772 results about "Toxicant" patented technology

The present invention is directed to the use of immunomodulatory compounds, particularly members of the class of compounds known as IMiDs™, and more specifically the compounds 4-(Amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione and 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione, to induce the expression of fetal hemoglobin genes, genes essential for erythropoiesis, and genes encoding alpha hemoglobin stabilizing protein, within a population of CD34+ cells. These compounds are used to treat hemoglobinopathies such as sickle cell anemia or β-thalassemia, or anemias caused by disease, surgery, accident, or the introduction or ingestion of toxins, poisons or drugs.

The subject invention pertains to materials and methods useful for monitoring and management of certain pests well as others biotic and abiotic factors. The invention is particularly well suited for the control of social insect pests, and particularly, termites. The invention concerns methods and apparatuses for monitoring pest activity and presenting a toxicant. The invention is useful as part of an Integrated Pest Management Program and can significantly enhance the efficacy, efficiency and convenience of the management program.

Automatic pesticide, insecticide, repellant, poison, air freshener, disinfectant or other spray-type delivery systems are proposed for automating the delivery of these items to areas, for controlling pests easier, for improving environmental conditions, and for making it easier to freshen the air and to disinfect areas. The device includes a logic circuit and mechanisms containing a circuit that will enable a user to program the device to discharge a spray of its poison, disinfecting or air freshening spray(s) at a pre-selected time interval or day / time interval chosen in the unit's memory. An electromechanical valve opens to let contents escape when the spraying mechanism of the system is activated. The valve connects to a pressurized spray cylinder and it releases a controlled burst of insecticide, pesticide, repellant, disinfectant, and or air freshener as programmed. Control circuits allow the user to set when the system goes off.

The present invention provides for novel poisoning-resistant catalysts used for automobile exhaust gas treatment systems. To alleviate the detrimental affects of engine oil and / or fuel additive poisoning the present invention provides for an overcoat layer comprising a porous refractory oxide and one or more base metal oxides, which is coated over one or more precious metal containing washcoat layers. The overcoat of the present invention prevents phosphorous as well as other poisoning deposits, from fouling and / or negatively interacting with the underlying precious metal containing washcoats. In an alternative embodiment, the present invention provides for the coating of the upstream end of a catalytic member by the overcoat layer, thereby creating an upstream poison capture zone.

A method of modifying the content of certain chemical compounds in tobacco materials is provided, the method including treatment of a tobacco plant or portion thereof with at least one enzyme. For example, the method may modify the content of tobacco smoke toxicant precursors in tobacco materials, which can result in a modification in toxicant production when the tobacco material is exposed to elevated temperatures. The type of tobacco plant or portion thereof treated according to the invention can be, for example, a tobacco seed, a tobacco seedling, an immature live plant, a mature live plant, a harvested plant, or a plant derivative. Smoking articles and other tobacco products including such enzyme-treated tobacco materials are also provided.

The invention discloses a method which can carry out qualitative screening to 242 compounds (drugs or toxicants) simultaneously. A mode of liquid chromatogram-mass spectrometry (LC-MS / MS) multi-reaction monitoring (MRM) is adopted to carry out determinedness to objects by two pairs of parent ion-daughter ion pair and retention time. The 242 drugs or toxicants comprise toxic products such as opioids, amphetamine and cocaines and the like, bromazepam such as benzodiazepines and barbiturates, and common drugs, alkaloid, pesticide (including organophosphates, carbamates, pyrethroid pesticide residues and organochlorine pesticide), weed killer, raticide and the like.

The invention relates to a method for detecting unknown poison by establishing a liquid chromatography-mass spectrometry database, in particular to a method used for detecting unknown poison during food poisoning. According to the method, firstly, an ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry method is used for establishing a liquid chromatography-mass spectrometry database of common poison; then, a sample is subjected to supersonic extraction with methyl alcohol or acetonitrile, liquid chromatography-mass spectrometry data of an extracting solution are measured similarly and searched and compared in the liquid chromatogram-mass spectrometry database of common poison according to the retention time of the sample and mass spectrometry fragments, and the variety of the unknown poison in the sample is judged; and the unknown poisoning sample is simply extracted and directly measured and compared, and a screening result can be acquired in one hour, so that the detecting and treating time of the sample is greatly shortened, the detecting efficiency is improved, and technical support is provided for related events such as food poisoning and the like caused by unknown reasons.

