689 results about "Photothermal effect" patented technology

The invention discloses a near-infrared emission aggregation-induced emission organic photo-thermal molecule and a preparation method and application thereof, and belongs to the technical field of biomedicine, and the structure is shown as a formula I: # imgabs0 # (I), wherein R1, R2, R3, R4, R5 and R6 are independently selected from groups containing alkyl chains. The invention also provides a preparation method of the organic photo-thermal molecule and application of the organic photo-thermal molecule in preparation of multifunctional protein nanoparticles with near-infrared aggregation-induced emission. The near-infrared emission aggregation-induced emission organic photo-thermal molecule provided by the invention shows excellent near-infrared imaging effect and photo-thermal capability under laser irradiation, and the obtained near-infrared aggregation-induced emission multifunctional protein nano particle has excellent photo-thermal effect and imaging resolution, has excellent targeting to brain tumor, and has good application prospects in blood brain barrier crossing, brain tumor targeting and brain tumor targeting. And tumor killing, photothermal and ferroptosis combined treatment has practical medical significance, and is expected to be widely applied to the aspects of intelligent drug delivery and nano medical treatment.

The invention discloses a laser heat effect evaluation method and device, and belongs to the technical field of biology. The method comprises the following steps: acquiring an original laser speckle blood flow image sequence, and analyzing an original laser speckle image by adopting a time contrast analysis algorithm to obtain a laser speckle contrast image; and converting the laser speckle contrast image to obtain a laser speckle blood flow image. Calculating the full width at half maximum of the blood vessel in the laser speckle blood flow image as the width of the blood vessel; subtraction is conducted on the blood flow image obtained after laser irradiation and the blood flow image obtained before laser irradiation, and a difference image is obtained; blood vessels with blood flow changes due to laser irradiation are obtained according to the difference image, then a region of interest is selected, the blood flow mean value of the blood vessels before and after laser irradiation is obtained, and therefore the final laser treatment effect is evaluated. The mouse spine window 108 is irradiated from the complete skin side of the mouse spine window 108, and the blood flow change is monitored in real time on the opposite exposed blood vessel side by adopting technologies such as laser speckle blood flow imaging and the like. The influence of the upper skin tissue is considered, the blood flow change is monitored in real time, and accurate evaluation of the blood vessel laser heat effect is achieved.

The invention provides an aggregation-induced emission molecule, a nano motor and a preparation method and application of the aggregation-induced emission molecule, the aggregation-induced emission molecule is used for near-infrared emission, has photo-thermal properties, and has the characteristics of near-infrared II region luminescence, heat production and good light stability; the nano motor is prepared by taking an asymmetric double-mesoporous nano material with different pore diameters as a support material and selectively loading aggregation-induced emission molecules on one side of the support material with a larger pore diameter; under the irradiation of near-infrared light, the aggregation-induced emission molecules with the photothermal effect can form a non-uniform thermal gradient to push the self-thermophoresis movement of the nano motor; tumor sites can be diagnosed and reported under the mediation of near-infrared II region imaging; through the photo-thermal effect, the motor can destroy tumor interstitial cells and degrade tumor matrix components; and in combination with autothermophoresis, blood vessels can be penetrated, so that penetration to the deep layer of the tumor can be realized.

The invention discloses a composite microbial enzyme preparation and a preparation method thereof, and belongs to the technical field of bioplastic degradation. The enzyme preparation is synergistically constructed through a temperature-sensitive MOFs / Schiff base network composite carrier and black phosphorus quantum dots, FeO (at) ZIF-8 is taken as a core, and PNIPAM is grafted on the surface to form temperature-responsive MOFs; constructing a three-dimensional network carrier through Schiff base crosslinking of the CMC and the CNF; the complex enzyme is loaded on MOFs pore channels and then is embedded in a carrier network together with the black phosphorus quantum dots. The temperature-sensitive MOFs open pore channels to release enzyme when the compost is heated, and the Schiff base network dissociates secondary released enzyme under an acidic condition; the black phosphorus quantum dots promote enzyme activity and strengthen carrier response through a photothermal effect; the compound enzyme contains cutinase, alkaline lipase, neutral lipase, alpha-amylase, saccharifying enzyme, cellulase, laccase and protease, and can synergistically degrade PLA, PBAT and starch-based plastic. According to the invention, dual environment response controlled release, photo-thermal synergistic catalysis and synergistic degradation of the enzyme preparation are realized, and the plastic degradation period is shortened under the composting condition.

