1001 results about "Chinese patent" patented technology

The invention discloses a nitrate molten salt heat transferring and reserving medium and a preparation method and application thereof. The nitrate molten salt heat transferring and reserving medium is prepared with 5 to 40 percent of potassium nitrate, 5 to 25 percent of sodium nitrate, and 10 to 70 percent of calcium nitrate. The melting point of the nitrate molten salt heat transferring and reserving medium can be as low as 120 DEG C, and the upper limit of temperature for use can reach 550 DEG C, the nitrate molten salt heat transferring and reserving medium has a wide temperature scope of application, can work normally at the temperature scope of 180 DEG C to 550 DEG C, and has good thermal stability; the shortcoming of high melting point of binary nitrate molten salt system can be overcome, and the problem of instability caused by easy oxidative decomposition at high temperature of NaNO2 in the Chinese patent 200110027954.1 and ternary nitrate salt system can be solved, and the problems of corrosion and cost increase caused by the existing LiNO3 in the Chinese patent 00111406.9 and the American patent US007588694B1 can also be solved.

The invention provides a method for evaluating the quality of a Chinese patent medicament by using metabonomics. The method comprises the following steps: 1) according to the indication of traditional Chinese medicines, establishing a corresponding animal model and screening; 2) taking various of samples of the traditional Chinese medicines, and intervening a disease model animal by a corresponding route of administration; 3) collecting a corresponding biological sample and acquiring the metabolism finger-print of the sample; 4) carrying out pattern recognition on the metabolism fingerprints of a normal group and a disease group to obtain a metabolism biomarker group; 5) calculating the similarity of the metabolism biomarker group and the normal group in different administration groups, or carrying out PLS (partial least squares) regression analysis on differential endogenous metabolites, and observing the influence of medicament treatment on the endogenous metabolites; and 6) according to the similarity result or the result of the PLS regression analysis, evaluating the medicaments, wherein the more normal the control group trends to be, the better efficacy of the medicament is.

The discarded Chinese medicinal material residue produced from production of Chinese patent drug Mailuoning is used and producing steps are: coarse pulverizing, adding dried Chinese medicine residue to regulate water content, then adding cellulolytic bacteria to make stacked fermentation, sieving, finally adding regulator A and B according to a certain ratio to obtain a matrix. Finally, in the said matrix a certain quantity of seedling fertilizer and feishite can be added. Said invention also provides its application method and its advantages.

A method for automatically recognizing and manual assistance decimating scientific and technical terminology from Chinese patent documentations by a computer. According to the method, Chinese terminology which are possible to compose words are automatically recognized and decimated based on basic information of part-of-speech taggings by means based on rules on an point of view of Chinese phrase word-building, and the authenticity of the terminology is judged and determined based on manual assistance. The main steps include building various patent documentation bases based on fields; decimating repeat strings by using a special patent documentation base as a training corpus, syncopating and part-of-speech tagging repeat strings by using basic terminology, and checking repeatedly boundariesof repeat strings according Chinese accidence rules until the strings become receptible provision terminology. It is possible to affirm through manual assistance for further verifying the provision terminology.

The invention provides a Chinese patent medicinal preparation for treating constipation of the elderly, which consists of the following Chinese medicament raw materials by weight: 10 to 12 grams of rhubarb, 15 to 20 grams of hemp seeds, 10 to 15 grams of Achyranthes bidentata, 6 to 10 grams of platycodon grandiflorum, 6 to 10 grams of almond, 30 to 60 grams of Atractylodes macrocephaia, 10 to 15 grams of shelled cedar seed, 10 to 15 grams of cistanche deserticola, 10 to 15 grams of Chinese dodder seeds, 10 to 15 grams of medlar, 15 to 30 grams of black sesame seed, 15 to 30 grams of raw radix polygoni multiflori, 6 to 10 grams of fructus aurantii immaturus, 6 to 10 grams of Magnolia officinalis, 15 to 30 grams of radish seeds, 10 to 15 grams of aloe, 10 to 15 grams of cassia seed, 2 to 5 grams of senna leaf, 6 to 10 grams of Baikal skullcap root, 20 to 30 grams of Astragalus membranaceus and 10 to 15 grams of Chinese angelica. The various raw Chinese medicaments are crushed and processed into fine powder together; the fine powder is uniformly mixed; the mixture is subjected to ozone sterilization for 20 minutes; and the obtained product is prepared into capsules by the general method. The Chinese patent medicinal preparation is a pure Chinese medicinal preparation, can replenish essence and invigorate kidney, benefit vital energy and nourish yin, activate qi of intestines and internal organs, and relax bowel, and has good treatment effect, simple preparation method and low cost.

