142 results about "Ph regulation" patented technology

The invention particularly relates to printing and dyeing wastewater advanced treatment equipment and a method thereof. The equipment comprises a pretreatment unit, an electrolysis unit, a pH regulation unit, a post-treatment unit and a comprehensive monitoring unit, the pretreatment unit comprises a physical filtering device and an advanced oxidation pretreatment device and is used for removing suspended solids and macromolecular organic matters; the electrolysis unit is provided with a current control module and a salinity adjusting module and is used for degrading organic pollutants and disinfecting and sterilizing; the pH adjusting unit is provided with a pH sensor and a pH correction pump and is used for accurately controlling the pH value change in the treatment process; the post-treatment unit comprises an ultrafiltration membrane and activated carbon and is used for removing residual micromolecular organic matters and trace heavy metal ions; the comprehensive monitoring unit integrates a PLC controller, a data acquisition module and a communication interface, and is used for realizing automatic management and remote monitoring of the system.

The embodiment of the invention provides a hydrochloric acid PH control device in a germanium oxide production process and a control method thereof, and belongs to the field of chemical process automatic control. The device comprises an acid liquor storage tank used for storing raw liquor hydrochloric acid and connected to an acid mixing tank through a raw acid feeding control valve; the acid mixing tank is used for mixing an acid solution with a diluent and is connected to the pH regulation reaction tank through a mixed acid feeding control valve; the alkali liquor storage tank is connected to the pH regulation reaction tank through an alkali liquor adding control valve; the pH regulation reaction tank is used for receiving the mixed acid liquor and the alkali liquor and regulating the pH value of a reaction system, and is provided with a pH sensor for detecting the pH value in real time; and the control unit is used for dynamically adjusting the opening degree of each valve by adopting an improved fuzzy self-adaptive PID control algorithm according to a detection result of the pH sensor so as to control the pH value to be within a target range. According to the scheme, the problems of overshoot and lag caused by traditional fixed parameter PID adjustment are solved, and therefore the stability of the pH value of the solution and the consistency of the technology in the germanium oxide production process are guaranteed.

The invention relates to the technical field of metal amino acid chelate preparation, and discloses high-bioavailability magnesium glycinate and a preparation method thereof.The method comprises the steps that a glycine solution and a magnesium salt solution are mixed, the initial pH value is adjusted to be within the alkaline range, and a low-polarity organic phase is added to construct a two-phase solvent system; dynamically adjusting the pH value of the reaction system by stages, and sequentially inducing amino and carboxyl of glycine to chelate magnesium ions step by step to form a chelate; and blending the chelated product with a chitosan-sodium alginate composite carrier, and carrying out spray drying to obtain magnesium glycinate particles. The molar ratio of magnesium ions to glycine in the chelating structure of magnesium glycinate is 1: 3. Through the synergistic effect of dynamic pH regulation and a two-phase solvent system, directional synthesis of the magnesium glycinate 1: 3 high-coordination chelate is achieved, the bioavailability and the targeted slow release performance are remarkably improved by combining a composite carrier nano embedding technology, and meanwhile, the process is efficient and environmentally friendly.

The invention relates to the technical field of water treatment, in particular to a composite flocculant for tunnel construction wastewater treatment and a preparation method thereof. The method comprises the following steps: carrying out a reaction on triethanolamine and isocyano ethyl methacrylate to prepare tertiary amine acrylate; reacting tertiary amine acrylate with methoxyl-polyethylene glycol-chlorine to prepare polyethylene glycol modified quaternary ammonium salt acrylate; further reacting with methyl dichlorosilane to prepare a modifier; and compounding the modifier with hydrotalcite, sodium silicate and an iron-magnesium-calcium mixed solution to prepare the composite flocculant. The flocculant realizes efficient flocculation and pH regulation through mechanisms such as electric neutralization and adsorption bridging, has the characteristics of quickly gathering suspended particles, reducing sludge yield and improving floc compactness and dehydration performance, is suitable for treatment of high-concentration suspended solids and slightly alkaline wastewater, shows comprehensive advantages of high efficiency, economy and environmental protection, and has wide application prospects. The field treatment requirements of tunnel construction wastewater are met.

