This invention discloses the application of a pharmaceutical composition containing curculigoside in the treatment of type 2
diabetic nephropathy, belonging to the technical field of
diabetic nephropathy drugs. The pharmaceutical composition uses curculigoside and
astragaloside A as active ingredients, and also includes pharmaceutically acceptable excipients, wherein the
mass ratio of curculigoside to
astragaloside A is 1:0.2 to 1:1.5. This invention is the first to apply curculigoside to the treatment of type 2
diabetic nephropathy. Through the synergistic effect of curculigoside and
astragaloside A, it can significantly improve
renal function in patients with type 2 diabetic
nephropathy, inhibit inflammatory responses and
oxidative stress, reduce renal
pathological damage, and
delay the progression of
renal fibrosis. Furthermore, the pharmaceutical composition has high safety, no obvious adverse reactions, diverse dosage forms, and high
medication adherence, overcoming the shortcomings of existing therapeutic drugs with limited
efficacy and numerous adverse reactions, and has significant
clinical value and broad application prospects.