212 results about "Aqueous extract" patented technology

The invention discloses a construction method and application of a specific chromatogram of a vinegar trogopterus dung water extract. The construction method of the specific chromatogram of the water extract of trogopterus dung processed with vinegar comprises the following steps: mixing the water extract of trogopterus dung processed with vinegar with an extraction solvent, and extracting to prepare a test solution; and performing high performance liquid chromatography analysis on the test solution, and constructing the characteristic spectrum of the vinegar trogopterus dung water extract. The construction method of the specific chromatogram of the vinegar trogopterus dung water extract is high in precision, has repeatability and stability, and can provide more abundant characteristic peak information, so that the sample quality can be reflected more comprehensively.

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight through the following method: taking 15 parts of astragalus membranaceus, 6 parts of rhizoma anemarrhenae, 6 parts of cortex phellodendri, 4 parts of angelica sinensis, 3 parts of cinnamon, 5 parts of liquorice and 5 parts of ampelopsis grossedentata vines, adding water of which the weight is 10 times of the total weight of the raw material medicines, soaking for 0.5 hour, and performing reflux extraction twice for 1.5 hours each time; in the extraction process, Chinese angelica and cinnamon aromatic water which is equivalent to two times of the volume of the prescription is collected for later use; concentrating the water extract at 60-80 DEG C under reduced pressure, and drying to obtain a dry extract; preparing an inclusion compound from aromatic water by using beta-cyclodextrin, drying and crushing; and uniformly mixing the dry extract with the aromatic water beta-cyclodextrin inclusion compound. The invention further discloses a lipstick containing the composition and application of the lipstick.

The invention relates to the technical field of preparation of cured beef, and discloses low-salt cured beef which comprises main materials and auxiliary materials in parts by mass as preparation raw materials, the main materials comprise fresh yellow cattle meat and compound salt, and the auxiliary materials comprise tea polyphenol, alanine, calcium gluconate and a kelp powder aqueous extract. The formula comprises 100 parts of fresh yellow cattle meat, 5 parts of compound salt, 0.1 part of tea polyphenol, 0.2 part of alanine, 0.5 part of calcium gluconate and 1 part of kelp powder aqueous extract. The method comprises the following steps: putting cleaned beef strips into a microwave oven, mixing 5% of compound salt with tea polyphenol, anthocyanin, rosemary extract, alanine and calcium gluconate in order to improve the pickling efficiency, adding 50 parts of clear water, and uniformly stirring to prepare a pickling solution; and cooling the fried cured beef to room temperature, packaging with a vacuum packaging bag, and carrying out ultrahigh pressure treatment (300MPa, 5 minutes) to replace irradiation, prolong the shelf life and retain the flavor, so that the method has the advantages of traditional flavor, prolonged shelf life, simple production process and the like.

The method for stimulating the defenses of a plant or tree against an infection of bacterium or fungus comprises the application on the plant or tree of an aqueous extract from at least leaves of a Rocket plant. The application on the plant or tree is achieved by foliar spray. The extract is obtained by grinding the Rocket plants in an aqueous medium, filtering the ground material obtained and recovering the liquid extract of Rocket plants obtained after filtering.

The invention discloses a traditional Chinese medicine compound preparation for treating insomnia and a preparation method thereof, the traditional Chinese medicine compound preparation is prepared from the following raw materials or alcohol and water of the following raw materials or water extract or honey-processed paste: 15-30g of lily, 15-30g of lucid ganoderma, 15-90g of vine of multiflower knotweed, 30-60g of cortex albiziae, 30-60g of nacre mother of pearl, 6-15g of coptis chinensis, 15-30g of spina date seed, 30-60g of poria with hostwood, 6-15g of polygala tenuifolia and 30-60g of magnetite. The preparation method comprises the following steps: uniformly mixing 30-60 g of lapis chloriti, 30-60 g of ligusticum wallichii, 10-15 g of schisandra chinensis, 3-10 g of cinnamon, 15-30 g of salvia miltiorrhiza, 30-60 g of oyster, 15-30 g of platycladi seed, 15-30 g of corydalis tuber and 15-30 g of rhizoma anemarrhenae with alcohol or water or refining honey to prepare paste, and preparing the paste into a required dosage form. The traditional Chinese medicine composition has the beneficial effects that after scientific and reasonable compatibility and preparation, the medicine effect has a synergistic effect, and the traditional Chinese medicine composition has the effects of nourishing yin, clearing heat, calming the heart and soothing the nerves and is used for treating insomnia caused by fire excess from yin deficiency and liver depression.

