46 results about "Aqueous extract" patented technology

The disclosure relates to a continuous process for obtaining phosphoric acid and calcium sulphate dihydrate from apatite, and sulphuric acid using hydrochloric acid as an intermediate attacking agent, comprising the steps: Leaching (101) apatite (11) with an aqueous solution of hydrochloric acid (12,13) to solubilize phosphorus compounds contained in the apatite, thereby obtaining a solution (15) containing phosphate (H3PO4) and calcium chloride (CaCl2); extracting (103) said solution (15) with organic solvent (16), yielding an organic extract (17) loaded with phosphate ions, and an aqueous raffinate (21) containing calcium chloride and residual impurities; re-extracting the phosphate ions from the organic extract (17) with water (18), thus yielding an aqueous extract (19) of phosphoric acid, and an unloaded organic phase substantially free of phosphoric acid, reacting (107) the raffinate (21) containing calcium chloride with sulphuric acid (26) to cause precipitation of calcium ions in the raffinate as calcium sulphate dihydrate and to recover chloride ions in the raffinate in the form of hydrochloric acid (12), wherein the reaction of the raffinate (21) containing calcium chloride with sulphuric acid (26) involves intermittent agitation of the raffinate, filtering off (108) precipitated calcium sulphate dihydrate (27) from the previous step (107) and washing it with water, recycling (112) the recovered hydrochloric acid (12) to the step (101) of the leaching apatite.

The application discloses a sunscreen composition based on the ultraviolet absorption characteristics of yellow water of liquor, and a preparation method and application thereof. The sunscreen composition comprises 10-60 parts by weight of a yellow water extract of a strong-flavor liquor, 20-70 parts by weight of a yellow water extract of a Maotai-flavor liquor, and 0-40 parts by weight of a yellow water extract of a light-flavor liquor. It is found that the yellow water of different flavor liquors has characteristic ultraviolet absorption spectrum, wherein the yellow water of the strong-flavor liquor has strong absorption in the UVB band (290-320 nm), the yellow water of the Maotai-flavor liquor has strong absorption in the UVA band (340-380 nm), and the yellow water of the light-flavor liquor has relatively uniform absorption in a wide band. According to the spectral complementarity, the natural sunscreen composition is obtained. The sunscreen composition has an in-vitro SPF value of 15-35, a PA value of ++~++++, good light stability and low skin irritation.

This invention provides a mulberry leaf and wolfberry composition, comprising aqueous extracts of wolfberry, mulberry leaves, astragalus, yam, kudzu root, and green tea. This invention also provides oral preparations and food products containing this composition. Furthermore, this invention provides the application of the composition or oral preparation in the preparation of health foods that help maintain healthy blood sugar levels and hypoglycemic drugs. The composition provided by this invention has the effect of lowering blood sugar, and the selected raw materials are highly safe, have few toxic side effects, and are widely available, possessing significant market value and development prospects.

This invention provides an extract of *Hedyotis diffusa*, its preparation method, and its uses. When the extract is measured under reversed-phase high-performance liquid chromatography, the peak area A of 6''-malonyl *Hedyotis diffusa* I is... M Peak area A with cypermethrin I B The ratio is less than 0.1, and the peak area A of free kaempferol is... K With A B The ratio shall not exceed 0.15. The preparation method includes: adjusting the pH of the aqueous extract of *Kaempferia galanga* to 11-13.5, and performing alkaline hydrolysis at 25-65°C for 20-60 minutes. This invention utilizes the difference in stability of malonyl bonds and glycosidic bonds under alkaline conditions to achieve the selective conversion of 6''-malonylkaempferol I to kaempferol I, increasing the content of kaempferol I while maintaining the integrity of the glycosidic bonds and inhibiting or controlling the formation of free kaempferol. The resulting extract can be used to prepare anti-inflammatory and antioxidant drugs or health foods.

