25 results about "Psoralea" patented technology

The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for relaxing muscles, stimulating blood circulation and dredging collaterals and a preparation method and application thereof. Comprising the following raw materials in parts by weight: 10-18 parts of angelica sinensis, 22-30 parts of ligusticum wallichii, 10-18 parts of safflower carthamus, 10-18 parts of peach kernel, 10-18 parts of radix achyranthis bidentatae, 22-30 parts of earthworm, 10-18 parts of cassia twig and 22-30 parts of fructus psoraleae. Through the synergistic effect of the angelica sinensis, the ligusticum wallichii, the safflower, the peach kernel, the radix achyranthis bidentatae, the earthworm, the cassia twig and the fructus psoraleae, the traditional Chinese medicine has the effects of promoting blood circulation to remove blood stasis, relaxing tendons and dredging collaterals, dispelling wind and eliminating dampness, and relieving swelling and pain; modern pharmacological studies show that the prescription can improve local microcirculation, inhibit release of inflammatory factors, regulate immune response and promote repair of damaged tissues, so that the treatment targets of relieving pain and recovering functions are achieved.

The invention discloses a traditional Chinese medicine composition for preventing and treating insomnia due to yang deficiency. The traditional Chinese medicine composition is mainly prepared from prepared rehmannia root, semen cuscutae, fructus psoraleae, radix aconiti carmichaeli, wine-processed radix bupleuri, rhizoma cimicifugae, cassia twig, herba taxilli, herba cistanche, pericarpium citri reticulatae, radix acanthopanacis senticosi and the like according to a certain weight ratio. The traditional Chinese medicine can be prepared into any common oral dosage form. The whole formula has the effects of warming kidney to strengthen yang, boosting essence and filling marrow, raising yang and transforming qi, warming channel and strengthening spleen, regulating qi and Chong, nourishing heart and tranquilizing mind, and has an exact curative effect of preventing and treating insomnia due to yang deficiency.

The application belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating lung cancer bone metastasis and application thereof. The main active ingredients of the traditional Chinese medicine composition include, in mass parts, 20-40 parts of radix codonopsis, 20-40 parts of poria, 20-40 parts of astragalus, 10-30 parts of atractylodes, 10-20 parts of licorice, 10-30 parts of curcuma, 10-20 parts of pinellia, 5-10 parts of dried tangerine or orange peel, 20-40 parts of oldenlandia, 10-30 parts of psoralea, 10-30 parts of drynaria, 10-30 parts of epimedium, and 10-20 parts of jackinthepulp. Animal experiments show that the traditional Chinese medicine composition can not only inhibit primary tumor growth, but also slow down tumor progression of bone metastasis. When combined with a chemotherapy drug, the traditional Chinese medicine composition can not only significantly enhance the tumor inhibition effect of the chemotherapy drug, but also significantly prolong the survival time of mice, relieve weight loss and organ toxic side effects caused by the chemotherapy drug.

The application relates to the field of medicines, and discloses a medicine combination for preventing and treating osteoporosis syndrome and a preparation method, wherein the medicine combination is made of tortoise shell, deer horn, psoralea, drynaria and rhizoma curculiginis. A stepwise liquid-phase assisted co-grinding technology is adopted, that is, psoralen extract, deer horn coarse powder and part of tortoise shell coarse powder are ground at low temperature of 0-5 DEG C, psoralen is locked in an amorphous solid dispersion state by using the keratin network of the deer horn; then the remaining tortoise shell coarse powder and drynaria-rhizoma curculiginis water extraction thick paste are added and ground at normal temperature, so that in-situ complexation reaction of plant organic acid and tortoise shell calcium carbonate is caused. The original components in the prescription are used as natural carriers and complexing agents, and the amorphous state of the difficult-to-dissolve components and the organic modification of inorganic calcium are realized without adding synthetic auxiliary materials. The medicine combination significantly improves the dissolution rate of psoralen and the calcium release amount in a neutral environment, and has excellent osteogenic activity.

