40 results about "Crataegus monogyna" patented technology

The invention discloses a method for assisting hawthorn breeding based on phenotypic omics, and relates to the technical field of phenotypic omics assisted hawthorn breeding. Comprising the following steps: S1, acquiring phenotypic data of normally growing hawthorns by using a high-throughput imaging system and a phenotypic analysis system, and detecting and analyzing various characters of the hawthorns; s2, establishing a hawthorn multi-dimensional phenotypic group database, and obtaining hawthorn breeding key character quantitative indexes; s3, constructing a phenotype-genotype correlation model according to the obtained hawthorn breeding key character quantitative indexes, and mining new functional genes to realize early prediction of breeding; and S4, creating a phenotype exponential weighting algorithm for parent matching. The method for assisting hawthorn breeding based on phenotypic omics is established, the problems of long hawthorn breeding period and high cost are solved, and the hawthorn breeding efficiency is effectively improved.

The invention discloses a composition for improving adverse effects of chemotherapy as well as a preparation method, application and a product of the composition, and particularly relates to the technical field of medicines. The composition comprises the following raw materials: tortoise, soft-shelled turtle, antler, sea cucumber, fructus amomi, pericarpium citri reticulatae and hawthorn. Alkaline protease and flavourzyme are adopted for enzymolysis, and the obtained composition can remarkably reduce the tumor volume of tumor-bearing animals, increase the bone marrow DNA content of chemotherapy animals and remarkably increase the number of white blood cells and the number of red blood cells in peripheral blood of the chemotherapy animals. The composition disclosed by the invention is used for preparing related products for improving the adverse effects of chemotherapy, and the prepared products are easy to absorb and have a remarkable improvement effect on the adverse effects of chemotherapy.

The invention discloses a fertilizer for promoting and improving the immunity of plants and a preparation method, and relates to the field of fertilizers. The preparation method comprises the following steps: mixing, smashing and grinding earthworms, eucalyptus leaves, wheat leaves and hawthorn leaves, putting into an ethanol solution, oscillating for 20-24 hours in a shaking table, and centrifugally filtering to obtain an active extracting solution; adding a sodium alginate solution into the suspended bacteria solution and the active extracting solution, and slowly adding carboxymethyl chitosan and a calcium chloride solution; and preparing. According to the invention, the plant growth-promoting rhizobacteria are fixed in the composite hydrogel, and the composite hydrogel can promote colonization of strains at plant root tips and lateral roots so as to regulate deposition of endothelial cell suberite, optimize mineral nutrition balance and abiotic stress response of plants and improve accumulation of auxin at the root tips; meanwhile, an active extracting solution is added into the composite hydrogel, immune response can be activated, and the metabolic activity and antioxidant activity of plants are greatly improved in combination with extracts of other substances.

The invention relates to the technical field of microbial fermentation engineering, and particularly discloses natto red yeast rice herb bean flour and a preparation method thereof. The preparation method comprises the following steps: respectively activating specifically preserved bacillus natto and monascus to obtain secondary seed solutions; inoculating the two seed solutions into a solid-state fermentation culture medium for co-fermentation; and inactivating, drying and crushing the fermentation product to obtain a finished product. The solid-state fermentation culture medium is prepared by compounding a bean matrix (soybeans, black beans or chickpeas) and herb tea components (roses, lotus leaves, chrysanthemums, mulberry leaves, haws, cassia seeds and the like). Through the synergistic effect of the bacillus natto and the monascus, nattokinase and monacolin K are efficiently enriched in a single fermentation system at the same time, conversion of soy isoflavone to a high-bioavailability aglycone type is remarkably promoted, and the obtained product has multiple health-care functions of thrombolysis, lipid reduction, efficient absorption and the like.

