38 results about "Oral Granules" patented technology

The invention discloses fish oytocin oral granules and preparation and using methods thereof, and belongs to the technical field of fish culture. Aiming at the problems of difficult hormone delivery, complex operation, high cost, low ecbolic efficiency, high parent fish death rate and the like in artificial propagation of certain small fishes, the invention provides an artificial ecbolic method, which avoids fish stress response death and is high in ecbolic rate, easy, convenient, feasible and low in cost. The method comprises the following steps of: dissolving oytocin into normal saline, spraying the solution to an aquatic granulated feed, preparing the fish oytocin oral granules by wrapping a layer of animal grease containing vitamin E on the surface of the aquatic granulated feed, feeding the fishes with the oytocin oral granules in the propagation season of the fishes, and delivering the external hormone to parent fishes when the fishes actively eat the oral granules to induce gonad maturation, laying and fertilization of the parent fishes. The oral granules and the method are mainly applied to the artificial propagation of certain small fishes.

The invention belongs to the technical field of biological medicine, and particularly relates to an oral surface modification bile acid granule, composition of entrapped treatment medicine in the granule and a preparation method. Firstly, a positively charged compound of entrapped treatment medicine is prepared; then, a bile acid polymer with negative ions is used for coupling to form granules. Abile acid-phospholipid compound is inserted into a wrapped granule surface to form the bile acid modified granule. The medicine wrapped granule can be lipidosome, micelle, emulsion, microspheres, nanometer particles and the like. After the granule is orally taken in the body, the granule is selectively absorbed into blood in the intestinal tract under the effect of enterohepatic circulation; the bioavailability of oral medicine can be improved. The medicine is prepared from gene, protein, polypeptide, antibodies, nucleic acid, viruses and small molecule medicine.

The invention relates to an oral medicament for treating cardiovascular and cerebrovascular diseases, in particular to traditional Chinese medicine oral granules for treating the cardiovascular and cerebrovascular diseases, which are prepared by taking plant Chinese herbal medicines as raw materials. The traditional Chinese medicine oral granules are characterized in that the traditional Chinese medicine oral granules comprise the following active pharmaceutical ingredients in parts by weight (unit: g): 100-200 parts of unprocessed sanchi, 50-150 parts of American ginseng, 50-150 parts of fleece-flower root, 50-150 parts of hawthorn, 50-150 parts of eucommia, 50-150 parts of peach seed, 50-150 parts of cassia seed and 200-300 parts of salviae miltiorrhizae radix. The medicines are cleaned, air-dried and ground into powder (special grinding for pharmacies), and one spoon, namely about 10g of the traditional Chinese medicine oral granules is blended into decoction with boiled water for oral administration before sleep at night. All the medicines are compatible and complement mutually, thereby having the effects of activating blood circulation, removing blood stasis, dissipating the blood stasis, detumescence, moisturizing intestine, relaxing bowels, lowering lipid, reducing weight, clearing heart, relieving restlessness, nourishing blood for tranquillization, regulating immunity, bacteriostasis, preventing cancers, reducing blood pressure and regulating blood lipid, realizing synergism of efficacy, effectively restoring cells, clearing garbage in blood, gradually dissolving cholesterol and blood lipid on the walls of blood vessels, eliminating atherosclerotic blood lipid precipitation on the walls of the blood vessels, improving the elasticity of the blood vessels and having significant efficacy for treating the cardiovascular and cerebrovascular diseases.

The invention relates to a traditional Chinese medicinal preparation for treating presbyopia which is prepared from 15 concentrated traditional Chinese medicines as follows: 20-30 parts by weight of astragalus, 20-30 parts by weight of americanwater plantain, 20-30 parts by weight of korean ginseng, 20-30 parts by weight of angelica, 20-30 parts by weight of barrenwort, 20-30 parts by weight of rhizoma curculiginis, 20-30 parts by weight of atractylodes, 20-30 parts by weight of schizonepeta spike, 20-30 parts by weight of clematis root, 20-30 parts by weight of traditional chinese medicine hyssop, 20-30 parts by weight of liriope, 20-30 parts by weight of medlar and 20-30 parts by weight of rehmanniae radix, 5-10 parts by weight of asarum, 5-10 parts by weight of schisandra chinensis. The 15 concentrated traditional Chinese medicines have same concentration rate (for example, 5:1) and are weight rate, the preparation shape is oral granule shape traditional Chinese medicinal preparation. Presbyopic glasses can be took off at the soonest 10 days by taking the preparation for reading and writing, augen deepness recovers to normal augen range after being ophthalmic testing, optic nerve has full nourishment, all users need not wearing presbyopic glasses in five years follow up. The traditional Chinese medicinal preparation fills in the gaps that no medicine can cure natural presbyopia at present, and lower cost carries gospel to ordinary old person.

