311 results about "Konjac glucomannan" patented technology

The invention discloses a method for preparing low-GI rice noodles from a white kidney bean-mulberry leaf composite extract, which comprises the following steps of: firstly, extracting functional components in white kidney beans and mulberry leaves by adopting a water extraction method, adding Arabic gum and resistant dextrin into a white kidney bean-mulberry leaf composite extracting solution, regulating acid, and performing glycosylation and embedding treatment; uniformly mixing rice flour, high amylose, fiber powder, konjac glucomannan, mono-glycerol fatty acid ester, diglycerol fatty acid ester and the white kidney bean-mulberry leaf compound extracting solution; and finally, humidifying, cooking, extruding and forming to obtain the low-GI rice noodles. According to the invention, the glucogenic index of the rice noodles is reduced by adding the white kidney bean-mulberry leaf composite extract, the heat resistance of functional components in the composite extract is improved through glycosylation and embedding treatment, and the loss of the activity of the white kidney bean-mulberry leaf composite extract in the high-temperature cooking process of the rice noodles is reduced; meanwhile, in order to improve the flavor and taste of the low-GI rice noodles, the konjac glucomannan and other auxiliary materials are added, so that the low-GI rice noodles are rich in elasticity and better in taste and boiling fastness.

The invention relates to the technical field of flocculants, in particular to a composite flocculant containing a cationic etherifying agent and a preparation method of the composite flocculant, and the composite flocculant is prepared from the following raw materials in parts by weight: 15-20 parts of carboxymethyl guar gum, 12-15 parts of cationic konjac glucomannan, 1.2-1.5 parts of the cationic etherifying agent, 1.8-2.2 parts of a magnetic polysilicate metal salt flocculant and 0.2-0.3 part of a preservative. According to the present invention, by compounding the flocculant, the flocculated floc has magnetism and can be recovered and repeatedly utilized, and the photoresponse azobenzene structure is grafted in the cationic konjac glucomannan, such that the controllable pollutant aggregation and separation can be achieved, and the good flocculation performance can be maintained after the composite flocculant is repeatedly recovered and repeatedly utilized.

The invention discloses multifunctional hydrogel for promoting healing of diabetic wounds and a preparation method of the multifunctional hydrogel. The multifunctional hydrogel is prepared from Ti3C2Tx-Ag, paeoniflorin (PF), a gel matrix oxidized konjac glucomannan (OKGM) solution and carboxymethyl chitosan (CMCS). The method comprises the following steps: mixing Ti3C2Tx powder with AgNO3 in deionized water, heating to boiling, adding a proper amount of a sodium citrate solution, reacting to obtain Ti3C2Tx-Ag (TA) powder, and mixing the powder with a paeoniflorin (PF) and oxidized konjac glucomannan (OKGM) solution and a carboxymethyl chitosan (CMCS) solution to prepare the KC-PF-TA hydrogel. The multifunctional hydrogel has excellent photo-thermal antibacterial performance, anti-inflammatory performance and angiogenesis promoting performance, shows a remarkable effect of promoting healing of diabetic wounds through the synergistic effect of Ti3C2Tx-Ag and paeoniflorin, and has good biocompatibility; the multifunctional nano-composite hydrogel disclosed by the invention has great application prospect and value in the field of wound repair materials.

The preparation method comprises the following steps: S1, raw material preparation: selecting sodium selenite as a selenium source, and preparing konjac glucomannan and vitamin C as reducing agents at the same time; the molar ratio of the selected sodium selenite to the selected konjac glucomannan to the selected vitamin C is 1: (0.5-2): (2-5); s2, solution preparation: dissolving sodium selenite in deionized water to prepare a sodium selenite solution with the concentration of 0.1-0.5 mol / L; according to the preparation method of the nano-selenium fertilizer, through the nano-selenium fertilizer prepared through the steps S1 to S6, the particle size of nano-selenium particles can be distributed between 30 nm and 80 nm, so that the nano-selenium fertilizer has good dispersity and stability and is conveniently and efficiently applied to agricultural production, and the effect of improving the selenium absorption and utilization efficiency of crops is achieved; and the preparation method is simple and easy to implement, low in cost, green and environmentally friendly.