The invention discloses a hawthorn disease identification method based on a deep convolutional neural network and a disease image, and is applied to the technical field of hawthorn disease prevention and control. Comprising the following steps: collecting hawthorn disease image data as a training sample, distinguishing healthy plants and disease plants in a manual labeling manner, and refining to disease categories and disease degrees; carrying out data cleaning, data enhancement, data set expansion and normalization processing, constructing and training a deep convolutional neural network model for disease identification, and testing the detection performance by adopting a multi-dimensional evaluation index; and acquiring an image of a to-be-detected hawthorn plant, and inputting the image into the hawthorn disease identification model for real-time identification. According to the method, the pre-trained deep convolutional neural model is combined with the multi-scale data enhancement strategy and the adaptive transfer learning technology, the hawthorn disease intelligent identification system for the complex plant image scene is constructed, high-precision identification and automatic efficient detection of multiple diseases of hawthorns can be realized, and the real-time monitoring requirement of an orchard is met.

The invention discloses a culture optimization method of brevibacillus laterosporus and application of brevibacillus laterosporus in inhibiting pathogenic bacteria of hawthorn, an LB liquid culture medium is adopted in the culture process, and the culture medium comprises the following components: 10 g / L peptone, 15 g / L sucrose and 10 g / L yeast powder; the initial pH of fermentation is 7-8, the culture temperature is 30-35 DEG C, the rotating speed is 180-200rpm, the culture time is 24-36 hours, and the inoculum size of the brevibacillus laterosporus CB-528 bacterial liquid is 3-5vol%, and finally obtaining the fermented bacterial liquid through fermentation. The zymophyte liquid prepared on the basis of the method can be used for preparing biopesticides for preventing and treating Chinese yam diseases. The fermentation process disclosed by the invention is simple to control, easy to operate and obvious in effect, and the thallus yield and the spore rate can be greatly improved under the fermentation process. The fermentation culture solution disclosed by the invention has the characteristics of high activity, high viable organism content and high spore rate, and can prolong the preservation time of a subsequent preparation and improve the drug effect stability of the preparation.

The invention discloses a method for simultaneously purifying triterpenoids, hawthorn flavonoids and hawthorn polysaccharides from hawthorn, which comprises the following steps: crushing a hawthorn medicinal material, extracting, performing macroporous resin graded adsorption, performing gradient elution, performing membrane separation and the like to respectively obtain hawthorn extracts rich in triterpenoids, hawthorn flavonoids and hawthorn polysaccharides. According to the method, hawthorn is used as a raw material, the extraction, separation and purification method is simple, the used solvent is green, pollution-free and low in cost, hawthorn extracts rich in triterpenoids, hawthorn flavonoids and hawthorn polysaccharides are respectively obtained through macroporous resin graded adsorption, gradient elution, membrane separation and other methods, the effects of squeezing to be dry, taking all hawthorn flavonoids and comprehensively utilizing hawthorn flavonoids are achieved, the utilization rate is high, and the method is suitable for industrial production. The utilization value of hawthorn is improved, and the application prospect is wide.

The invention discloses a formula and a preparation method of a stomach-invigorating parasite-expelling tablet for livestock. The parasite expelling tablet is formed by compounding and tabletting parasite expelling core enteric particles A and stomach invigorating and relieving quick-release particles B. The particles A contain praziquantel and levamisole or salts thereof, and are coated with enteric materials, so that the parasite expelling activity is limited in gastric segment release and is quickly released in intestinal segment; the particles B contain a cortex meliae extract, a fructus quisqualis extract, pericarpium citri reticulatae, fried malt and fructus crataegi, are compounded with mucous membrane protection or adsorption stimulation components such as sodium alginate / pectin / montmorillonite and the like, and are subjected to post-treatment adsorption through essence, so that the taste covering stability is improved. The preparation method comprises the following steps: plant extraction, wet granulation in two ways, enteric coating of particles A, essence post-treatment of particles B, and compounding, lubricating and tabletting. According to the scheme, the insect expelling effect is guaranteed, gastrointestinal stimulation is reduced, the voluntary ingestion rate and administration compliance are improved, and the composition is suitable for dogs, cats and livestock to expel insects by oral administration.