The application belongs to the technical field of biocontrol preparation, and particularly relates to a traditional Chinese medicine composition, a biocontrol preparation and application in the field of pearl plant leaf spot nematode disease prevention and treatment. The leaf spot nematode disease is a main disease and pest of pearl plant planting, and there is no effective prevention and treatment method at present. The application provides a traditional Chinese medicine composition, which comprises wolfberry, leigongteng, peppermint, phellodendron, boerhaavia diffusa and chamomile. Water extracts of the above-mentioned medicinal ingredients can effectively reduce the number of nematodes in soil and improve the disease resistance of pearl plants when used for pearl plant irrigation. The research results of the application are helpful for restraining the occurrence of pearl plant leaf spot nematode disease through biological prevention and control means, and provide theoretical guidance for the development of pearl plant green industry.

This invention belongs to the field of traditional Chinese medicine technology, and provides the application of Scutellaria baicalensis leaf aqueous extract in the preparation of drugs for improving or treating inflammatory bowel disease (IBD) with depression. The Scutellaria baicalensis leaf aqueous extract improves IBD with depression by increasing the abundance of Akkermansia myxophilus (AKK) bacteria, restoring disordered deoxycholic acid metabolism. The extract increases the abundance of AKK bacteria in the intestine, increases the content of deoxycholic acid (DCA) in the intestine, regulates Th17 / Treg homeostasis, reduces intestinal inflammation, maintains intestinal barrier integrity, reduces the entry of pro-inflammatory factors into the bloodstream and across the blood-brain barrier into the hippocampus, inhibits neuroinflammation, and improves depression. Scutellaria baicalensis leaves can improve IBD with depression by increasing the abundance of AKK bacteria in the intestine, increasing intestinal DCA levels, regulating Th17 / Treg balance, repairing the intestinal barrier, reducing LPS leakage and alleviating nerve damage, and inhibiting the inflammatory response of the gut-brain axis. This provides certain experimental evidence for the development and utilization of related traditional Chinese medicine resources.

This invention relates to the field of Astragalus processing technology and discloses a method for drying Astragalus extract. The method involves adding a drying dispersant to the Astragalus extract and then spray drying it. The drying dispersant is β-cyclodextrin or the residue after Astragalus extraction. In this invention, spray drying is used to dry the Astragalus aqueous extract, and a dispersant (β-cyclodextrin or residue) is added to the system to be dried. Practical verification shows that the inlet air temperature can be controlled at around 130℃, which improves drying efficiency. Furthermore, the yield after drying, based on the calculated solids content, can reach over 95%.

The disclosure relates to a continuous process for obtaining phosphoric acid and calcium sulphate dihydrate from apatite, and sulphuric acid using hydrochloric acid as an intermediate attacking agent, comprising the steps: Leaching (101) apatite (11) with an aqueous solution of hydrochloric acid (12,13) to solubilize phosphorus compounds contained in the apatite, thereby obtaining a solution (15) containing phosphate (H3PO4) and calcium chloride (CaCl2); extracting (103) said solution (15) with organic solvent (16), yielding an organic extract (17) loaded with phosphate ions, and an aqueous raffinate (21) containing calcium chloride and residual impurities; re-extracting the phosphate ions from the organic extract (17) with water (18), thus yielding an aqueous extract (19) of phosphoric acid, and an unloaded organic phase substantially free of phosphoric acid, reacting (107) the raffinate (21) containing calcium chloride with sulphuric acid (26) to cause precipitation of calcium ions in the raffinate as calcium sulphate dihydrate and to recover chloride ions in the raffinate in the form of hydrochloric acid (12), filtering off (108) precipitated calcium sulphate dihydrate (27) from the previous step (107) and washing it with water, dividing (113) the remaining hydrochloric acid (12) aqueous solution into a primary stream (12a) and a secondary stream (12b); and recycling (112) the primary stream (12a) of the aqueous solution of hydrochloric acid (12) to the step (101) of the leaching apatite, and at least partially removing the secondary stream (12b) from the process.

This invention provides a Brazilian ginseng-guarana encapsulated aqueous extract, its preparation method, and its application, belonging to the field of anti-fatigue product development technology. The preparation method of the Brazilian ginseng-guarana encapsulated aqueous extract includes: mixing Brazilian ginseng and guarana at a mass ratio of 1:9, adding water for ultrasonic-enzyme pretreatment, extracting and concentrating after pretreatment to obtain the Brazilian ginseng-guarana encapsulated aqueous extract; encapsulating the Brazilian ginseng-guarana encapsulated aqueous extract, and freeze-drying to obtain the Brazilian ginseng-guarana encapsulated aqueous extract. This invention combines ultrasonic-enzyme synergistic pretreatment with optimized encapsulation technology to simultaneously improve the dissolution rate, stability, and bioavailability of the active ingredients of Brazilian ginseng and guarana. The process is simple, cost-controllable, and suitable for large-scale production.