The invention discloses a novel mesoporous material for adsorbing tar, phenol and special nitrosamine in tobacco and so on, in mainstream smoke of the tobacco. The mesoporous material with high adsorption property is used as an addition material for filter tips of cigarettes; and the mesoporous material is a mesoporous molecular sieve with a three-dimensional mesh microstructure and monolithic appearance such as SBA-15,or is a SBA-15 mesoporous molecular sieve material which is plated with a liquid film or is modified by metal oxides such as zirconia and is provided with the three-dimensional mesh microstructure and the monolithic appearance. The invention adopts a more convenient and effective method to develop the SBA-15 mesoporous molecular sieve material with the three-dimensional mesh microstructure and the monolithic appearance and modify the surface / a surface layer, has good performance of intercepting environmental toxins such as interception particulate phase matters and phenol in smoke, has the characteristics of saving energy, saving time, and reducing environmental pollution during the preparation, can also reduce cost, and has remarkable economic benefit and social benefit.

The subject invention pertains to materials and methods useful for management of certain pests. The invention is particularly well suited for the control of social insect pests and, particularly, termites. The invention concerns unique toxicant-containing matrices as well as apparatuses for monitoring pest activity and presenting a toxicant. The invention is useful as part of an Integrated Pest Management Program and can greatly reduce the introduction of harmful chemicals into the environment.

In a new pharmaceutical combination, the herb, Vitex agnus-castus (chasteberry), enhances hormone balance by increasing progesterone release and, therefore, ovulation frequency. The antioxidants, green tea, vitamin E, and selenium, improve overall reproductive health. L-arginine, an amino acid, stimulates the reproductive organs by improving circulation. Folic acid, vitamins B6 and B12, iron, zinc and magnesium help promote womens' fertility. Sperms are highly susceptible to free radical or oxidative damage from environmental toxicants and natural aging. Vitamins C and E, coenzyme Q10 and selenium are all potent antioxidants that help improve sperm counts and quality. Ferulic acid, an antioxidant found in Dong quai, also improves sperm quality. Zinc and B vitamins (B6, B12 and folate) are critical nutrients in male reproductive systems for hormone metabolism, sperm formation and motility. The amino acid, L-carnitine, promotes formation of healthy sperm.

A gas and water vapor pervious adsorption filter material having a protective function against biological and chemical noxiants and poisons and a multilayered layer construction including a first sheetlike carrier layer, a second sheetlike carrier layer and, interposed between the first carrier layer and the second carrier layer, an adsorbing layer, the adsorbing layer comprising an activated carbon fiber fabric which is durably adhered to the first carrier layer and to the second carrier layer by means of an adhesive.

A dual bait toxicant station includes a wick that can be moved to access a liquid reservoir, thereby activating the liquid feeding portion of the station. The wick can be selectively forced downward into the reservoir by activation of a lid which can have a bi-stable portion. The station may have a pie wedge-shaped top view, with multiple entrances along an arc portion of the station side.

Methods of treating a plant exposed to a phytotoxicant are provided. Embodiments of the subject methods include identifying a plant exposed to a phytotoxicant and applying an assimilable carbon-skeleton energy component-comprising composition to the identified plant. Embodiments of the subject compositions may include one or more of a macronutrient component, micronutrient component, vitamin / cofactor component, complexing agent and microbe. Kits for use in practicing the subject invention are also provided. The subject methods find use in a variety of different applications in which a plant is phytotoxic or at least in danger of becoming phytotoxic due to exposure or potential exposure to a phytotoxicant.

The invention discloses a drying preparation method of silicon dioxide aerogel under atmospheric pressure, using rice husk as raw material, which comprises the following procedures: (1) preparation of rice husk sol; (2) aging of gel; (3) solvent exchange; (4) surface modification of gel; (5) drying under atmospheric pressure. Instead of expensive toxicant organ silicon source, agricultural trashes rice husk is used as raw material, thus greatly reduce the cost; instead of super-critical drying, drying under atmospheric pressure greatly reduces the requirements for the whole process on the equipment, greatly improves the safety performance on one hand, also greatly reduces the running cost on the other. The method in the invention has the advantages of simple technology, easy operation, which is suitable for scale production.

This invention provides principles, methods and compositions for ascertaining the mechanism of action of pharmacologically important compounds in the context of network biology, across the entire scope of the complex pathways of living cells. Importantly, the principles, methods and compositions provided allow a rapid assessment of the on-pathway and off-pathway effects of lead compounds and drug candidates in living cells, and comparisons of lead compounds with well-characterized drugs and toxicants to identify patterns associated with efficacy and toxicity. The invention will be useful in improving the drug discovery process, in particular by identifying drug leads with desired safety and efficacy and in effecting early attrition of compounds with potential adverse effects in man.

