The invention discloses a production method of biological organic compound fertilizer and belongs to the biological organic field. According to the production method, chicken manure is taken as the main material, crop straw, straw, peanut shell, sawdust, mixture of rice chaff and husk, brewers grain, starch pulp, cottonseed meal, Chinese trumpet creeper and the like are taken as auxiliary material, and the organic fertilizer is produced through a method of adding strain and sufficient digesting. The method has the advantages of low production cost, completeness in fermentation and sterilization, high biological activity and fertilizer efficiency, odourlessnes, asepsis and convenience in use, can improve soil physical and chemical properties, enhances the soil water retention, fertilizer maintenance and fertilizer feeding capacities, increases beneficial bacterium and soil microorganism and population, and ensures that the yield of grain crop, industrial crop, vegetables and melons and fruits is greatly increased.