The invention discloses an application of a pyrrosia lingua aqueous extract in preparation of a medicine for preventing and treating radioactive intestinal injury. Radioactive intestinal injury is a common complication of ionizing radiation, and has main pathological characteristics of intestinal mucosal barrier destruction, excessive release of inflammatory factors, increase of oxidative stress level and hematopoiesis and immune function inhibition. At present, no effective and safe prevention and treatment medicine is available. It is found for the first time that the pyrrosia lingua aqueous extract can inhibit expression (IL-6, TNF-alpha and IL-1beta) of inflammatory factors of radiation-induced MODE-K cells and relieve the oxidative stress level (malondialdehyde (MDA) is reduced, and the content of superoxide dismutase (SOD) and glutathione (GSH) is increased). In animal experiments, the pyrrosia lingua aqueous extract can reduce the levels of TNF-alpha and IL-1beta inflammatory factors in serum of irradiated mice and improve oxidative stress disorders such as MDA increase, SOD and GSH decrease and the like; the reduction of leukocytes and lymphocytes is relieved; the length of intestinal villus is promoted and recovered; the proportion of Ki67 positive cells in a crypt region is increased, so that the regeneration capacity of intestinal epithelial cells is enhanced. The pyrrosia lingua aqueous extract disclosed by the invention provides an experimental basis and an application prospect for developing a novel medicine for preventing and treating the radioactive intestinal injury.

The invention provides a process for removing cyanide from a cyanide-bearing aqueous fluid, the process comprising: (i) adding a solid composition comprising a first mixed-metal cyanide complex comprising copper and iron to a cyanide-bearing aqueous fluid comprising free cyanide and metal-complexed cyanide, wherein at least a portion of the first mixed-metal cyanide complex dissolves, with complexation of the copper by the free cyanide, to produce an aqueous solution comprising cyanometallates, the cyanometallates comprising copper cyanide and iron cyanide complexes derived from the first mixed-metal cyanide complex; (ii) contacting the aqueous solution with an anion-exchange absorbent to absorb the cyanometallates, thereby producing a cyanide-lean aqueous fluid; (iii) extracting the anion-exchange absorbent comprising the absorbed cyanometallates with at least one non-acidic aqueous extractant to produce an aqueous extract comprising the copper cyanide and iron cyanide complexes; and (iv) acidifying the aqueous extract to produce a precipitate comprising a second mixed-metal cyanide complex comprising copper and iron.

The invention belongs to the technical field of seedling culture. The invention provides a special nutrient solution for floating seedling raising of tobacco. The nutrient solution comprises the following components: 1000g of water, 0.3-0.5 g of acorus calamus and goldhair hedyotis herb aqueous extract fermented product, 0.1-0.3 part of corn straw steam explosion enzymolysis fermented product, 0.2-0.4 g of calcium ammonium nitrate, 0.6-0.8 g of potassium sulfate, 0.3-0.5 g of ammonium bicarbonate, 0.3-0.5 part of ammonium dihydrogen phosphate, 1-2mg of boric acid and 1-2mg of zinc sulfate. The nutrient solution special for tobacco floating seedling raising can remarkably improve the emergence rate of floating seedling raising, improve the seedling strengthening index and greatly reduce the disease index of tobacco infected with black shank; when the special nutrient solution for tobacco floating seedling raising is prepared, the used technical treatment means are mature technologies in the industry, so that the special nutrient solution has higher feasibility and high industrial application value.

A method for treating a gastrointestinal condition includes preparing an aqueous extract of bioactive compound by adding dried green tea material to hot water and filtering the aqueous extract; adding a solution of an iron-containing compound to the filtered aqueous extract to form a complex or chelate of the bioactive compounds with iron; and drying the solution at a temperature between 80 to 150 degrees Fahrenheit to obtain a fine granular or powdered state.

