73 results about "Fructus psoraleae extract" patented technology

The invention discloses a double-formula medicine used for treating insomnia, and a preparation method thereof. With existing insomnia-treating medicines, a simultaneous kidney invigorating, liver soothing and tranquilizing function can hardly be achieved. The medicine assists in solving the problem. With the medicine, various depressive insomnias can be treated with multiple targets, multiple links and multiple approaches. The double-formula medicine provided by the invention is composed by a formula A and a formula B. The formula A is composed of a Tiantai radix linderae extract, a corydalis tuber extract, panax notoginseng powder, a Chinese clematis root and rhizome extract, black common monkshood daughter root, an eucommia extract, and the like. The formula B is composed of a white mulberry root-bark extract, a psoralea corylifolia extract, a dipsacus asper extract, a silktree albizia bark extract, an oriental waterplantain tuber extract, an asiatic plantain seed extract, a Chinese arborvilae seed extract, a thinleaf milkwort root extract, a spine date seed extract, a common cnidium fruit extract, and the like. The invention also provides a preparation method of the double-formula medicine. With the method, various depressive insomnias can be treated with multiple targets, multiple links and multiple approaches. The medicine is advantaged in safe treatment, no toxic or side effect, fast effect, and thorough treatment.

The invention discloses a composition of malaytea scurfpea extract as well as the preparation method and use thereof. The composition contains a malaytea scurfpea extract, cyclodextrin and an optional excipient acceptable in the physiology. The extract of the invention has an excellent processing performance.

The invention relates to malaytea scurfpea extract, a medical composition containing the malaytea scurfpea extract, a preparation method for the medical composition and application of the medical composition. The malaytea scurfpea extract comprises 40 to 90 percent of malaytea scurfpea phenol and 2 to 10 percent of malaytea scurfpea flavonoid compositions, and does not comprise psoralen and isopsoralen. As proved by experiments, the malaytea scurfpea extract and the medical composition containing the malaytea scurfpea extract have stronger comprehensive function on estrogen beta receptors, and have better synergistic effect, so that the malaytea scurfpea extract and the medical composition containing the malaytea scurfpea extract are predicted to be used for treating climacteric syndrome, breast carcinoma and / or cardiovascular and cerebrovascular diseases.

Disclosed herein are an anti-obesity agent from natural products based on angiogenesis inhibitory actions, and an angiogenesis inhibitor or a composition for inhibiting obesity, containing at least one selected from the group consisting of Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract. Because the Psoraleae Semen extract, Siegesbeckiae Herba extract, and Corni Fructus extract of the present invention exhibit angiogenesis inhibitory effects and obesity inhibitory effects, they may be usefully used as an agent for prevention and treatment of angiogenesis-related diseases or obesity.

The invention belongs to the field of traditional Chinese medicines, relates to a pharmaceutical composition for adjusting estrogen level as well as a preparation method and application thereof, and in particular relates to a method for preparing the pharmaceutical composition. The method comprises the steps of preparing a fructus psoraleae extract and preparing a eucommia ulmoides extract, a radix salviae miltiorrhizae extract and a rhizoma anemarrhenae extract. The invention also relates to the pharmaceutical composition prepared by the method. The pharmaceutical composition comprising the fructus psoraleae extract, the eucommia ulmoides extract, the radix salviae miltiorrhizae extract and the rhizoma anemarrhenae extract is basically free of toxicity for liver, and can effectively prevent and treat diseases related to the imbalance of in-vivo estrogen level or reduce the symptom.

The invention relates to the field of medicines and health care food, and particularly relates to a formula composition and a medicinal preparation with effects of increasing bone density and treating bone joint pain, a preparation method of the medicinal preparation and an application of the formula composition. The formula composition comprises N-sulfo-glucosamine potassium salt, calcium carbonate, collagen, fructus psoraleae extractive, and casein phosphopeptides. The formula composition can be prepared into various dosage forms to be used as medicines or health care food. The formula composition and the medicinal preparation thereof can effectively increase bone cell proliferation and the bone density, prevent various kinds of discomfort caused by bone loss and relieve bone joint pain, and have no toxic or side effects.

The invention belongs to the field of traditional Chinese medicine preparations, and relates to a processing method of fructus psoraleae medicinal materials. The method particularly comprises the steps that fructus psoraleae medicinal materials are extracted through water, a water extract solution is discarded, dregs of a decoction are collected, and fructus psoraleae extract which can be used as medicine is obtained. In addition, the invention further relates to the fructus psoraleae extract prepared through the processing method and a pharmaceutical composition containing the fructus psoraleae extract. By means of the processing method, most of water-soluble components such as psoralenoside and isopsoralenoside are removed, and hepatotoxicity damage of the fructus psoraleae extract is effectively reduced.