This invention relates to the field of traditional Chinese medicine technology, and in particular to a traditional Chinese medicine composition for treating heel pain and its method of use. It is composed of the following ingredients: tortoise shell, wolfberry, drynaria, psoralea, cistanche, achyranthes, epimedium, eucommia, astragalus, yam, prepared rehmannia, angelica, salvia miltiorrhiza, calcined dragon bone, calcined oyster shell, prepared licorice, codonopsis, and atractylodes macrocephala. The method of use involves a combined internal and external therapy: internally, a concentrated decoction is taken morning and evening; externally, the dregs are decocted again and used for foot baths. This invention, through the principles of "tonifying the liver and kidneys, strengthening tendons and bones, promoting blood circulation and removing blood stasis, and nourishing the spleen and controlling water," combined with the internal and external treatment approach, solves the technical problems of existing heel pain treatments, such as significant side effects, short-lasting efficacy, and limited therapeutic dimensions. Clinical trials have verified that this invention can significantly reduce patients' VAS pain scores and improve their AOFAS ankle-hindfoot scores, with high safety and no obvious toxic side effects, showing good prospects for clinical application and industrial promotion.

The application provides application of psoralen in activating NK cells. The psoralen provided by the application is a coumarin component extracted from traditional Chinese medicine psoralea; through in-vitro cell experiment verification, the psoralen can activate NK-92 to secrete IFN-gamma, Granzyme B and Perforion, and activate surface protein NKG2D of NK-92; meanwhile, the psoralen also has the same effect on a cell group containing NK cells; through in-vivo experiment verification, the psoralen helps to improve the total amount of NK cells in the mouse spleen, inhibit tumor growth, and improve the expression amount of IFN-gamma, Granzyme B, Perforion, NKG2D, NKP46 and CD107a in a tumor infiltration environment. In summary, the small-molecule compound psoralen has good effect in activating NK cells.

The invention discloses health-preserving liqueur and a preparation process thereof. The health-preserving liqueur comprises the following raw materials: 0.2-1.8 parts of ginseng; 2.5 to 5.5 parts of fructus lycii; 2.5 to 5.5 parts of fructus rosae laevigatae; 0.2 to 1.8 parts of cortex cinnamomi; 0.5 to 3.5 parts of Chinese date; 2.5 to 5.5 parts of raspberry fruit; 0.5 to 3.5 parts of fructus psoraleae; 2.5 to 5.5 parts of herba cistanche; 0.5 to 3.5 parts of rhizoma polygonati; and 100-140 parts of a wine base. The health-preserving cordial has the beneficial effects that ginseng, medlar, cherokee rose fruit, cinnamon, Chinese date, raspberry, fructus psoraleae, cistanche and rhizoma polygonati are soaked in the wine base according to a set proportion to prepare the health-preserving cordial, under the combined action, the beneficial effects of supplementing each other can be achieved, and the health-preserving cordial can tonify qi, activate blood and relieve fatigue after being drunk, is suitable for preserving health, and has the effects of preserving health, promoting blood circulation and relieving fatigue. And the health-care wine can promote family harmony and is beneficial to the strong and healthy body of consumers.

The invention discloses a traditional Chinese medicine formula with a reproductive system radiation damage protection effect as well as a preparation method and application of the traditional Chinese medicine formula. The traditional Chinese medicine formula comprises the following components in parts by mass: 15-30 parts of Chinese yam, 6-15 parts of dogwood, 10-30 parts of astragalus membranaceus, 10-30 parts of prepared rehmannia root, 10-15 parts of spina date seed, 6-15 parts of fructus psoraleae, 5-15 parts of fructus lycii and 3-9 parts of rhodiola rosea. In the traditional Chinese medicine formula provided by the invention, all the components have a synergistic effect, so that the injury of ionizing radiation to a reproductive system can be effectively relieved, the pathological change of testis tissues is remarkably improved, sperm quality parameters are improved, the apoptosis process of testis cells is inhibited, the injury caused by oxidative stress is repaired, and the DNA injury degree is reduced; therefore, the technical defects of high toxicity, high cost, insufficient protective effect on the reproductive system and the like of the existing radiation protective agent are overcome.

