20 results about "Medication adherence" patented technology

Most therapeutic treatments require dose adjustment after initial administration. Dosage adjustment is crucial to ensuring optimal safety and efficacy characteristics of the treatment. Gene therapy is inherently limited by the inability to adjust the dose after initial administration. This invention describes a genetic element capable of dose adjustment after the initial administration of gene therapy. The realization of dose adjustment allows for the replacement of multiple subcutaneous protein injection regimens with single-injection gene therapy, thereby improving pharmacokinetics, safety / efficacy characteristics, medication adherence, and reducing healthcare costs.

This invention proposes an intelligent menopausal patient health management platform, comprising a doctor-patient interaction unit, an information processing unit, a pharmaceutical service unit, and a medical terminal. The doctor-patient interaction unit allows patients to conveniently fill in initial diagnosis information, including questionnaire data and medication information, on a mobile terminal, achieving effective collection of information from outside the hospital. The information processing unit can perform structured processing of this information. Based on risk assessment results and medication information, the pharmaceutical service unit can intelligently generate a pharmaceutical service plan including medication rescheduling suggestions, individualized medication guidance, and follow-up reminders. This not only improves the accuracy and safety of medication use but also enhances patient medication adherence through continuous follow-up reminders. The medical terminal provides medical staff with an integrated view of patient information, enabling them to comprehensively understand the patient's initial diagnosis information, system-generated risk assessment results, and pharmaceutical recommendations, and efficiently respond to complex patient questions.

A nebulizer monitoring system and a medication adherence monitoring method. The nebulizer monitoring system includes a nebulizer and a remote monitoring platform. The nebulizer has a mouthpiece. The nebulizer includes a nebulizing module, a sensing assembly, and a control module. The control module is electrically connected to the nebulizing module and the sensing assembly. The remote monitoring platform includes a computing module. The computing module is configured to analyze and calculate at least two adherence parameters and generate a breathing pattern. The control module is configured to adjust a nebulizing frequency and an aerosol volume of the nebulizing module based on the breathing pattern.

This invention discloses a multimodal health management method and system for TIPS postoperative care, specifically relating to the field of medical and health management technology. It involves constructing a postoperative multimodal follow-up dataset by collecting patient health consultation records, dietary protein intake records, oral medication adherence records, and doctor-patient feedback records. Through consultation topic classification, protein intake deviation identification, medication adherence breakpoint detection, and feedback tendency determination, a set of behavioral events is extracted. Within the same follow-up period, co-occurrence associations of consultation, diet, medication, and feedback events are established to generate a risk trigger chain for hepatic encephalopathy. Based on the risk trigger chain, the intervention type is determined, generating individualized intervention instructions such as dietary guidance, medication reminders, and health consultation responses. These intervention instructions are then pushed to both the patient and healthcare professionals, collecting execution and treatment feedback and writing it back into the dataset to form a closed-loop follow-up update. Finally, the updated data is used to correct the risk trigger chain and automatically generate intervention instructions for the next cycle.

This invention discloses a method for medication risk warning and dynamic intervention using a smart pillbox for elderly patients with chronic diseases, relating to the fields of intelligent medical devices and chronic disease management technology. The method first constructs four types of chronic disease knowledge graphs: medication behavior, physiological indicators, drug interactions, and environmental conditions. Then, it processes the graphs using a GNN module with a GRU-like gating mechanism, weightedly fusing multi-time-step features using a time-step attention mechanism, and integrating similar patient features based on Jaccard similarity to generate comprehensive risk features. During the training phase, the risk level and type are output after feature optimization using a collaborative attention mechanism. In the inference phase, a similarity propagation mechanism is used to address the cold-start problem for newly enrolled patients, matching a three-level intervention rule base to generate personalized strategies, and iteratively optimizing the model based on intervention feedback. This invention achieves proactive and precise warning and dynamic intervention, improving risk assessment performance and patient medication adherence in different scenarios.