The invention discloses a lotus leaf-based preparation for treating phlegm and blood stasis simultaneously. The pharmaceutical composition is prepared from the following traditional Chinese medicine extracts in parts by weight: 40-80 parts of lotus leaf extract, 10-20 parts of salvia miltiorrhiza extract, 30-60 parts of hawthorn extract, 10-20 parts of malaytea scurfpea fruit extract or salt scurfpea fruit extract, and 1-3 parts of senna extract. The invention further discloses application of the lotus leaf-based preparation in the preparation of medicines for treating phlegm turbidity and blood stasis simultaneously. The lotus leaf-based preparation disclosed by the invention has the activity in lowering blood lipid levels, and can be used for treating phlegm and blood stasis simultaneously and lowering the blood lipid levels.

The invention discloses compound skin cream for treating leucoderma and a preparation method thereof, and belongs to the technical field of external-use traditional Chinese medicine. The cream is prepared through the method comprising the steps that 1, fructus psoraleae extract and radix angelicae dahuricae extract are prepared; 2, oil-phase raw materials are prepared; 3, water-phase raw materials are prepared; 4, the oil-phase raw materials and the water-phase raw materials are heated, stirred and then emulsified; 5, the temperature a main pot is reduced to 62 DEG C, the fructus psoraleae extract and the radix angelicae dahuricae extract which are prepared in the step 1 are added for emulsification, and high-pressure homogenizinng is carried out for several circles; 6, after cooling, garland flower essence is added, discharging is carried out when the temperature is reduced to 37 DEG C, and the cream is obtained. The compound skin cream and the preparation method thereof have the advantages that the compound skin cream is directly applied to an affected part, and the pain of a patient during treatment is relieved; the fructus psoraleae extract and the radix angelicae dahuricae extract with the effects of stimulating and activating the activity of tyrosinase, stimulating melanocytes and enhancing the melanin synthesizing capacity are adopted, and therefore the compound preparation has a good treatment effect.

The invention relates to a mixed preparation, in particular to a mixed preparation for preventing and controlling plant diseases and insect pests, and application thereof. A mixture is mixed by a component A and a component B at the mass ratio of 99:1 to 1:99, wherein the component A is fructus psoraleae extractive, and the component B is each class of pesticide effective ingredients and each class of pesticide effective ingredients is one or more of agricultural antibiotic, amide compound, triazole compound, methoxyl acrylate compound, amino acid derivative compound, sulfamide compound, diarylketone compound, oxime ether compound, isoxazoline compound, benzimidazole compound, organic chloride compound, phenylpyrrole compound, imidazole compound, isoprothiolane, Fernasan, mancozeb, hymexazol, cnidium lactone, amino-oligosaccharin, chitin and mushroom proteoglycan. When the mixture disclosed by the invention is adopted, the prevention and controlling effect can be enhanced; the mixturecan also be used for treating various diseases simultaneously happening in a crop growing period in one-time medicine utilization; multiple repeated field operations can be finished in one time; laborforce is saved; cost is lowered.

The invention discloses a medicament for killing sperms in vitro, which comprises the raw materials in percentage by weight: 3-7mg of platycodin D, 3-5mg of divaricate saposhnikovia extract, 3-5mg of cassia twig extract, 1-3mg of malaytea scurfpea extract and 130-170ml of 0.9 percent physiological saline. The platycodin D, the divaricate saposhnikovia extract, the cassia twig extract, and the malaytea scurfpea extract are added into a vessel for uniformly mixing and then 130-170ml of 0.9 percent physiological saline is added into the vessel for uniformly shaking to obtain the medicament. The medicament is prepared from pure traditional Chinese medicine, can rapidly achieve the aim of killing the sperms in vitro and has better antimicrobial effect and sterilizing effect. The medicament can be prepared into emulsion, suppository and other forms for external contraception of vagina, or can be prepared into sustained-release capsules which are placed in an intrauterine device and are carried to enter a human body, so that the contraception effect of the intrauterine device can be enhanced and no toxic and side effect are generated.

The invention relates to a Chinese medicinal composition for treating osteoporosis, wherein the active constituent is the significant portion of total-coumarines of fructus psoraleae extracted from traditional Chinese medicament of psoralea fruit. The invention also provides the process for preparing the medicinal composition and related dose forms.