This application relates to the technical field of important veterinary preparations and discloses a preparation process for a compound traditional Chinese medicine granule preparation for veterinary use, including the following steps: (1) extracting dandelion, indigo leaf, isatis root, honeysuckle, licorice, patchouli, and gypsum with water to obtain an aqueous extract; adding scutellaria and phellodendron to the residue after water extraction and extracting with alcohol to obtain an alcohol extract; combining the extracts and concentrating to obtain a clear extract; (2) first mixing hydroxypropyl-β-cyclodextrin and sulfobutyl ether-β-cyclodextrin to obtain a mixed cyclodextrin solution, adding glycyrrhizic acid for pre-inclusion to form a glycyrrhizic acid-cyclodextrin pre-inclusion complex; then adding the obtained clear extract to continue inclusion to form an inclusion complex suspension; (3) mixing the inclusion complex suspension with pharmaceutical excipients, granulating and drying to obtain the final product. This application can improve the inclusion rate of baicalin and berberine and improve storage stability.

The disclosure relates to a continuous process for obtaining phosphoric acid and calcium sulphate dihydrate from apatite, and sulphuric acid using hydrochloric acid as an intermediate attacking agent, comprising the steps: Leaching (101) apatite (11) with an aqueous solution of hydrochloric acid (12,13) to solubilize phosphorus compounds contained in the apatite, thereby obtaining a solution (15) containing phosphate (H3PO4) and calcium chloride (CaCl2); extracting (103) said solution (15) with organic solvent (16), yielding an organic extract (17) loaded with phosphate ions, and an aqueous raffinate (21) containing calcium chloride and residual impurities; re-extracting the phosphate ions from the organic extract (17) with water (18), thus yielding an aqueous extract (19) of phosphoric acid, and an unloaded organic phase substantially free of phosphoric acid, reacting (107) the raffinate (21) containing calcium chloride with sulphuric acid (26) having a concentration of 1-12.5 M to cause precipitation of calcium ions in the raffinate as calcium sulphate dihydrate and to recover chloride ions in the raffinate in the form of hydrochloric acid (12), filtering off (108) precipitated calcium sulphate dihydrate (27) from the previous step (107) and washing it with water, recycling (112) the recovered hydrochloric acid (12) to the step (101) of the leaching apatite.

This invention relates to the field of mosquito repellent composition technology, specifically to a plant-based mosquito repellent composition and its preparation method, comprising Sophora flavescens extract, eucalyptol, montmorillonite glycol, and natural Echinacea purpurea extract; the natural Echinacea purpurea extract is an aqueous extract with a chicoric acid content ≥4%. The plant-based mosquito repellent composition and preparation method of this invention, through functional optimization of single components and synergistic formulation of multiple components, fundamentally solves the core problems of existing plant-based mosquito repellent products, such as poor mosquito repellent effect, short effective duration, and lack of skin soothing function, while also taking into account the product's naturalness and safety. Because a combined low-temperature enzymatic hydrolysis-stepwise alcohol extraction-microfiltration purification process is used to prepare the Sophora flavescens extract, and natural menthol extract is added as a drug guide, the extraction rate and utilization efficiency of plant active ingredients are effectively improved, reducing the waste of plant resources. Furthermore, the preparation process is green and environmentally friendly, generating no harmful waste.

This invention relates to the field of cosmetic technology, specifically to a collagen-containing repair and anti-aging composition, skincare products, and their applications. The composition, by weight, comprises: 0.5-4 parts recombinant collagen, 1-10 parts Polygonatum odoratum extract; preferably, it also includes 1-4 parts Anoectochilus roxburghii extract, with a more preferred weight ratio of 2:2:6. The Anoectochilus roxburghii extract is preferably an alcohol extract, and the Polygonatum odoratum extract is preferably an aqueous extract. This invention utilizes the combination of Polygonatum odoratum aqueous extract and Anoectochilus roxburghii alcohol extract to exert potent antioxidant and anti-wrinkle activities. This scientific combination not only significantly improves the transdermal absorption rate of recombinant collagen, overcoming the difficulty of large molecules penetrating the skin, but also achieves a balance between penetration enhancement and anti-aging effects, showing excellent application prospects in the cosmetic field.

