4 results about "Oral Granules" patented technology

The present invention discloses a medicine and food homologous composition for conditioning pain according to syndrome differentiation and its preparation method, belonging to the technical field of medicine and food homologous health products. The composition includes a general basic pain-relieving formula and special formulas for three syndromes, namely qi stagnation and blood stasis type, cold-dampness obstruction of collaterals type, and liver-kidney deficiency type. It follows the compatibility of monarch, minister, assistant, and envoy, and accurately adapts to more than 80% of the population with neck, shoulder, waist, and leg pain. The general formula is used for basic pain-relieving conditioning, and the three special formulas respectively achieve targeted conditioning of promoting blood circulation to remove blood stasis, warming meridians to dispel cold, and tonifying the liver and kidney to strengthen tendons and bones for the corresponding syndromes; the preparation methods are divided into two categories: oral administration (granules, powders, tablets) and external hot compress packs, and the process is standardized and can be scaled up; the product has been tested with a total effective rate of ≥96.7%, is safe without side effects, has high stability, realizes syndrome differentiation and conditioning, and accurate pain relief, and can be directly used for the conditioning and prevention of neck, shoulder, waist, and leg pain.

This invention relates to the field of pharmaceutical preparations, specifically providing anhydrous rimantadine hydrochloride granules and a method for preparing the same. The anhydrous rimantadine hydrochloride granules are a mixture of drug-containing taste-masked granules and flavor-correcting granules. The drug-containing taste-masked granules comprise rimantadine hydrochloride and a taste-masking material, wherein the taste-masking material is a lipid or waxy material. This invention, by selecting a lipid or waxy material as the taste-masking material and mixing it with rimantadine hydrochloride to prepare drug-containing taste-masked granules, and then mixing them with flavor-correcting granules, effectively masks the taste and allows for direct swallowing without water, greatly improving medication adherence, especially suitable for children, the elderly, and other individuals with swallowing difficulties. Furthermore, the preparation method of this invention is simple, requires minimal equipment, is low-cost, and suitable for large-scale production.

The invention discloses a plant compound preparation for relieving children cough and asthma and airway inflammation and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations. The preparation is prepared from a modified sophora flower bud extract, a fermented pericarpium citri reticulatae extract and a low-sensitivity tussilago farfara extract according to the weight ratio of 1: (3-4): (0.8-1.2), quercetin in the modified sophora flower bud extract is quantified to be 1.2%-2.0% through a high performance liquid chromatography method, and small molecule hesperidin in the fermented pericarpium citri reticulatae extract is quantified to be 2.5%-3.5% through a liquid chromatography-mass spectrometry method. The tussilagone in the low-sensitivity tussilago farfara extract is quantified to be 0.8%-1.5% through a gas chromatography-mass spectrometry method. A mild process is adopted for preparation, the preparation is an oral granule special for children, the dosage is fixed according to ages, the safety is high and the compliance is good through experimental verification, the cough and asthma recurrence rate is reduced through multi-target cooperation, and the pharmaceutical composition is suitable for children of 3-12 years old.

The invention discloses a preparation method and application of a traditional Chinese medicine spray for treating asthma, and belongs to the technical field of traditional Chinese medicine preparations. The stability problem of the traditional Chinese medicine spray is systematically solved through the synergistic effect of alcohol precipitation impurity removal, volatile oil clathration, pH regulation and control and the ternary stabilizer. Pharmacodynamic studies show that the spray can remarkably reduce the inflammatory factor level of asthma model mice and prolong the incubation period of asthma inducing of guinea pigs, has the effect better than that of oral granules, takes effect quickly and is suitable for quick relief in the acute attack period of asthma.