The invention relates to the technical field of traditional Chinese medicine extraction and purification, in particular to a purification method of the effective components in psoralea, i.e. psoralen and isopsoralen. The method firstly uses low-concentration ethanol for eluting impurities after the psoralea extract is absorbed by macroporous absorptive resin, later uses high-concentration ethanol for elution, and then collects high-concentration ethanol eluate, recycles ethanol, dries the residue in vacuum and implementing grinding, and finally obtains the psoralen and isopsoralen rich sediments. By using the purification method of the invention, the total purity of the obtained psoralen and isopsoralen reaches more than 50 percent; and the purification method is applicable to the industrial mass production.

The invention discloses bone-invigorating sheep soup special for astronauts and a preparation method of the bone-invigorating sheep soup. The bone-invigorating sheep soup is prepared from the following raw materials in percentage by mass: 5%-10% of auricularia auricula polysaccharide, 15%-30% of lycium barbarum polysaccharide, 5%-10% of a herba epimedii extract, 10%-15% of a radix morindae officinalis extract, 10%-15% of a fructus psoraleae extract, 2%-5% of a sharpleaf galangal fruit extract, 2%-5% of a fructus ligustri lucidi extract, 2%-5% of a herba ecliptae extract, 5%-10% of a radix dipsaci extract, 10%-15% of a cortex eucommiae extract and 2%-5% of a semen cuscutae extract. The pharmaceutical extracts are combined to have the efficacies of nourishing the liver, kidneys and stomach, tonifying the spleen, strengthening muscles and bones and protecting the bones of the astronauts to a certain extent during a flight mission, and the adverse effects caused by body bone loss induced by a space environment to the astronauts are reduced.

The invention relates to a health food composition for increasing the bone mineral density, and a preparation method thereof. The health food composition includes, by weight, 25-50 parts of Malaytea Scurfpea Fruit extract, 25-50 parts of Radix Puerariae extract, 20-40 parts of panax notoginseng total saponins, 100-130 parts of D-glucosamine hydrochloride, 120-150 parts of calcium carbonate and 80-120 parts of hydrolyzed collagen. The preparation method comprises the following steps: respectively extracting Malaytea Scurfpea Fruit and Radix Puerariae with different concentrations of ethanol, respectively mixing the Malaytea Scurfpea Fruit extract, the Radix Puerariae extract, panax notoginseng total saponins, D-glucosamine hydrochloride, calcium carbonate and hydrolyzed collagen with a proper amount of other added clinically acceptable auxiliary materials, and processing through a routine technology to prepare a hard capsule, a tablet, a granule, a pulvis, a bagged tea, a soft capsule and other oral solid preparations. The health food composition has a bone mineral density increasing function, is safe, has no toxic or side effects, can be taken for a long term, and can be used in prevention and auxiliary treatment of osteoporosis.

The invention discloses special edible bone strengthening gelatin for astronauts and a preparation method thereof. The special edible bone strengthening gelatin is prepared from 5-10wt% of Radix Morindae Officinalis extract, 5-10wt% of Rhizoma Drynariae extract, 5-10wt% of Herba Epimedii, 5-10wt% of Radix Rehmanniae Preparata extract, 10-15wt% of Fructus Psoraleae extract, 2-5wt% of Cortex Eucommiae extract, 2-5wt% of Radix Achyranthis Bidentatae extract, 2-5wt% of Radix Astragali extract, 2-5wt% of Radix Polygoni Multiflori extract, 2-5wt% of Radix Puerariae extract, 1-5wt% of Radix Salviae Miltiorrhizae extract and 15-30wt% of pine polyphenol nanoparticles. The problem of bone loss of the astronauts in a space flight process is solved while the defect of high toxicity or severe side effects of existing protective agents is overcome. By extraction of various active polyphenol components with protective effects on weightlessness bone loss from natural plants, the special edible bone strengthening gelatin has advantages of scientific and reasonable ratio, low cost, convenience in administration and high safety.

The invention discloses gynostemma pentaphylla shampoo, which comprises the following components in parts by weight: 6 parts of octadecanol, 3 parts of wool grease, 8 parts of fructus psoraleae extractive, 5 parts of gynostemma pentaphylla extractive, 4 parts of hydrolyzed collagen, 0.01 part of preservative, 0.01 part of essence, 0.02 part of pigment and 18 parts of purified water. The shampoo is prepared by the following steps: heating octadecanol and the wool grease to 75 DEG C; heating the fructus psoraleae extractive, gynostemma pentaphylla extractive, the hydrolyzed collagen and the purified water to 75 DEG C; and mixing the two groups of mixtures, adding the preservative, the essence and the pigment after the temperature is cooled to 45 DEG C, and evenly stirring. The gynostemma pentaphylla shampoo has a hair-growing and calvities-preventing function and an antibacterial action, and can prevent folliculitis as well as relieve itching and remove dandruffs.