The invention discloses a preparation method of a vitamin C liposome preparation capable of improving encapsulation efficiency, the vitamin C liposome preparation is prepared by an ethanol injection-high pressure microjet circulation homogenization method, the homogenized liposome is small in particle size and uniform in distribution, and meanwhile, by combining a dialysis purification and buffer agent pH regulation process, the encapsulation efficiency of the vitamin C liposome preparation is improved. The prepared vitamin C liposome preparation can still keep high stability under the condition that cholesterol is not contained, and the problem that in the prior art, a vitamin C liposome preparation is low in encapsulation efficiency is effectively solved.

The invention discloses a method for detecting soil active organic carbon based on fluorescence spectrometry, and belongs to the technical field of soil detection. The method comprises the following steps: sequentially drying, sieving and grinding fresh soil to obtain a soil sample, and sequentially performing active organic carbon extraction, purification, decoloration and pH regulation on the soil sample to obtain a soil liquid to be detected. The method comprises the following steps: adding fluorescein into a soil liquid to be detected to form a soil internal standard detection liquid, obtaining a soil fluorescence spectrum through three-dimensional fluorescence spectrum scanning, carrying out background deduction and correction coefficient correction, and calculating the active organic carbon concentration of the soil by using tryptophan, tyrosine and SMP fluorescence concentration standard curves. According to the method, an internal standard method is combined with a fluorescence spectrum technology, and through multi-step sample pretreatment and spectrum correction, the detection accuracy and the anti-interference capability are improved, the active organic carbon concentration of the soil can be rapidly and accurately determined, and an effective means is provided for soil carbon cycle research and quality evaluation.

The invention belongs to the technical field of detection methods, and provides a method for determining the content of amino acid in chyme in digestive tracts of livestock and poultry, which comprises the following steps: mixing a sample and a peroxyformic acid solution, and reacting to obtain an oxidation system; mixing the oxidation system, a hydrochloric acid solution and a chelating agent solution, and hydrolyzing to obtain a hydrolysis system; mixing the hydrolysis system and alkali liquor, then adjusting the pH value, and then mixing with acid liquor to obtain liquid to be detected; centrifuging the to-be-measured liquid, filtering, injecting a filtering system and the mixed amino acid standard liquid into an automatic amino acid analyzer, and measuring. According to the method, a certain amount of disodium ethylene diamine tetraacetate is added to chelate heavy metals in chyme in digestive tracts of livestock and poultry, and meanwhile, the heavy metals and redundant impurities are removed by adopting the steps of centrifuging, filtering and the like, so that the accuracy of amino acid detection is ensured, and the addicability of digestible amino acid content in daily ration is better. The hydrolysate is treated by adopting simple steps such as pH regulation and centrifugation, so that the operation process is simplified, and the operation error is reduced.

The invention discloses a preparation method of an aluminum hydroxide adjuvant capable of regulating and controlling pH in stages, and aims to solve the problems of non-uniform particle size, unstable adsorption and large inter-batch difference in the traditional process. According to the method, phosphate radical modified hydroxyapatite nanocrystal seeds are taken as an induction template, and three-stage accurate pH regulation and control are carried out: a pre-crystal seed stage activates crystal seed active sites, a main crystallization stage guides directional growth of aluminum hydroxide, and an aluminum phosphate coating layer is formed in a stabilization stage. Compared with a traditional process, the finished product yield is improved, energy consumption is reduced, and the method is suitable for vaccine industrial production.

