113 results about "Crude drug" patented technology

The preparation method comprises the following steps: extracting hedera helix leaves with 75%-85% ethanol, concentrating, adjusting the pH value to 9.5-11, standing, filtering to obtain a crude extract, passing the crude extract through a chromatographic column, and eluting with 60%-80% ethanol to obtain the hedera helix extract; the chromatographic column is an HPD100 macroporous resin column, a polyamide column or a C18 column. The invention also provides pharmaceutical application of the hedera helix extract. By optimizing the preparation process, anti-inflammatory components in the hedera helix raw material are enriched, the yield of the obtained extract is increased, the saponin content is reduced, but the anti-inflammatory effect of the obtained extract is better, and an unexpected technical effect is achieved. According to the invention, the technical prejudice of increasing the content of saponin in the prior art is overcome, the hedera helix extract with better anti-inflammatory effect and higher yield is obtained on the basis of simplifying the elution procedure, the anti-inflammatory activity of the extract is increased, the anti-inflammatory effect is better under the condition of the same weight of crude drug, the dosage is reduced, and the cost is reduced. The economic benefit and the utilization rate of the raw medicines are improved.

The present application belongs to the technical field of biological fermentation, and discloses a natural plant fermentation liquor, which is prepared from acanthopanax, angelica sinensis, rosa davurica, phellinus baumii, tea leaves, water, mixed enzymes and mixed bacterial agents; wherein the mixed enzymes include cellulase, pectinase and tannase, and the mixed bacterial agents include lactobacillus plantarum, schizosaccharomyces and lactobacillus acidophilus.The natural plant fermentation liquor has high safety, good clarity after adjusting the concentration of crude drugs, and can be added into a cosmetic matrix.The preparation method is simple, and the effective active ingredients of the natural plants and tea leaves are extracted by the synergistic effect of bacteria and enzymes to the maximum extent.In addition, the present application also discloses the application of the natural plant fermentation liquor in preparing cosmetics for treating oily sensitive skin.

The invention belongs to the technical field of biological fermentation, and discloses a natural plant fermentation liquid which is prepared from the following raw materials: radix acanthopanacis senticosi, radix angelicae sinensis, fructus rosae laevigatae, phellinus linteus, tea leaves, water, mixed enzyme and a mixed bacterial agent. Wherein the mixed enzyme comprises cellulase, pectinase and tannase, and the mixed microbial agent comprises plant lactobacillus, bifida and lactobacillus acidophilus. The natural plant fermentation liquor is high in safety and good in clarity after the concentration of crude drugs is adjusted, and can be added into cosmetic matrixes. The preparation method is simple, and effective active ingredients of natural plants and tea leaves are extracted to the maximum extent through the synergistic effect of bacteria and enzymes. In addition, the invention also discloses application of the natural plant fermentation liquor in preparation of cosmetics for treating oily sensitive skin.

The invention relates to application of an Artemisia rupestris extract in preparation of medicines for preventing and treating lung diseases. According to the application of the artemisia rupestris extract in preparation of the medicine for preventing and treating the lung diseases, the artemisia rupestris extract is prepared by taking artemisia rupestris as a raw material, and the crude drug concentration is 20-110 mg / mL. The artemisia rupestris extract contains chemical components such as sesquiterpenoids, flavonoids, organic acids and phenylpropanoids. The medicine is a veterinary medicine. The lung diseases comprise allergic pneumonia, pulmonary fibrosis or diseases caused by injury of other lung tissues. The dosage form of the medicine for preventing and treating the lung diseases is a pharmaceutically acceptable dosage form. The pharmaceutically acceptable dosage form is oral liquid, powder, tablets, granules, capsules, pills, syrup, suspension or emulsion. The application defines the prevention and treatment effect of the Artemisia rupestris extract on lung diseases. During application, the artemisia rupestris extract is small in dosage and high in curative effect, and the weight of livestock and poultry can be greatly reduced due to the fact that lung tissue is damaged.

