Preparation method for extracting chlorogenci acid from honeysuckle and application of honeysuckle extract

A technology of honeysuckle extract and chlorogenic acid, applied in the direction of carboxylic acid ester preparation, organic compound preparation, chemical instruments and methods, etc., can solve the problems of difficult quality standard control, inconvenient use, complex components, etc., and achieve the solution of absorption High tide, easy operation, less toxic and side effects
CN102134192AInactive Publication Date: 2011-07-27重庆市集银中药材有限责任公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
重庆市集银中药材有限责任公司
Publication Date
2011-07-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a honeysuckle extract and a preparation method for extracting chlorogenci acid. The method has the advantages of good repeatability and good stability; by using the method, the content of an active component can be improved, a large amount of impurities are removed, raw materials are high in yield and low in cost; and the method is suitable for industrial production. The percentage of the main active component chlorogenci acid in the honeysuckle extract is 30%. The preparation process of the honeysuckle extract comprises the following steps: adding water the volume of which is 8-20 times as large as that of taken honeysuckle medicinal material in the taken honeysuckle medicinal to extract for 2-4 times for 0.5-1.5 hours each time; regulating the pH value of the extract to 1-6; and on a large pore absorption resin column, eluting impurities with water firstly, then eluting with 10-70% ethanol, colleting ethanol eluent, recovering the ethanol, concentrating, regulating the pH value of a concentrated liquid to 1-6, adding ethyl acetate for extraction, recovering the ethyl acetate, concentrating and drying. By using the method, the content of the active component in the extract is improved, the curative effect is improved, a large amount of impurities are removed, the problem of large moisture absorption commonly occurring in Chinese patent medicines is solved, and side effects are reduced.
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Description

technical field

[0001] The invention relates to a honeysuckle extract, a method for extracting chlorogenic acid from the traditional Chinese medicine honeysuckle, and the application of the extract in dosage forms such as tablets, granules, and capsules, and in preparing heat-clearing, detoxifying, and anti-infective drugs. Background technique

[0002] This product is the dry flower bud or the first flower of Lonicera japonica Thunb. Harvest before the flowers bloom in early summer and dry them; or smoke them with sulfur and then dry them. Mostly produced in Shandong and Henan, mostly cultivated. The main effect is to clear away heat and detoxify, cool and dispel wind-heat. For carbuncle swollen furuncle, sore throat, erysipelas, pyretic toxin bloody dysentery, wind-heat cold, febrile disease heating.

[0003] In recent years, scholars at home and abroad have carried out comprehensive analysis and research using modern theoretical knowledge, and done a lot of pharmacolog...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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