74 results about "Crataegus monogyna" patented technology

The invention discloses hawthorn leaf pectic polysaccharide with lipid-lowering activity and a preparation method and application thereof, and belongs to a preparation method of plant polysaccharide, the preparation method comprises the following steps: refluxing hawthorn leaves with ethanol, discarding monosaccharide and small molecule compounds, refluxing with hot water to extract medicinal materials, removing protein through an enzymolysis method and a Sevage reagent method, decolorizing with polyamide resin, and drying to obtain the hawthorn leaf pectic polysaccharide with lipid-lowering activity. The crude polysaccharide is separated through DEAE-52 column chromatography, and finally, the crude polysaccharide is further purified through Sephadex G-100, so that the uniform purified polysaccharide is obtained. Tests on pancreatic lipase inhibition, taurocholate binding capacity and glycocholate binding rate show that the compound has remarkable lipid-lowering activity and is expected to become a potential natural lipid-lowering preparation.

The invention belongs to the technical field of medicine, and provides a traditional Chinese medicine composition, a traditional Chinese medicine preparation and application thereof, and the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-30 parts of astragalus membranaceus, 20-30 parts of phaseolus calcaratus, 5-10 parts of radix rehmanniae, 10-20 parts of endothelium corneum gigeriae galli, 10-15 parts of hawthorn and 5-20 parts of fingered citron. The traditional Chinese medicine composition disclosed by the invention has an exact curative effect on improving the liver function, total bile acid metabolism and the like of intrahepatic cholestasis in the gestation period. Clinical, animal and cell test results show that the traditional Chinese medicine composition can effectively improve symptoms and signs of intrahepatic cholestasis in the gestation period.

The invention discloses an Srp54k target gene for preventing and treating tetranychus crataegus and tetranychus urticae and application of the Srp54k target gene, dsRNA synthesized by the Srp54k target gene and application of the dsRNA. The nucleotide sequences of the Srp54k target gene are shown as SEQ ID NO.1 and SEQ ID NO.2, and the nucleotide sequences of the dsRNA are shown as SEQ ID NO.3 and SEQ ID NO.4; after SRP54K is interfered, eggs of tetranychus crataegi and tetranychus urticae are caused, the survival rate is obviously influenced, and the prevention and treatment aim is achieved; the method is convenient to operate, good in effectiveness and sensitivity and high in insecticidal efficiency, has the advantages of being environmentally friendly and the like, and has a good application prospect.

The invention provides Yixinshu granules and a preparation method thereof, and belongs to the technical field of medicines. Ginseng, astragalus membranaceus, radix ophiopogonis, hawthorn, salvia miltiorrhiza, schisandra chinensis and ligusticum wallichii are subjected to immobilized enzyme enzymolysis and enzyme-assisted fermentation, a product is filtered, an ionic liquid solid-phase extraction agent is added, carbon dioxide is introduced, stirring adsorption, filtering, solid desorption and drying are conducted, extract is prepared, the extract, maltodextrin and stevioside are evenly mixed, granulation and drying are conducted, and the Yixinshu granules are prepared. The Yixinshu granules prepared by the invention are simple in preparation method, wide in raw material source, easy to realize industrial application, relatively low in cost and high in patient compliance, have the characteristics of quick dissolution, quick absorption, high bioavailability and the like, have the effects of tonifying qi and restoring pulse, promoting blood circulation to remove blood stasis and nourishing yin and promoting salivation, and have a wide application prospect.

The invention discloses a method for assisting hawthorn breeding based on phenotypic omics, and relates to the technical field of phenotypic omics assisted hawthorn breeding. Comprising the following steps: S1, acquiring phenotypic data of normally growing hawthorns by using a high-throughput imaging system and a phenotypic analysis system, and detecting and analyzing various characters of the hawthorns; s2, establishing a hawthorn multi-dimensional phenotypic group database, and obtaining hawthorn breeding key character quantitative indexes; s3, constructing a phenotype-genotype correlation model according to the obtained hawthorn breeding key character quantitative indexes, and mining new functional genes to realize early prediction of breeding; and S4, creating a phenotype exponential weighting algorithm for parent matching. The method for assisting hawthorn breeding based on phenotypic omics is established, the problems of long hawthorn breeding period and high cost are solved, and the hawthorn breeding efficiency is effectively improved.