The invention discloses an anti-hair loss Chinese herbal medicine compound with antagonism androgen receptor expression, belonging to pharmaceutical compositions. The anti-hair loss Chinese herbal medicine compound contains an astragalus extract, a dodder extract, a scutellaria baicalensis extract, a pueraria extract, a rhizoma chuanxiong extract, a malaytea scurfpea fruit extract, a rhizoma coptidis extract and a shrubby sophora extract, wherein the weight percentage of each Chinese herbal medicine extract accounting for the total weight of the anti-hair loss Chinese herbal medicine compound is 0.1%-99%. The anti-hair loss Chinese herbal medicine compound with antagonism androgen receptor expression disclosed by the invention is used for treating seborrheic alopecia caused by male androgen source character.

The invention belongs to the technical field of a fertilizer, and particularly discloses a specific fluid fertilizer for improving wheat anti-freezing ability; the specific fluid fertilizer is prepared from, copper acetate, citric acid manganese chelate, potassium sorbate, ethyl maltol, L-glutamic acid, nutrition juice, fructus psoraleae extractive, and hypericum japonicum extractive. The specific fluid fertilizer can effectively promote synthesis of multiple cold-resisting and freeze-resisting new proteins, and change the metabolism way of a wheat plant, thus the wheat can enter cold-resisting and freeze-resisting acclimation; the new compounded proteins are grouped to a cell membrane or attached to the surface of the cell membrane, and have effects of protecting and stabilizing the cell membrane; the new compounded proteins are distributed in the vacuole and cell gap to prevent freezing, thus the cell sap is in an over-cooling state under the low temperature, thereby preventing freezing damages and improving freeze resistance of the wheat plant; the fertilizer can effectively balance the nutrition structure of the inner part of the wheat plant, promote the growth of roots and stems, effectively reduce lodging rate, increase the wheat maturing rate and improve wheat maturing quality.

The invention provides applications of a human carboxylesterase inhibitor using an extract product or monomer components of Psoralea corylifolia, and the applications belong to the field of medicine technology. The human carboxylesterase inhibitor using the extract product or monomer components of Psoralea corylifolia is used for alleviating delayed-onset diarrhea caused by a plurality of clinic chemotherapeutics or improving bioavailability of ester medicaments and prolonging metabolic half-life of the medicaments. The extract product of Psoralea corylifolia is a 25%-95% ethanol extract; main monomer chemical components of the extract product of Psoralea corylifolia comprise: neobavaisoflavone, corylifolinin, corylifolin A, bavachinin A, bakuchiol, bavachin or isobavachin. In vitro activity determination shows the IC50 value of the extract product of Psoralea corylifolia or monomer components for inhibiting carboxyle sterase is 0.8-6.4 micromole, the safety of the compounds is good, which prompts the fact that the compounds have good application prospects.

The invention discloses chocolate with the effect of improving immunity. The chocolate is characterized by being added with tea polyphenol accounting for 0.01%-1% of the total weight of the chocolate, aloe extract accounting for 0.01%-1% of the total weight of the chocolate, salidroside accounting for 0.01%-1% of the total weight of the chocolate, biological active peptides accounting for 0.01%-1% of the total weight of the chocolate, active calcium accounting for 0.01%-1% of the total weight of the chocolate, radix acanthopanacis semticosi extract accounting for 0.01%-1% of the total weight of the chocolate, fructus psoraleae extract accounting for 0.01%-1% of the total weight of the chocolate, coix seed extract accounting for 0.01%-1% of the total weight of the chocolate, orange peel extract accounting for 0.01%-1% of the total weight of the chocolate, tuber fleeceflower stem extract accounting for 0.01%-1% of the total weight of the chocolate, wild rice shoot extract accounting for 0.01%-1% of the total weight of the chocolate, cornua cervi pantotrichum extract accounting for 0.01%-1% of the total weight of the chocolate, cod liver oil accounting for 0.01%-1% of the total weight of the chocolate, flos chrysanthemi extract accounting for 0.01%-1% of the total weight of the chocolate, propolis accounting for 0.01%-1% of the total weight of the chocolate, pteridium aquilinum extract accounting for 0.01%-1% of the total weight of the chocolate, common yam rhizome extract accounting for 0.01%-1% of the total weight of the chocolate, zinc-enriched yeast accounting for 0.01%-1% of the total weight of the chocolate and okra extract accounting for 0.01%-1% of the total weight of the chocolate. According to the chocolate, the durability of functional active factors is achieved while easy chewing is achieved, and the nutritional healthcare effects of refreshing people, resisting fatigue, improving the organism immunity and the like are achieved; meanwhile, an original gum base is not destroyed, and the production cost is reduced.