The invention discloses a natural eutectic solvent enhanced konjac glucomannan film as well as a preparation method and application thereof, and belongs to the technical field of food packaging. The konjac glucomannan film enhanced by the natural deep eutectic solvent, provided by the invention, comprises konjac glucomannan, the natural deep eutectic solvent and gallic acid modified MXene nanoparticles; the mass ratio of the konjac glucomannan to the natural eutectic solvent to the gallic acid modified MXene nanoparticles is (850 to 950) to (50 to 250) to (10 to 40). Through the synergistic effect of all the components, the defects that KGM is insufficient in intrinsic mechanical strength, weak in antibacterial and antioxidant performance and poor in moisture resistance are overcome, the comprehensive performance of the film is remarkably improved, and the film can be used for cold-chain packaging of high-value fresh food and has environment friendliness and functional practicability.

The invention discloses a flocculating agent for coking wastewater and a preparation method and application thereof, the flocculating agent is prepared from the following raw materials in parts by weight: 1-5 parts of poly dimethyl diallyl ammonium chloride and 6-12 parts of a compound, and the compound is prepared from kaolin loaded N-succinyl-O-carboxymethyl chitosan and konjac glucomannan. The method is used for solving the technical problem that the coking wastewater cannot reach the discharge standard.

The invention discloses a preparation method of a konjac glucomannan-based hydrophobic biomass film. The method comprises the following steps: S1, purification: eluting konjac powder, drying, grinding and screening to obtain konjac glucomannan; s2, modification: fully stirring and mixing the purified konjac glucomannan with an ethanol solution to prepare a homogeneous solution, adding a sodium hydroxide solution, and carrying out a deacetylation reaction to obtain deacetylated konjac glucomannan; s3, preparing a film: blending the deacetylated konjac glucomannan with agar, pullulan and glycerol in a solvent, heating and stirring to form a film solution, defoaming and drying to obtain a konjac glucomannan-based hydrophobic biomass film formed by the deacetylated konjac glucomannan, the agar and the pullulan; the konjac glucomannan-based hydrophobic biomass film prepared by the method has good hydrophobic performance, mechanical performance and the like, is beneficial to reducing the dependence on fossil energy, promotes the development of circular economy, and makes a contribution to environmental protection and sustainable development.

The invention relates to the technical field of thickening agents, in particular to a thickening agent for fracturing fluid and a preparation method of the thickening agent, the thickening agent comprises a liquid material and a solid material, the mass ratio of the liquid material to the solid material is 1: (2.2-2.4), and the liquid material is composed of deionized water and N-methyl pyrrolidone. According to the preparation method disclosed by the invention, the konjaku flour is added in the preparation of the thickening agent, and after the konjaku flour is subjected to mixing reaction and curing treatment, amino functional groups in konjaku molecules can be subjected to cross-linking reaction with aldehyde groups of glutaraldehyde, so that water molecules are wrapped in a cross-linked network structure, and the internal friction force during fluid flowing is increased; and hydroxyl groups on molecular chains of the konjac glucomannan and aldehyde groups of glutaraldehyde are subjected to a condensation reaction to form covalent bonds, so that a cross-linking effect is achieved, a stable chemical cross-linked network structure is formed among the molecular chains of the konjac glucomannan, and the cross-linking performance of the thickening agent is effectively improved.

The invention relates to the technical field of plastic bags, in particular to an antibacterial degradable plastic bag and a preparation method thereof. The antibacterial degradable plastic bag is prepared from the following raw materials in parts by weight: 60-80 parts of polyhydroxyalkanoate, 30-40 parts of filler, 2-4 parts of an antioxidant and 0.6-1 part of an active agent. In the preparation process of the antibacterial degradable plastic bag, in a filler system, vesuvianite powder and eggshell powder are used as inorganic reinforcing phases, sericin and mulberry leaf powder are used as bioactive phases, flax and cotton provide a natural fiber structure, and lignin and konjac glucomannan are used as bio-based bonding materials; and the eggshell powder is compact in crystal structure after being subjected to high-temperature calcination treatment, and can be used as a stress transfer medium in a material system, so that the stress concentration when the plastic bag is stressed is reduced, and the strength performance of the plastic bag is improved.