The invention discloses fresh spirulina fermentation liquor with rose fragrance and a preparation method of the fresh spirulina fermentation liquor. The method is characterized in that 5% glucose, lactic acid bacteria, saccharomycetes and spore lactobacillus (10: 2: 1: 1) are adopted for composite fermentation of a bacterial liquid, dynamic pH regulation (4.5-6.0) and gradient fermentation (2-6 days) are combined, and synthesis of phenethyl alcohol flavor substances is promoted; the optimal fermentation process conditions are established, the phenethyl alcohol content reaches up to 547.52 mu g / kg, the oxidation resistance is remarkably improved, and the aroma and nutritional ingredients can be stably kept for 12 months under the refrigeration condition. According to the method, the problem that the fishy smell of algae is shielded is solved, and a novel aroma conversion path is constructed through strain metabolism regulation, so that the spirulina fermentation liquor has the natural flower fragrance and the nutrient enrichment characteristic. The method is low in cost, green, environmentally friendly and free of chemical additives, conforms to the development trend of healthy food, provides a new technical normal form for deep processing of algae, and has remarkable market competitiveness and industrialization value.

The invention discloses a difunctional composite preparation capable of rapidly and deeply removing calcium ions and synchronously adjusting pH, and belongs to the field of sewage treatment preparations. The novel bifunctional composite preparation provided by the invention has the capability of rapidly and deeply removing Ca < 2 + > and adjusting pH by utilizing high-concentration Ca < 2 + > in-situ induced crystallization on the surface of the calcium ion-rich adsorbent powder and the buffering property of oxalic acid and phosphate radicals; the bifunctional composite preparation is put into a pressure filtrate with the influent Ca < 2 + > concentration of 1800 mg / L and the pH value of 12.4, and after static settlement is performed for 30 min, the effluent Ca < 2 + > concentration is lower than 1000 mg / L, and the pH value is lower than 9.

The invention provides a preparation method of ultra-pure electrolytic iron, which comprises the following steps: (1) sequentially carrying out pH regulation and ion exchange on an iron electrolyte to obtain an iron electrolysis filtrate; (2) the iron electrolysis filtrate obtained in the step (1) is placed in a first electrolytic cell to be subjected to first electrolysis, and an electrolytic iron crude product is obtained; and (3) the iron electrolysis filtrate obtained in the step (1) is placed in a second electrolytic cell to be subjected to second electrolysis, and the ultra-pure electrolytic iron is obtained. A second anode in the second electrolytic cell is an electrolytic iron crude product obtained in the step (2). According to the preparation method, the ultra-pure electrolytic iron with the purity larger than or equal to 5N can be prepared, meanwhile, the production process is simple, convenient and efficient, and the production cost is low.

The invention discloses a green preparation method for realizing a high-performance chitosan film through pH regulation and control of a citric acid buffering agent, and belongs to the field of food packaging and high polymer materials. According to the method, a water phase separation method is adopted, a citric acid buffering agent serves as a water phase environment, and a chitosan solution is induced to be subjected to phase separation and gelation by regulating and controlling the pH value (preferably 5.0-5.5) of the citric acid buffering agent. The preparation method comprises the following specific steps: dissolving chitosan powder in an alkali urea solvent (KOH: urea: water = 7: 12: 81), inducing gelation through a citric acid buffer agent, carrying out solvent replacement through an ethanol solution, and drying and curing. According to the method, a chemical cross-linking agent does not need to be used, and the core is that a buffer system is used for regulating and controlling the phase separation process to promote aggregation among chitosan molecular chains, so that a compact physical structure network is constructed. The prepared chitosan film has excellent mechanical strength, water resistance, gas barrier property, biocompatibility and degradability, and is suitable for the fields of food, medicine packaging and the like.

The invention belongs to the technical field of solid waste resource utilization, and particularly relates to a red mud-based multifunctional water treatment agent and a preparation method thereof. The method comprises the steps of red mud dealkalization, drying and crushing, acid dissolution reaction, pH regulation and control, function enhancement, slow-release carrier forming and the like, and by introducing a modified polyacrylamide functional additive and a compound flocculant, the removal capacity of the treatment agent on heavy metal ions, organic pollutants and high-hardness ions is effectively improved; sodium alginate-polyvinyl alcohol is adopted to construct an ionic crosslinking type slow release system, so that the combination of long-acting release and broad-spectrum purification functions is realized. Compared with the prior art, the method has the advantages that resource utilization of the red mud waste is achieved, and the prepared water treatment agent has the remarkable advantages of being stable in structure, high in adaptability, high in treatment efficiency and the like.