The application discloses a preparation method of fenbendazole impurity C, wherein the fenbendazole impurity C is impurity C in the European Pharmacopoeia (EP), and the compound has a molecular formula of C 27 H 23 N5O2S2, the application takes 2-nitro-5-phenylmercaptoaniline as raw material, realizes the preparation of the fenbendazole impurity C through a four-step reaction in the following route, the preparation method of the impurity compound is easy to obtain raw materials, simple to operate, reasonable in process design, relatively mild in reaction condition, high in yield, and can realize industrial production, the prepared fenbendazole impurity C can be used as a control sample for qualitative and quantitative research of impurity C in fenbendazole quality research, the content of the fenbendazole impurity C is controlled, so that the quality of the crude drug is ensured.

The present invention provides an agent for maintaining or improving brain function, which comprises a crude drug selected from the group consisting of a Ziziphi Spinosae Semen and a stem portion of Acorus tatarinowii Hizoma, as a novel means for maintaining or improving cognitive function. The semen ziziphi spinosae is selected from crushed materials and extraction residues of the crushed materials, and the rhizoma acori graminei stem part is selected from crushed materials, extracts of the crushed materials and extraction residues of the crushed materials.

The invention relates to a formula and a preparation method of compound desert cistanche granules, the compound desert cistanche granules are prepared by adding flavor on the basis of Qingzheng dialectical record yang-warming soup, the raw materials comprise desert cistanche, bighead atractylodes rhizome, monkshood, Chinese angelica, cynomorium songaricum, fried semen raphani and perillaseed, and the total weight of a single bag is 7g. The production process comprises the key steps of pretreatment of medicinal materials, independent first decoction of radix aconiti carmichaeli for detoxification, extraction of semen raphani and perillaseed volatile oil, inclusion of beta-cyclodextrin, combined decoction and concentration of all the medicinal materials, dry granulation and the like, and the technical effects that granules are instantly dissolved within 45 + / -5 seconds and the transfer rate of crude drugs is 91.2% are achieved by optimizing the proportion of auxiliary materials and process parameters. The quality of the finished product meets the requirements of Chinese Pharmacopoeia, the content of aconitine is less than or equal to 0.02%, the total number of microbial limit aerobic bacteria is less than or equal to 100 CFU / g, the problems that a traditional compound cistanche deserticola preparation is slow in dissolution speed, unstable in toxicity control and non-standard in production process are solved, and the method is suitable for large-scale industrial production.

The present invention relates to the field of pharmaceutical preparations, and in particular, to a sevelamer carbonate dry suspension and a preparation method thereof. In the sevelamer carbonate dry suspension, the dosage of the suspending agent is 0.13 - 0.33% of the total mass, the dosage of the flocculant is 0.05 - 0.39% of the total mass, the dosage of lactulose is 72.53 - 86.90% of the total mass, the dosage of the flavoring agent is 0.34 - 0.72% of the total mass, and the dosage of the sevelamer carbonate crude drug is 12.51 - 26.20% of the total mass. This sevelamer carbonate dry suspension not only has excellent dispersibility, but also can improve its gastrointestinal side effects.

The utility model discloses a medicinal material processing impurity removal screening mechanism, and particularly relates to the technical field of medicinal material processing.The medicinal material processing impurity removal screening mechanism comprises a rectangular box, supporting plates are fixedly connected to the left and right portions of the lower end of the rectangular box, a box door is rotatably connected to the left portion of the rear end of the rectangular box, and a guide plate assembly is arranged on the lower side of the inner surface of the rectangular box; a screening assembly is arranged in the middle of the inner surface of the rectangular box, and a dust removal assembly is arranged on the upper portion of the front end of the rectangular box. According to the impurity removing and screening mechanism for medicinal material processing, the screening assembly is arranged, so that all impurities such as soil or gravel in traditional Chinese medicinal materials can be screened out, and therefore the purity of the medicinal materials is improved; the guide plate assembly is arranged, so that the screened impurities can be collected in a centralized manner; and a dust removal assembly is arranged, dust raised in the screening process of the traditional Chinese medicinal materials in the rectangular box can be absorbed, in this way, impurities in the traditional Chinese medicinal materials can be further removed, and therefore the quality of the traditional Chinese medicinal materials is further improved.