The invention belongs to the field of health foods, and discloses fishbone collagen peptide calcium noodles and a preparation method thereof. The noodles are prepared from, by weight, 70-80 parts of flour, 10-20 parts of millet flour, 5-10 parts of skim milk powder, 5-10 parts of peanut powder, 0.5-1 part of fructus psoraleae extracts, 0.5-1 part of osteopractic total flavone, 0.1-0.5 part of fishbone collagen peptide calcium chelate, 0.5-1 part of icariin, 0.001-0.005 part of vitamin D and 1-2 parts of table salt. The fishbone collagen peptide calcium noodles prepared by using the method canimprove the bone mineral density of a patient suffering from osteoporosis, and effectively slow the osteoporosis process; moreover, an OPG / RANK / RANKL cell factor system can be regulated through the mediated ROS level so as to inhibit the development of the osteoporosis, and the aim of reducing the occurrence of the osteoporosis is achieved. Therefore, the fishbone collagen peptide calcium noodlesprepared by using the method have the effect of preventing and treating the osteoporosis.

The invention provides a psoralea corylifolial total glycoside extract which mainly contains 40 to 50 percent of psoralea corylifolial glycoside as well as 40 to 50 percent of isopsoralen glycoside. The psoralea corylifolial total glycoside extract and dressing or excipient allowed in pharmaceutics are prepared into any preparation formulation disclosed in pharmaceutics and can also be matched with other medicines or components to be prepared into a preparation together for use. Proved by pharmacological test, the psoralea corylifolial total glycoside and the psoralea corylifolial glycoside and the isopsoralen glycoside contained thereof can all resist the reduction of leucocyte caused by cyclophosphamide and have remarkable immunologic enhancement, and can be applied to the preparation of the medicines for increasing leucocyte.

The invention provides a preparation method and an application of a non-decocted fructus psoraleae preparation and belongs to the technical field of traditional Chinese medicine preparation. The preparation method of the non-decocted fructus psoraleae preparation comprises steps as follows: primary extraction of effective ingredients is performed in a mode of combination of water immersion and ultrasonic extraction, secondary extraction is performed through ethanol extraction, and the non-decocted fructus psoraleae preparation is obtained through concentration, drying and superfine grinding finally. The preparation can be used for preparing a compound preparation containing fructus psoraleae or fructus psoraleae extracts. Therefore, the problem that the utilization rate of raw materials is low, the effective ingredients are severely damaged and the extraction efficiency is not high when a conventional single method is adopted for extraction are solved, the whole technological process is simple to control, synergistic interaction of the steps is realized, accordingly, the active ingredients of the fructus psoraleae are effectively protected, and the availability of a finished product is improved better.

The present invention relates to Psoralca corylifolia and new application of its fat-soluble portion in medicine. They have obvious action for resisting helicobacter pylori (Hp), and can be used for curing the diseases of gastritis and peptide gastric ulcer, etc. resulted from helicobacter pylori infection, in particular, they are good therapeutic effect for curing active gastritis, gastric erosion, gastric ulcer and duodenal ulcer, and have the action for curing and preventing the diseases of gastric lymph tissue (MALT) lymphoma and early gastric cancer, moderate intestinal glands metaplasia or atypical hyperplasia.

The invention relates to a fructus psoraleae extract. The fructus psoraleae extract does not contain psoralen and isopsoralen, meanwhile the weight content of the psoralen is above 80%, and the yield of the extract is above 10%. The extract can remarkably increase the bone mineral density of a patient suffering from osteoporosis and promote the effects of normal skeletal development and calcification.

The invention belongs to the field of nutrition and health care and relates to a composition with the function of relieving joint inflammation pain. The composition is prepared from dimethyl sulfone, hyaluronic acid, collagen, vitamin K, drynaria rhizome extracts, epimedium extracts, malaytea scurfpea fruit extracts, radix notoginseng extracts and eucommia bark extracts. The composition is used for joint inflammation, the kidney yang tonifying, muscle and bone strengthening and blood stasis and pain removing theory in traditional Chinese medicine is adopted and combined with the element supplementing and inflammation eliminating functions in modern nutriology, and the pain symptom of patients suffering from arthritis can be effectively relieved. Besides, the composition can be prepared into capsules in a perfusion mode and pressed into tablets and can be conveniently taken by patients.