The invention discloses a polygala tenuifolia aqueous extract as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) removing impurities from a polygala tenuifolia medicinal material, and crushing to obtain polygala tenuifolia coarse powder for later use; (2) putting the polygala tenuifolia coarse powder obtained in the step (1) and pure water into an extraction device according to a solid-liquid ratio of 1: (10-15) (g / mL), and extracting for 2-3 times while keeping a slight boiling state; (3) after each time of extraction in the step (2) is finished, filtering, and collecting filtrate of each time to obtain a polygala tenuifolia water extract; and (4) concentrating and drying the polygala tenuifolia water extract in the step (3) to obtain polygala tenuifolia water extract dry powder. The polygala tenuifolia aqueous extract is used as an effective component to prepare the external medicament for treating the red and swollen skin, so that the limitation of dosage forms such as original water decoction or medicine residue external application is broken through, the transdermal absorption and the curative effect are remarkably improved, the efficient local treatment of the skin abscess is realized, and the problems of systemic side effects and drug resistance of antibiotics caused by oral medicines are avoided; the applicable crowd is expanded.

The invention provides a semen ziziphi spinosae and poria cocos composition. The composition comprises semen ziziphi spinosae extract, poria cocos extract and gamma-aminobutyric acid, wherein the semen ziziphi spinosae extract is formed by combining semen ziziphi spinosae whole powder, semen ziziphi spinosae aqueous extract and semen ziziphi spinosae, and the poria cocos extract is formed by poria cocos powder and poria cocos aqueous extract. The invention also provides a preparation comprising the composition, and a food product comprising the composition or the preparation. The invention further provides application of the composition or the preparation in preparation of health care products or medicines. The composition provided by the invention is prepared by compatibility of pure natural components according to the theory of traditional Chinese medicine, can effectively prolong the sleep time of pentobarbital sodium and remarkably shorten the sleep latency of mice under the condition of not influencing direct sleep of the mice, and has a certain improvement effect on the sleep of the mice. The composition and the preparation provided by the invention have a remarkable improvement effect on sleep-related symptoms, and have important market value and development prospect.

The invention relates to a method for extracting at least one target extract from at least one plant and / or at least one fungus, comprising at least the following steps: (a) providing at least one plant and / or at least one fungus; (b) subjecting the plants and / or fungi to at least one extraction cycle comprising: (b1) at least one first microwave-assisted extraction step, thereby obtaining a first aqueous extract; and (b2) carrying out at least one second impregnation step on the first aqueous extract obtained in step (b1), thereby obtaining the target extract, and wherein steps (b1) and (b2) are carried out by water naturally present in plants and / or fungi without the addition of an extraction solvent.

The invention belongs to the field of respiratory system disease treatment, and provides application of a gymnadenia conopsea extract in preparation of a medicine for treating or preventing pulmonary edema. The embodiment of the invention proves that both the gymnadenia conopsea alcohol extract and the gymnadenia conopsea water extract can effectively improve indexes such as pulmonary edema respiratory rate, minute ventilation volume, rising tidal volume, inspiration peak flow, expiration peak flow and the like, and improve arterial blood-gas indexes and inflammatory factor level in alveolar lavage fluid. The invention provides the application of the gymnadenia conopsea alcohol extract and the gymnadenia conopsea water extract in the medicine for treating or preventing lung diseases, especially pulmonary edema for the first time, the traditional medicine gymnadenia conopsea is fully developed and utilized, and a safe and effective means is provided for treating the critical disease pulmonary edema.

The disclosure relates to a continuous process for obtaining phosphoric acid and calcium sulphate dihydrate from apatite, and sulphuric acid using hydrochloric acid as an intermediate attacking agent, comprising the steps: Leaching (101) apatite (11) with an aqueous solution of hydrochloric acid (12,13) to solubilize phosphorus compounds contained in the apatite, thereby obtaining a solution (15) containing phosphate (H3PO4) and calcium chloride (CaCl2); extracting (103) said solution (15) with organic solvent (16), yielding an organic extract (17) loaded with phosphate ions, and an aqueous raffinate (21) containing calcium chloride and residual impurities; re-extracting the phosphate ions from the organic extract (17) with water (18), thus yielding an aqueous extract (19) of phosphoric acid, and an unloaded organic phase substantially free of phosphoric acid, reacting (107) the raffinate (21) containing calcium chloride with sulphuric acid (26) to cause precipitation of calcium ions in the raffinate as calcium sulphate dihydrate and to recover chloride ions in the raffinate in the form of hydrochloric acid (12), wherein the reaction of the raffinate (21) containing calcium chloride with sulphuric acid (26) involves intermittent agitation of the raffinate, filtering off (108) precipitated calcium sulphate dihydrate (27) from the previous step (107) and washing it with water, recycling (112) the recovered hydrochloric acid (12) to the step (101) of the leaching apatite.