The invention provides a method for producing ultrahigh molecular weight polyethylene, which comprises the following steps of: adding a certain amount of external electron donors and a certain amount of hydrogen and performing ethylene homopolymerization or ethylene and alpha-olefin copolymerization in the presence of a catalyst described in Chinese patent CN02120861.1 to obtain an ultrahigh molecular weight polyethylene product.

The invention belongs to the technical field of electric system intelligent analysis and control, and particularly relates to an implementation method of a grid fault diagnosis system considering uncertain information. The implementation method of the grid fault diagnosis system considering the uncertain information is a grid fault diagnosis system practical method of an information theory and an expert system, is provided on the basis of a power system fault diagnosis method based on the information theory and the expert system, wherein the power system fault diagnosis method based on the information theory and the expert system is provided by a Chinese patent with a publication number of CN101661070A. The movement condition of reclosure and the movement condition of spare power automatic switching are added, and the practical requirement for applying the implementation method of the grid fault diagnosis system considering the uncertain information to an actual power system fault diagnosis system is met. The implementation method of the grid fault diagnosis system considering the uncertain information inherits an original method, and can further use movement information of the reclosure and movement information of the spare power automatic switching to give presentation of the movement condition of reclosure and presentation of the movement condition of the spare power automatic switching. Fault phase difference and fault types are used for reducing the scale of a protection set of possible movement, and complexity of a diagnosis process is reduced. The implementation method of the grid fault diagnosis system considering the uncertain information can serve as reference of a grid fault diagnosis system based on an algorithm of the same class.

The invention relates to a method for detecting illegally-added 42 chemicals in Chinese patent medicines and health care products simultaneously and belongs to the field of food safety. The detecting method disclosed by the invention is a high performance liquid chromatography-quadrupole/electrostatic field orbitrap high-resolution mass spectrum combined detecting method. According to the established method, the pretreatment process is simple and convenient, the analysis time is short, and the method is accurate, reliable, high in sensitivity and suitable for qualitative confirmation and quantitative detection of the illegally-added 42 chemicals in the Chinese patent medicines and the health care products and can be used for screening illegally-added drugs in the Chinese patent medicines and the health care products. Effective evidence is provided for control of quality of the health care products and fighting of illegal addition behaviors in the industry of health care products.

The invention discloses a GAP (good agricultural practices) cultivation technique for a leaf-harvesting ginkgo garden with red soil. By the GAP cultivation technique, the yield and quality of ginkgo can be effectively improved and the standardization and industrialization of leaf-harvesting ginkgo planting in red soil in south of China are promoted. The GAP cultivation technique comprises building and management technique of the leaf-harvesting ginkgo garden, methods of seed selection, seed planting stage, planting density and fertilization of the leaf-harvesting ginkgo, field management, disease and pest prevention and control method, ginkgo leaf harvesting stage and harvesting method, and methods for medicinal material field processing and storage. By adopting the technical scheme disclosed by the invention, high-quality raw medicinal material is provided for traditional Chinese medicine extract and Chinese patent drug pharmaceutical enterprises; and the GAP cultivation technique has very important effect of guaranteeing the safety, high efficiency, stability and controllable quality of the traditional Chinese medicine extracts and Chinese patent drugs.

The invention discloses a rapid screening method for illegally added 132 chemical drugs in Chinese patent medicines and health care products. The method adopts an Agilent Poroshell 120 EC-C18 chromatographic column for separation, and uses 0.1% formic acid water-acetonitrile as the mobile phase, uses electrospray ionization in a positive ion mode, and employs a pre-set multi-reaction monitoring model. The results show that the method has a good linear relationship with the 132 chemical drugs in a linear range, and the quantitation limit is 2microg/Kg-200microg/Kg; the recovery rate is 43.36%-114.92% under low, middle and high adding levels; and RSD is 0.4%-14.81%. The method has the characteristics of high sensitivity, strong specificity, simplicity and rapidity, and can be effectively used for simultaneous rapid screening of 132 illegally added chemical drugs in health care product and Chinese patent medicine samples.