The invention relates to the technical field of traditional Chinese medicines, in particular to application of a traditional Chinese medicine composition in preparation of medicines for preventing and treating hypertension. The traditional Chinese medicine composition comprises sedum sarmentosum, seaweed, oyster, hawthorn, herba siegesbeckiae, schisandra chinensis and polygonum cuspidatum. The composition is found to be capable of remarkably inhibiting a renin-angiotensin-aldosterone system, regulating vascular active factors, relaxing vascular smooth muscles, protecting vascular endothelial functions, reducing heart left ventricular hypertrophy and effectively reducing systolic pressure and diastolic pressure. The traditional Chinese medicine composition is an existing Chinese patent medicine, medication is safe, and the preparation method is simple, rapid, efficient and easy to operate. The prepared mixture, tablet, capsule, pellet and the like are convenient to carry and take.

The invention discloses a composition for improving adverse effects of chemotherapy as well as a preparation method, application and a product of the composition, and particularly relates to the technical field of medicines. The composition comprises the following raw materials: tortoise, soft-shelled turtle, antler, sea cucumber, fructus amomi, pericarpium citri reticulatae and hawthorn. Alkaline protease and flavourzyme are adopted for enzymolysis, and the obtained composition can remarkably reduce the tumor volume of tumor-bearing animals, increase the bone marrow DNA content of chemotherapy animals and remarkably increase the number of white blood cells and the number of red blood cells in peripheral blood of the chemotherapy animals. The composition disclosed by the invention is used for preparing related products for improving the adverse effects of chemotherapy, and the prepared products are easy to absorb and have a remarkable improvement effect on the adverse effects of chemotherapy.

The invention discloses a fertilizer for promoting and improving the immunity of plants and a preparation method, and relates to the field of fertilizers. The preparation method comprises the following steps: mixing, smashing and grinding earthworms, eucalyptus leaves, wheat leaves and hawthorn leaves, putting into an ethanol solution, oscillating for 20-24 hours in a shaking table, and centrifugally filtering to obtain an active extracting solution; adding a sodium alginate solution into the suspended bacteria solution and the active extracting solution, and slowly adding carboxymethyl chitosan and a calcium chloride solution; and preparing. According to the invention, the plant growth-promoting rhizobacteria are fixed in the composite hydrogel, and the composite hydrogel can promote colonization of strains at plant root tips and lateral roots so as to regulate deposition of endothelial cell suberite, optimize mineral nutrition balance and abiotic stress response of plants and improve accumulation of auxin at the root tips; meanwhile, an active extracting solution is added into the composite hydrogel, immune response can be activated, and the metabolic activity and antioxidant activity of plants are greatly improved in combination with extracts of other substances.

The invention discloses a detection method of a medicine for treating apoplexy sequela, and relates to the technical field of traditional Chinese medicinal material detection. The capsule disclosed by the invention comprises the following components: ginseng, deer-horn glue, tortoise shell, fructus lycii, turtle shell, leech, ligusticum wallichii, rheum officinale, hawthorn, earthworm, scorpio, bungarus parvus, gastrodia elata, stiff silkworm and borneol. During identification, microscopic identification and thin-layer chromatography identification are adopted, the gastrodia elata and the hawthorn are identified by the thin-layer chromatography, and the microscopic identification is used for identifying a capsule finished product; the aims of accurately detecting the ginseng and snake hemiplegia capsule and reducing the large influence on the detection result due to the change of different temperature and humidity in the environment are achieved.

The invention relates to the technical field of pest mite biopesticide prevention and control, in particular to a hawthorn tetranychid mite prevention and control agent with CGG as a carrier and a preparation device.The hawthorn tetranychid mite prevention and control agent with CGG as the carrier comprises a base, a metering pump, a supporting table, a batching structure, a defoaming structure and a mixing structure, and defoaming barrels are symmetrically and fixedly connected to one side of the top of the base; the other side of the top of the base is fixedly connected with a mixing barrel, the top of the partition plate is symmetrically and fixedly connected with metering pumps, the two sides of the base are fixedly connected with supporting tables, the tops of the supporting tables are fixedly connected with a batching barrel, a batching structure used for batching is installed in the batching barrel, and a defoaming structure used for defoaming is installed in a supporting plate. The hawthorn tetranychus mite prevention and control agent with the CGG as the carrier and the preparation device of the hawthorn tetranychus mite prevention and control agent have the advantages that the prevention and control effect of hawthorn tetranychus mites is improved, efficient automatic production is achieved, efficient defoaming treatment is achieved, and cleaning and maintenance are easy.