The present invention provides a thin-layer identification chromatographic method for Celosiae Semen and stir-fried Celosiae Semen formula granules, including: spotting the test solution on a silica gel G thin-layer plate, developing under thin-layer chromatographic conditions, and inspecting; the thin-layer chromatographic conditions: using toluene-ethyl acetate-methanol as the developing agent. By comparing the thin-layer chromatogram of the stir-fried Celosiae Semen formula granules with that of the Celosiae Semen control medicinal material and the Celosiae Semen granules, the same position with a retention factor value at 0.55-0.67 should not show fluorescent spots, which is used as the identification point 1 of the stir-fried Celosiae Semen granules; by comparing the thin-layer chromatogram of the stir-fried Celosiae Semen formula granules with that of the Celosiae Semen control medicinal material and the Celosiae Semen granules, the same position with a retention factor value at 0.43-0.52 has one more fluorescent spot, which is used as the identification point 2 of the stir-fried Celosiae Semen granules. This method can quickly and effectively identify the stir-fried Celosiae Semen formula granules that have lost the form of the cut crude drug, with simple operation, high precision, high sensitivity, good stability, and has good application prospects.

To provide a pharmaceutical composition exhibiting superior effects in improving oral hygiene, in particular tongue coating and / or halitosis.SOLUTION: Incorporating menthol into a pharmaceutical composition containing Shokyo-shashin-to extract delivers a superior oral hygiene effect.SELECTED DRAWING: None

The utility model discloses artificial sorting operation platform of grass department crude drug, including sorting table and support leg, the sorting table top one side position welds has the baffle. The utility model discloses a sorting groove, storage groove, baffle has been used, and when sorting the raw material, personnel can add the raw material through the sealing cover at the baffle at the top of sorting groove, then can drive the raw material from the inside to the outside exposure through the movement of the push board of corresponding position, and the sorting operation is convenient, and the raw material that sorts out can be placed to the storage groove, and through the push board in it, the raw material is pushed from the outside to the inside and realizes the storage operation, since sorting and storage operation all are protected through the baffle, and each time is a small amount of exposure, therefore can effectively avoid the dispersion and the drift of raw material due to external vibration or the blowing of air current, effectively avoid the problem that grass department crude material is relatively light and soft, has the advantage that sorting protection.

The utility model discloses a raw material medicine fine separation and purification device which comprises a base, the upper surface of the base is rotationally connected with a rotating table, a first motor is installed in the rotating table, the output end of the first motor is fixedly connected with a first gear, the outer surface of the first gear is connected with a second gear in a meshed mode, and the upper surface of the second gear is fixedly connected with a stirring rod. A purification device main body is fixedly connected to the upper surface of the rotating table, a split pipe is fixedly connected to the upper surface of the purification device main body, and a gear I is rotated through a motor I, so that a meshed gear II rotates in a stirring rod in the purification device main body; a motor II rotates a gear III, so that a meshed gear ring and a rotating table on the inner wall of the gear ring rotate, the rotating table rotates to enable the purification device main body to do circular motion, and meanwhile, the rotating directions of a stirring rod and the rotating table are opposite, so that the liquid medicine stirring effect is further improved, the liquid is more fully mixed, and the phenomena of chromatography and non-uniform mixing can be effectively reduced.

The invention belongs to innovative plasters, and relates to a transdermal drug delivery technology, in particular to a traditional Chinese medicine gel plaster for palpitation, heart health regulation and cardiovascular circulation improvement and a preparation method of the traditional Chinese medicine gel plaster. Through a transdermal drug delivery mode, the medicine has the obvious advantages of being good in viscosity, high in permeability, rapid in absorption, high in safety and large in drug carrying amount, and meanwhile the problems that no external drug treatment vacancy exists in the heart field, and heart abnormality cannot be rapidly relieved under the condition that the medicine is difficult to take and eat in the heart field are solved.

The present invention provides a test method for toxicity of raw dinotefuran drug on early life stage of fish. The method includes: preparing a standard diluent, preparing test drug liquids, selecting a test organism, toxicant exposure of the embryos, toxicant exposure of larvae, monitoring and controlling test conditions, observation in the test, and statistically analyzing data and drawing results.

The present invention provides an agent for maintaining or improving brain function, which contains a crude drug selected from the group consisting of leaves, fruits, and seeds of Laphania tetrandra.