The invention provides an intelligent antibacterial konjac glucomannan composite film and a preparation method thereof. The intelligent antibacterial konjac glucomannan composite film is prepared by carrying out graft copolymerization on oxidized konjac glucomannan OKGM and amino-functionalized poly (N-isopropylacrylamide) PNIPAM-NH2 and then crosslinking with an antibacterial agent, the tail end of a molecular chain of the amino-functionalized poly (N-isopropylacrylamide) is provided with an amino group. The intelligent antibacterial konjac glucomannan composite film disclosed by the invention has temperature responsiveness, can control the release of an antibacterial agent according to environmental changes, ensures that the antibacterial agent is accurately released as required, and effectively prolongs the food preservation time and the food shelf life. The film is good in biocompatibility, has no obvious toxic reaction on human tissues and cells, and provides possibility for application in the field of biomedicine. Besides, the film has degradability, and the OKGM and the chitosan are natural high polymer materials and can be decomposed into harmless substances by microorganisms in the natural environment, so that the film meets the requirements of environmental protection and is beneficial to reducing environmental pollution.

The invention belongs to the technical field of phase change energy storage materials, and particularly relates to thermally driven memory flexible phase change hydrogel and a preparation method thereof. Comprising the following steps: taking konjac glucomannan as a raw material, taking an inorganic phase-change material as a solvent, and enabling the inorganic phase-change material to enter a hydrogel network to obtain a hydrogel solution; sequentially adding acrylamide, a cross-linking agent and hydrothermal carbon into the hydrogel solution, and uniformly mixing to obtain a phase change hydrogel precursor; and adding an initiator into the phase change hydrogel precursor, and carrying out polymerization reaction to obtain the thermally driven memory flexible phase change hydrogel. The phase change hydrogel with shape memory behavior and high photo-thermal conversion capability is prepared, the problem of high-temperature leakage of sodium sulfate decahydrate can be effectively solved, the sodium sulfate decahydrate packaging efficiency is improved to 90.4 wt%, meanwhile, hydrothermal carbon forms a continuous and effective photo-thermal conversion and heat conduction path under the help of a three-dimensional network of the hydrogel, and the heat conduction efficiency of the sodium sulfate decahydrate is improved. The phase change hydrogel shows excellent photothermal conversion performance and heat conductivity coefficient.

The invention relates to a preparation method and application of a corn straw beverage, belongs to the technical field of plant resource processing, and solves the technical problem of activity loss caused by easy oxidative degradation of flavonoid compounds in a corn straw water extract. According to the technical scheme, the method comprises the following steps: crushing corn straws, soaking in water, performing heat extraction for multiple times to obtain an extracting solution, performing rough filtration and centrifugation, and concentrating to obtain a water extracting solution; and mixing the water extract, sucralose, citric acid, potassium sorbate and purified water to prepare a beverage, sterilizing and filling. Flavonoid compounds are embedded through a potato starch nanoparticle and beta-cyclodextrin composite carrier, a sodium alginate-chitosan microcapsule double-layer coating and microcapsule jelly particle preparation technology is combined, a gel network is formed by compounding kappa-carrageenan and konjac glucomannan, and the embedding stability and release controllability of active ingredients are improved. The beverage prepared by the method has both herbal flavor and crisp and tender taste of jelly particles, effectively delays degradation of flavonoid compounds, and is suitable for being applied to development of functional plant beverages.

The invention relates to the technical field of biological medicine materials, and provides a preparation method and application of biological polysaccharide macromolecule polymerization coated PQQ, a polysaccharide macromolecule slow-release skeleton carrier used for coating in the method comprises konjac glucomannan and chitosan, the carrier can form a honeycomb net structure, PQQ can be embedded into the net structure, and the PQQ can be embedded into the honeycomb net structure. The coated PQQ has a slow release function in the intestinal environment, the three-dimensional honeycomb structure can be extended under the intestinal environment condition, the PQQ is slowly released, and more than 90% of the PQQ is released within 8 hours.