The invention provides a photo-thermal super-hydrophobic energy storage material, a preparation method thereof and application of the photo-thermal super-hydrophobic energy storage material in anti-icing and deicing, and belongs to the technical field of anti-icing and deicing. The photo-thermal super-hydrophobic energy storage material provided by the invention comprises an energy storage coating and a photo-thermal super-hydrophobic layer which are sequentially arranged from bottom to top, the energy storage coating comprises the following components: first resin and phase change energy storage microcapsules distributed in the first resin; the components of the photo-thermal super-hydrophobic layer comprise second resin and a photo-thermal inorganic material distributed in the second resin; the surface of the photo-thermal super-hydrophobic layer is provided with a micro-nano structure. Efficient anti-icing / deicing is achieved through the synergistic effect of the photothermal effect, the energy storage characteristic and the super-hydrophobicity, and the result of the embodiment shows that the anti-icing duration of the coating prepared through the method reaches 1.5 times that of a traditional super-hydrophobic surface. Meanwhile, under the illumination condition, the temperature of the coating can be increased to about 50 DEG C within 2000 s, and ice can rapidly fall off from the surface of the coating.

The invention discloses a super-hydrophobic road ice-inhibiting coating based on a photothermal effect and nano modified particles and a preparation method of the super-hydrophobic road ice-inhibiting coating. The preparation method comprises the following steps: introducing silane modified nano silicon dioxide (SiO2) and titanium dioxide (TiO2) particles into a polyaniline solution, and preparing the composite super-hydrophobic powder through a chemical oxidation polymerization method. The preparation method comprises the following steps: firstly, modifying the surfaces of SiO2 and TiO2 nanoparticles by adopting a silane coupling agent, and endowing the SiO2 and TiO2 nanoparticles with low surface energy and hydrophobic property; and then adding the modified nano-particles into an aniline monomer solution, reacting with doped acid and an oxidizing agent, so that polyaniline molecules are subjected to in-situ polymerization on the surfaces of the particles, and the composite super-hydrophobic powder with a micro-nano structure is formed. The obtained composite material has excellent photothermal conversion performance and super-hydrophobic performance at the same time, and the efficient photothermal material heat absorption ice melting effect and the synergistic ice restraining effect of the photothermal material and the super-hydrophobic material can be achieved. Compared with a traditional ice-inhibiting coating, the coating disclosed by the invention shows stronger ice-resisting capability in a low-temperature and high-humidity environment, has good durability, mechanical stability and environmental protection property, and is suitable for the field of ice prevention and ice inhibition in cold regions such as roads, bridges, airport runways and the like.

The preparation method comprises the following steps: synthesizing gold nanostars (GNS) by using a seed growth method, coating mesoporous cerium dioxide (mCeO2) by using a template method, and loading a photosensitizer indocyanine green (ICG), so as to form a nano enzyme diagnosis and treatment system with chemical activity, photoactivity and photothermal effects. In the system, the gold nanostars have a good photo-thermal effect due to the multi-branched structure of the gold nanostars; on one hand, the mesoporous cerium dioxide coated on the outer layer has a chemical effect due to the nano-enzyme effect, and on the other hand, the mesoporous structure of the mesoporous cerium dioxide can better load the photosensitizer indocyanine green. All the components have good stability and biological safety, also have peroxidase simulation activity and a drug loading function, can improve the level of reactive oxygen species (ROS) in a tumor microenvironment and load photosensitizer drugs, and have an excellent anti-tumor effect and small side effects.