The invention discloses a process for preparing a multifunctional liquid fertilizer from tylosin waste liquid, and belongs to the technical field of fertilizer preparation. The method comprises the following steps: pretreating the tylosin waste liquid to obtain pretreated waste liquid; adjusting the pH value of the pretreated waste liquid to obtain the pH-adjusted waste liquid; sterilizing and filtering the waste liquid subjected to pH regulation to obtain pure treatment liquid; the pure treatment liquid is subjected to nutrient substance blending, and the multifunctional liquid fertilizer prepared from the tylosin waste liquid is obtained. According to the method, a tylosin degradation catalyst is synthesized in the waste liquid in the pretreatment and pH adjustment processes, tylosin in the waste liquid is degraded in the sterilization process, and soil pollution caused by residual tylosin in the waste liquid is prevented while the steps are shortened; in the blending of the nutrient substances, the acidic substances are added to chelate metal ions, so that the release of the nutrient substances in the fertilizer is delayed, the resource utilization rate is increased, and the fertilizer is worthy of wide-range popularization.

The invention provides a directional recovery method of pickling wastewater. According to the treatment method disclosed by the invention, a decomplexing agent is used for promoting a complex of fluorine, iron, chromium and nickel to be dissociated into free fluorine, then nanofiltration is adopted for realizing separation of the free fluorine, the iron, the chromium and the nickel, and a fluorine removal agent is added into the separated fluorine-rich solution for realizing fluorine recovery, so that the problem that the complex fluorine is difficult to recover is solved; meanwhile, according to the treatment method, a reducing agent is added into a separated solution rich in iron, chromium and nickel to promote ferric ions to be reduced into ferrous ions, then ion exchange resin is used for preferentially adsorbing chromium and nickel, the ion exchange resin containing chromium and nickel is subjected to desorption treatment, and then graded recovery of chromium and nickel is achieved through gradient pH regulation and control. And finally, pH regulation and control are carried out on the effluent obtained after ion exchange resin adsorption, iron recovery can be achieved, and therefore the problem that separation is difficult due to the fact that the pH of iron and chromium precipitates is close is solved.

The invention discloses an Apopsin3 mutant and a method for regulating an environment in a plant cell to be acidic, and belongs to the technical field of pH regulation in the plant cell. The regulation and control method comprises the following steps: mutating 83rd and 120th amino acids of the light-operated hydrogen ion pump protein Apopsin3, converting into hydrogen ion channels, expressing the hydrogen ion channels on a cell membrane in a targeting manner, and stimulating with green light of 40-500 [mu] W / mm < 2 > and 520-560 nm so as to regulate the pH in the cell to be acidic. By adopting the cell specific promoter and performing site-specific mutagenesis modification on the specific hydrogen ion pump, accurate pH regulation and control on specific cells or organelles can be realized. An Apopsin3 (FARH) gene is fused with a cell membrane targeting sequence, and under the stimulation of specific light, only the pH of cytoplasm is obviously changed, and the pH of other cell regions is not influenced.

The invention provides a method for synergistically removing impurities through pH regulation and complexing of ionic rare earth ore leachate, the ionic rare earth ore leachate is stirred and mixed uniformly, a plant polyphenol sulfonic acid derivative complexing agent is added, the complexing agent is prepared through sulfonation, neutralization, concentration and drying by taking gallic acid as a raw material, and the complexing agent can automatically regulate the pH value of the solution and stabilize the pH value at 5.1-5.3; under the condition, phenolic hydroxyl groups, carboxyl groups and sulfonic functional groups in complexing agent molecules preferentially form stable precipitates with impurity ions such as Al < 3 + > and Fe < 3 + > in the leachate, and the complexing effect with rare earth ions (RE < 3 + >) is weak; and after the reaction is completed, carrying out solid-liquid separation to obtain the purified leachate and impurity-containing precipitation slag. The method solves the problem of ammonia nitrogen pollution caused by use of ammonium bicarbonate, ammonia water and other ammonium salts in the traditional process, is a novel method with high impurity removal rate, simple process flow and environmental friendliness, and is suitable for industrial application.

