the urea transport protein, so that the reabsorption capacity of kidney to water is reinforced, the micturition is reduced, and the blood sugar is reduced. The invention provides a new policy for effective improvement of the polyuria symptoms of the patientssuffering from diabetes, and reducing blood sugar.

The invention provides a polyuria-based elastomer material for protection and seepage prevention of concrete of a hydraulic building and a preparation method of the polyuria-based elastomer material.The polyuria-based elastomer material is prepared from a polyuria-based component A and a polyuria-based component B in the volume ratio being 1:1 through a reaction. The polyuria-based elastomer material has high binding force with the concrete surface, has good elasticity, impact resistance, wear resistance and chemical corrosion resistance, can adapt to moisture and low-temperature constructionenvironment and the use environment of long-time water soaking and high-speed water flow scouring and has the characteristics of being free from softening or shedding, corrosion-resistant, impact-resistant, wear-resistant, resistant to frost thawing, green, environmentally friendly and the like after being applied to the concrete surface of hydraulic buildings (including dams, water delivery tunnels, box culverts, channels and pipelines).

The present invention discloses a spine date jasmine beverage and a preparation method thereof. The spine date jasmine beverage comprises the following raw materials by weight: 19-22 parts of palm oil, 18-20 parts of lucid ganoderma, 18-20 parts of agrocybe aegirit, 15-18 parts of esculente umbilicaria, 10-12 parts of spine date seed powder, 9-11 parts of jasmine essence, 8-9 parts of cabbage juice, 7-8 parts of cabbage, 9-10 parts of grilled chicken wings, 10-11 parts of grilled ham, 4-5 parts of allspice, 6-7 parts of Diospyros kaki L. f. constricta, 4- 5 parts of common baphicacanthus rhizome and root, 3-4 parts of sweetened green bean paste, 7-8 parts of chocolate, 0.5-1 part of cirsium japonicum, 0.5-1 part of malt, 0.5-1 part of licorice root, 0.5-1 part of psoralea corylifolia, 0.5-1 part of fructus perillae leaves, 15-20 parts of nutritional additives and the balance of water. The present invention uses spine date seed powder which has efficacy of pacifying liver and regulating qi, moistening lung to nourish yin, warming spleen-stomach and eliminating dampness, astringing qi and arresting sweating. The spine date jasmine beverage has diverse tastes, rich nutrition and a low price. The added traditional Chinese medicine has efficacy of reinforcing kidney and strengthening yang, treating spermatorrhea and arresting polyuria, warming spleen and checking diarrhea, and promoting inspiration to relieve asthma.

The invention discloses an artemisia apiacea hance health rice crust. According to the present invention, artemisia apiacea hance leaf being rich in a variety of vitamins and having effects of heat clearing, detoxicating, spleen refreshing and appetite increasing, Chinese wolfberry leaf containing a variety of trace elements and having effect of immunity promoting, blood pressure reducing and liver protection, dodder containing a variety of amino acids and having effects of liver and kidney invigorating, essence strengthening, polyuria arresting and cardiovascular function regulating, radix polygoni multiflori being rich in starch and radix polygoni multiflori polysaccharides and having effects of dryness-syndrome moisturizing, health, diabetes prevention and treatment and the like, and the like are added to rice, and baking and other processes are performed to prepare the artemisia apiacea hance health rice crust, wherein the finished product artemisia apiacea hance health rice crust has characteristics of flat block, uniform slight green color, natural artemisia apiacea hance aroma and crisp and refreshing taste, is suitable for all ages, and has health effects of liver and kidney benefiting, spleen refreshing, appetite increasing, intestine smoothing and constipation relieving.