The invention provides a detection method for illegal additives in weight-losing type Chinese patent medicines and health foods. A Q-Orbitrap high-resolution mass spectrometer is adopted and a Full MS Scan/dd-MS2 (Top N) scanning mode is carried out so that positive and negative ions are detected at the same time; the separation, high-precision first-grade mass spectrometric scanning and high-precision second-grade mass spectrometric scanning of analytes in a sample can be finished in an analyzing period to obtain accurate mass quantity and accurate fragment ion information; chromatography retention time, a first-grade mass spectrum and a second-grade mass spectrum of the sample are compared with those of a weight-losing type chemical component comparison product to determine that whether weight-losing type chemical medicines are doped into the sample or not; and rapid screening, confirmation and quantification can be carried out on a potential positive sample. The detection method has the advantages of high sensitivity, good selectivity, strong confirmation, simplicity and rapidness of operation and the like, can be used for accurately screening, has the sensitivity beyond comparison of traditional HPLC and low-resolution LC-MS, and can be used for identifying, confirming and quantitatively analyzing compounds in a single analysis period (12 minutes).

The invention discloses a method for continuously separating and purifying valine in fermentation liquor by using simulated moving bed chromatography, and belongs to the technical field of biological product processing. In the method, a simulated moving bed chromatography separating device suitable for the composition characteristic of valine fermentation liquor is designed, water is taken as a mobile phase, and the previously invented resin special for valine separation (disclosed in the Chinese patent 200910231735.4) is taken as a stationary phase. The method can completely remove impurities of alanine and leucine from the valine fermentation liquor, achieves product purity of over 99.7 percent to meet the medicinal standard, is suitable for continuous production, has higher recovery rate and production strength, and overcomes the defects of low purity, low efficiency, high pollution and the like in the conventional valine separation and purification process.

The invention relates to an oral administration prescription for hair blacking and baldness prevention and a preparation method and a using method thereof. The oral administration prescription consists of yin-nourishing, blood-tonifying, kidney-tonifying, qi-tonifying and blood-promoting traditional Chinese medicines, and is a formula of Chinese patent medicaments. The prescription and the compatibility thereof comprise the following medicaments by mass: 6 to 9 grams of donkey-hide glue, 4 to 8 grams of Chinese date, 3 to 6 grams of white paeony root, 5.5 to 15 grams of siberian solomonseal rhizome, 4 to 7 grams of Chinese angelica, 4 to 7 grams of root of red-rooted salvia, 3 to 6 grams of medlar, 6 to 20 grams of tuber fleeceflower root (prepared), 4 to 8 grams of red raspberry, 4 to 7 grams of south dodder seed, 4 to 7 grams of common macrocarpium fruit, 4 to 7 grams of malaytea scurfpea fruit, 4 to 8 grams of desertliving cistanche, 6.5 to 11 grams of mulberry fruit, 6.5 to 11 grams of black sesame, 6.5 to 11 grams of black soybean, 4 to 8 grams of szechwon tangshen root and 4 to 8 grams of astragalus, wherein cane sugar is used as an auxiliary material. The preparation methodcomprises the following steps of: decocting all Chinese patent medicaments in water to obtain decoction, and concentrating the decoction to form thick paste; pulverizing the stir-fried black sesame, the stir-fried black soybean and the donkey-hide glue; pulverizing the cane sugar powder serving as the auxiliary material; and mixing the black sesame powder, the black soybean powder and the donkey-hide glue powder with the cane sugar powder serving as the auxiliary material uniformly, adding the mixture into the concentrated thick paste, mixing uniformly, pelletizing and drying to obtain a solid preparation for oral administration.