This invention discloses a method for preparing microbial fertilizer using medicinal plant residues, belonging to the field of microbial fertilizer technology. The method includes: pretreating the medicinal plant residues and adjusting their moisture content and nutrient balance to obtain a material to be detoxified; sampling and preparing an aqueous extract during aerobic fermentation; selecting at least two indicators from maturity and phytotoxicity, salt content, and inhibitory marker residues to set release thresholds; ending fermentation when the thresholds are reached in a single sampling to obtain a detoxification matrix; cooling the detoxification matrix; contacting the aqueous extract or leaching with a porous adsorption carrier to adsorb residual inhibitory components to form a pre-adsorption carrier; loading and immobilizing bacterial agents to obtain microbial carrier bacteria; granulating the detoxification matrix and enriching the carrier bacteria on the surface of the particles; and drying to obtain microbial fertilizer. This invention achieves controllable detoxification and improves the colonization and storage stability of the microorganisms.

This invention discloses the application of Terminalia chebula in the prevention and treatment of Ichthyophthirius multifiliis (white spot disease) in aquatic animals. Toxicity experiments on grass carp kidney cells (CIK) showed that the maximum non-toxic concentration (NDC) of the aqueous extract of Terminalia chebula against CIK cells was 500 μg / mL. The inhibition of Ichthyophthirius multifiliis predator survival by the aqueous extract was dose-dependent, and the predator mortality rate reached 100% at a concentration of 100 mg / L (μg / mL). Furthermore, the median lethal concentration (LD50) of the aqueous extract against Ichthyophthirius multifiliis predators was calculated to be 14.577 mg / L. This invention is the first to propose the application of Terminalia chebula in inhibiting the survival rate of Ichthyophthirius multifiliis predators in fish at a non-toxic concentration to cells, providing a novel drug for the prevention and treatment of Ichthyophthirius multifiliis infection in aquatic animals. Terminalia chebula is a natural medicinal plant, environmentally friendly, and has the advantages of reducing the risk of drug residues.

This invention discloses an extract of *Taxus chinensis* aril and its application. The extract is obtained through the following steps: 1) thoroughly crushing the *Taxus chinensis* aril using a mortar and pestle; 2) extracting with water and ethanol as solvents, followed by rotary evaporation to obtain the mother liquor; 3) diluting the mother liquor to the desired concentration. Experimental results show that treatment with a 0.3 g / mL concentration of the aqueous extract of *Taxus chinensis* aril can inhibit the growth of barnyard grass in rice paddies, providing a research basis for the development of biological herbicides. Therefore, this invention provides a feasible method for studying the allelopathic effects of *Taxus chinensis* aril on barnyard grass and rice, and has practical application value.

This invention belongs to the field of traditional Chinese medicine technology, and provides a compound traditional Chinese medicine extract for lowering uric acid, its preparation, and application. Using hawthorn, astragalus, poria cocos, jujube, and tangerine peel as raw materials, this invention obtains ethanol extract S1 and water extract S2 through ethanol extraction and water extraction. Both S1 and S2 have antioxidant activity, targeting DPPH and ABTS. + The free radicals exhibit significant scavenging capabilities and can effectively inhibit xanthine oxidase activity. Furthermore, S1 and S2 can reduce serum and liver XOD activity in hyperuricemic mice, improve liver and kidney function indicators such as AST, ALT, TP, UREA, SCr, and CysC, and decrease serum uric acid levels in a dose-dependent manner; high doses can lower uric acid levels below normal. The extract of this invention possesses uric acid-lowering, antioxidant, and liver and kidney protective effects, showing good therapeutic effects on hyperuricemia and good protective and preventive effects against liver and kidney damage caused by hyperuricemia.

The invention is directed to an aqueous extract of Eruca sativa (arugula) leaves that has antimicrobial activity on Gram-positive bacteria and mycoplasmas. The extract may be purified away from solid or insoluble components, standardized based on the weight of its non-aqueous or solid content, assayed for antimicrobial activity, and provided in an aseptic or sterile form for pharmaceutical use. It may be used to kill or inhibit the growth of microorganisms such as Gram positive bacteria, promote wound healing, or as prophylaxis against host colonization or infection by a microorganism.