The invention provides a preparation method of impurity reference substances of three cis-isomers of vitamin A palmitate, and the three cis-isomers are respectively a 13-cis-isomer, a 9, 13-bis-cis-isomer and a 9-cis-isomer. The preparation method comprises the following steps: dissolving vitamin A palmitate with n-hexane, carrying out oxidative damage, carrying out isocratic elution by adopting a preparative liquid chromatograph to separate out solutions of three cis-isomer impurities, and concentrating in a dark place to obtain the reference substances of the three cis-isomer impurities of the vitamin A palmitate. The method disclosed by the invention is simple, can be used for simultaneously preparing three cis-isomers of vitamin A palmitate in a short time, and can be used for researching vitamin A palmitate crude drugs and related substances of related products, so that the quality control detection of the cis-isomers of vitamin A palmitate is realized, and the application prospect is wide. The quality standards of the vitamin A palmitate and the preparation thereof are further improved.

The invention relates to application of germplasm of botryosphaeria formosa to preparation of health-care products for improving antioxidation, and belongs to the technical field of functional evaluation of health-care foods, the germplasm of botryosphaeria formosa promotes expression of superoxide dismutase (SOD), glutathione (GSH) and glutathione peroxidase (GSH-PX) by inhibiting accumulation of peroxide malonaldehyde (MDA) in heart, liver and serum, so that the anti-oxidation effect of the botryosphaeria formosa is improved, and the anti-oxidation effect of the botryosphaeria formosa is improved. The anti-oxidation regulation function is realized. The boil bean germplasm is extracted for 30 minutes by adopting boiling water, so that the use of an organic solvent is avoided to retain natural active ingredients, and the boil bean milk containing 1g / mL of crude drug is obtained and is used for preparing antioxidant health-care products. The health-care product is suitable for prevention or adjuvant treatment of diseases caused by oxidative stress, such as cardiovascular diseases, liver injury or aging related diseases. Experiments prove that the anti-oxidation effect of the germplasm of the botryosphaeria formosa is evaluated, the germplasm of the botryosphaeria formosa has a reliable anti-oxidation regulation effect, the MDA level in the heart, the liver and serum can be remarkably reduced, and the expression of SOD, GSH and GSH-PX is promoted.

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine external preparation for dispelling wind and arresting itching and application thereof. The traditional Chinese medicine external preparation is prepared from the following raw materials: 10-30 parts of fried fructus xanthii, 10-30 parts of fructus kochiae, 10-30 parts of rhizoma chuanxiong, 10-30 parts of flos carthami and 5-15 parts of solanum lyratum thunb. The raw materials are subjected to process extraction and refining to obtain the traditional Chinese medicine external preparation. A plurality of processes are researched, and research results show that the itching relieving and detumescence effects of the transdermal drug delivery preparation are obviously superior to those of original oral granules, and the effect is better than that of dermatitis treatment cream sold in the market. According to the traditional Chinese medicine external preparation disclosed by the invention, the anti-inflammatory, detumescence and itching-relieving drug effects are improved, oral administration is changed into external administration, the administration is more direct, the safety is higher, the drug effects are better, the crude drug amount is smaller, and the cost is lower.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a medicinal and edible composition with effects of dispelling effects of alcohol and protecting liver as well as a preparation method and application of the medicinal and edible composition. The composition is prepared from the following raw materials in parts by weight: 45 to 50 parts of radix puerariae, 28 to 33 parts of semen hoveniae and 10 to 15 parts of flos lonicerae. The preparation method comprises the following steps: performing water extraction, concentration and drying on raw materials to obtain an extract A; or centrifuging, dialyzing and filtering the concentrated solution, and drying to obtain an extract B; according to the invention, three medicinal and edible substances are compatible according to an optimal ratio (50 of radix puerariae, 30 of hovenia dulcis thunb and 12 of honeysuckle), the blood ethanol concentration is synchronously reduced, the liver injury is repaired, and the gastric inflammation is inhibited, the equivalent efficacy of the extract A (1.12 g / kg) is realized by the extract B at the dosage of 0.12 g / kg, and the burden of the liver and the kidney is reduced. The traditional Chinese medicine composition is suitable for development of anti-alcoholism medicines, liver-protecting functional foods and beverages, and the equivalent weight of crude drugs per day is 5-15g.

