Traditional Chinese medicine composition for treating hyperlipidemia and preparation method thereof
A technology of hyperlipidemia and composition, applied in the field of traditional Chinese medicine, can solve the problems of low content of active ingredients, incomplete absorption, inconvenient carrying, etc.
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Embodiment 1
[0086] 1. (1) Add 4 times of 60% ethanol to the crushed lotus leaf, adjust the pH to 12.0, reflux and extract twice at 75°C for 2 hours each time, and collect the extract for later use;
[0087] (2) Add 4 times of 85% ethanol to the residue of the lotus leaf medicinal material obtained in (1), adjust the pH to 3.0, reflux and extract at 75°C for 3 times, each time for 2 hours, and collect the extract for later use;
[0088](3) Centrifuge and filter the supernatant of the extract in (1), and reclaim ethanol by distillation under reduced pressure, adjust the pH to 7.0, then centrifuge and filter, take the supernatant and prepare a 3mg / mL solution, pump Into the AB-8 macroporous resin column for adsorption, the loading volume is 4BV, after gradient elution with pure water, 20% ethanol 2BV each, and elution with 70% ethanol, the eluate is collected, and the ethanol is recovered under reduced pressure. Evaporate and concentrate at a temperature of 0.06MPa-0.09MPa and 65°C-85°C to o...
Embodiment 2
[0097] 320g of lotus leaf extract, 160g of salvia miltiorrhiza extract, 240g of hawthorn extract, 160g of salt psoralen extract and 4g of senna leaf extract prepared in the 1-5 steps of embodiment 1 are mixed, add sugar powder, starch, Low-substituted hydroxypropyl cellulose and other auxiliary materials are used in appropriate amounts to prepare 1000 g of granules.
Embodiment 3
[0099] Mix 160g of lotus leaf extract, 20g of salvia miltiorrhiza extract, 120g of hawthorn extract, 20g of salt psoralen extract, and 6g of senna leaf extract prepared in steps 1-5 of Example 1, add starch, low-substituted hydroxyl Appropriate amount of auxiliary materials such as propyl cellulose, made into granules, and packed into 1000 capsules.
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