The invention relates to the technical field of flocculants, and in particular to a composite flocculant containing a cationic etherifying agent and a preparation method thereof. The composite flocculant comprises the following raw materials in parts by weight: 15-20 parts of carboxymethyl guar gum, 12-15 parts of cationic konjac glucomannan, 1.2-1.5 parts of cationic etherifying agent, 1.8-2.2 parts of magnetic polysilicate metal salt flocculant, and 0.2-0.3 parts of preservative. By compounding the flocculant, the flocculated flocs have magnetism and can be recycled and reused. Furthermore, since a photoresponsive azobenzene structure is grafted into the cationic konjac glucomannan, controllable pollutant aggregation and separation are achieved, ensuring that the composite flocculant can maintain good flocculation performance after multiple recycling and reuse.

The invention discloses a method for preparing a freeze-thaw resistant prefabricated semi-proofed Chinese frozen dough. The frozen dough of the invention is made of the following raw materials in parts by weight: 1-2 parts of active dry yeast, 1-2 parts of pre-treated fish bone, fish scale and shrimp shell enzymatic hydrolysis mixture, 100 parts of all-purpose flour, 0.025-0.075 parts of ice structure protein, 0.025-0.075 parts of konjac glucomannan, and 48-50 parts of purified water; the above raw materials are mixed and pre-treated, kneaded to form dough, proofed once, vented, cut and shaped, and frozen to obtain the dough. The method of the invention is simple, low in cost, and flexibly applicable to Chinese pastries with different production requirements, and effectively solves the quality problems of shrinkage, cracks, discoloration, low yeast activity, and poor taste after repeated freezing and thawing. It can be used to make Chinese fermented foods such as steamed buns, flower rolls, and dumplings, and can also supplement the lack of some amino acids, oils, trace elements, and functional ingredients in pastry products and enhance the flavor.

The invention belongs to the technical field of food processing, and particularly relates to a sleep-aiding composition, a sleep-aiding aqueous extract and a preparation method and application of the sleep-aiding composition and the sleep-aiding aqueous extract. The invention provides a sleep-aiding composition. The sleep-aiding composition is prepared from the following components in parts by mass: 67.5 to 157.5 parts of semen ziziphi spinosae, 67.5 to 157.5 parts of Zanghuang jujubes, 0.3 to 0.7 part of konjac glucomannan, 10 parts of poria cocos and 6 parts of liquorice roots. All the components in the sleep-aiding composition are medicinal and edible medicinal materials, and food is used for treatment, so that the product has small toxic and side effects; meanwhile, the Zanghuang jujubes are added to be compounded with the spina date seeds, so that the obtained composition not only has rich red date fragrance and strong date flavor, but also can improve the content of sleep-aiding active substances, and has the effects of soothing the nerves and aiding sleep.

The invention discloses a microbial odor remover suitable for environment and a preparation method thereof, and relates to the technical field of daily chemical products. The preparation method comprises the following steps: adding pediococcus acidilactici and bacillus velezensis into a citric acid-disodium hydrogen phosphate buffer solution according to a ratio, standing and activating, adding bromelain, lipase, rosmarinic acid nanoemulsion, tea polyphenol and citrus polyphenol-EDTA (Ethylene Diamine Tetraacetic Acid) mixture, homogenizing, adding konjac glucomannan-chitosan gel and a trehalose-glycerol compound according to a ratio, stirring, filtering, and drying to obtain a finished product. And subpackaging in a dark place to prepare the microbial odor remover suitable for the environment. Through the synergistic effect of microorganisms, enzymes and a natural deodorization medium, a multi-stage peculiar smell elimination system is constructed, the dual functions of immediate neutralization and continuous bacteriostasis are achieved, the application scene is wide, corrosion and residues to base materials such as fabric and plastic are avoided, and the concentration of harmful gas can be more effectively controlled and pathogenic microorganisms can be inhibited in large-scale breeding application.