The present invention belongs to the technical field of traditional Chinese veterinary medicine, and relates to a traditional Chinese veterinary medicine formula, a preparation method and an application thereof. The traditional Chinese veterinary medicine formula is composed of the following raw materials: geranium, Viola yedoensis, Atractylodes macrocephala, Vitex rotundifolia and Licorice, and the weight ratio of each raw material is (2-4): (2-4): (1-3): (1-3): 1. The preparation method of the formula comprises the following steps: weighing geranium, Viola yedoensis, Atractylodes macrocephala, Vitex rotundifolia and Licorice in weight proportion and mixing them, refluxing extraction, collecting the extract, combining the extracts after repeated multiple times and vacuum filtering, concentrating the filtrate to 1g crude drug / mL, freeze drying, grinding into fine powder and sieving to obtain. The traditional Chinese veterinary medicine formula provided by the present invention is used for the prevention and treatment of intestinal diseases of livestock and poultry in animal husbandry, especially bacterial intestinal diseases caused by bacterial infection, and has antibacterial, anti-inflammatory and immune-enhancing effects.

The present application relates to a thin-layer detection method for Semen Lablab Album traditional Chinese medicine formula granules and its application in the identification of counterfeits. The thin-layer detection method for Semen Lablab Album traditional Chinese medicine formula granules comprises the following steps: extracting Semen Lablab Album traditional Chinese medicine formula granules with an aqueous methanol solution having a volume concentration of 65% to 75%, evaporating the obtained extract to dryness, dissolving the solid obtained by evaporation in water, extracting with ethyl acetate, evaporating the obtained ethyl acetate phase to dryness, dissolving the solid obtained by evaporation in methanol to prepare a test solution; preparing a solution of the control crude drug; preparing a reference substance solution by taking chikusetsusaponin IVa reference substance; spotting the test solution, the solution of the control crude drug and the reference substance solution on the same thin-layer plate, developing with a mixed solution of ethyl acetate, n-butanol, glacial acetic acid and water as the developing agent, air-drying, coloring with a coloring agent, and inspecting. This thin-layer detection method is simple, efficient and highly specific in operation.

The present application relates to the technical field of pesticides, in particular to a kind of mesopotamia · isopropylone suspending agent and its preparation method and application, by weight percentage, including: mesopotamia crude drug 5~10%, isopropylone crude drug 30~50%, wetting dispersant 10%~15%, anti-settling thickener 0.3%~1.5%, antifreeze 3~5%, antifoaming agent 0.01~0.5%, fungicide 0.01~0.2%, deionized water makes up the rest amount, while ensuring the sanding efficiency of product, thermal storage stability, cold storage stability, wetting spreading property, better satisfy the actual application demand.

The present invention discloses a method for identifying a thin layer of maca powder, which includes separately weighing 100 mg to 200 mg of the control crude drug of maca root and the maca powder sample, adding an ethanol solution respectively, refluxing in a water bath, vortexing to completely precipitate the solution, and filtering to obtain the corresponding reference solution and test solution. The reference solution and the test solution are respectively spotted on a silica gel thin layer plate and developed in a developing agent which is a mixed solution of chloroform, acetic acid, methanol and water; then the chromatogram formed is inspected under ultraviolet light at 366 nm and sunlight. If the test chromatogram shows spots of the same color at the corresponding positions as the chromatogram of the control crude drug, it contains maca powder. The identification method of the present invention is simple to operate, targeted, the spots are clearly visible, the Rf value is moderate, and it has good durability; it can quickly identify maca powder without complex treatment methods, reagents, instruments or equipment, providing a convenient and practical way for the qualitative identification of maca powder.

The preparation method comprises the following steps: by taking an ixazomib citrate crude product as a starting material, dissolving the ixazomib citrate crude product in tetrahydrofuran and drying by distillation under reduced pressure to obtain an amorphous crude product, and preparing an ixazomib citrate crude drug with a crystal form 2 by using a crystallization solvent in a specific gradient crystallization mode. The method is easy and convenient to operate, the yield reaches 90% or above, solvent residues meet the quality requirement, and the preparation method is suitable for industrial production and further prepares the ixazomib citrate crude product into the ixazomib citrate raw material medicine with the crystal form 2 of which the quality meets the medicinal requirement.