The invention discloses a Chinese patent drug for treating diabetes and a preparation method thereof, relating to the technical field of traditional Chinese medicine. The Chinese patent drug comprises the following effective ingredients in parts by weight: 50-70 parts of grapestone, 50-70 parts of white tea, 50-70 parts of lucid ganoderma, 50-70 parts of ginseng, 50-70 parts of hawthorn, 3-5 parts of the root of red-rooted salvia, 10-15 parts of rhizoma atractylodis, 10-15 parts of vine root, 10-15 parts of folium mori, 20-25 parts of bitter gourd, 10-15 parts of Cyclocarya paliurus, 10-20 parts of garlic, 20-30 parts of pumpkin powder, 10-20 parts of persimmon tree leaf, 10-20 parts of corn stigma, 5-20 parts of pomegranate, 5-15 parts of semen coicis, 10-15 parts of Coptis chinensis, 10-15 parts of lophatherum gracile, 5-10 parts of turmeric and 10-15 parts of eucommia bark. The Chinese patent drug prepared with the preparation method has the efficacy on lowering cholesterol, lowering blood fat, lowering blood pressure, lowering blood sugar, improving internal fat metabolism, enhancing organism immunity functions and the like and can be used for treating diabetes.

The invention relates to a manufacture process of toad venom, which adopts latex of mammalian to soak and treat the solubility component extracted from the toad venom. The invention can improve lasting hemp tongue feeling of a patient's mouth effectively and achieve the degree that patients are willing to accept. The toad venom processed by the process of the invention is applied into Chinese patent drug which comprises the toad venom, thereby further improving the taste of the Chinese patent drug and enhancing compliance and endurance of patients to the invention.

The present invention discloses a semantics-based cross-language patent novelty predetermining analysis method. The method comprises the steps of reading classified information of Wikipedia, extracting keywords, synonyms and related words of an article title, a disambiguation page and a redirection page, and building a cross-language semantic network structure; extracting Chinese keywords from a to-be-examined Chinese patent, reading related words of the Chinese patent from a cross-language knowledge bank, combining and expanding the multiple Chinese keywords and the related words, so as to form multiple groups of Chinese inquire words, translating the Chinese inquire words into corresponding English inquire words for retrieving, so as to obtain multiple similar English files; and extracting English keywords, performing similarity calculation, predetermining the novelty, building a tree map through hierarchical clustering, and outputting the most similar English files. Through adoption of the method, a cross-language comparison policy is made, patent writing and examination efficiency can be improved greatly, patent declaration and approval time is shortened, patent declaration and examination efficiency is improved, and the method has high promotion value.

The invention relates to a medicament for curing tummy bug, wherein the proportion by weight of the materials of the medicament is that toosendan fruit 6-12, jasmine flower 3-7, paleaceous knotweed 15-25, white peony 10-14, saruma henryi oliv 3-7, corydalis 6-12, cuttlebone 6-12, wilford swallowwort 3-7, linaloe 6-12, dandelion 15-25, cyperus tuber 6-12, stink bug 3 -7, lindera root 6-12, evodia rutaecarpa 7-13; frying immature bitter orange 3-7, frying citrus aurtantium 3-7, ageratum peduncle 1-5, magnolia bark 1-5, sandalwood 4-8, reed rhizome 1-5, zanthoxylum 1-3, spikenard 3-7, kaki calyx3-7, pinellia tuber 6-10, tangerine peel 1-3, and green orange peel 1-5. The medicament of the invention has unique curative effect towards the treatment of chronic superficial gastritis. Compared with the present Chinese patent medicament, the invention has good curative effect, convenient dosing, low curing charge and quick execution. Moreover, the invention can relieve the pain within 6-8 minutes after being taken, and can radically cure the tummy bug without toxic and side effects, and thereby the invention is a perfect Chinese patent medicament for curing tummy bug.

The invention provides a method for detecting a Chinese patent drug containing at least two of white paeony root, ginseng, salvia miltiorrhiza, sweet wormwood, liquorice and angelica sinensis, comprising the steps as follows: preparing a sample solution and a comparison product drug solution, adopting acetonitrile and water as mobile phases, and performing high performance liquid chromatography (HPLC) measurement, wherein the detection wavelength is 201-290nm; and detecting whether a corresponding chromatographic peak exists at a position, which has the same reservation time with the chromatograph of a comparison drug, in the chromatography of a sample. Compared with the traditional thin-layer chromatography identification method, the detection method in the invention has the advantages that the mode of processing a sample containing various drugs in a liquid phase chromatograph is changed, the mixed peak in the liquid phase chromatography except the components to be detected in the Chinese patent drug is successfully eliminated, and results are more accurate and stable.