This invention provides a heterocyclic compound, its preparation method, and its use in preparing GLP-1 receptor agonist prodrugs with oral and long-acting pharmacokinetic properties, belonging to the field of medicinal chemistry. The compound provided by this invention can be used as a GLP-1 receptor agonist prodrug, which can release a parent drug with GLP-1 receptor agonist activity through hydrolysis in vivo. The compound provided by this invention can be used as a GLP-1 receptor agonist prodrug compound for the preparation of drugs for the prevention and / or treatment of GLP-1 receptor-related diseases. The compound of this invention exhibits good oral and long-acting pharmacokinetics, resulting in better medication adherence and broad application prospects.

This invention discloses an IoT-based intelligent monitoring and medication reminder system for military personnel with chronic diseases, relating to IoT medical technology and military medical and health technology. It includes a terminal monitoring module, an intelligent medication reminder module, a cloud data processing platform, and a medical collaboration module. The terminal monitoring module collects physiological indicator data and medication-related status data from military patients with chronic diseases. The intelligent medication reminder module, through scene recognition and dynamic adjustment mechanisms, perfectly adapts to military training tasks. Relying on motion sensors to identify training scenarios, it automatically switches to a low-interference reminder mode of vibration + text, avoiding auditory warnings from interfering with training. Simultaneously, it dynamically adjusts the priority of medication reminders according to training intensity, delaying reminders for non-urgent medications until training breaks to ensure no reminders are missed or disruptive. Combined with a three-level early warning mechanism, it improves medication adherence and solves the problems of traditional reminder methods being singular and easily interfered with during training.

This invention provides a method for preparing natural nanophases of a Uyghur medicine compound preparation for treating eczema and its application. Based on a patent (CN201911308259.1) for a compound preparation for treating skin inflammation, this method regulates the solvent composition, concentration conditions, and mixing method of the extraction system to form a stable multiphase structure. Further, differential centrifugation is used to achieve directional separation of phases with different particle sizes, thereby obtaining natural nanophases. The obtained natural nanophases enrich the active ingredients in the compound preparation, significantly reduce cytotoxicity, and enhance biocompatibility. Simultaneously, they significantly inhibit NO production and exhibit eczema-related antibacterial activity, improving drug absorption and utilization efficiency, thus demonstrating superior eczema-related biological activity. This method also addresses the issue of the darker color of the product obtained from the original preparation process, improving the acceptability of the preparation and medication adherence.

This invention discloses the application of a pharmaceutical composition containing curculigoside in the treatment of type 2 diabetic nephropathy, belonging to the technical field of diabetic nephropathy drugs. The pharmaceutical composition uses curculigoside and astragaloside A as active ingredients, and also includes pharmaceutically acceptable excipients, wherein the mass ratio of curculigoside to astragaloside A is 1:0.2 to 1:1.5. This invention is the first to apply curculigoside to the treatment of type 2 diabetic nephropathy. Through the synergistic effect of curculigoside and astragaloside A, it can significantly improve renal function in patients with type 2 diabetic nephropathy, inhibit inflammatory responses and oxidative stress, reduce renal pathological damage, and delay the progression of renal fibrosis. Furthermore, the pharmaceutical composition has high safety, no obvious adverse reactions, diverse dosage forms, and high medication adherence, overcoming the shortcomings of existing therapeutic drugs with limited efficacy and numerous adverse reactions, and has significant clinical value and broad application prospects.

This invention relates to the field of intelligent medical information technology, providing an information-based planning system for acne patients based on the IMB model. The system collects facial acne characteristics, medication adherence, and facial oil characteristics data from acne patients. It constructs a gridded oil-matching medication adherence index and a gridded acne condition index. Through oil secretion gradient weighted fusion and dynamic condition calibration, it outputs the facial gridded drug utilization rate results. Furthermore, it identifies the influencing factors of each facial grid and performs spatial aggregation to generate medication adherence planning instructions that match the individual's facial region characteristics. This invention forms a closed-loop process from condition gridded perception, multi-dimensional behavior quantification, drug utilization rate attribution assessment to regional targeted intervention. It achieves refined and intelligent acne medication management based on differences in facial oil secretion and lesion aggregation characteristics, significantly improving the accuracy of individualized intervention for acne patients' topical medication behavior.