This invention relates to a method for preparing a kapok flower extract. The method includes the following steps: mixing kapok flower raw materials with an ionic reagent and extracting under a high-voltage pulsed electric field; centrifuging, filtering, and collecting the filtrate to obtain the kapok flower extract; the ionic reagent is obtained by reacting glycerol and betaine. This invention utilizes a natural ionic reagent combined with a high-voltage pulsed extraction method. First, a high-voltage pulsed electric field is used to induce biomembrane permeation, causing the relevant active substances in the kapok flower to dissolve. Simultaneously, the ionic reagent can effectively improve the extraction efficiency of relevant active ingredients in the kapok flower. Compared with conventional water extracts, the extract prepared by the process provided by this invention has a significantly increased content of active ingredients and also possesses advantages such as antibacterial, antioxidant, and long shelf life. When applied to skincare products, it can effectively resist oxidation, improve skin radiance, and delay skin aging.

This invention discloses a drug extract for enhancing the efficacy of porcine reproductive and respiratory syndrome (PRRS) vaccines, its preparation method, and its application. The drug extract comprises aqueous extracts of Astragalus membranaceus and Curcuma zedoaria, wherein the optimal mass ratio of Astragalus membranaceus to Curcuma zedoaria is 4-5:1. The Astragalus membranaceus and Curcuma zedoaria extract of this invention enhances the efficacy of existing PRRSV vaccines, improves vaccine resistance to PRRSV, and effectively stimulates the body to produce sufficient neutralizing antibodies, thereby enhancing the overall immune effect of the vaccine, with significantly better results than using the vaccine alone.

This invention discloses a mixed-culture fermented Polygonatum sibiricum compound granule and its preparation method, belonging to the technical field of modern processing of traditional Chinese medicine and development of functional foods. The method includes: screening Lactobacillus casei, Lactobacillus fermentum, and Monascus purpureus as a mixed-culture combination based on the CRITIC-WASPAS multi-index comprehensive evaluation method; inoculating the mixed-culture combination into Polygonatum sibiricum culture medium to obtain Polygonatum sibiricum fermentation broth; compounding the Polygonatum sibiricum fermentation broth with aqueous extracts of sweet tea, Eucommia ulmoides, white kidney bean, and Litsea cubeba, and adding low-chain inulin, pea protein peptides, and gellan gum as co-solvents to obtain a compound solution; and freeze-drying to obtain the mixed-culture fermented Polygonatum sibiricum compound granule. This invention objectively screens dominant strains through a multi-index comprehensive evaluation method, and the compound system and co-solvents synergistically enhance the effect, improving the utilization rate of active ingredients. The resulting granule dissolves rapidly, disperses evenly, and has good antioxidant, hypoglycemic, and lipid-lowering activities.

This invention discloses a formula and preparation method of a liver-protecting, lipid-lowering, and hangover-relieving nutritional tablet based on pecinosyl glycosides. The formula comprises 5-30 parts of rice bran fatty alkanol, with octacosanol as the main component; 10-50 parts of Gastrodia elata water extract, with a gastrodin content of not less than 0.5%; 20-80 parts of a natural product water extract rich in dihydromyricetin, with a dihydromyricetin content of not less than 5%; 10-50 parts of Prunus mume water extract; 1-10 parts of taurine; and 1-5 parts of B vitamins, with B1, B2, and B6 as the main components in a 1:1:1 mass ratio. This invention uses pecinosyl glycosides as the core, combining medicinal and edible raw materials with new food ingredients, following scientific compounding principles. The active ingredients work synergistically to achieve multiple effects, including improving energy metabolism, lowering blood lipids, and protecting the liver and relieving hangovers. The effects are superior to those of single-component formulations, and it can specifically address various metabolic sub-health issues in modern populations.