The invention relates to the field of food seasonings, and discloses salad dressing containing dietary fibers and a preparation method of the salad dressing. The invention discloses salad dressing containing dietary fibers. The salad dressing is prepared from the following raw materials in parts by weight: 15-25 parts of egg white, 10-20 parts of yolk, 5-10 parts of vegetable oil, 18-24 parts of dietary fibers, 3-5 parts of a thickening agent, 2-4 parts of a sweetening agent, 3-5 parts of a flavoring agent, 0.03-0.06 part of a preservative and 30-40 parts of water. The dietary fiber consists of oat, konjac glucomannan and oligosaccharide in a weight ratio of (22-25): (1-2): (4.5-5.5); the preparation method comprises the following steps: whipping the egg white and the sweetening agent to prepare egg white cream; emulsifying egg yolk and vegetable oil to obtain an emulsion; preparing a mixture from the thickening agent, the flavoring agent, the preservative and the water; and emulsifying the emulsion, the protein cream, the dietary fibers and the mixture. The salad dressing prepared by the invention has relatively good taste and texture and good water-retaining property, and is not easy to layer and precipitate after being stored for a long time.

The invention belongs to the field of food processing, and provides a pepper and sesame flavor chicken sauce and a preparation method thereof; flavor protease and trypsin are added to the squeezed pepper pulp, and the pepper emulsion is obtained by enzymolysis and homogenization, and papain and lipase are added to the chicken at the same time, and ginger, cooking wine, white sugar and other seasonings are added after enzymolysis, and chicken sauce is obtained after high-pressure stewing, and the chicken sauce, the pepper emulsion and konjac glucomannan are mixed and prepared to obtain the pepper and sesame flavor chicken sauce. Compared with the prior art, the bitterness of the pepper and sesame flavor chicken sauce is reduced, and the texture of the product is more stable.

The invention provides a feed premix for improving chicken quality. The fresh-keeping agent is prepared from the following components in percentage by weight: 5%-15% of a flavor enhancing component, 10%-25% of a tenderness improving component, 3%-10% of an antioxidant fresh-keeping component, 2%-3% of a function enhancing component and the balance of a carrier and a diluent, the function strengthening component is prepared from beta-alanine embedded citronella essential oil and konjac glucomannan zymolyte; the flavor enhancing component comprises a rosemary extract, a yeast culture and curcumin in a mass ratio of (2-4): (1-3): 1; the tenderness improving component comprises conjugated linoleic acid, L-carnitine modified by glutamine transaminase and betaine in a mass ratio of (3-5): (2-4): 1; the antioxidant fresh-keeping component is vitamin E and tea polyphenol in a mass ratio of (1-2): 1. Through multi-component synergism and functional targeting optimization, a three-dimensional quality improvement system with enhanced flavor, improved tenderness, oxidation resistance and fresh keeping is constructed, so that the chicken quality is comprehensively upgraded.

The invention provides a dietary fiber composition for reducing weight and regulating intestinal flora in a targeted manner as well as a preparation method and application of the dietary fiber composition. The composition is prepared from the following raw materials in parts by weight: 20 to 30 parts of inulin, 15 to 25 parts of germinated brown rice powder, 10 to 20 parts of pectin, 8 to 15 parts of guar gum, 12 to 20 parts of beta-glucan, 15 to 25 parts of konjac glucomannan, 10 to 20 parts of multi-element dietary fiber powder, 5 to 10 parts of compound probiotic powder, 3 to 8 parts of bitter gourd polypeptide, 3 to 8 parts of folium mori extract and 2 to 5 parts of protein hydrolysate. Multi-element dietary fiber powder, prebiotics and the like are combined, endogenous GLP-1 is stimulated, the characteristics that the protein nutrient is not easily absorbed by people, but can be utilized by intestinal flora to generate SCFA and stimulate GLP-1 secreted by L cells at the far end of the intestinal tract are fully exerted, the requirements of most people for weight losing and weight control can be met, the protein nutrient can serve as a source of DDP-IV inhibitory peptide, decomposition of the endogenous GLP-1 is slowed down, and the weight losing and weight control effects are achieved. A more lasting effect of endogenous GLP-1 is ensured; a hot extrusion embedding technology and an airflow cutting technology are adopted, so that more nutrient substances can be effectively reserved in intestinal tracts at the same time, and nutrients are provided for flora.