The invention belongs to the technical field of essential oil, and particularly provides compound essential oil for coordinating intestines and stomach as well as a preparation method and application of the compound essential oil. The liquid compound essential oil comprises the following raw materials in parts by weight: 20-30 parts of black pepper essential oil, 20-25 parts of fructus psoraleae essential oil, 5-10 parts of clove essential oil, 10-15 parts of perilla essential oil, 10-15 parts of schisandra chinensis essential oil, 10-15 parts of fennel essential oil and 1-5 parts of sweet orange essential oil. According to the compound essential oil for coordinating intestines and stomach provided by the invention, medicinal and edible raw materials (which are originally used for coordinating intestines and stomach in a traditional Chinese medicine system) such as clove, purple perilla, black pepper, fructus psoraleae, fennel and the like are selected and compounded in an essential oil extract form, so that the limitation of single effect of single essential oil is broken through; the traditional'medicine pair 'and'prescription' thinking is converted into a compound system of modern aromatherapy, and the requirements of modern people on'nature, multiple effects and convenient conditioning 'are met.

The invention discloses a traditional Chinese medicine ointment for improving pancreas islet function and a preparation method and application thereof. The traditional Chinese medicine ointment is prepared from ginseng, astragalus membranaceus, radix ophiopogonis, salvia miltiorrhiza, corn stigma, radix polygonati officinalis, radices trichosanthis, dandelion root, Chinese yam, poria cocos, radix puerariae, purslane, potentilla discolor, cyclocarya paliurus, folium mori, liquorice, momordica grosvenori, radix rehmanniae recen, coptis chinensis, chrysanthemum, honeysuckle, buckwheat, rhizoma anemarrhenae, cinnamon, bitter gourd, gynostemma pentaphyllum, cortex lycii radicis, rhizoma phragmitis and the like according to a specific weight part ratio. The invention further provides a preparation method of the traditional Chinese medicine ointment. The preparation method comprises the steps of soaking in water, decocting and extracting, filtering and concentrating, ointment collecting and the like. The traditional Chinese medicine ointment can remarkably reduce fasting blood glucose and postprandial blood glucose of diabetic model mice and improve abnormal glucose tolerance, and has a protection effect on pancreas islet tissues. The traditional Chinese medicine ointment can be used for preparing health care products for assisting in reducing blood sugar or pharmaceutical compositions for preventing and assisting in treating type 2 diabetes mellitus, and has the advantages of reasonable formula, exact curative effect, stable preparation process and the like.

The invention relates to the technical field of preparation and application of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating Alzheimer's disease and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 3-9 parts of ginseng, 3-10 parts of morinda officinalis, 6-12 parts of dogwood, 3-10 parts of rhizoma acori graminei, 3-10 parts of polygala tenuifolia, 3-6 parts of rhodiola rosea, 3-6 parts of China rose, 2-3 parts of hypericum perforatum, 3-6 parts of saussurea involucrate, 9-15 parts of cortex lycii radicis, 3-12 parts of golden cypress and 1-5 parts of agilawood. The traditional Chinese medicine composition provided by the invention accords with the traditional Chinese medicine treatment concept of tonifying deficiency and filling marrow, inducing resuscitation and soothing nerves, dredging collaterals and eliminating evil, and tonifying spleen and assisting transportation, not only can relieve damage of neurons, but also can reverse alzheimer disease related disorder signal channels in neuronal cells, microglial cells and astrocytes.

The application belongs to the technical field of pharmaceutical technology analysis, and particularly relates to a method for establishing a fingerprint spectrum of a compound medicine. The method comprises preparation of a test sample solution, preparation of a control sample solution, and adoption of a specific gradient elution procedure. The method is simple, stable, reproducible, and highly precise, and can improve the quality control method of the compound medicine containing psoralea, walnut kernel, radix morindae officinalis, cistanche deserticola, eucommia ulmoides carbon, vinegar frankincense and vinegar myrrh, guarantee the reliable and stable quality of the compound medicine, and effectively control the quality of the compound medicine containing psoralea, walnut kernel, radix morindae officinalis, cistanche deserticola, eucommia ulmoides carbon, vinegar frankincense and vinegar myrrh, such as the quality of the modified Qingmo pill, so as to guarantee the stability, reliability and safety of the product.