The invention relates to the technical field of microbial fermentation engineering, and particularly discloses natto red yeast rice herb bean flour and a preparation method thereof. The preparation method comprises the following steps: respectively activating specifically preserved bacillus natto and monascus to obtain secondary seed solutions; inoculating the two seed solutions into a solid-state fermentation culture medium for co-fermentation; and inactivating, drying and crushing the fermentation product to obtain a finished product. The solid-state fermentation culture medium is prepared by compounding a bean matrix (soybeans, black beans or chickpeas) and herb tea components (roses, lotus leaves, chrysanthemums, mulberry leaves, haws, cassia seeds and the like). Through the synergistic effect of the bacillus natto and the monascus, nattokinase and monacolin K are efficiently enriched in a single fermentation system at the same time, conversion of soy isoflavone to a high-bioavailability aglycone type is remarkably promoted, and the obtained product has multiple health-care functions of thrombolysis, lipid reduction, efficient absorption and the like.

The invention discloses a hawthorn disease identification method based on a deep convolutional neural network and a disease image, and is applied to the technical field of hawthorn disease prevention and control. Comprising the following steps: collecting hawthorn disease image data as a training sample, distinguishing healthy plants and disease plants in a manual labeling manner, and refining to disease categories and disease degrees; carrying out data cleaning, data enhancement, data set expansion and normalization processing, constructing and training a deep convolutional neural network model for disease identification, and testing the detection performance by adopting a multi-dimensional evaluation index; and acquiring an image of a to-be-detected hawthorn plant, and inputting the image into the hawthorn disease identification model for real-time identification. According to the method, the pre-trained deep convolutional neural model is combined with the multi-scale data enhancement strategy and the adaptive transfer learning technology, the hawthorn disease intelligent identification system for the complex plant image scene is constructed, high-precision identification and automatic efficient detection of multiple diseases of hawthorns can be realized, and the real-time monitoring requirement of an orchard is met.

The invention relates to the field of natural products, in particular to active hawthorn protein for inhibiting a bacterial biofilm and a preparation method and application of the active hawthorn protein for inhibiting the bacterial biofilm, and the active hawthorn protein for inhibiting the bacterial biofilm comprises antibacterial hawthorn protein and a multi-element modification layer compounded with the antibacterial hawthorn protein; the modification layer is obtained by compounding polysaccharide and amine components. The antibacterial protein is extracted from hawthorn fruits, and the surface of the antibacterial protein is subjected to surface modification through polysaccharides and natural amines, so that the purpose of improving the acid resistance of the hawthorn protein is achieved, and the antibacterial protein can stably act on a bacterial biofilm in an acidic microenvironment. Meanwhile, after surface modification, the affinity adhesion capacity of hawthorn protein and a biological membrane can be improved, and the interaction between a composite structure and a bacterial biological membrane structure is enhanced, so that the penetrating effect is achieved, and the antibacterial effect is improved.

The invention discloses a preparation method of a pharmaceutical composition for treating skin itching, belonging to the field of plant extraction of effective ingredients, and comprising the following steps: 1) extracting total Centella asiatica saponins from Centella asiatica, wherein the total Centella asiatica saponins contain more than 80% by weight of saponin components; 2) extracting from a medicinal material of hawthorn leaves a refined extract containing more than 80% by weight of flavonoid components to obtain total flavonoids of hawthorn leaves; 3) extracting from a medicinal material of white peony acuminata a refined extract containing more than 80% by weight of monoterpene glycoside components to obtain total glycosides of white peony acuminata; 4) mixing 0.5-3 parts of total Centella asiatica saponins, 1 part of total flavonoids of hawthorn leaves, and 0.5-3 parts of total glycosides of white peony acuminata to prepare the pharmaceutical composition for treating skin itching.

The invention discloses a culture optimization method of brevibacillus laterosporus and application of brevibacillus laterosporus in inhibiting pathogenic bacteria of hawthorn, an LB liquid culture medium is adopted in the culture process, and the culture medium comprises the following components: 10 g / L peptone, 15 g / L sucrose and 10 g / L yeast powder; the initial pH of fermentation is 7-8, the culture temperature is 30-35 DEG C, the rotating speed is 180-200rpm, the culture time is 24-36 hours, and the inoculum size of the brevibacillus laterosporus CB-528 bacterial liquid is 3-5vol%, and finally obtaining the fermented bacterial liquid through fermentation. The zymophyte liquid prepared on the basis of the method can be used for preparing biopesticides for preventing and treating Chinese yam diseases. The fermentation process disclosed by the invention is simple to control, easy to operate and obvious in effect, and the thallus yield and the spore rate can be greatly improved under the fermentation process. The fermentation culture solution disclosed by the invention has the characteristics of high activity, high viable organism content and high spore rate, and can prolong the preservation time of a subsequent preparation and improve the drug effect stability of the preparation.