The application discloses a bifidobacterium splitting activity detection method based on pH regulation and application thereof, and belongs to the technical field of microbial fermentation. The detection method comprises high-density fermentation of bifidobacterium with fluorescent labeling under pH regulation and splitting cycle detection through flow cytometry, and the pH regulation range is 4.30-6.30. The bifidobacterium splitting activity detection method based on pH regulation and application thereof can quickly and accurately quantitatively and qualitatively detect the real-time fermentation state of bifidobacterium. The bifidobacterium splitting activity detection method based on pH regulation can be used for quantitative evaluation of cell splitting in a complex fermentation system, and realizes bifidobacterium fermentation optimization and precise fermentation control.

The invention relates to the technical field of biological detection, and discloses a tyrosinase activity detection method based on in-situ fluorescence generation and application, and the method comprises the following steps: mixing L-tyrosine with 3-hydroxyphenylboronic acid; adding a biological enzyme sample solution, incubating at a constant temperature, and accumulating L-dopa by enzyme catalysis; then adding an alkaline adjusting solution to construct an alkaline environment, inducing the 3-hydroxyphenylboronic acid and L-dopa to generate a specific boric acid esterification reaction, and generating a fluorescent borate compound in situ; and finally, adding a constant-volume stop solution to maintain an alkaline environment and complement the volume, and detecting the fluorescence intensity. According to the method, a step-by-step pH regulation strategy is adopted, the enzyme activity is guaranteed under the neutral condition, then color development is promoted under the alkaline condition, and the problem that dynamic conditions of the two are incompatible is solved. The method has the advantages of low background interference, high sensitivity, good reproducibility and the like by utilizing specific recognition of a phenylboronic acid group on a catechol structure, and can be applied to food browning analysis, whitening drug screening and disease diagnosis.

The invention discloses a production method for improving the ring opening rate of monascus milovastatin, and belongs to the technical field of monascus rice production. According to the method, a monascus purpureus high-yield strain is selected and inoculated into a solid indica rice matrix containing a specific additive for fermentation after spore activation, and the matrix comprises 1, 5-p-coumaroylquinic acid, sodium acetate, sodium citrate, a thermally modified soybean protein isolate polysaccharide sulfate compound and other components. Wherein sodium acetate and sodium citrate can serve as short-chain fatty acid precursors, the activity of closed-loop lactonase is inhibited through pH regulation, and generation of lactone type products is reduced; 1, 5-p-coumaroylquinic acid activates the expression of a polyketide synthase gene cluster, so that the synthesis flux of the Monacolin K with an open-loop structure is improved; nicotinamide ribose enhances the electron transfer efficiency of glycolysis and TCA circulation, provides sufficient ATP for polyketone synthesis, and promotes synthesis of Monacolin K. The compound further strengthens the synthesis flux of secondary metabolites by changing the form of hyphae and continuously releasing a nitrogen / carbon source, and promotes intracellular products to be transferred to extracellular.

The invention relates to a selective cell killing device based on surface and interface pH regulation and application thereof. The method comprises the following steps: depositing a noble metal material capable of regulating and controlling extracellular proton concentration on one side of a substrate to form a regulation and control layer, and connecting the regulation and control layer to an external preset dynamic voltage control unit through a wire; the regulation and control layer is attached to the surface of the tissue; a dynamic voltage is periodically applied to the regulation and control layer through an external preset dynamic voltage control unit, so that the pH value of the interface microenvironment of the regulation and control layer and tissue cells is alternately changed between 5 and 8, and accurate selective killing of the cells is realized. A preset dynamic voltage control scheme based on a cancer cell glycolysis oscillation period is adopted, so that the pH value of a local surface interface can be regulated and controlled according to a set period, the excretion of lactic acid and protons of cancer cells is continuously and effectively interfered, and the cancer cells are prevented from generating adaptive reaction.

