10 results about "Toxicant" patented technology

1. Name of the product in this design: Rapid Detection Kit for Toxic Substances. 2. Purpose of this design: This design is used for the rapid detection of toxic substances. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention discloses a method for detecting the toxicity threshold of a substance based on a rat drinking experiment. The method of this invention includes the following steps: First, a drinking preference experiment is conducted, and then the toxicity threshold is determined: the amount of substance water and pure water consumed in the drinking preference is compared to determine the time when the rat begins to significantly avoid substance water, the mass of the toxic substance in the rat's body at that time is calculated, and the toxicity threshold of the rat is calculated; (3) dose conversion from rat to human: based on the interspecies dose conversion of body surface area, the toxicity threshold of the rat is first converted into the equivalent dose for humans to obtain the acute exposure dose, and then the acute exposure dose is converted into the chronic exposure dose for humans to obtain the substance toxicity threshold. This invention can accurately determine the toxicity threshold: it achieves toxicity assessment of low-dose exposure through spontaneous recognition behavior; it is easy to operate; and it is applicable to the toxicity assessment and non-destructive threshold determination of various substances such as environmental pollutants, chemical substances, and drugs.

This invention belongs to the field of biomedicine, and specifically relates to the application of FeTMPyP in the preparation of drugs to alleviate ovarian toxicity. This application addresses the issue that combined exposure to MC-LR and NaNO₂ significantly induces nitrification stress in mouse ovaries, leading to follicular barrier disruption and ovarian reproductive endocrine dysfunction. FeTMPyP was selected as an intervention agent, which effectively alleviated nitrification stress induced by combined exposure to MC-LR and NaNO₂ in mouse ovaries, and improved sex hormone disorders, estrous cycle irregularities, and follicular atresia caused by the combined exposure to these two toxins. Simultaneously, it restored the fertility of mice, indicating that FeTMPyP intervention can alleviate ovarian toxicity induced by combined exposure to MC-LR and NaNO₂ in mice. This invention can be used to prepare drugs to prevent and treat diseases related to ovarian toxicity caused by environmental toxin exposure in mice, providing a new approach for the early identification and targeted intervention of ovarian-related diseases.

The invention relates to a water treatment system suitable for utilization in mobile platform technologies so as to remove TNT and potentially other energetic materials, toxicants and particulate matter from water and a process of utilizing said system.

Provide improved means for transdermally delivering a pesticidal or other toxic agent from a composition containing the toxic agent to a target animal, particularly into its bloodstream. **Solution**: A composition for killing animals, such as rodents, comprising (i) one or more toxic agents toxic to the animal, such as cholecalciferol or 25-hydroxy cholecalciferol (vitamin D3), as a toxic component, and (ii) a carrier system for the toxic component, wherein the carrier system (ii) comprises (a) at least one solvent or dispersion medium for the toxic component, such as an alcohol like ethanol, and (b) at least one skin disrupting component, such as dimethyl sulfoxide (DMSO). The composition enhances the skin penetration of the toxicant into or through the skin of the animal where the composition is sprayed or delivered, for example, in a trap or other device. ​

This invention discloses a device and method for decontaminating chemical toxins using a self-driven plasma synergistic MOF material. The device comprises a triboelectric nanogenerator power supply system and a chemical toxin decontamination system. The triboelectric nanogenerator power supply system serves as the plasma excitation power source, effectively solving the shortcomings of traditional plasma excitation power sources, such as high energy consumption and lack of portability. The plasma electrode is a plate electrode, and MOF material UiO-66-NH2 is grown on its surface using a hydrothermal method, effectively overcoming the problems of inconvenient collection and environmental pollution after MOF material use. MOFs can efficiently adsorb chemical toxins, but the degradation time is relatively long. Plasma can rapidly degrade chemical toxins that have entered the pores. Simultaneously, the highly porous and ordered crystal structure of the MOF material effectively enhances the plasma discharge electric field. The synergistic effect of these two factors can effectively improve the decontamination efficiency of chemical toxins, playing an important role in rapid on-site disposal and emergency rescue applications.

The present disclosure relates to a plate for evaluating toxicants using fish embryos, a method of screening developmental neurotoxicants using the same, and an apparatus and a kit for evaluating developmental neurotoxicants including the plate. The plate and the screening method of the present disclosure provide a novel test method utilizing characteristics of the swim bladder formation process in fish embryos. This method offers an alternative to animal testing and enables effective toxicity evaluation with a small amount of sample.

The present application belongs to the field of animal models, and particularly relates to a construction method and application of an environmental stress source heart failure animal model. The method is as follows: 4-6 week old C57BL / 6 mice are continuously given a mixed heavy metal solution containing lead, mercury and cadmium in the form of free drinking water every day, and when the left ventricular ejection fraction is less than 50%, an environmental stress source heart failure mouse model is obtained. From the perspective of simulating the combined exposure of various heavy metals in the real environment, the present application constructs an animal model highly consistent with the characteristics of clinical heart failure. The modeling method of the present application is simple, and the stability of indexes such as ejection fraction, fractional shortening and BNP in the model is good, the repeatability is strong, the method is reliable, the modeling rate is high, and the model constructed can be used in the fields of exploring the mechanism and molecular target of heart failure, screening drugs for treating heart failure or environmental toxicant evaluation.