The invention relates to a male anti-ED composition containing a burdock root aqueous extract and a preparation method of the male anti-ED composition, and relates to the technical field of male anti-ED composition preparation. The composition comprises a burdock root aqueous extract, ginsenoside and puerarin, and the mass ratio of the burdock root aqueous extract to the ginsenoside to the puerarin is (5-8): (0.5-1): (0.2-0.5). The invention provides an anti-ED composition taking a burdock root aqueous extract, ginsenoside and puerarin as synergistic active components and a preparation method thereof. The curative effect is improved through a multi-target synergistic effect of ternary combination.

The invention discloses plant lactobacillus BT810 and application thereof in preparing rare ginsenoside by fermenting ginseng flower buds, and belongs to the field of fermentation engineering. The lactobacillus plantarum BT810 is preserved in the China Center for Type Culture Collection on August 18, 2025, and the preservation number of the lactobacillus plantarum BT810 is CCTCC (China Center for Type Culture Collection) NO: M20251845. According to the method, a ginseng flower bud aqueous extract is taken as a fermentation substrate and inoculated with phytobacterium plantarum BT810 for standing fermentation, and ginsenoside Re in the ginseng flower bud aqueous extract is selectively hydrolyzed by beta-glucosidase secreted by the BT810 and is directionally converted into Rg2 and Rg4. The method has the advantages of extremely low by-products, high conversion rate, mild reaction conditions, low preparation cost and easiness in expanded production, and a convenient way is provided for large-scale, low-cost and efficient co-preparation of the rare ginsenosides Rg2 and Rg4.

The application discloses a sunscreen composition based on the ultraviolet absorption characteristics of yellow water of liquor, and a preparation method and application thereof. The sunscreen composition comprises 10-60 parts by weight of a yellow water extract of a strong-flavor liquor, 20-70 parts by weight of a yellow water extract of a Maotai-flavor liquor, and 0-40 parts by weight of a yellow water extract of a light-flavor liquor. It is found that the yellow water of different flavor liquors has characteristic ultraviolet absorption spectrum, wherein the yellow water of the strong-flavor liquor has strong absorption in the UVB band (290-320 nm), the yellow water of the Maotai-flavor liquor has strong absorption in the UVA band (340-380 nm), and the yellow water of the light-flavor liquor has relatively uniform absorption in a wide band. According to the spectral complementarity, the natural sunscreen composition is obtained. The sunscreen composition has an in-vitro SPF value of 15-35, a PA value of ++~++++, good light stability and low skin irritation.

This invention discloses a Tibetan medicine formula called Mabosongtang Lung-Nourishing Composition and its preparation method and application in modern formulations, more specifically relating to a preparation method and application of Mabosongtang Lung-Nourishing granules, oral liquid, and capsules. The composition is mainly prepared from the following medicinal materials: Tibetan Lithospermum erythrorhizon, Tibetan Rubia cordifolia, Lithospermum erythrorhizon, Bambusa textilis, Morinda officinalis, Lysimachia christinae, Hippophae rhamnoides, and Glycyrrhiza uralensis. The aqueous extract of this composition, with appropriate excipients, is prepared into granules, oral liquid, and capsules using modern pharmaceutical processes. The three formulations are effective, rationally formulated, advanced in dosage form, and stable in quality. They have the effects of calming the lungs, suppressing blood stasis, and clearing lung heat. They can be used for respiratory symptoms caused by the invasion of pathogenic factors into the lungs, and dysfunction of the lung's vital energy and ascending qi, such as cough, wheezing, shortness of breath, etc. (treatment of lung diseases with the above symptoms).