The invention belongs to the technical field of health-care tea drinks, is homologous in medicine and food, and is prepared into agilawood tea pills with health-care functions by taking agilawood in a court secret prescription and various traditional Chinese medicinal materials as a formula and taking Chinese tea as a raw material in combination with a Chinese traditional pill preparation process. The tea pills have the health-care effects of enriching yin and nourishing kidney; according to the preparation method and the formula, the traditional Chinese medicine comprises various natural traditional Chinese medicinal materials such as freshwater sponge, lamp grass carbon, fructus cnidii, semen plantaginis, cistanche deserticola, semen cuscutae, malan flower, morinda officinalis, herba epimedii, piper cubeba, anise, fructus rosae laevigatae, fructus psoraleae, radix aucklandiae, fructus caryophylli, semen allii tuberosi, monkshood, polygala tenuifolia, rhizoma zingiberis, agilawood, rhizoma alismatis, semen juglandis, semen boitae, mantis egg-case, fructus lycii, pulp of dogwood fruit, poria cocos and radix rehmanniae preparata. The traditional Chinese medicine has the effects of nourishing yin and strengthening, warming and tonifying kidney qi, strengthening muscles and bones, coordinating intestines and stomach, improving dysmenorrhea, refreshing and restoring consciousness, and strengthening heart and lung.

The invention belongs to the technical field of traditional Chinese medicine preparations, and discloses a traditional Chinese medicine composition capable of regulating spleen and kidney to promote children to grow tall as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from rhizoma anemarrhenae, astragalus membranaceus, coptis chinensis, radix curcumae, liquorice, felwort, fructus alpiniae oxyphyllae, prepared rhizoma polygonati, acanthopanax, fructus psoraleae, semen cuscutae, glossy privet fruit, cistanche, prepared rhizoma cibotii, radix rehmanniae recen, prepared rehmannia root, agastache rugosus, schisandra chinensis, pericarpium citri reticulatae and poria cocos. The preparation method comprises the following steps: S1, preparing and pretreating raw materials: weighing the raw materials, cleaning, selecting and washing the raw materials, and then crushing the raw materials; s2, concentration and extraction: firstly decocting the pretreated raw materials, then separating, and finally concentrating to obtain the required traditional Chinese medicine composition. The traditional Chinese medicine composition can improve the problems of picky eating, anorexia, dyspepsia, sallow complexion, difficulty in falling asleep, night crying, dysphoria, irritability and the like, and can effectively promote children to grow tall.

The application provides a kind of assay method for screening specific liver injury components of Epimedium and Psoralea, comprising the steps of preparing mother liquor, preparing diluent, measuring after cell administration, animal experiment verification and metabolomics analysis.The application excavates the components of Epimedium and Psoralea medicinal materials, and finds that immune stress induced by TNF-alpha, immune promoting components in Epimedium and Psoralea and susceptible components of liver injury synergistically cause liver injury, which provides potential biological target for early warning, diagnosis and treatment of liver injury caused by compatibility of Epimedium and Psoralea, and ensures safe and reasonable use of clinical drugs.

The application relates to the technical field of bacteriostatic materials, and particularly discloses a kind of anti-penicillium film based on psoralea carbon quantum dots and a preparation method and application thereof.The anti-penicillium film comprises a biodegradable film-forming substrate and a photosensitizer, the photosensitizer comprises psoralea carbon quantum dots, the psoralea carbon quantum dots take psoralea as a carbon source, the particle size of the psoralea carbon quantum dots is 1-10 nm, and the anti-penicillium film is applied to fruit and vegetable preservation.The psoralea carbon quantum dots synthesized by taking traditional Chinese medicinal material psoralea as the only carbon source are used as the photosensitizer, and the anti-penicillium film prepared by the photosensitizer has the functions of active antibiosis and physical blocking, can efficiently generate a large number of active oxygen under blue light irradiation, can realize precise and physical killing of penicillium, effectively prolongs the shelf life of fruits and vegetables, and reduces postharvest loss of fruits and vegetables.