The invention discloses a method for simultaneously purifying triterpenoids, hawthorn flavonoids and hawthorn polysaccharides from hawthorn, which comprises the following steps: crushing a hawthorn medicinal material, extracting, performing macroporous resin graded adsorption, performing gradient elution, performing membrane separation and the like to respectively obtain hawthorn extracts rich in triterpenoids, hawthorn flavonoids and hawthorn polysaccharides. According to the method, hawthorn is used as a raw material, the extraction, separation and purification method is simple, the used solvent is green, pollution-free and low in cost, hawthorn extracts rich in triterpenoids, hawthorn flavonoids and hawthorn polysaccharides are respectively obtained through macroporous resin graded adsorption, gradient elution, membrane separation and other methods, the effects of squeezing to be dry, taking all hawthorn flavonoids and comprehensively utilizing hawthorn flavonoids are achieved, the utilization rate is high, and the method is suitable for industrial production. The utilization value of hawthorn is improved, and the application prospect is wide.

The invention provides a plant lactobacillus and application thereof. The first aspect of the invention provides the plant lactobacillus, the plant lactobacillus is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC NO.28495. The invention also provides a preparation method of the plant lactobacillus. According to the plant lactobacillus provided by the invention, the content of flavonoid compounds in a plant fermentation product can be increased by at least 10%, specifically, the content of isorhamnetin in a hippophae rhamnoides fermentation product can be increased to 7 times of that before fermentation, and the content of isorhamnetin in the hippophae rhamnoides fermentation product can be increased by at least 10%. The content of quercetin-3-O-sophorobiose-7-O-rhamnoside in a mulberry leaf fermentation product can be increased to 7.5 times that of the folium mori fermentation product before fermentation, the content of isorhamnetin-3-O-sophorobiose-7-O-rhamnoside in a hawthorn fermentation product can be increased to 1.1 times that of the hawthorn fermentation product before fermentation, and the method has the advantages of being low in cost, environmentally friendly, efficient and the like.

The invention discloses a formula and a preparation method of a stomach-invigorating parasite-expelling tablet for livestock. The parasite expelling tablet is formed by compounding and tabletting parasite expelling core enteric particles A and stomach invigorating and relieving quick-release particles B. The particles A contain praziquantel and levamisole or salts thereof, and are coated with enteric materials, so that the parasite expelling activity is limited in gastric segment release and is quickly released in intestinal segment; the particles B contain a cortex meliae extract, a fructus quisqualis extract, pericarpium citri reticulatae, fried malt and fructus crataegi, are compounded with mucous membrane protection or adsorption stimulation components such as sodium alginate / pectin / montmorillonite and the like, and are subjected to post-treatment adsorption through essence, so that the taste covering stability is improved. The preparation method comprises the following steps: plant extraction, wet granulation in two ways, enteric coating of particles A, essence post-treatment of particles B, and compounding, lubricating and tabletting. According to the scheme, the insect expelling effect is guaranteed, gastrointestinal stimulation is reduced, the voluntary ingestion rate and administration compliance are improved, and the composition is suitable for dogs, cats and livestock to expel insects by oral administration.

The invention discloses an extraction method of hawthorn exosomes and application of the hawthorn exosomes in treatment of DSS-induced colitis, and belongs to the technical field of plant exosomes. The extraction method comprises the steps of raw material treatment, differential centrifugation, membrane filtration, ultracentrifugation enrichment, density gradient purification and desugaring refining, and the high-purity crataegus pinnatifida exosome with the capsule-shaped structure can be obtained. The hawthorn exosome intervenes DSS-induced colitis through preventive intragastric administration (25-50 mg / kg / d), the disease activity index (DAI) can be reduced to 2 or below, the expression quantity of colon tissue TNF-alpha is recovered to the normal level, the IL-1beta inhibition effect is superior to that of a hawthorn extract, and the curative effect is remarkably superior to that of plant exosomes such as rhizoma curcumae longae, tea leaves and black tea. The process is standardized, the curative effect is definite, and a new scheme is provided for colitis treatment.