The invention belongs to the field of medicine and pharmacology, and is Pharmaceuticals oral granule. The Aceclofenac granule is made by raw material drug aceclofenac, findings and disintegrant. The Aceclofenac granule is phenyl acetic acid non-steroidal anti-inflammatory agent. It has notable anti-inflammatory, analgesic and antipyretic effect. It applies to the treatment of various rheumatoid arthritis, atrophic arthritis, osteoarthritis and spondylitis. It is fit for pain and fever caused by various diseases, and the toxic and side effects is lower than other varieties. Aceclofenac has not granule in prior medicine market; it is innovative formula and benefit for absorbing drug to getting better curative effect and better taste. It is safe, reliable and new drug for treatment of acute, chronic pain and anti-inflammation.

The invention discloses preparation for a genetic modified rice formulation and application thereof. The preparation includes steps of A. acquiring specific promoter for rice endosperm and semaphore peptides thereof; B. constructing special expressing carrier and of rice albuminous cell; C. fusing protein with codon of target gene, optimizing, synthesizing with gene; D. fusing with construction of protein expressing carrier pOsPMP26; E genetically transforming rice gene; F. highly expressing selection of genetic modified plant; G. processing seeds of genetic modified rice, and producing into oral tablets and oral granules by pellet mill. And an application of genetic modified rice formulation in preparing medicament for treating or preventing sugar diabete and hyperglycaemia is also disclosed. The inventive method is easy to implement, convenient to operate, low in preparation cost, safe, non-toxic, and has great efficacy.

A preparation method of oral granules for improving pet hair quality comprises the steps of Chinese herbal medicine extraction, nutritional functional bag preparation, mixing, primary preparation and after-preparation. The problems that vitamins are unstable and the palatability is affected are solved through a water-in-oil-in-water process, the water-in-oil-in-water emulsion is prepared into an outer surface layer through pressure spray drying, the outer surface layer has good palatability, an inner core wraps unstable substances, and the taste is masked, the palatability of pets is improved, meanwhile nutrient components are digested and absorbed, protein absorption of pet hair is promoted, smoothness and brightness of fur are improved, skin inflammation is reduced, and immunity is enhanced.

The invention belongs to the field of medicines and particularly relates to blood lipid reducing oral composition and a preparation method thereof. The blood lipid reducing oral composition is prepared from raw materials by weight as follows: 130-160 parts of flos sophorae, 9-12 parts of flos carthami, 9-12 parts of semen cassia, 90-110 parts of mint, 90-110 parts of pericarpium citri reticulatae, 6-10 parts of inulin and 2-5 parts of balanophyllia sp. The composition can be in the form of oral liquid or oral granules and is prepared with an aqueous extraction method. The composition has a higher regulation function on the blood lipid level, has a long-acting effect and is good in safety.

The invention discloses a preparation method of gynecological preoperative bowl-cleansing oral granules and solves the problems in gynecological preoperative treatment. The preparation method is characterized in that the granules are made with, by weight, 10-30 parts of horseweed herb, 6-12 parts of cinnamon seeds, 3-10 parts of Chinese mosla, 6-12 parts of Chinese starjasmine stem, 3-10 parts of loofah sponge, 6-12 parts of Barbary wolfberry fruit, 6-12 parts of Dipsacus root, 6-12 parts of grassleaf sweelflag rhizome, 6-12 parts of sunflower flower, 1-5 parts of Turbo cornutus solander, 3-10 parts of ox horn bone, and 10-25 parts of magnesium sulfate. The preparation method includes: 1, extracting essential oil for use from the rough powders of the Dipsacus root, cinnamon seeds and loofah sponge; 2, crushing the Turbo cornutus solander and ox horn bone into fine powder for use; 3, adding water to decoct the horseweed herb, Chinese mosla, Chinese starjasmine stem, Barbary wolfberry fruit, sunflower flower and grassleaf sweelflag rhizome for two times, filtering, combining filtrate, condensing the filtrate, adding ethanol to allow for sedimentation, taking supernate, recovering the ethanol, and condensing to obtain thick paste; 4, adding the essential oil obtained in the step 1, the fine powder obtained in the step 2 and magnesium sulfate into the thick paste obtained in the step 3, mixing well to obtain granules, and drying the granules. Clinical experiments show that the granules have good effect of gynecological preoperative bowel cleansing and is worthy of clinical application and popularization.

The invention discloses a pharmaceutical composition for treating leukocytopenia and immune hypofunction caused by radiotherapy and chemotherapy and a preparation method of oral granules of the pharmaceutical composition. The pharmaceutical composition is characterized in that the pharmaceutical composition comprises the following raw materials in parts by weight: 20 parts of rhizoma polygonati, 5 parts of ginseng, 5 parts of hericium erinaceus, 10 parts of palmleaf raspberry fruits, 10 parts of angelica sinensis, 10 parts of sanguisorba officinalis, 10 parts of fructus ligustri lucidi, 10 parts of jujube, 10 parts of peanut coats and 10 parts of pericarpium citri reticulatae. Systematic observations on clinical and scientific research cases show that the pharmaceutical composition has the effects of replenishing qi to invigorate the spleen, nourishing yin and enriching essence, enriching the blood and invigorating the circulation of blood, and has an ideal therapeutic effect on both qi-yin deficiency type leukocytopenia and immune hypofunction caused by radiotherapy and chemotherapy.