To provide a pharmaceutical for increasing the force of urine flow.SOLUTION: A herbal medicine mixture A containing Poria sclerotium and Plantago seeds, a herbal medicine mixture B containing Poria sclerotium, cinnamon bark and aconite root, and / or their extracts are suitable as an active ingredient of an agent for increasing the force of urine flow.SELECTED DRAWING: None

The invention belongs to the technical field of medicines, and particularly relates to a medicine for treating depression, a traditional Chinese medicine acupoint patch and a preparation method thereof. The medicine is suitable for an acupoint sticking agent and comprises a traditional Chinese medicine composition and a traditional Chinese medicine composition extract, wherein the traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 20 parts of radix bupleuri, 10 to 20 parts of rhizoma cyperi, 10 to 20 parts of radix linderae, 10 to 20 parts of saffron crocus, 5 to 10 parts of flos albiziae, 5 to 10 parts of rhizoma coptidis and 5 to 10 parts of poria cocos. The traditional Chinese medicine composition is completely prepared from Chinese herbal medicines and has no toxic or side effect caused by long-term application of western medicines; the equal amount of crude drugs and traditional Chinese medicine extracts are adopted, the extracts are concentrated into high-activity components, on the basis that the curative effect is improved, the synergistic effect of the crude drugs is better reserved, and meanwhile the patch size problem caused by the too large dosage of the crude drugs is solved; the acupoint patch is applied through skin, the meridian acupoint effect is more remarkable, compared with oral traditional Chinese medicine, the side effect is lower, and the compliance of a user is higher.

The invention discloses a Chinese medicine formula for treating mechanical damage of long-snout catfish, belonging to the field of biological technology of aquaculture. The present invention relates to a medicine for treating mechanical damage of fish, which is composed of three kinds of Chinese medicines: cloves, fennel and rosemary. The crude drug mass ratio is cloves: fennel: rosemary = 2:5:5. After 12g of mixed crude drugs are crushed, 1200ml of water is added and directly decocted or 2.4g of Chinese medicine extracts are mixed and 800ml of water is added and decocted. Finally, the volume is adjusted to 600ml to obtain a "three-fragrant agent". Before use, the injured fish is soaked in 0.5-1% salt water for 15-20 minutes, and then the injured fish is treated for 7-10 days according to the ratio of 0.5-1.0% of the "three-fragrant agent" concentration. The Chinese medicine formula has low toxicity, avoids a series of negative effects caused by conventional treatment using antibiotics, and has good therapeutic effects for treating long-snout catfish and other catfish including scaleless fish such as yellow catfish and yellow catfish.

The invention discloses a rhizoma polygonati extract and application thereof in preparation of a medicine for treating diabetes mellitus. The rhizoma polygonati extract is an aqueous extract of cooked rhizoma polygonati or an n-butyl alcohol extract of the aqueous extract of the cooked rhizoma polygonati, and the concentration of the aqueous extract of the cooked rhizoma polygonati or the n-butyl alcohol extract of the aqueous extract of the cooked rhizoma polygonati is 0.48 g / ml based on the crude drug amount of the cooked rhizoma polygonati. The cooked polygonatum kingianum n-butyl alcohol extract has a good effect of inhibiting the activity of alpha-glucosidase and has a better effect of inhibiting the activity of alpha-glucosidase compared with a polygonatum kingianum water extract, an ethyl acetate extract and a residual water extract, and a new scheme is provided for treating or preventing diabetes mellitus.

The invention belongs to the technical field of traditional Chinese medicine preparations, and provides a lipid-lowering prescription and application thereof, compound lipid-lowering granules and a preparation method and application thereof. The lipid-lowering prescription comprises nine medicinal materials, namely polygonum multiflorum, ginseng, astragalus membranaceus, hawthorn, rhizoma alismatis, eucommia ulmoides, ligusticum wallichii, semen cassiae and oriental wormwood. The lipid-lowering prescription disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, excreting dampness and promoting diuresis, clearing liver and tonifying kidney, and relaxing bowel, and has the potential to be clinically used for treating hyperlipemia and preventing atherosclerotic plaque. According to the invention, the preparation method is optimized, so that about 8g of the compound lipid-lowering granules are orally taken three times a day and 1-2 bags of the granules are orally taken each time on the premise that the daily dose of crude drugs is not changed. And the dosage is greatly reduced. In addition, the compound lipid-lowering granules are beneficial to long-term administration by patients, and are convenient to carry and store. Researches in the aspects of pharmaceutics, pharmacodynamics, toxicology, quality control, stability and the like prove that the compound lipid-lowering granules prepared by the preparation method disclosed by the invention are stable in quality, safe and effective.