The application discloses a kind of for managing the drug management system and method of tracking patient drug remaining amount, belong to medical information technology field.The system includes center server, doctor terminal, pharmacy terminal, inventory calculation and tracking engine, intelligent early warning module and patient terminal.Its core is through inventory calculation and tracking engine, according to the medication regimen in electronic prescription, and combining with the medication data fed back by patient, the real-time estimated remaining amount of drug is dynamically calculated.Intelligent early warning module monitors the remaining amount and the estimated remaining days, medication adherence rate and other indicators derived therefrom, and automatically triggers graded early warning when preset conditions are met.The application realizes the precise, automatic tracking and active early warning of patient individual drug inventory, effectively solves the problem of drug discontinuation or waste caused by traditional reliance on human memory, provides objective medication data support for doctors, and thus improves medication safety, treatment continuity and medical service quality.

This invention belongs to the field of pharmaceutical formulations, specifically relating to a levocarnitine oral gel and its preparation method. This invention discloses a stable levocarnitine oral gel composition comprising levocarnitine, a gel matrix, an alkali metal salt, and sodium polyacrylate. The stable levocarnitine oral gel disclosed in this invention is easy to swallow, has good medication adherence, does not undergo dehydration and shrinkage during the observation period, has stable product quality, good safety, and is convenient to carry and use; the process is simpler, with high production efficiency and lower risk, making it suitable for large-scale industrial production.

This invention relates to the field of pharmaceutical preparations, specifically providing anhydrous rimantadine hydrochloride granules and a method for preparing the same. The anhydrous rimantadine hydrochloride granules are a mixture of drug-containing taste-masked granules and flavor-correcting granules. The drug-containing taste-masked granules comprise rimantadine hydrochloride and a taste-masking material, wherein the taste-masking material is a lipid or waxy material. This invention, by selecting a lipid or waxy material as the taste-masking material and mixing it with rimantadine hydrochloride to prepare drug-containing taste-masked granules, and then mixing them with flavor-correcting granules, effectively masks the taste and allows for direct swallowing without water, greatly improving medication adherence, especially suitable for children, the elderly, and other individuals with swallowing difficulties. Furthermore, the preparation method of this invention is simple, requires minimal equipment, is low-cost, and suitable for large-scale production.

To provide a method for continuously recording a medication state of a patient.SOLUTION: Firstly, a patient photographs a two-dimensional code 111 recorded on a document 110 and generates (S201) prescription information 300. If the prescription information 300 is generated for the first time (S202), an alarm setting screen is displayed (S203). Then, a device 100 transmits (S204) at least one section of the prescription information 300 to a server 120. The server 120 transmits (S205) an alarm to the device 100 at the time set as an alarm time for each medicine. The medicine is displayed that should be administered as a content of the alarm, and by tapping or clicking and selecting a display element for recording medication history when the medicine has been administered, the device 100 can transmit (S206) the medication history to the server 120.SELECTED DRAWING: Figure 2

This will enable us to support the best possible dispensing of medications from the perspective of patient medication adherence. [Solution] The system includes a dispensing history management unit 11 that collects and manages dispensing history information, including prescription information and dispensing information performed by the dispensing pharmacy, from multiple pharmacy terminals 2; a dispensing schedule information acquisition unit 13 that acquires dispensing schedule information, including prescription information and information on planned dispensing, from the pharmacy terminals 2 to which information will be provided; and an information provision unit 14 that compares the dispensing schedule information of the target dispensing pharmacy with the dispensing history information of other dispensing pharmacies and provides the target dispensing pharmacy with dispensing-related information identified according to the similarities and differences between the dispensing schedule information and the dispensing history information. This allows the target dispensing pharmacy to make a final decision on the content of dispensing, taking into account the patient's medication adherence, by referring to dispensing-related information acquired from the dispensing support device 1, even for the same prescription, where there is a range of choices in the content of dispensing performed by the dispensing pharmacy.