The invention discloses a system and a method for quickly detecting chemical components added in medicine, health-care food and food. The detection system comprises a database of the added chemical components, a primary screening device or a kit, a confirmation instrument and an LC-MS (liquid chromatography-mass spectrography) instrument. The detection method comprises the following steps: establishing a database of the added chemical components, primarily screening the database of the added chemical components by using a quick screening method, further confirming the screening result, and finally arbitrating the screening result by using an LC-MS method. The system and the method realize effective supervision for illegally-added chemical components in Chinese patent medicine, health-care food and food, solve the difficult problem of supervision resource deficiency, comprehensively promote the capability and level of illegal addition detection for the Chinese patent medicament, health-care food and food, provide powerful technical support for legal supervision, form great deterrent for lawbreakers who sell fake medicament, and have quite important significance for ensuring the safety and the validity of diet medicament of people and protecting the fame of Chinese medicaments.

The invention relates to a Chinese patent text similarity calculation method, which is used for calculating text similarity based on the fusion of an SAO structure and a vector space model, and comprises the following steps: extracting an SAO triple from a patent text; calculating the similarity of words in the SAO triple; calculating the similarity between the SAOs; calculating the patent text similarity based on the SAO; and fusing the vector space model method and the SAO structure-based method. According to the Chinese patent text similarity calculation method provided by the invention, the patent text similarity is calculated on the basis of the SAO structure and vector space model fusion method, the advantages of the SAO structure and the vector space model are brought into full play, the defects of the SAO structure and the vector space model are overcome, excellent correct rate, recall rate and F value are obtained, and the requirements of practical application can be well met.

The invention relates to a method for extracting non-taxonomy relations between entities for Chinese patents. The method comprises following steps: S1): initializing basic relation sets of concept pairs; S2): automatically marking candidate relational words by use of a relational word marking algorithm based on domain relation intensity; S3): performing characteristic selection to obtain characteristic vectors; S4): performing classification to the characteristic data obtained in S3) by use of a support vector machine SVM. According to the invention, the extraction of non-taxonomy relations between entities for Chinese patents is defined as extraction of relations between entities which suit a SAO structure; a method of syntactic analysis characteristics and relational word dictionary characteristics in combination with traditional characteristics is brought forward, and a support vector machine is used for relation extraction so that the problem of right relation example structures with semantic errors in SAO structure relation extraction task is solved; the method is prior to traditional relation extraction method and can better satisfy practical application needs.

The invention discloses a medicine for treating gynecological diseases and skin diseases and a preparation method thereof. The medicine is a Chinese patent drug which is prepared by the raw materials of phellodendron, radix sophorae flavescentis, common cnidium fruit, rhizoma atractylodis, honeysuckle flower, cortex dictamni, fructus kochiae and rehmanniae radix according to a certain preparation technique. By adopting the common local Chinese herbal materials as raw materials, the medicine of the invention has low cost; furthermore, the medicine of the invention has the efficacies of clearing away heat, eliminating dampness, dispelling wind, killing parasites, diminishing inflammation and relieving itching and can achieve good curative effect. Moreover, the medicine of the invention has the advantages of easy preparation, low cost and significant curative effect, thus being applicable to the treatment of pruritus vulvae, vaginitis, cervicitis, eczema scroti and verruca acuminate which are caused by various pathogenic bacteria and skin diseases caused by a variety of fungus.

The invention provides a honeysuckle extract and a preparation method for extracting chlorogenci acid. The method has the advantages of good repeatability and good stability; by using the method, the content of an active component can be improved, a large amount of impurities are removed, raw materials are high in yield and low in cost; and the method is suitable for industrial production. The percentage of the main active component chlorogenci acid in the honeysuckle extract is 30%. The preparation process of the honeysuckle extract comprises the following steps: adding water the volume of which is 8-20 times as large as that of taken honeysuckle medicinal material in the taken honeysuckle medicinal to extract for 2-4 times for 0.5-1.5 hours each time; regulating the pH value of the extract to 1-6; and on a large pore absorption resin column, eluting impurities with water firstly, then eluting with 10-70% ethanol, colleting ethanol eluent, recovering the ethanol, concentrating, regulating the pH value of a concentrated liquid to 1-6, adding ethyl acetate for extraction, recovering the ethyl acetate, concentrating and drying. By using the method, the content of the active component in the extract is improved, the curative effect is improved, a large amount of impurities are removed, the problem of large moisture absorption commonly occurring in Chinese patent medicines is solved, and side effects are reduced.