The invention belongs to the technical field of sodium chloride production, and particularly relates to an automatic control method and device for an acidification process of medicinal sodium chloride. The method comprises the following steps: transmitting a brine acid adding pH value and a metering pump frequency conversion signal to a DCS (Distributed Control System), and tracking in real time by the DCS; detecting the pH value of the brine to be subjected to acid adjustment through a static mixer; calculating the required acid adding amount; the DCS outputs a 4-20mA direct current signal in direct proportion to the acid adding amount to the alternating current frequency converter; the AC frequency converter converts the control signal into a corresponding frequency to control the metering pump; the purpose of controlling the acid adding amount is achieved by controlling the rotating speed of the metering pump; and controlling the pH value of the brine within a qualified range, and entering a subsequent process. According to the invention, sustainability, monitorability and high-precision control of the brine acidification process in the production process of the medicinal sodium chloride can be realized, the pH regulation and control precision can reach + / -0.3, the pH uniformity of refined brine and the stability of the production process and the product quality are improved, the safety of the working environment is improved, and the labor cost is reduced.

The invention relates to a pretreatment and deep pretreatment water treatment hardness removal method which comprises the following steps: providing an adjusting tank, adding wastewater into the adjusting tank, and pretreating the wastewater in the adjusting tank, so that liquid in the adjusting tank reacts and precipitates; carrying out solid-liquid separation on the wastewater in the regulating tank to obtain a primary reaction solution, adding the primary reaction solution into a reaction tank, carrying out pH regulation on the primary reaction solution in the reaction tank, and adding sodium carbonate into the reaction tank, so that the primary reaction solution in the reaction tank reacts and precipitates; adding the first reaction liquid in the reaction tank into a tubular membrane for solid-liquid separation to obtain a second reaction liquid, intercepting a precipitate after a chemical reaction of the second reaction liquid through the tubular membrane, and removing scaling substances; and adding the separated second reaction liquid into a resin unit to obtain a third reaction liquid, and carrying out hardness removal on the second reaction liquid through the resin unit.

The invention provides an RGI pectin dissolution promoting preparation method based on pH regulation and control. The technical prejudice that the extracting solution is adjusted to be neutral before alcohol precipitation in the original common means is overcome, the pH value of the extracting solution before alcohol precipitation is adjusted to be 1-3 so as to influence the structural form of the RGI pectin, the anti-aggregation ability of the whole system is enhanced, the purpose of promoting dissolution of the hot-dried RG-I pectin is achieved, and the method has good industrial application prospects.

The invention provides a recombinant collagen separation and purification method based on multi-layer filtration, and belongs to the technical field of biotechnology and purification and separation. The multi-layer filtration-based recombinant collagen separation and purification method comprises the following steps: pretreatment, pH adjustment, anion exchange chromatography, reversed-phase polymer filler chromatography, decoloration and concentration liquid exchange. According to the method, the fermentation liquor is centrifuged and filtered, large-particle impurities such as cell debris are effectively removed, then the fermentation liquor is subjected to pH regulation treatment, and an optimal pH environment is provided for subsequent chromatography; the anion exchange chromatography and the reversed-phase polymer filler chromatography are respectively used for efficiently removing impurities with negative charges, impurities with weak polarity and part of free pigments, then the pigments combined in the recombinant collagen are decolored, and finally, the decolored fermentation liquor is subjected to concentration and liquid exchange. Therefore, a high-purity recombinant collagen solution is obtained.

The application provides a grey water PH regulating device, relates to the technical field of PH regulation, and comprises an adjusting tank and a filtering device, a water inlet pipe is fixedly connected to one side of the adjusting tank, a water outlet is fixedly connected to the lower end of the one side of the adjusting tank, a filtering device is arranged on the inner wall of the adjusting tank and corresponds to the position of the water inlet pipe, the filtering device comprises a filtering pipe, the two ends of the filtering pipe are slidably connected with the inner wall of the adjusting tank, mounting plates are fixedly connected to the two ends of the filtering pipe, sliding blocks are fixedly connected to the two sides of the mounting plates, sliding grooves are formed in the inner wall of the adjusting tank and correspond to the positions of the sliding blocks, and the surfaces of the sliding blocks are slidably connected with the inner walls of the sliding grooves. The filtering device, the stirring device and the gas exchange device are designed, so that the problem that the traditional filtering device is inconvenient to disassemble and clean, is easy to cause the mesh holes to be blocked by sundries, affects the water inflow, and has low PH regulation precision is solved.