This invention provides a pediatric Xiaochaihu granule and its preparation method. The Xiaochaihu granules are prepared from a dry extract powder of a traditional Chinese medicine composition, sucrose, soluble starch, and flavoring as raw materials. The weight ratio of the total weight of sucrose and soluble starch to the weight of the dry extract powder of the traditional Chinese medicine composition is (2-5):1, the weight ratio of sucrose to soluble starch is 1:1.5-1.5:1, and the weight ratio of flavoring to the dry extract powder of the traditional Chinese medicine composition is (0-5):(100-500). The dry extract powder of the traditional Chinese medicine composition is prepared by extracting the active ingredients from the raw materials and then drying the resulting extract. Through optimized formulation, this invention's Xiaochaihu granules maintain a good taste while significantly reducing the total amount of excipients and sucrose. It also ensures that the prepared Xiaochaihu granules are uniform in size and appropriately firm, improving children's medication adherence and safety, and reducing the risk of inactive excipient intake and excessive sucrose intake in children during clinical medication use.

This application discloses a method, apparatus, and electronic device for calibrating medication status based on interactive feedback, relating to the field of medical information processing technology, and particularly to the field of chronic disease management. The method includes: collecting interactive feedback data between the user and an interactive system; performing semantic parsing on the interactive feedback data using a large language model to obtain feature information related to the user's actual medication status; determining a dynamic adherence coefficient based on the feature information, the dynamic adherence coefficient being used to characterize the user's real-time execution of the medication plan; and calibrating the user's medication status estimation model online based on the dynamic adherence coefficient to obtain a target medication status, wherein the target medication status includes an updated estimate of the remaining medication. This application solves the technical problem of distorted medication adherence assessment caused by relying solely on medication purchase behavior to infer medication status in existing technologies.

The present application relates to the technical field of medical health information and speech synthesis, and specifically discloses an intelligent voice reminding system for medication compliance of cataract patients, which comprises a user interaction terminal, a cloud collaborative processing platform and a medical data interface. The user interaction terminal determines the user's interactive state through multi-modal perception and local behavior recognition and reports it; the cloud platform dynamically decides the reminding time and content strategy through a dynamic strategy decision unit based on the user portrait, the medication task and the user state, and synthesizes personalized voice content by a multi-modal content generation unit for broadcasting. The system realizes precise timing reminding by sensing the user state, and dynamically generates differentiated reminding content based on the personalized portrait, effectively alleviating reminding fatigue, improving the acceptance of reminding and the efficiency of medication compliance management.

The utility model belongs to the technical field of medical treatment and public health, and particularly relates to a manual quantitative medicine box device which comprises a medicine box body. The medicine box body is divided into the upper layer and the lower layer through the partition plate, the seven containing boxes on the upper layer are magnetically connected and used for storing doses of one week, the partition walls are arranged in the containing boxes and used for taking medicine for several times every day, and the lower layer is a storage area and used for storing large-package medicine corresponding to the doses of the upper layer and an alarm clock and displaying time. When the cover is opened, the alarm clock can be automatically turned off through the controller, the lamp is turned off, and the ring is turned off, so that the flexibility of the medicine box is greatly improved, the medicine dosage and the taking frequency can be accurately loaded according to the illness state and the doctor's advice, and when the illness state changes, the medicine can be conveniently taken. The medicine can be reloaded at any time, the dynamic treatment requirement is met, the medication compliance of a patient is remarkably improved, and it is ensured that disease treatment is coherent and effective.

An inhaler tracking device for use with an inhaler or cannister configured to release a substance upon actuation includes a housing including a chamber for receiving the inhaler or cannister, the housing configured to hold the inhaler or cannister at a predetermined orientation, plural sensors sensing plural conditions or events including those of the inhaler or cannister, at least one indicator providing feedback to a user, and a controller configured to receive data from the plural sensors, analyze dispensing from the inhaler or cannister based on the received data, and output feedback signals to the at least one indicator. The analyzing includes determining duration and / or intensity of shaking of the device prior to dispensing, orientation of the device during dispensing, and number of actuations of the inhaler or cannister.