The invention discloses an extraction method of hawthorn exosomes and application of the hawthorn exosomes in treatment of DSS-induced colitis, and belongs to the technical field of plant exosomes. The extraction method comprises the steps of raw material treatment, differential centrifugation, membrane filtration, ultracentrifugation enrichment, density gradient purification and desugaring refining, and the high-purity crataegus pinnatifida exosome with the capsule-shaped structure can be obtained. The hawthorn exosome intervenes DSS-induced colitis through preventive intragastric administration (25-50 mg / kg / d), the disease activity index (DAI) can be reduced to 2 or below, the expression quantity of colon tissue TNF-alpha is recovered to the normal level, the IL-1beta inhibition effect is superior to that of a hawthorn extract, and the curative effect is remarkably superior to that of plant exosomes such as rhizoma curcumae longae, tea leaves and black tea. The process is standardized, the curative effect is definite, and a new scheme is provided for colitis treatment.

This invention discloses a composition and its preparation method for treating human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN), belonging to the field of traditional Chinese medicine technology. The formula consists of 6-15 parts of American cockroach, 5-11 parts of hawthorn, 5-11 parts of chicory, 3-9 parts of *Scutellaria baicalensis*, 8-20 parts of *Sophora flavescens*, and 6-15 parts of *Cnidium monnieri*, and also contains 0.01-1 parts by weight of toad venom. The dosage form is one or more of the following: external gel, rinse, foam, suppository, and film preparation. It has high safety and is suitable for HPV infection and CIN changes, solving the problem of poor efficacy in existing treatments.

The invention belongs to the technical field of biological medicines, and particularly discloses a cardiomyopeptide freeze-dried composition as well as a preparation method and application thereof. The cardiomyopeptide freeze-dried composition comprises the following components in parts by mass: 12-15 parts of cardiomyopeptide, 8-11 parts of radix ophiopogonis, 6-8 parts of schisandra chinensis, 3-5 parts of hawthorn, 1-2 parts of spirulina powder and 1-2 parts of blueberry powder. The invention discloses a cardiomyopeptide freeze-dried composition and a preparation method and application thereof. The cardiomyopeptide freeze-dried composition is high in activity and good in stability, can relieve myocardial damage and can be applied to preparation of drugs for nourishing myocardium and protecting blood vessels.

The application provides a blood-activating and stasis-removing medicinal composition containing fermented douchi and a preparation method thereof, belongs to the technical field of biological medicine, and the medicinal composition comprises fermented douchi, drynaria extract, extract of pereskia aculeata, tanshinone II A, notoginsenoside R1, ligustrazine, rhodioside, total flavones of hawthorn leaves and total flavones of mulberry leaves. The fermented douchi is prepared from soybeans and black beans through fermentation by bacillus subtilis and bacillus coagulans. The drynaria extract is prepared from drynaria powder through common enzymolysis by cellulase, chitinase and beta-glucanase, extraction by a two-phase solvent, and purification by a dextran gel column. The extract of pereskia aculeata is prepared from pereskia aculeata powder through common enzymolysis by pectinase, cellulase and xylanase, common enzymolysis by bromelain and subtilisin, and purification by a macroporous adsorption resin column. The medicinal components are prepared in a specific proportion to relieve blood stasis from two dimensions of "improving blood flow dynamics + preventing thrombus formation".

