The invention provides a fully-automatic screw locking machine for a radiator. The fully-automatic screw locking machine comprises a rack, as well as a radiating fin loading mechanism, a triode loading mechanism, a screw loading mechanism, a screw locking mechanism, a screw detection mechanism for detecting installation missing of screws, a forming mechanism, a forming and foot-cutting mechanism, an unloading mechanism and a multi-station rotary disc mechanism which are installed on the rack respectively, wherein the radiating fin loading mechanism, the triode loading mechanism, the screw locking mechanism, the screw detection mechanism, the forming and foot-cutting mechanism and the unloading mechanism are sequentially distributed at the periphery of the rotary disc of the multi-station rotary disc mechanism along the rotation direction of the rotary disc, and are orderly and respectively matched with corresponding station clamps on the rotary disc; and the screw loading mechanism is arranged at one side of the screw locking mechanism, and matched with the screw locking mechanism. The fully-automatic locking screw machine provided by the invention can be used for automatically sequencing, assembling, screw locking, forming and discharging after radiating fins are placed in a radiating fin vibration disc in batches, whole triodes are placed in a triode feeding slide way, and screws are placed in a screw vibration disc in batches.