This invention discloses a composition and its preparation method for treating human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN), belonging to the field of traditional Chinese medicine technology. The formula consists of 6-15 parts of American cockroach, 5-11 parts of hawthorn, 5-11 parts of chicory, 3-9 parts of *Scutellaria baicalensis*, 8-20 parts of *Sophora flavescens*, and 6-15 parts of *Cnidium monnieri*, and also contains 0.01-1 parts by weight of toad venom. The dosage form is one or more of the following: external gel, rinse, foam, suppository, and film preparation. It has high safety and is suitable for HPV infection and CIN changes, solving the problem of poor efficacy in existing treatments.

The present invention relates to the technical field of traditional Chinese medicine, and in particular to an antibacterial Chinese medicine composition and its application. The Chinese medicine composition of the present invention includes 1-10 parts of sappan wood extract, 1-3 parts of sanguisorba officinalis charcoal extract, 1-10 parts of rose extract, 1-5 parts of blood-seeing shrew extract, 1-5 parts of madder charcoal extract, 1-5 parts of hawthorn extract, and 1-5 parts of stir-fried tribulus extract. The Chinese medicine composition has a very significant inhibitory effect on Acinetobacter baumannii, and can play a synergistic effect with antibiotics such as imipenem and minocycline, significantly improving the therapeutic effect of Acinetobacter baumannii infection.

The invention belongs to the technical field of biological medicines, and particularly discloses a cardiomyopeptide freeze-dried composition as well as a preparation method and application thereof. The cardiomyopeptide freeze-dried composition comprises the following components in parts by mass: 12-15 parts of cardiomyopeptide, 8-11 parts of radix ophiopogonis, 6-8 parts of schisandra chinensis, 3-5 parts of hawthorn, 1-2 parts of spirulina powder and 1-2 parts of blueberry powder. The invention discloses a cardiomyopeptide freeze-dried composition and a preparation method and application thereof. The cardiomyopeptide freeze-dried composition is high in activity and good in stability, can relieve myocardial damage and can be applied to preparation of drugs for nourishing myocardium and protecting blood vessels.

The application provides a blood-activating and stasis-removing medicinal composition containing fermented douchi and a preparation method thereof, belongs to the technical field of biological medicine, and the medicinal composition comprises fermented douchi, drynaria extract, extract of pereskia aculeata, tanshinone II A, notoginsenoside R1, ligustrazine, rhodioside, total flavones of hawthorn leaves and total flavones of mulberry leaves. The fermented douchi is prepared from soybeans and black beans through fermentation by bacillus subtilis and bacillus coagulans. The drynaria extract is prepared from drynaria powder through common enzymolysis by cellulase, chitinase and beta-glucanase, extraction by a two-phase solvent, and purification by a dextran gel column. The extract of pereskia aculeata is prepared from pereskia aculeata powder through common enzymolysis by pectinase, cellulase and xylanase, common enzymolysis by bromelain and subtilisin, and purification by a macroporous adsorption resin column. The medicinal components are prepared in a specific proportion to relieve blood stasis from two dimensions of "improving blood flow dynamics + preventing thrombus formation".

The present application provides a kind of shrimp breeding phagostimulant and its preparation method.The phagostimulant comprises the following components by weight: 10-30 parts of schisandra chinensis, 150-200 parts of hawthorn powder microcapsule, 1-10 parts of baking soda, and 0.1-1 part of phagostimulant aid.The phagostimulant prepared by the present application, when applied to the growth test of grass shrimp with feed, can increase the yield per mu of grass shrimp by 127.6%-159.2%, and the growth rate, feeding rate and survival rate are all significantly better than conventional aquaculture, and no stress, disease and water ecological imbalance of shrimp body are caused during the aquaculture process, which meets the non-polluting fishery drug standard, and the effect is stable and reliable when used in different aquaculture areas, with strong adaptability.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating atherosclerosis and a preparation method thereof. The traditional Chinese medicine composition for treating atherosclerosis is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix astragali seu hedysari, 7 to 10 parts of radix notoginseng, 10 to 20 parts of poria cocos, 5 to 15 parts of lotus leaves, 10 to 15 parts of raw fructus crataegi, 10 to 20 parts of radix salviae miltiorrhizae, 10 to 15 parts of radix angelicae sinensis and 2 to 10 parts of ramulus cinnamomi. The traditional Chinese medicine composition can intervene in the atherosclerosis process through multiple ways of adjusting the blood fat level, improving aorta pathological injury, inhibiting inflammatory response, increasing intestinal flora diversity and the like, and the comprehensive treatment effect of the traditional Chinese medicine composition is equivalent to that of clinical conventional medicine statins.