The present application provides a kind of shrimp breeding phagostimulant and its preparation method.The phagostimulant comprises the following components by weight: 10-30 parts of schisandra chinensis, 150-200 parts of hawthorn powder microcapsule, 1-10 parts of baking soda, and 0.1-1 part of phagostimulant aid.The phagostimulant prepared by the present application, when applied to the growth test of grass shrimp with feed, can increase the yield per mu of grass shrimp by 127.6%-159.2%, and the growth rate, feeding rate and survival rate are all significantly better than conventional aquaculture, and no stress, disease and water ecological imbalance of shrimp body are caused during the aquaculture process, which meets the non-polluting fishery drug standard, and the effect is stable and reliable when used in different aquaculture areas, with strong adaptability.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating atherosclerosis and a preparation method thereof. The traditional Chinese medicine composition for treating atherosclerosis is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix astragali seu hedysari, 7 to 10 parts of radix notoginseng, 10 to 20 parts of poria cocos, 5 to 15 parts of lotus leaves, 10 to 15 parts of raw fructus crataegi, 10 to 20 parts of radix salviae miltiorrhizae, 10 to 15 parts of radix angelicae sinensis and 2 to 10 parts of ramulus cinnamomi. The traditional Chinese medicine composition can intervene in the atherosclerosis process through multiple ways of adjusting the blood fat level, improving aorta pathological injury, inhibiting inflammatory response, increasing intestinal flora diversity and the like, and the comprehensive treatment effect of the traditional Chinese medicine composition is equivalent to that of clinical conventional medicine statins.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation, a pharmaceutical composition and application thereof. The traditional Chinese medicine composition consists of bulbus fritillariae cirrhosae, kelp, thunberg fritillary bulb, turmeric, endothelium corneum gigeriae galli, raw hawthorn and selfheal. According to the application, the bulbus fritillariae cirrhosae and the bulbus fritillariae thunbergii are compatible to synergistically exert the effects of reducing phlegm and resolving The endothelium corneum gigeriae galli and the raw hawthorn have the effect of removing food retention, the selfheal has the effect of clearing liver and removing stasis, and all the medicines are combined to achieve the effects of reducing phlegm, removing blood stasis, softening hard mass and eliminating diseases. Experiments show that the traditional Chinese medicine composition can significantly improve the liver function of Wilson disease model mice, reduce collagen deposition of liver tissues, down-regulate fibrosis markers and inhibit activation of hepatic stellate cells.

The invention discloses an AvHel31B target gene for preventing and treating tetranychus crataegus, application of the AvHel31B target gene, dsRNA synthesized by the AvHel31B target gene and application of the dsRNA. The nucleotide sequence of the AvHel31B target gene is as shown in SEQ ID NO. 1, and the nucleotide sequence of the dsRNA is as shown in SEQ ID NO. 2; after the AvHel31B is interfered, the egg laying amount of the tetranychus crataegus is obviously reduced, and the survival rate is obviously influenced due to abnormal growth and development, so that the prevention and treatment aim is achieved; the method is convenient to operate, good in effectiveness and sensitivity and high in insecticidal efficiency, has the advantages of being environmentally friendly and the like, and has a good application prospect.

The invention relates to the technical field of animal husbandry and veterinary medicine, and discloses a compound preparation for preventing and treating ruminant rumen acidosis, and the compound preparation comprises the following raw materials by mass: 50.0-70.0% of sodium bicarbonate; 10.0% to 20.0% of magnesium oxide; 0.5% to 2.0% of resveratrol; 0.5% to 1.5% of taurine; 1.0%-3.0% of a hawthorn extract; 1.0% to 5.0% of a bacillus subtilis agent; 0.5%-1.5% of a berberine extract; 1.0%-3.0% of compound vitamin B; 1.0%-3.0% of astragalus polysaccharide; 5.0% to 10.0% of saccharomyces cerevisiae; according to the formula, gastric acid is rapidly neutralized through the alkaline buffer agent, rumen micro-ecological balance is rebuilt in combination with the probiotic flora, excessive proliferation of acid-producing bacteria is inhibited by utilizing the plant extract, damaged mucous membranes are repaired, and the disease resistance of a body is improved in cooperation with the immunopotentiator; a multi-dimensional synergistic effect system of acid-base regulation, flora repair, mucous membrane protection and immune enhancement is formed, and the problems that a traditional scheme is single in action dimension, insufficient in curative effect durability and incapable of coping with a complex pathological process are solved.