The invention relates to nano-engineered bacillus subtilis as well as a preparation method and application thereof, and belongs to the technical field of biology. Aiming at the technical problems of low probiotic delivery efficiency, insufficient regulation and control of enteropathogenic bacteria and single ROS (reactive oxygen species) removal in the prior art, a ternary composite system of chitosan-coated bacillus subtilis bridged WO3 (at) PDA nanoparticles is constructed. The preparation method comprises the following steps: carrying out auto-polymerization on dopamine hydrochloride and WO3 nanoparticles to form a WO3 (at) PDA core-shell structure; the method comprises the following steps: coating bacillus subtilis with chitosan through pH regulation to form BSCS; and finally, preparing the BSCS-coated WO3-coated PDA complex microbial inoculant through electrostatic interaction bridging. Experiments show that the preparation can relieve inflammatory symptoms of mice with DSS-induced colitis and effectively realize intestinal micro-ecological reprogramming. The invention provides a novel nano-probiotic synergistic treatment system for IBD treatment.

The invention provides pH regulation systems of buffer-loaded hydrogels that can regulate pH of solutions for long periods of time. These pH-regulating hydrogels may be used in a variety of pH-dependent systems, including water treatment, agricultural soil, and biological applications. Demonstrated is an application in increasing the efficacy of weak base chemotherapeutics used for cancer treatments.

The invention relates to the technical field of bioengineering, in particular to a bionic modular in-vitro large intestine fermentation simulation model, an evaluation method and application. The large intestine fermentation simulation model is composed of a fermentation cavity module, a detachable mucus layer module, a detachable pH regulation and control module and a gas production monitoring module. The method comprises the following steps: constructing a modularized in-vitro large intestine fermentation simulation model, adding prebiotics and a basal culture medium, inoculating excrement homogenate, controlling parameters in an anaerobic fermentation process, monitoring the gas yield in the fermentation process, and determining the composition of metabolites and intestinal flora after fermentation is finished. The system adopts an anti-interference material and a dynamic environment control technology, so that the stability of anaerobic conditions is ensured, and the problems of material degradation and ion pollution of a traditional device are avoided. And the experiment flux and efficiency are greatly improved. The device has excellent reuse performance, key parts still keep stable functions after being sterilized for multiple times, the maintenance cost is remarkably reduced, and the consistency and repeatability of experimental data are guaranteed.

The invention discloses a coal chemical industry wastewater treatment device, and relates to the technical field of industrial wastewater treatment equipment, the coal chemical industry wastewater treatment device comprises a box body and a pH adjusting assembly, a first partition plate is arranged in the box body, and the first partition plate divides the interior of the box body into a first reaction zone and a second reaction zone. The pH adjusting assembly comprises a lifting box, a pH detection part and an acid-base injection pipe, the lifting box is provided with a liquid storage tank, the lifting box is slidably connected with the first partition plate and can take liquid from the first reaction area through the liquid storage tank during sliding, and the pH detection part can detect the pH value of liquid in the lifting box when the lifting box gets close; the acid-alkali injection pipe is arranged on the box body and can inject acid liquor or alkali liquor into the lifting box according to the pH value detected by the pH detection part. The pH detection piece of the coal chemical industry wastewater treatment device can accurately detect the pH value of liquid in the liquid storage tank of the lifting box in real time, so that acid liquor or alkali liquor is accurately injected into the lifting box through the acid-alkali injection pipe according to an actual detection result to carry out pH regulation, and pH regulation and control are accurate and high in efficiency.