The invention provides a microcapsule for improving alcoholic liver injury as well as a preparation method and application of the microcapsule. The microcapsule is obtained by embedding octacosanol and pueraria flavone by taking compound polysaccharide of lycium barbarum polysaccharide and konjac glucomannan as a microcapsule wall material.

The invention discloses a frozen surimi antifreeze agent, a preparation method thereof and an application of the frozen surimi antifreeze agent in improving the quality of frozen surimi. The antifreeze agent is prepared from soybean oligosaccharide and konjac glucomannan. According to the present invention, the compound ultrasonic condition is used for surimi freezing, such that the surimi freezing resistance can be significantly improved, the storage quality index of surimi can be well controlled, the surimi protein freezing denaturation can be effectively prevented, and the surimi gel property and the freezing quality can be improved; in the freezing storage process, the quality of the minced fillet treated by the antifreeze agent is obviously better than that of a blank control group. And the freezing deformation of protein in the surimi can be effectively retarded by adding the antifreeze agent and adopting a compound ultrasonic method, the quality of the surimi is ensured, and the shelf life is effectively prolonged. The method disclosed by the invention is convenient to apply, relatively simple in process steps, low in production cost, low in equipment requirement, high in operability and suitable for large-scale industrial application.

The invention belongs to the technical field of functional polymers, and particularly relates to a high-water-absorption konjac hydrogel polymer and a preparation method thereof. The konjac hydrogel polymer is prepared from the following raw materials in parts by weight: 30 to 40 parts of acetylated konjac glucomannan, 10 to 15 parts of modified chitosan, 5 to 8 parts of calcium chloride solution, 1 to 3 parts of acetic acid solution, 3 to 5 parts of nano cellulose, 2 to 5 parts of beewax, 10 to 15 parts of MCT medium chain triglyceride and 1 to 3 parts of emulsifier. According to the invention, through acetylation modified konjac glucomannan, hydrophilicity is reduced, water absorption is delayed, and stability of an acidic environment is improved; the mechanical strength is enhanced through crosslinking, the hydrophobicity is improved through chitosan modification, and the mechanical strength and toughness are improved through nanocellulose; the surface is coated with a beeswax and MCT mixture to adjust the surface property and delay water absorption; an interface induction method is combined with a freeze-drying technology to generate a porous structure, so that the water absorption efficiency and the structural integrity are improved.

The invention discloses a method for preparing high-purity mannan oligosaccharide from konjac fine powder, which comprises the following steps: washing the konjac fine powder with alcohol, treating with alpha-amylase and glucoamylase, degrading konjac glucomannan by using a compound enzyme consisting of beta-glucanase and beta-mannase, and finally adjusting the pH value to an isoelectric point to prepare the high-purity konjac mannan oligosaccharide. According to the method, high-content impurities such as starch, protein and alkaloid in the konjak fine powder are removed, the problem of accumulation control of konjak processing byproducts is solved, the utilization rate and the economic value of konjak resources are improved, and the source of mannan oligosaccharide is enriched. The method realizes recycling of the konjac fine powder, has the advantages of being simple in process, low in equipment requirement and suitable for industrial production, and can be popularized and applied on a large scale.