The invention belongs to the field of biological medicines, and particularly relates to a ganoderma lucidum spore powder extract for treating acute lung injury by regulating intestinal flora and application thereof. The preparation method of the ganoderma lucidum spore powder extract (aqueous extract) comprises the following steps: selecting wall-broken ganoderma lucidum spore powder as a raw material, adding ultrapure water into the wall-broken ganoderma lucidum spore powder according to a solid-liquid ratio of 1g / (9-11) mL, firstly performing ultrasonic oscillation dissolution, then performing constant-temperature extraction, and then performing centrifugation to take supernate as a ganoderma lucidum spore powder extract solution. The invention also provides application of the ganoderma lucidum spore powder extract in preparation of medicines for regulating intestinal flora and treating acute lung injury.

This invention relates to a method for obtaining aqueous extracts of tea leaves (Camellia sinensis), particularly fresh tea leaves, Pu-erh tea, matcha, or green tea. The invention also relates to tea extracts rich in small RNAs, sugars, phenolic compounds, organic acids, catechins, and theanine, as well as cosmetic compositions comprising such extracts and their cosmetic uses for the care of the skin, scalp, and appendages, particularly for protecting the skin from external aggressors and oxidation, combating signs of skin aging, enhancing photoprotection, brightening the skin, and improving skin hydration.

The invention provides aroma-enhancing highland barley wine and a preparation method thereof. The method comprises the following steps: step 1, pretreating raw materials to obtain a highland barley aqueous extract; step 2, primary fermentation: inoculating a bacillus subtilis bacterial solution, and carrying out stepped temperature fermentation to obtain a primary fermentation solution; step 3, secondary fermentation: adjusting the pH value and the sugar degree, and carrying out segmented inoculated fermentation: at the first stage, inoculating lactobacillus plantarum; a second stage: inoculating sweet distiller's yeast and saccharomycetes to obtain secondary fermentation liquor; and step 4, canning and sterilizing. According to the method disclosed by the invention, by virtue of a stepped temperature control, sodium citrate directional induction and pH shift triple regulation and control method, a burdens link of generating peculiar smell and needing subsequent treatment in the primary fermentation process of the bacillus subtilis is thoroughly converted into a dominant link of actively generating a high-quality flavor precursor, and a final product has a high score of 93.5 in sensory evaluation; the highland barley fermented wine is pure and harmonious in fragrance and mellow and refreshing in taste, has a typical highland barley fermented wine style and does not have any foreign flavor.

The present invention generally relates to the use of a sweetening composition comprising (i) a mycelia of an ascomycete or an aqueous extract thereof or (ii) an aqueous extract of a fruiting body of an ascomycete, to provide improved flavor to a product for oral administration, as well as to a sweetening composition comprising (i) a mycelia of an ascomycete or an aqueous extract thereof or (ii) an aqueous extract of a fruiting body of an ascomycete as well as to compositions comprising combinations of sweetening compositions and a product for oral administration.

The invention discloses prebiotics-enriched kombucha fermented castanopsis sclerophylla jelly which comprises the following components in parts by mass: 40-70 parts of castanopsis sclerophylla fermentation liquor, 3-15 parts of isomaltooligosacharide, 1-16 parts of purple sweet potato anthocyanin water extract, 6-22 parts of a composite coagulator and the balance of water. The invention also discloses a preparation method of the composition. Bitter taste of the castanopsis sclerophylla is reduced through kombucha fermentation, and flavor of the castanopsis sclerophylla is enriched; prebiotics (purple sweet potato anthocyanin and isomaltooligosacharide) are added for color mixing and seasoning, so that the sensory quality of the castanopsis sclerophylla jelly is enhanced, and meanwhile, the health effect of the castanopsis sclerophylla jelly is enhanced; by preparing the low-temperature composite coagulator, heating is not needed, the activity of probiotics in the jelly is kept to the maximum extent, and the effect of improving intestinal health is further enhanced. The fermented castanopsis sclerophylla jelly product with both prebiotics and probiotics is prepared by the method disclosed by the invention. Technical support is provided for development of high-added-value castanopsis sclerophylla food.

A method of increasing skin firmness or elasticity of a person's skin is disclosed. The method can include topically applying a composition comprising an effective amount of a water extract of Cucurbita pepo (pumpkin) seed to skin in need thereof, wherein the water is a marine spring water and the Cucurbita pepo (pumpkin) seed extract comprises an amino acid from the Cucurbita pepo (pumpkin) seed, and wherein topical application of the composition increases skin firmness or elasticity of the person's skin.