This invention discloses a method for preparing an aqueous extract of Artemisia argyi and its application, particularly in the preparation of drugs for treating allergic contact dermatitis. The preparation method includes step 1: naturally air-drying harvested Artemisia argyi leaves, followed by mechanical pulverization to obtain Artemisia floss raw material; step 2: mixing the Artemisia floss raw material with pure water, soaking at room temperature, extracting with ultrasound assistance, combining the extracts, decocting in a water bath, concentrating under reduced pressure, and freeze-drying to obtain the Artemisia argyi aqueous extract. This invention provides an Artemisia argyi aqueous extract, its preparation method, and its application. This Artemisia argyi aqueous extract has significant anti-allergic and anti-irritant effects, effectively inhibiting hyaluronidase activity, reducing erythrocyte hemolysis rate, and exhibiting good therapeutic effects on 2,4-dinitrofluorobenzene-induced allergic contact dermatitis. It also has high bioavailability and good safety. This invention lays an important foundation for developing efficient and safe natural anti-allergic products.

This application provides the use of protocatechuic acid in the preparation of medicaments for the prevention and treatment of respiratory syncytial virus (RSV) infection, and also provides the use of an aqueous extract of Cyperus rotundus containing protocatechuic acid in the preparation of medicaments for the prevention and treatment of RSV infection, as well as pharmaceutical compositions for the prevention and / or treatment of RSV infection and their uses. The aqueous extract of Cyperus rotundus and its component protocatechuic acid provided in this application have anti-RSV activity, and can therefore be used to prevent and / or treat RSV infection, and further for the preparation of medicaments for the prevention and / or treatment of RSV infection.

The present invention describes the synthesis and use of nanoparticles derived from the leaves of Globularia alypum, a medicinal plant native to the Gafsa region, known for its therapeutic properties. This invention makes it possible to utilize the active compounds of this plant in nanoparticle form in order to improve their efficacy and bioavailability for the treatment of gastrointestinal disorders, particularly constipation. The aqueous extract of Glohularia alypum leaves contains bioactive compounds that act on the digestive system, thus facilitating intestinal transit and reducing constipation. Simultaneously, the use of AgNG allows for better absorption of the active compounds by the body. The preparation process for AgNGs involves mixing the aqueous extract of Glohularia alypum with an Ag NO3 solution and incubating for 15 minutes at 60°C.

This invention relates to the field of pharmaceutical technology, specifically to a combination of traditional Chinese medicine (TCM) preparations for antibacterial and health-promoting treatment throughout the entire life cycle, and its method of use. The kit comprises three independent preparations: a rapid-release protective spray using Litsea cubeba essential oil nanoemulsion as a solvent, loaded with a compound alcoholic extract derived from Polygonum cuspidatum, Senecio scandens, Clematis chinensis, and Glycyrrhiza uralensis in a weight ratio of 4:3:1:1; a sustained-release repair gel patch using a thermosensitive poloxamer F127 and gelatin-sodium alginate double-network hydrogel as a matrix, encapsulating a concentrated aqueous extract obtained from freeze-dried powders of Polygonum cuspidatum, Portulaca oleracea, dried ginger, Bletilla striata, and honey in a weight ratio of 4:2:1:2:1; and a soluble healing-promoting bath film, a biodegradable film made from polyvinyl alcohol and carboxymethyl chitosan via a casting method, in which ultrafine powders of the core active pharmaceutical ingredient and nano-silver-bioglass composite material are dispersed. This application aims to construct a multi-layered, responsive product system from rapid protection to deep repair.

This invention discloses a kombucha-fermented acorn jelly rich in prebiotics, comprising, per 100 parts by weight: 40-70 parts by weight of acorn fermentation broth, 3-15 parts by weight of isomaltooligosaccharide, 1-16 parts by weight of purple sweet potato anthocyanin aqueous extract, 6-22 parts by weight of a composite coagulant, and the remainder being water. The invention also discloses its preparation method. This invention reduces the bitterness and astringency of acorns and enriches their flavor through kombucha fermentation; by adding prebiotics (purple sweet potato anthocyanins and isomaltooligosaccharide) for coloring and flavoring, it enhances both the sensory quality and health benefits of the acorn jelly; and by preparing a low-temperature composite coagulant, which eliminates the need for heating, it maximizes the preservation of probiotic activity in the jelly, further enhancing its intestinal health-improving effects. The method of this invention yields a fermented acorn jelly product that combines prebiotics and probiotics. This invention provides technical support for the development of high-value-added acorn foods.