The invention discloses photo-thermal controlled-release nitric oxide anti-biofilm hydrogel based on click reaction crosslinking as well as a preparation method and application of the photo-thermal controlled-release nitric oxide anti-biofilm hydrogel based on click reaction crosslinking, the hydrogel is prepared by taking azide group-containing four-arm polyethylene glycol and alkynyl modified hyaluronic acid as matrixes through click chemistry rapid crosslinking under the catalysis of copper-based nanoparticles, the antibacterial biological membrane has remarkable dual anti-biological membrane and anti-inflammatory effects, and can be applied to wound treatment of bacterial biological membrane infection; through a wound surface coating form, under near-infrared light irradiation, copper nanoparticles generate a mild photothermal effect to remove a biological membrane, and Cu < 2 + > is released to promote fibroblast proliferation; nitric oxide can be controllably released, a biological membrane is synergistically eliminated by enhancing lipid peroxidation and destroying a bacterial membrane structure, meanwhile, angiogenesis is promoted, collagen deposition is stimulated, and the wound healing process is accelerated; the invention has the functions of efficient antibiosis and tissue regeneration, and has wide clinical application prospect and development value in the field of infectious wound treatment.

The invention provides a titanium nitride doped fluoride-free photo-thermal super-hydrophobic coating and a preparation method and application thereof.The titanium nitride doped fluoride-free photo-thermal super-hydrophobic coating is prepared from polydimethylsiloxane modified titanium nitride, hydrophobic nanoparticles and an adhesive and has the excellent local surface plasma resonance effect and photo-thermal effect; meanwhile, the coating is of a rough and uniform micro-nano hierarchical structure, dynamic water can be efficiently removed, icing can be delayed, the surface temperature can reach 12 DEG C only through irradiation of one sunlight intensity in the environment of-30 DEG C, and rapid deicing can be achieved. The coating has good functions of self-cleaning, anti-icing, deicing, defrosting and the like, renewable solar energy is utilized, and the coating is green, environment-friendly, energy-saving and emission-reducing. Meanwhile, the super-hydrophobic surface of the coating can effectively delay icing and inhibit ice adhesion. According to the coating, organic combination of an active deicing strategy and a passive deicing strategy is achieved based on the synergistic effect of the super-hydrophobicity and the photothermal effect.

The invention discloses a flow-type Raman sorting method and a high-luminous-flux flow-type Raman sorting device, and the method comprises the following steps: carrying out coincident focusing on Raman laser and near-infrared laser captured by a light trap to form a Raman excitation detection site, and arranging the Raman excitation detection site at the tip of the outer end of a tail end electrode in a chip dielectric focusing electrode; the photo-thermal oscillation near-infrared laser is focused on a tail end electrode in a dielectric focusing electrode of the chip and does not coincide with a Raman excitation detection site; through switching of light trap capture near-infrared laser and photo-thermal oscillation near-infrared laser, a single cell sample is captured and fixed at a Raman excitation detection site through light trap capture force generated by the light trap capture near-infrared laser or bubbles are generated through a photo-thermal effect generated by the photo-thermal oscillation near-infrared laser; the cell sample adhered to the tail end electrode in the dielectric focusing electrode is oscillated and separated through the bubbles. Compared with the prior art, the device has the beneficial effects that the organic combination of optical trap capture and dielectric capture sample oscillation functions can be realized, the switching is convenient, flexible, rapid, simple and reliable in use, the instrument cost is greatly reduced, the application range of the instrument is effectively widened, and the device has very strong universality.

The invention discloses a method and device for simultaneously detecting qnr1, qnr2 and qnr3 and application. A sample is irradiated by a coaxial reflection LED light source outside 808nm, a sensitizer Sb2WO6 coated NiS provides photoelectrons and heat for LAMP through light driving, a target gene is used as a template to initiate an amplification reaction, and a large number of double-chain DNALAMP light induction products are obtained. Sb2WO6 (at) NiS is modified by a nucleic acid chain to obtain a signal probe, an LAMP light-induced product and the signal probe are captured by a detection region in a sandwich form, a photo-thermal temperature change signal positively related to the content of the LAMP light-induced product is given, and qnr1, qnr2 and qnr3 in a sample are quantified according to the temperature change signal. Photoelectron and photothermal effects are generated by using the photoinduced activity of the sensitizer Sb2WO6 at NiS, the temperature is rapidly controlled, the sensitizer is in direct contact with an amplification system on a molecular level, then photothermal analysis test paper color development detection is performed, and the photothermal efficiency is remarkably improved.