The invention relates to a method for automatic term identification of a Chinese patent literature, which comprises the steps that at a step (1), a word nature rule is automatically generated based on a patent title; at a step (2), a stop word list is generated manually; at a step (3), the generated word nature rule is classified according to number of contained word natures; and at a step (4), candidate terms are sequenced according to a TermRank sequencing algorithm. The method for the automatic term identification of the Chinese patent literature provided by the invention firstly automatically learns the word nature rule constituting the term from the patent title by a statistic method in order to solve the deficiency in manual summarization of term word nature rules. The method sequences the candidate terms by the TermRank sequencing method, takes comprehensive account of linguistic and statistic characteristics in patent literatures, can effectively distinguish terms from non-terms, has high reliability and can satisfy demands of actual applications very well.

The invention discloses a Chinese medical preparation for curing gastrointestinal diseases. The invention is a Chinese patent drug by taking salvia miltiorrhiza root, largehead atractylodesrhizome, mantis egg-case, tuber bletillae, immature bitter orange, liquoric root, rhizoma corydalis, chicken's gizzard-membrane, rhubarb, bergamot, coastal glehnia root, eaglewood, dried ginger, costustoot, fructus piperis longi, cinnamon, and baical skullcap root as raw materials and prepared with traditional preparation technique. The invention has the advantages of reliable treatment effect, simple preparation technique, easy operation, good reproduction quality, good internal quality and stability of the preparation, safety and innocuity, no anaphylactic reaction and other adverse effects, large clinical demand, rich medicine source, low cost, promising market prospect and being suitable to industrial production.

The invention belongs to the technical field of biology, and particularly relates to a marker polypeptide for identifying pilose antler and antler of sika deer or red deer and application thereof. The marker polypeptide provided by the invention specifically comprises: a peptide fragment 1 which is as shown in SEQ ID No. 1: KAPQVSTPTLVELSR; and a peptide fragment 2 which is as shown in SEQ ID No. 2: HHGGEFTVVLQADFQK. The marker polypeptide and the detection method provided by the invention provide reference for searching marker peptide fragments in the related species lacking in the database. The marker polypeptide provided by the invention has excellent specificity and stability for pilose antler and antler of sika deer or red deer, is high in specificity, can be used for identifying pilose antler and antler medicinal materials, decoction pieces thereof and Chinese patent medicines fed by using raw powder, and has a good application prospect.

The invention discloses a benzisoselenazolone-modified pyrrolyl formate-substituted indolone compound and a use thereof. The invention depends on and claims the priority of a Chinese patent application 201110105248.0 submitted on April 26, 2011. Through reference, all contents of the Chinese patent application 201110105248.0 are incorporated into the invention. The benzisoselenazolone-modified pyrrolyl formate-substituted indolone compound is shown in the general formula I. The 2-indolone compound provided by the invention has excellent antitumor activity and can be widely used for preparation of antitumor drugs.

The invention relates to a method for cultivating and producing polygalacic acid with polygala root hair-shaped roots, which uses polygala root hypocotyl and blades as an explantation and converts by activating hair-shaped root agrobacterium, and leads T-DNA of hair-shaped root agrobacterium Ri plasmid to be integrated to polygala root nucleus DNA for expressing and forming hair-shaped roots, and polygala root hair-shaped roots are gained through plural times of subinoculation. The polygala root hair-shaped roots which are gained contain the same components of polygalacic acid (namely, senega-saponin) as that of traditional Chinese medicine polygala root, and the content is not lower than the wild traditional Chinese medicine polygala root. The invention can be used as new medicine resources to provide polygala root products, which solves the practical problems that the demand amount of polygala root is increased year by year, and wild resources are lacked and the quality of cultivated breeds is reduced, which brings practical problems to clinic, Chinese patent drug processes and export.