The invention discloses a preferred method for treating clinical diseases by using levosalbutamol sulfate oral granules so as to reduce adverse reactions and improve safety.

The invention belongs to the field of medicine, and especially relates to an anti-depressant drug and its oral particulate agent and a pharmacy purpose thereof. The anti-depressant drug is prepared bya pharmaceutical adjuvant, mirtazapine and an isoquinoline compound. The pharmaceutical adjuvant of the oral particulate agent comprises mannitol, hydroxypropyl methyl cellulose, citric acid and aspartame. With low dosage usage of mirtazapine, the anti-depressant drug can perform obvious anti-depression effect and has good safety.

The invention discloses oral granules for treating the mumps and a preparation method thereof.The oral granules are prepared from codeine, aristolochic acid, robinin, syringic acid, paeonol, mint distillate, riboflavin, pentosans, nabumetone, nitrofurantoin, allantoin, water-soluble araboxylan, mixed amino acid, cyclodextrin and alcohol and other auxiliaries including sweetening agent, disintegrant and lubricant.Various western medicine components are reasonably combined, and the oral granules have functions of resisting infection, clearing away heat and toxic materials, and calming and stopping pain, can eliminate parotid gland swelling, resist virus infection and meanwhile enhance immunity of organism to promote the rapid rehabilitation of a patient, are easy to prepare and convenient to use and have quite good clinical application prospects.

The invention belongs the field of pharmacy, and particularly relates to a pharmaceutical composition for treating post-myocardial-infarction ventricular remodeling. The pharmaceutical composition fortreating the post-myocardial-infarction ventricular remodeling is prepared from pharmaceutically acceptable pharmaceutic adjuvants, quercetin and miltefosine, wherein 209-435 parts by weight of quercetin and 20-28 parts by weight of miltefosine are used. The dosage form of the pharmaceutical composition for treating the post-myocardial-infarction ventricular remodeling is an oral solid preparation and is preferably an oral granule preparation. When quercetin and miltefosine are combined for drug administration, miltefosine has an unexpected synergistic effect on the post-myocardial-infarctionventricular remodeling resistance effect of quercetin.

The invention discloses an American ginseng oral granule capable of effectively improving the immunocompetence of a human body. The American ginseng oral granule comprises the following raw materials in weight part: 50-100 parts of American ginseng, 50-60 parts of pseudo-ginseng, 100-120 parts of mythic fungus, 30-40 parts of longan aril, 20-30 parts of white sugar, 20-30 parts of Chinese magnoliavine, 20-30 parts of tuber of dwarf lilyturf, 15-30 parts of honey-fried licorice root, 30-40 parts of lilium brownie, 5-10 parts of edible bird's nest, 9-15 parts of radix ophiopogonis, 9-15 parts of fructus schisandrae, 30-40 parts of pseudo-ginseng, 45-55 parts of red sage root, 9-15 parts of fritillaria cirrhosa, 9-12 parts of glehnia root, 12-15 parts of bletilla rhizome, 10-15 parts of bighead atractylodes rhizome, 10-20 parts of poria cocos, and 1-3 parts of Cordyceps sinensis. According to the technical scheme of the invention, the American ginseng oral granule mainly has the effects of replenishing the Qi, invigorating the spleen and replenishing the vital essence and the blood, so that the efficacies of promoting the yin-yang balance of the human body, blending the Qi and the blood, and treating both symptoms and root causes are realized. The American ginseng oral granule, prepared as a pure Chinese drug preparation, is remarkable in curative effect, simple and feasible in process, low in price, and good in taste.

The invention belongs to the field of medicines and in particular relates to a traditional Chinese medicine composition for treating posterior circulation stroke and a preparation method of the traditional Chinese medicine composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 30 to 70 parts of radix astragali seu hedysari, 5 to 30 parts of radix rehmanniae, 5 to 30 parts of Chinese angelica root, 5 to 30 parts of rhizoma chuanxiong, 5 to 20 parts of rhizoma cimicifugae, 5 to 20 parts of wheat bran, 5 to 20 parts of leech and 0.1 to 0.4 part of herb of achnatherum inebrians. The preparation method adopts an alcohol-extraction and water-deposition method and a preparation is an oral granule preparation. The traditional Chinese medicine composition provided by the invention has unexpected treatment effect on the posterior circulation stroke and has relatively small side effect.