Pharmaceutical formulations with the raw material containing panax, ophiopogon root and schisandra fruit, processes for their preparation, the raw material and the quality control method for the prepa

Abstract

The present invention relates to a medicine preparation with raw material comprising gen-seng, RADIX OPHIOPOGONIS and schizan drin and relates to the methods of preparing and quality control of the invention as well as relates to the quality control method of the raw material comprising gen-seng, radix ophiopogonis and schizan drin. The present invention comprises saponins content of gen-seng, amylase content of gen-seng, saponins content of radix ophiopogonis and neolignan content of schizan drin. Each unit dosage of preparation comprises Rg1 and Re for 0.08 mg-12 mg, polysaccharide of gen-seng for 1mg-460mg, general saponins for 5 mg-800 mg and Schisandrin for 0.036mg-6mg. a medicine functioning as cooperation can be or can not be added in the present invention which can be any acceptable medicine preparation type comprising oral taking solid preparation, oral taking semi-solid preparation, oral taking liquid preparation and injection. The present invention also provides the quality control method of gen-seng, RADIX OPHIOPOGONIS and schizan drin as well as the quality control method of the present invention.

Description

technical field [0001] The invention belongs to the field of medicines, and specifically relates to a pharmaceutical preparation containing ginseng, radices japonicus and schisandra in its raw materials, a preparation method, a quality control method, and a quality control method for the raw materials of ginseng, radix radix and schisandra. Background technique [0002] The ancient prescription "Shengmaisan" is composed of ginseng, Ophiopogon japonicus, and Schisandra chinensis. It has the effects of nourishing qi and nourishing yin, and restoring the pulse. It is mainly used for palpitations, shortness of breath, cold limbs, sweating, and pulse. Desperate. [0003] Modern medical research has proved that the drug has the effect of dilating blood vessels and increasing coronary blood flow, and can be used to treat cardiovascular diseases such as myocardial infarction, cardiogenic shock, and septic shock. [0004] Ginseng contains saponins, polysaccharides, β-elemene, panaxy...

AI Technical Summary

Problems solved by technology

[0009] When the traditional Chinese medicine compound prescription is used for oral administration, if all kinds of ingredients in the prescription that can produce pharmacological effects are fully retained in the finished preparation, the original efficacy of the prescription can be better preserved, but there are often excessive dosages. big problem

[0010] When the Chinese medicine compound is made into injections, if we try our best to keep all the ingredients that can produce pharmacological effects in the prescription, the prepared injections will either retain too many impurities, and bring in various risks of uncontrollable impurities during injection administration. It is difficult to find a safe and effective quality control method for the prepared injection, and it is difficult to guarantee the safety and stability; or the production process of separating and purifying each monomer component is extremely complicated, the cost is extremely high, and it has no practical significance

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