An insecticide packet for killing biting insects comprises an envelope enclosing an insecticide and having a permeable web that is penetrable by the mouthparts of a biting insect. The permeable web allows insect attractants to migrate from within the envelope to the ambient environment. The envelope may be enclosed within an outer protective pocket. The insecticide packet is provided with a plurality of pins extending outwardly from the packet to discourage non-targeted animals from attempting to ingest the envelope or its contents. The packet is provided with a buoyant support arranged so that the permeable web is above the water line when the packet floats on the surface of a water body. The insecticide includes a stomach poison mixed with a liquid food that is preferred by the biting insects, such as cattle blood. Volatile insect attractants may be added to the mixture of stomach poison and food.

The invention, belonging to the field of paints, discloses a low surface energy nano polyurethane anti-fouling paint and a preparation method thereof. The paint is mainly applied in preventing fouling for ships. The low surface energy nano polyurethane anti-fouling paint comprises 20-60 wt% of organosilicon modified acrylic resin, 0.5-10 wt% of polydimethylsiloxane resin, 0.5-10 wt% of fluoroal kylsilane modified nano silicon dioxide, 20-40 wt% of extender pigment, 5-15 wt% of auxiliary agent, and 10-30 wt% of organic solvent. The preparation method comprises the following steps: 1) carrying out surface treatment with fluoroal kylsilane on nano silicon dioxide; 2) preparing the treated fluoroal kylsilane modified nano silicon dioxide into a concentrated slurry; and 3) mixing the fluoroal kylsilane modified nano silicon dioxide concentrated slurry with other raw materials to obtain a component A of the anti-fouling paint; dissolving a curing agent to obtain a component B, adding the component A in the component B, curing 30 min-15 day at a temperature of 10-30 DEG C to form the low surface energy nano polyurethane anti-fouling paint. The anti-fouling paint prepared by using a new technique of nanoparticle treatment has the advantages of low surface energy, no toxicant release, safety, and environmental protection.

The invention discloses herbal tea for improving human immunity. The herbal tea comprises the following composition by weight: 1-5 parts of tea leaf, 2-19 parts of mulberry leaf, 5-20 parts of chrysanthemum, 3-8 parts of henom bamboo leaf, 2-20 parts of white hyaciath bean flower, 3-6 parts of lotus leaf and 5-15 parts of pagodatree flower. The herbal tea has a prescription of neutral edible medicines and has no cool or hot property. Vegetable foods play functions of moisturizing intestines, detoxifying, eliminating toxicant and diuresis, relieving inflammation, activating blood circulation to dissipate blood stasis and improving immunity on subjects after neutralizing with each other; the herbal tea is designed according to holistic medical care of traditional Chinese medicine and made from raw materials of herb-food-homologous vegetable foods. According to different prescription methods of monarch, minister, assistant and guide, the herbal tea has different preventative and curative effects on diseases.

A termite monitoring and baiting station (10) has a housing (20), with a removable cover (30), defining a cavity (24) to receive one or more pieces of termite attractant material (50), eg., mountain ash. The termite attractant material (50) may partially extend outwardly through holes (26,28) in the side wall (21) of the container (20) and has grooves (53) to increase the effective surface area and to provide tracks for the termites. When termite activity is noted, a termite toxicant bait (60) is placed in the cavity (24), to enable the termites to carry the bait material (62) back to their colonies.

The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention utilizes materials taken from the EPA's GRAS (Generally Recognized as Safe) List for this purpose. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the area during coating application, thereby eliminating the need for topical insect repellants such as DEET.

The invention discloses an environmental protection adhesive for timber industry, prepared of a formula comprising: PVA 5-10wt%, silica solution 10-20wt%, glycol 0.2-0.35wt%, polyacrylamide 0.03-0.05wt%, mildew- proof germicide 0-0.1wt%, fillings 10-12wt%, and water the rest. It does not use aldehyde-containing, hydroxybenzene-containing and organic volatile-containing matters as raw materials to form a formula, and the used raw materials have wide sources but no poisonous matters, and besides, these components can excellently cooperate with one another, therefore it has excellent performances of three-aldehyde glue and radically solves a series of problems caused by formaldehyde and organic volatile release.

Described herein are compositions and methods for capturing carbonylic or phenolic toxicants, or converting these toxicants into less volatile compounds. The toxicants, which may be a component of cigarette smoke, may be captured by physical or chemical adsorption, absorption, or entrapment.