The invention discloses a nondestructive testing method and device for the water content of hawthorn based on hyperspectral imaging, and relates to the technical field of detection and analysis of the water content of the hawthorn, and the method comprises the following steps: collecting original spectral data of a hawthorn sample; performing FD processing on the original spectral data to obtain spectral data after FD processing; a WT-SR algorithm is adopted, dimension reduction processing is carried out on the spectrum data after FD processing, and key characteristic variables are obtained; and inputting the key characteristic variables into a pre-trained SVR model to obtain a hawthorn water content prediction result of the hawthorn sample. According to the invention, nondestructive detection of the water content of hawthorn can be realized, and the detection precision and efficiency are ensured.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation, a pharmaceutical composition and application thereof. The traditional Chinese medicine composition consists of bulbus fritillariae cirrhosae, kelp, thunberg fritillary bulb, turmeric, endothelium corneum gigeriae galli, raw hawthorn and selfheal. According to the application, the bulbus fritillariae cirrhosae and the bulbus fritillariae thunbergii are compatible to synergistically exert the effects of reducing phlegm and resolving The endothelium corneum gigeriae galli and the raw hawthorn have the effect of removing food retention, the selfheal has the effect of clearing liver and removing stasis, and all the medicines are combined to achieve the effects of reducing phlegm, removing blood stasis, softening hard mass and eliminating diseases. Experiments show that the traditional Chinese medicine composition can significantly improve the liver function of Wilson disease model mice, reduce collagen deposition of liver tissues, down-regulate fibrosis markers and inhibit activation of hepatic stellate cells.

The invention discloses a fresh water ecdysis regulator for penaeus vannamei as well as a preparation method and application of the fresh water ecdysis regulator. The fresh water ecdysis regulator for the penaeus vannamei is prepared from the following raw materials in parts by weight: 2-5 parts of calcium lactate, 0.01-0.02 part of vitamin C, 0.01-0.02 part of vitamin E, 4-6 parts of magnesium sulfate, 0.2-0.4 part of arginine, 5-10 parts of cyanotis arachnoidea, 6-8 parts of hawthorn, 5-10 parts of yeast powder, 10-20 parts of brown sugar, 5-8 parts of gynostemma pentaphyllum and 40-60 parts of rare earth. The molting regulator for freshwater aquaculture of the penaeus vannamei can promote molting of the penaeus vannamei by selecting the raw materials and dosage, solves the problem that the penaeus vannamei grows slowly in a freshwater aquaculture environment, is beneficial to reducing the morbidity of the penaeus vannamei and improving the survival rate and the aquaculture yield of the penaeus vannamei, and has a wide application prospect. The method has important scientific significance and practical application value for freshwater aquaculture of the penaeus vannamei boone.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating skin diseases and application thereof. The traditional Chinese medicine composition for treating skin diseases is further optimized on the basis of water nourishing and heart-fire clearing drink, takes kidney nourishing, heart-fire clearing, food retention removing and stagnation removing as a core treatment rule, and is prepared from radix rehmanniae, fructus gardeniae, hawthorn, medicated leaven, scutellaria baicalensis, lophatherum gracile, fructus aurantii, uncaria rhynchophylla, purslane, honeysuckle, cortex dictamni and areca catechu. The traditional Chinese medicine composition is few in medicine flavor, good in taste, fast in effect taking, high in safety and better in curative effect, and a treatment scheme is provided for patients with atopic dermatitis.

The invention discloses an AvHel31B target gene for preventing and treating tetranychus crataegus, application of the AvHel31B target gene, dsRNA synthesized by the AvHel31B target gene and application of the dsRNA. The nucleotide sequence of the AvHel31B target gene is as shown in SEQ ID NO. 1, and the nucleotide sequence of the dsRNA is as shown in SEQ ID NO. 2; after the AvHel31B is interfered, the egg laying amount of the tetranychus crataegus is obviously reduced, and the survival rate is obviously influenced due to abnormal growth and development, so that the prevention and treatment aim is achieved; the method is convenient to operate, good in effectiveness and sensitivity and high in insecticidal efficiency, has the advantages of being environmentally friendly and the like, and has a good application prospect.