The invention relates to a method for preparing micro-sized monodisperse polyuria microspheres. The method comprises the following steps of: adding a mixed solvent of water and acetone and a diisocyanate compound monomer to a reaction flask at room temperature, wherein the weight ratio of the water to the acetone is 2 / 8-6 / 4, and the diisocyanate compound monomer accounts for 0.5-10.0 percent of the total weight of a mixed system; hermetically shaking up; putting in a constant-temperature water-bath vibrator; performing a polymerization reaction under the conditions that the vibration frequency is 70-150 times per minute and the temperature is 20-80 DEG C; and performing centrifugal separation and drying on a product after polymerization is ended to obtain the micro-sized monodisperse polyuria microspheres. According to the method for preparing the micro-sized monodisperse polyuria microspheres, precipitation polymerization is performed under the vibration condition by using only one monomer, thereby, the process is simple, the raw materials are single, the consumed reaction time is short, the monomer can be completely converted, and the yield of the microspheres can reach at least 86 percent. All the microspheres are clean in surface and contain a large amount of amido and can be used for the field of protein adsorption and separation, enzyme immobilization and chromatographic analysis.

The present invention provides a diagnostic method comprising continuously monitoring and transmitting urine output and urine flow rates of a catheterized patient to means which correlate the same with at least one of renal perfusion, renal function, fluid status, polyuria, oleguria, hypoperfusion, hemorrhage shock and GFR.

The present invention relates to a screening method for determining whether a substance of interest is a substance which alters GPR40-mediated cell stimulating activities, comprising using a substance of interest, a biomembrane containing GPR40, or cells containing said biomembrane, and phospholipase or salts thereof. According to the present invention, substances involved in insulin secretion can be screened. In addition, according to the present invention, substance useful for the prevention or treatment of diabetes, diabetic complications and degenerative diseases, hyperglycemia, polyuria, ketonemia, acidosis, insulin resistance, impaired glucose tolerance, neurodegenerative diseases, insulinoma, cancers, hyperinsulinemia, hyperglyceridemia, fatty liver, hypoglycemia due to insulin hypersecretion, arteriosclerosis, hyperlipidemia, cerebral stroke, obesity, various diseases induced by diabetes or obesity, and the like.

The present invention discloses a traditional Chinese medicine preparation for treating diabetic nephropathy, which is prepared from rhubarb polysaccharides, the total flavone of scutellaria root, total alkaloids of rhizoma coptis, and pharmaceutically acceptable auxiliary materials. Pharmacodynamic trials proved that the present invention has the effects of decreasing the blood glucose of the normal mouse, reducing the area under blood glucose concentration curve, and improving the sugar tolerance of the mouse; the present invention can improve the multi-food, the will drink, and the polyuriasymptoms of diabetic nephropathy model rats, reduce urinary protein and urinary albumin, decrease glycosylated hemoglobin, serum cholesterol and serum triglyceride, decrease overhigh creatinine clearance rate, reducing the renal index, alleviate the renal lesion, and have the effect for antagonizing early diabetic nephropathy. In addition, the present invention also discloses a preparation methodof the traditional Chinese medicine preparation and application in preparing a medicament for preventing and controlling diabetic nephropathy.

The invention discloses a Chinese herbal medicine capable of warming the spleen and kidneys. The Chinese herbal medicine is prepared from the following components in parts by weight: 8-12 parts of fructus alpiniae oxyphyllae, 13-17 parts of cloves, 10-14 parts of medicine terminalia fruits, 5-9 parts of fennels, 7-11 parts of combined spicebush roots, 14-18 parts of Chinese yams, 9-13 parts of dried gingers, 16-20 parts of raspberry fruits and 21-25 parts of bighead atractylodes rhizomes. The product is prepared from pure natural animals and plants, is green, has no pollution and has no side effect when being used; and the Chinese herbal medicine has the effects of warming the spleen, stopping diarrhea and saliva, warming the kidneys, arresting polyuria and securing essence.

Disclosed is a Chinese medicinal pill for treating polyuria and its preparation, wherein the medicinal pill is prepared from the following raw materials (by weight portion): chicken's gizzard-skin 160-180g, ootheca rubra 70-80g.