This invention relates to the field of biomedical technology, specifically to a topical composition for improving acne and its application. The topical composition is made from pharmaceutical raw materials including a first component, a second component, and a third component. The first component comprises 25-35 parts of *Ampelopsis japonica*, 25-35 parts of hawthorn, 25-35 parts of *Salvia miltiorrhiza*, 13-17 parts of gardenia, and 8-12 parts of *Bletilla striata*. The second component comprises 25-35 parts of mother-of-pearl, 13-17 parts of tribulus terrestris, and 8-12 parts of safflower. The third component comprises 13-17 parts of raw rhubarb, 8-12 parts of gallnut, 8-12 parts of turmeric, 3-7 parts of *Ganoderma lucidum*, and 3-7 parts of asparagus. This invention also provides a topical composition consisting of the first, second, or third component alone. The topical composition of this invention has dual effects of inhibiting *Propionibacterium acnes* and anti-inflammatory properties, and can be further prepared into cosmetics or pharmaceuticals for the prevention, relief, and treatment of various types of acne and the improvement of acne scars. Clinical trials have shown significant effects, high safety, and promising application prospects.

The invention discloses a plant extract composition for enhancing disease resistance of fish fries and application of the plant extract composition, and belongs to the technical field of aquaculture. The plant extract composition for enhancing the disease resistance of the fry is prepared from the following raw materials in parts by mass: 10 to 20 parts of macleaya cordata extract, 15 to 25 parts of gallnut extract, 10 to 20 parts of red-knees herb extract, 5 to 15 parts of hawthorn fruit extract and 5 to 10 parts of liquorice root extract. According to the plant extract composition provided by the invention, five extracts of macleaya cordata, gallnut, red-knees herb, hawthorn and liquorice are scientifically compounded, so that a remarkable synergistic interaction effect is generated, the non-specific immune function of fry can be effectively regulated, and the disease resistance and stress resistance of the fry are improved. Especially for pelteobagrus fulvidraco fries, the composition can significantly repair and protect fragile intestinal tract and gill mucosa tissues of the pelteobagrus fulvidraco fries while efficiently preventing and controlling bacterial and parasite infection.

The invention provides a traditional Chinese medicine preparation for preventing and treating insomnia and depression and a production method thereof, and belongs to the field of traditional Chinese medicine preparations, and the traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 3-5 parts of gastrodia elata, 5-10 parts of spina date seed, 5-10 parts of codonopsis pilosula, 5-10 parts of bighead atractylodes rhizome, 5-10 parts of poria cocos, 5-10 parts of radix rehmanniae and 5-10 parts of hawthorn. According to the traditional Chinese medicine, all the medicines are matched with one another, complement each other, nourish blood, tranquilize nerves, calm liver wind, activate blood, cool blood, induce diuresis, remove dampness, tonify spleen, treat both symptoms and root causes, and protect the important organ function of the body.

The invention discloses a traditional Chinese medicine composition for treating functional dyspepsia with brain-intestine peptide disorder. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20-40 parts of codonopsis pilosula, 10-20 parts of poria cocos, 10-20 parts of Chinese yam, 5-15 parts of fingered citron, 10-15 parts of hawthorn and 2-8 parts of liquorice. Animal experiments prove that the traditional Chinese medicine composition disclosed by the invention has a remarkable effect in the aspect of treating functional dyspepsia with brain-intestine peptide disorder.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating pulmonary nodules and a preparation method of the traditional Chinese medicine composition. The active component is prepared from the following raw materials in parts by mass: 30 to 36 parts of rhizoma fagopyri dibotryis, 16 to 20 parts of herba hedyotidis diffusae, 12 to 14 parts of rhizoma arisaematis, 8 to 10 parts of bulbus fritillariae thunbergii, 6 to 9 parts of rhizoma corydalis, 6 to 7 parts of rhizoma polygonati, 1 to 2 parts of rhizoma dioscoreae, 4 to 5 parts of poria cocos, 3 to 4 parts of radix angelicae and 1 to 2 parts of liquorice root; in the preparation process, a synergistic accelerant is added, and the synergistic accelerant is prepared by mixing honeysuckle, burdock, hawthorn and seaweed according to a certain proportion and then performing enzymolysis; the combination of the four medicines can guide and improve the overall efficacy by optimizing the immune microenvironment, multi-target immune regulation and other ways, and ensures the pertinence and effectiveness of the traditional Chinese medicine composition for treating pulmonary nodules.