The invention discloses a mycotoxin degrading adsorbent, which contains bacillus subtilis, lactobacillus plantarum, lactobacillus acidophilus, leuconostoc lactis, lactobacillus delbrueckii, lactobacillus fermenti, lactobacillus salivarius, vitamin C, vitamin E, radix astragali, zinc methionine, potassium chloride, cassia bark, clove, oriental wormwood, folium artemisiae argyi, sweet wormwood, wild chrysanthemum flower, semen plantaginis, yeast cell wall and phytase. The mycotoxin degrading adsorbent disclosed by the invention has multiple effects including generation inhabitation, degradation and adsorption on various common mycotoxins, and can additionally boost immunities of pigs and promote excretion of toxic substances; the mycotoxin degrading adsorbent has excellent comprehensive performance and plays a remarkable role on productivities of piglets, and the mycotoxin degrading adsorbent can reduce disease rate, improve daily gain, increase feed digestibility and reduce feed conversion ratio. Moreover, the mycotoxin degrading adsorbent is low in dosage but effective and free from adsorption on drugs and other nutrient substances, and the adsorbent can be biologically degraded after being secreted and avoid pollutants; and the mycotoxin degrading adsorbent has good application value in breeding industry.

The invention discloses achromobacter xylosoxidans subsp.xylosoxidans LH-N25 with CGMCC No.6972. The invention also discloses a heterotrophic nitrification and aerobic denitrification microorganism bactericide. The microorganism bactericide comprises achromobacter xylosoxidans subsp.xylosoxidans LH-N25 or also comprises paracoccus aminovorans LH-N40; and the strains are combined according to any ratio. The invention also discloses a preparation method of the microorganism bactericide. The microorganism bactericide disclosed by the invention not only can solve the problem that total nitrogen cannot be easily removed in the traditional reactor, but also can effectively remove ammonia nitrogen and total nitrogen in a water body in the same reactor, and has tolerance and degradation ability on the toxic substances such as phenols, amines, hetercyclics, cyanogens and polyaromatic hydrocarbon in the wastewater at the same time. The microorganism bactericide is especially suitable for chemical wastewater containing nitrogen, is simple in treatment process, stable in effect, and resistant to impact of environmental toxic substances, and has a wide application prospect in treatment of chemical wastewater containing nitrogen.

A method to detect the acute biology toxicity by the photobacterium is to prepare the new photobacterium culture firstly, then to adjust the pH of tested water: the pH is 4.5 when the Cu density is higher than other metal and organic matter; the pH is 5.4 when the water sample does not contain Cu and other metal density is higher than the organic matter; the pH is 7.0 when the organic matter in water is higher than metal density. The ZnSO4 is as reference toxicity and matching a series of standard solution which are set in tube which is added in the photobacterium culture and detect the relative luminance. The luminance change of test water is expressed by the relative luminance. The computing formula is: the sample relative luminance = sample tube luminance / reference tube luminance. The invention uses the photobacterium not the toxicity to detect the acute biology toxicity of water.

The invention concerns a functional apparel item, in particular protective apparel having a protective function against biological and / or chemical toxicant or noxiant materials, the apparel item being equipped with a measuring appliance capturing at least one measurable quantity and adapted for determining the serviceability of the apparel item.

The invention belongs to the field of water treatment, and discloses a method for intensifying the activity of anammox microorganism by the fixed effect of the active carbon. The method mainly comprises the steps of: soaking the active carbon by anammox-based inorganic salt solution, adding the treated active carbon and anammox sludge into the anammox-based inorganic salt solution, and cultivating to obtain the anammox microorganism which is stably coupled to the active carbon. Aiming the waste water with low carbon nitrogen ratio, the invention provides a technology which takes the active carbon as a carrier, intensifies the activity of the anammox microorganism, and resists the influence caused by the bad environment. The method can run for a long time more stably, can and accord with the condition for practically running and managing a sewage plant. The active carbon has a certain capability for absorbing the organic matter, so that the influence to the anammox sludge caused by the organic matter and the other toxic matters is reduced, and the execution of the anammox reaction is intensified.

The invention provides methods for analyzing and predicting the in vivo respiratory toxicity of a compound (e.g., pharmaceutical, biological, cosmetic, or chemical compounds) or composition comprising a combination of an in vitro mammalian cell model with multiple endpoint analysis, and time and concentration response curves. The methods allow the determination of a predicted in vivo respiratory toxicity value of a compound without the use of animals, with a high degree of accuracy. The methods comprise detecting any combination of cell viability markers and expression levels of genes implicated in respiratory toxicity and / or sensitization, such as pro-inflammatory response genes, combining the viability and gene expression level data with concentration response and time response data, conducting a computational analysis, and comparing test compound data to a database of known respiratory toxicants / sensitizers to predict and / or analyze the respiratory toxicity. An indication of organ specificity is provided by a toxicity index, which is determined by comparing mean IC50 values in lung cells to mean IC50 values in liver cells.