The invention provides a sugar-free decocted extract as well as a preparation method and application thereof, and belongs to the field of traditional Chinese medicine pharmacy. Radix asparagi, radix ophiopogonis, prepared rehmannia root, Chinese yam, radix achyranthis bidentatae, rehmannia root, folium cortex eucommiae, prepared polygonum multiflorum, poria cocos, ginseng, radix aucklandiae, semen boitae, schisandra chinensis, rhizoma cibotii, pepper, rhizoma alismatis, rhizoma acori graminei, polygala tenuifolia, semen cuscutae, fructus rosae laevigatae, fructus lycii, raspberry and cortex lycii radicis are decocted with water for three times; combining the decoction, and filtering; concentrating the filtrate, standing for 24 hours, taking supernate, concentrating to obtain clear paste, adding beta-cyclodextrin which is 5%-10% of the weight of the clear paste, and stirring the clear paste and the beta-cyclodextrin at 50-60 DEG C for 1-2 hours at the temperature of 50-60 DEG C; the weight of the xylitol is 2-3 times that of the clear paste, the weight of the sodium carboxymethyl cellulose is 1-3% that of the clear paste, the mixture is stirred at the temperature of 50-60 DEG C until the oral thick paste is uniform in texture, then the paste is collected at the temperature of 80 + / -5 DEG C, and the sugar-free decocted paste is obtained and is sweet in taste, free of other peculiar smells, uniform in state and free of layering and caking.

The application provides a traditional Chinese medicine composition for treating wind-heat syndrome in children and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating wind-heat syndrome in children comprises the following raw materials: mint, silkworm chrysalis, raw gypsum, anemarrhena, scutellaria, artemisia, figwort and psoralea. The traditional Chinese medicine composition can treat wind-heat syndrome in children, can significantly improve the clinical symptoms and signs of the children, and can improve the immunity of the children, and thus is high in effect and safety and worthy of clinical promotion and application.

A traditional Chinese medicine composition for treating myelosuppression during chemotherapy is prepared from the following traditional Chinese medicine materials in a weight ratio: 6-150 parts of raw astragalus, 2-50 parts of angelica, 2-50 parts of euphorbia humifusa, 2-50 parts of ligustrum lucidum, 2-50 parts of psoralea, and 2-30 parts of cuscuta. The traditional Chinese medicine composition can act on hematopoietic function through multiple components and multiple pathways, effectively improve myelosuppression caused by chemotherapy, and can be used to cooperate with chemotherapy, improve the completion rate of chemotherapy, and improve the quality of life during chemotherapy, with remarkable effects.

This invention discloses a traditional Chinese medicine composition that strengthens bones and relieves pain, repairs cartilage, improves osteoporosis, and calms the mind, belonging to the field of traditional Chinese medicine technology. This composition is derived from Guizhi Shaoyao Zhimu Decoction and Huanglian Ejiao Decoction, containing components such as cinnamon twig, white peony root, anemarrhena rhizome, prepared aconite root, coptis rhizome, scutellaria root, psoralea fruit, eucommia bark, and calcined oyster shell. It restores blood and qi supply to bones and joints by warming yang and dispelling cold, eliminating wind and dampness, and promoting blood circulation. Combined with tonifying the kidneys and strengthening bones, nourishing blood and softening tendons, it achieves cartilage repair, bone strengthening, and improvement of osteoporosis. It also clears heat and calms the mind, and can be used to treat bone pain, muscle and bone pain, cartilage wear, and osteoporosis caused by wind-cold-dampness obstruction, accompanied by symptoms such as irritability and insomnia. It has comprehensive therapeutic effects and high clinical application value.

The application discloses a traditional Chinese medicine composition for treating knee synovitis and a preparation method thereof, and particularly relates to the field of traditional Chinese medicines. The composition comprises a blood-activating and swelling-eliminating plaster and a qi-tonifying and swelling-eliminating soup. The blood-activating and swelling-eliminating plaster comprises angelica sinensis, ligusticum chuanxiong, red peony root, persicae semen, safflower, phellodendri cortex, raw olibanum, raw myrrh, dragon's blood, radix angelicae pubescentis, taraxacum, radix sanguisorbae, curcuma, raw rhubarb and mirabilite; and the qi-tonifying and swelling-eliminating soup comprises smilax glabra, atractylodes, coix seed, phellodendri cortex, radix cyathulae, motherwort, raw astragalus, alisma orientale, anemarrhena asphodeloides, psoralea, persicae semen, safflower and licorice. The research result of the blood-activating and swelling-eliminating plaster and the qi-tonifying and swelling-eliminating soup used in combination for treating knee synovitis has not only help to understand the action mechanism of the external treatment technology of traditional Chinese medicine, but also helps to develop a new treatment method with definite curative effect and no toxic side effect, and has remarkable social and economic benefits.