This invention relates to the field of traditional Chinese medicine composition technology, and in particular to a traditional Chinese medicine composition for treating type 2 diabetes and its preparation method. The raw materials consist of Coptis chinensis, hawthorn, Polygonatum sibiricum, Salvia miltiorrhiza, Lycium barbarum, Atractylodes lancea, dried ginger, mulberry leaf, and silkworm excrement, with a mass ratio of 3:6:6:3:2:3:3:3:3. This traditional Chinese medicine composition can not only improve blood glucose indicators, but also adjust the internal environment of the body and improve the patient's metabolic level by exerting the functions of invigorating qi and nourishing yin, promoting blood circulation and removing blood stasis, thereby achieving the purpose of lowering and stabilizing blood glucose. It can treat both the symptoms and the root cause of glucose and lipid metabolism disorders.

The invention discloses an application of hawthorn glycosyl transferase and related biological materials in biosynthesis of rhamnoside vitexin. The invention firstly discloses any one of the following proteins: A1) a protein consisting of an amino acid sequence as shown in a sequence 2; a2) a fusion protein obtained by connecting the N end or / and C end of the protein as shown in the sequence 2 with a protein tag. The invention further discloses the protein related biological material and application thereof. The key glycosyl transferase gene CpCGT for biosynthesis of rhamnovitexin is obtained from hawthorn for the first time, and it is proved that the protein CpCGT coded by the key glycosyl transferase gene CpCGT can catalyze 2-hydroxynaringenin to form a precursor compound 2-hydroxynaringenin-C-glucoside of rhamnovitexin. And the method has important significance on biosynthesis and heterologous production of rhamnoside vitexin.

The invention relates to the field of plant extracts, in particular to application of a hawthorn extract in preparation of a medicine for treating gall-stone. Dry hawthorn pulp is smashed, heated and extracted with an ethanol solution, filtered, concentrated and dried to obtain the hawthorn extract, the hawthorn extract can inhibit and treat gall-stone, the content of total bile acid (TBA) in a guinea pig gall-stone model is increased, the content of Ca < 2 + > and TBIL (total bilirubin) is reduced, and all indexes return to the normal level. In addition, the composite extract prepared by the invention and the combination of the composite extract and the hawthorn extract can effectively inhibit and treat gall-stone.

The present application provides a kind of containing sanqi polysaccharide composition, preparation method and its application, belong to plant extraction technical field.The present application containing sanqi polysaccharide composition includes: composite polysaccharide extract, salvia miltiorrhiza extract, kudzu extract and red yeast powder.The present application is crushed after sanqi, angelica, rehmannia glutinosa, ginseng, platycodon grandiflorum and hawthorn is prepared composite polysaccharide extract by removing fat, water extraction, enzymolysis, alcohol precipitation, drying and other steps, salvia miltiorrhiza, kudzu and 70-80% ethanol are mixed to extract, and salvia miltiorrhiza and kudzu extract are dried;Composite polysaccharide extract, salvia miltiorrhiza and kudzu extract and red yeast powder are mixed to obtain sanqi polysaccharide composition.The composite polysaccharide extract prepared by the present application has high hypolipidemic activity, can significantly reduce the body weight and liver weight of hyperlipidemic rats, will not inhibit the normal feeding of hyperlipidemic rats, can improve the HDL-C level in serum, reduce the TC content, TG content and LDL-C content in serum.