The invention relates to the field of food, and provides low-fat high-protein stretched cheese and a preparation method thereof.The preparation method comprises the steps that raw milk is subjected to standardization treatment, and standardized feed liquid is obtained; performing sterilization treatment on the standardized feed liquid to obtain a sterilized product; cooling the sterilized product, and uniformly mixing the cooled sterilized product with konjac glucomannan to obtain a mixture; adjusting the pH value of the mixture to 5.8-6.0 by using an acidifying agent to obtain acidified feed liquid; inoculating the acidified feed liquid with a leavening agent, and carrying out pre-fermentation treatment to obtain a pre-fermentation product; the pre-fermentation product is subjected to curdling treatment, whey removal treatment, heaping treatment, salting treatment, blanching stretching treatment and maturing treatment, and the low-fat high-protein stretched cheese is obtained. The stretched cheese disclosed by the invention not only has low fat content and high protein content, but also has excellent melting property, wire drawing property and flavor and mouth feel, is equivalent to the traditional high-fat cheese, and meets the requirements of consumers.

The invention provides a self-repairing coating of a touch screen and a preparation method of the self-repairing coating, the self-repairing coating is formed by curing sol formed by konjac glucomannan and POSS (Polyhedral Oligomeric Silsesquioxane) modified nano silicon dioxide, and the content of the POSS modified nano silicon dioxide is gradually reduced from the surface of the self-repairing coating to the inside. The self-repairing coating is of a multi-layer stacked structure formed by sequentially coating the surface of the touch screen with sol containing POSS modified nano silicon dioxide with different concentrations and curing the sol. The content of POSS modified nano silicon dioxide on the surface layer of the self-repairing coating is relatively high, more active sites such as amino groups and hydroxyl groups can be provided to serve as anchoring points of dynamic hydrogen bonds or dynamic chemical bonds, the repairing strength of a damaged interface is improved, and the repairing efficiency is improved.

The invention discloses oxidized konjac glucomannan and hydrazide hyaluronic acid composite hydrogel. The oxidized konjac glucomannan and hydrazide hyaluronic acid composite hydrogel is prepared from oxidized konjac glucomannan, hydrazide hyaluronic acid, neomycin sulfate, cannabidiol and 2-roots alcohol. The invention further provides a preparation method of the oxidized konjac glucomannan and hydrazide hyaluronic acid composite hydrogel and application of the oxidized konjac glucomannan and hydrazide hyaluronic acid composite hydrogel in preparation of hemostatic materials. The composite hydrogel disclosed by the invention has high adhesion and excellent antibacterial property, is suitable for various wounds, and has excellent effects of stopping bleeding, relieving pain, reducing wound infection and promoting wound healing.

The invention discloses a composition for treating intractable skin infection, sores and ulcers and inflammation as well as a preparation method and application of the composition, and belongs to the technical field of functional compositions. The composition is prepared from the following components in parts by mass: 1 to 5 parts of baicalin, 0.5 to 3 parts of antibacterial alkaloid, 2 to 6 parts of asiaticoside, 3 to 8 parts of salvianolic acid B, 1 to 4 parts of gallic acid, 5 to 10 parts of rhizoma bletillae polysaccharide, 3 to 10 parts of konjac glucomannan, 3 to 5 parts of chitosan, 8 to 20 parts of glycerol, 0.5 to 2 parts of genipin, 1 to 3 parts of calcium chloride, 1 to 3 parts of laurocapram and 40 to 80 parts of water. The antibacterial alkaloid comprises berberine or phellodendrine. Based on deep understanding of an intractable skin pathological mechanism, the components are scientifically matched, and the composition shows a remarkable synergistic effect in in-vitro antibacterial, anti-biofilm and anti-inflammatory experiments. The preparation process is simple, low in cost and suitable for industrial production.

The invention provides a composite hydrogel for promoting diabetic bone regeneration, the composite hydrogel is composed of L-histidine modified chitosan, oxidized konjac glucomannan, Zn and nano clay, and in-situ gelation is realized through coordination regulation, interlayer exchange and dynamic covalent bond synergistic effect. Through combined application of coordination regulation, interlayer exchange and dynamic covalent bonds, on-demand staged delivery of various ions is realized. According to the innovative design, the adhesive property and mechanical integrity of the hydrogel at a defect part are maintained, intelligent response can be realized according to the change of a bone microenvironment, and the defect that a single release mechanism in the prior art is difficult to meet the complicated demand of diabetic bone regeneration is overcome.