The invention discloses a method for detecting in-vivo substances after psoralea corylifolia administration, which is characterized in that 58 in-vivo substances of psoralea corylifolia can be simultaneously detected within 8 minutes by combining positive ion and negative ion scanning modes and combining reference substance quantification and virtual quantification by utilizing a liquid chromatography-mass spectrometry technology, and 11 groups of isomers can be simultaneously detected. Analysis of a mouse plasma sample shows that the method can resist matrix effect interference, and the quantitative lower limit of most compounds can reach 15.6 nM. The method provided by the invention is sensitive and reliable, and can powerfully support biological sample analysis after psoralea corylifolia administration.

The invention provides a Changchun and longevity oral liquid and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations. Asparagus cochinchinensis, radix ophiopogonis, prepared rehmannia root, Chinese yam, radix achyranthis bidentatae, rehmannia root, folium cortex eucommiae, radix polygoni multiflori preparata, poria cocos, ginseng, radix aucklandiae, semen boitae, schisandra chinensis, rhizoma cibotii, pepper, rhizoma alismatis, rhizoma acori graminei, polygala tenuifolia, semen cuscutae, fructus rosae laevigatae, fructus lycii, raspberry and cortex lycii radicis are soaked in water and then decocted; filtering to obtain filtrate; concentrating the filtrate under reduced pressure to obtain fragrant paste; adding xylitol, adding potassium sorbate at the same time, adding purified water, and stirring to completely dissolve the xylitol and the potassium sorbate; and cooling the prepared liquid medicine to room temperature, standing, finely filtering by adopting a precision filtering device, filling the finely filtered liquid medicine into an oral liquid bottle under an aseptic condition, and carrying out circulating steam sterilization, cooling, bottle wiping, labeling and packaging on the sealed oral liquid to obtain the Changchun and longevity oral liquid. The medicine can be taken once a bottle is opened, the dosage is accurate, carrying and taking are greatly facilitated, and medication compliance is improved.

The invention relates to the field of traditional Chinese pharmacology, and discloses an external ointment for traumatic injury, fracture and ostealgia and a preparation method thereof. The traditional Chinese medicine composition comprises the following components: herba lycopi, fructus aurantii, sappan wood, rhizoma atractylodis, rheum officinale, rhizoma atractylodis macrocephalae, frankincense, myrrh, rhizoma cyperi, peach kernels, pericarpium citri reticulatae viride, radix linderae, fructus psoraleae, radix paeoniae rubra, polygonum cuspidatum, rhizoma zingiberis, scutellaria baicalensis, safflower carthamus, lumbricus, eucommia ulmoides, radix achyranthis bidentatae, cinnamon, rhizoma sparganii, curcuma zedoary, asarum, cortex phellodendri, fossil fragments, rosa laevigata michx roots, radix curcumae, amber, native copper, pseudo-ginseng, resina draconis, cinnabar, catechu, red halloysite, chingma abutilon seeds, pollen typhae, clove, corydalis tuber and artemisia anomala. , stalactite, cuttlebone, saussurea involucrata and embelia laeta root. The traditional Chinese medicine composition has the effects of relieving swelling and pain, dispelling wind and eliminating dampness on rheumatism ostalgia, arthralgia and lumbocrural pain diseases such as tenosynovitis, frozen shoulder, knee osteoarthritis, cervical spondylosis, lumbar muscle degeneration, lumbar disc herniation and stiff neck; the effects of promoting blood circulation to remove blood stasis and relieving swelling and pain are also achieved on trauma such as traumatic injuries and fractures.

The invention relates to a traditional Chinese medicine composition for treating liver and kidney deficiency type leucoderma, the medicine composition is composed of active ingredients and medically acceptable auxiliary materials, and the active ingredients are prepared from the following raw material medicines in percentage by weight: 15-18% of glossy privet fruit, 15-18% of semen cuscutae, 10-12% of fructus psoraleae, 9-11% of nux prinsepiae, 12-15% of prepared rehmannia root, 9-11% of pseudo-ginseng, 12-15% of salvia miltiorrhiza and 9-11% of duckweed. The pharmaceutical composition disclosed by the invention has a remarkable effect of treating the liver and kidney deficiency type leucoderma.