The invention relates to the technical field of medicinal breeding of special insects, in particular to a method for improving digestion and absorption efficiency and antibacterial immune components of maggots, and the method comprises the following steps: preparing a fish-hawthorn-astragalus membranaceus fermented feed; continuous three generations of directional stress screening are carried out, offspring is used as next generation provenance, and a target population is obtained; the three continuous generations of directional stress screening are performed according to the following modes: first-generation screening: feeding larvae with fermented feed, and applying high-protein stress; the larvae are fed with fermented feed added with astragaloside, low-temperature stress is applied, and individuals with the immune globulin IMPI content larger than or equal to 600 mu g / g are screened; and third-generation screening: feeding the larvae with fermented feed, and applying high-protein and low-temperature composite stress. The fish-hawthorn-astragalus membranaceus fermented feed is prepared in combination with continuous three-generation directional stress screening, so that the effects of activating intestinal protease of maggots to improve the digestion efficiency, promoting immune cell differentiation to accumulate immune components, enhancing intestinal flora regulation and enhancing the digestion and immune synthesis capability are achieved.

This invention relates to the field of traditional Chinese medicine (TCM) technology, and particularly to the application of TCM compositions in the preparation of drugs for the prevention and treatment of nephrotic syndrome. The TCM composition of this invention includes *Sedum sarmentosum*, seaweed, oyster shell, hawthorn, *Siegesbeckia orientalis*, *Schisandra chinensis*, and *Polygonum cuspidatum*. This invention has found that this composition can significantly reduce urinary protein levels, regulate serum ALB, Cr, and BUN levels, improve renal function, and has a good therapeutic effect on nephrotic syndrome. Moreover, this TCM composition is an existing prepared Chinese medicine, safe to use, and its preparation method is simple, rapid, efficient, and easy to operate. The prepared mixtures, tablets, capsules, and micro-pellets are easy to carry and convenient to take.

The invention relates to a multi-component synergistic breeding hen hatching accelerant and a preparation process thereof, and belongs to the technical field of feed additives. The accelerant comprises the following components in parts by weight: 5-10 parts of a composite plant extract which is extracted from herba epimedii, hawthorn, astragalus membranaceus and liquorice according to a ratio of (2-3): (1-2): (1-2): (1-1.5), 1-4 parts of a probiotic preparation containing bacillus subtilis, saccharomycetes and lactic acid bacteria, 0.1-0.3 part of vitamin D3, 0.2-0.5 part of guanidinoacetic acid, 0.2-0.5 part of xylooligosaccharide and 70-90 parts of a carrier. The preparation process comprises the following steps: ultrasonically extracting the plant extract, concentrating under reduced pressure, embedding the probiotics by trehalose and beta-glucan microcapsules, mixing all the components, coating by melt hydrogenated palm oil, freeze-drying and crushing, and the like. Through the synergistic effect of multiple components, the hatching rate of breeding hens and the quality of chicks can be remarkably improved, and the feed is high in safety, high in stability and suitable for large-scale breeding hens.

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for reducing lipid, a preparation method and application. The traditional Chinese medicine composition for reducing lipid provided by the application comprises a lipid-reducing core component and an auxiliary component. The lipid-reducing core component is composed of Camellia pitardii and Dalbergia odorifera. The auxiliary component comprises hawthorn and Salvia miltiorrhiza. The traditional Chinese medicine composition for reducing lipid provided by the application has a simple composition, can significantly improve the blood lipid indexes of a hyperlipidemia model animal, can reduce the body weight of the model animal, and can reduce the expression amount of the inflammatory factor TNF-alpha of the hyperlipidemia model animal.