The present invention provides compositions comprising extracts from green algae to prevent microbial infestation, including the reduction of mold and fungal growth on plants or post-harvest fruits and vegetables. The present invention further provides compositions comprising environmentally safe aqueous extracts of Ulva Lactuca as antifungal agents that may be used in various forms including in conjunction with coatings for postharvest produce in order to prolong shelf-life, prevent shrinkage and preserve the appearance and gloss of fruits and vegetables.

The invention discloses a novel ginseng stem cell culture system which comprises a basic culture medium and a growth regulation composition, and the basic culture medium comprises ammonium sulfate, monopotassium phosphate, magnesium sulfate heptahydrate and calcium chloride; the growth regulating composition comprises 2, 4-dichlorphenoxyacetic acid, zeatin, salicylic acid and natural polysaccharide. The basic culture medium also comprises casein hydrolysate, coconut water extract and cane sugar. The composition also comprises an anti-oxidation composition. The invention further discloses a disposable flexible bioreactor for ginseng stem cell culture, the bioreactor comprises a tank body made of a flexible material, an air distribution device, a sterile sampling device and an online parameter monitoring device, and the top of the tank body structure is a cylindrical body and is provided with an inoculation opening, a culture medium liquid supplementing opening, an air outlet and a sampling opening; the bottom is an inverted cone provided with a parameter monitoring device interface and an air inlet, and the air inlet is connected with a ventilation device and an air flow adjusting device. The invention also discloses application of the culture system and the bioreactor.

The invention relates to the technical field of traditional Chinese medicine detection, in particular to a method for identifying the production place and aging year of pericarpium citri reticulatae, which comprises the following steps: acquiring a pericarpium citri reticulatae powder sample, detecting characteristic elements by adopting a portable X-ray fluorescence spectrophotometer, inputting the characteristic elements into a production place prediction model, and identifying whether the pericarpium citri reticulatae is the production place of a new meeting area or not; adding ultrapure water into the powder sample of which the characteristic elements are detected, carrying out ultrasonic extraction, centrifuging, and taking supernate, so as to obtain a pericarpium citri reticulatae water extract; and measuring the pH value, the conductivity and the 420nm light absorption value of the dried orange peel water extract, and inputting into the year function model to identify the aging year of the dried orange peel sample. According to the method, through a mode of optimizing a sample treatment flow and integrating multiple models, one sample and one-time pretreatment are realized, and double-index identification of the production place and the aging year is synchronously completed. While the detection accuracy is ensured, the detection time is greatly shortened, the sample consumption and the operation complexity are reduced, and the requirements of on-site rapid detection and large-scale production area and year monitoring are met.

To reveal the health benefits of Ecklonia kurome and to provide compositions that can be used in foods and the like.SOLUTION: Provided is a composition for lipase activity inhibition, lipid absorption inhibition, stool slippage improvement, or intestinal regulation, which contains an effective amount of the water extract of Ecklonia kurome. Provided is a method for producing the water extract or processed product of Ecklonia kurome, including the following step: (1) extracting Ecklonia kurome with hot water at 50-80°C for 1-5 hours.SELECTED DRAWING: Figure 1

Composition comprising a biochar and an aqueous extract of a seed legume. The present invention relates to a composition comprising a biochar and an aqueous extract of a seed legume, a method for preparing said composition and the use of the composition to promote seed germination, to improve the nutrient utilization efficiency of a seed, to promote seedling development and to improve seedling tolerance to abiotic stress.

The invention relates to the technical field of skin care, and discloses a sustained-release composition containing azelaic acid composite lipidosome and application of the sustained-release composition in acne treatment and skin repair. Comprising a composite liposome, an encapsulated active component and a dispersion medium, the composite liposome is composed of a lipid bilayer, the lipid bilayer comprises phospholipid, cholesterol and pegylated phospholipid, and the phospholipid is a mixture of hydrogenated soybean phospholipid and dipalmitoyl phosphatidylcholine; the encapsulated active component comprises a fat-soluble component and a water-soluble component; the water-soluble components comprise a hamamelis virginiana leaf water extract and a herba portulacae extract; the dispersion medium is a phosphate buffer solution; by optimizing lipid composition, introducing surface modification and constructing a multi-layer release system, the invention aims to synergistically exert multiple effects of antibiosis, anti-inflammation, cutin regulation, red fading, repair and the like, and provides an efficient, mild and integrated solution for acne and sequelae skin problems thereof.