The invention discloses an infrared photothermal imaging system and method in structured light illumination fluorescence detection, and belongs to the field of super-resolution imaging. The system comprises a structured light generation module, a fluorescence excitation module, a fluorescence collection module and a mid-infrared light thermal module. The structured light generation module generates structured light with adjustable phase and direction; the fluorescence excitation module inputs the structured light to a to-be-analyzed sample and excites the sample to emit fluorescence; meanwhile, infrared pulse laser can be input into a sample by utilizing a mid-infrared photothermal module, and the fluorescence intensity is modulated by utilizing a photothermal effect; finally, fluorescent light emitted by the sample is collected by a fluorescent light collecting module, and an infrared photothermal image in structured light illumination is obtained. The system breaks through the diffraction limit, the resolution ratio is increased by two times at most, the intrinsic infrared spectrum of the sample is obtained through mid-infrared photothermal imaging, and the chemical components and the structure of the sample are reflected. According to the invention, two technologies are combined, so that the intrinsic infrared spectrum information of the sample is provided under the sub-diffraction limit.

The invention discloses a range-limited light-operated anti-tumor composite hydrogel drug reservoir and a preparation method and application thereof.The light-responsive drug-loaded nano hydrogel is loaded into a temperature-sensitive hydrogel system to form the range-limited hydrogel drug reservoir with light-operated drug release, the preparation method comprises the steps that PEG, LA and GA are added into a three-necked flask for an oil bath reaction, and the temperature-sensitive hydrogel system is obtained; after the reaction, purifying and freeze-drying to obtain a PLGA-PEG-PLGA block copolymer; the PLGA-PEG-PLGA segmented copolymer is dissolved in ultrapure water, and a PLGA-PEG-PLGA sol is obtained; and dissolving the drug-loaded PDA (at) P (NIPAAm-co-AM) nano hydrogel into the PLGA-PEG-PLGA sol, so as to obtain the confined light-operated anti-tumor composite hydrogel drug reservoir. The confined light-operated anti-tumor composite hydrogel drug reservoir has light-responsive drug delivery performance, not only has space-time controllability of drug release, but also weakens the problems of photothermal effect and the like in light-assisted therapy, so that accurate tumor therapy can be realized.

The invention relates to the technical field of targeted cargo delivery, in particular to a drug loading and delivery method and a cell carrying method of a core-shell mesoporous micro-nano robot. The drug loading and delivery method is realized based on the drug loading capacity of the mesoporous structure, the magnetism of the iron oxide core and the photothermal effect of the polydopamine shell. The core-shell mesoporous micro-nano robot can adsorb and load drugs through capillary force and electrostatic force generated by the mesoporous structure of the core-shell mesoporous micro-nano robot; then, an external magnetic field is used for driving the device to move; near-infrared light is utilized to irradiate when approaching a targeted area, the temperature of a pore structure rises, and along with thermal vibration, drugs in mesopores are effectively released to the targeted area, so that the drug delivery effect is achieved. When the drug is loaded and delivered, the core-shell mesoporous micro-nano robot has carrying capacity after being clustered under a magnetic field, and cells are carried through an eddy current carrying method and a contact adhesion method. Targeted goods delivery of goods such as targeted drugs and cells can be achieved through the micro-nano robot.

The invention relates to the technical field of preparation of composite functional materials, in particular to a scale structure coating based on a PDMS / Co (at) SiO2 composite material and a preparation method and application of the scale structure coating. The preparation method comprises the following steps: mixing vinyl-terminated polydimethylsiloxane with methylhydrosiloxane to obtain a pre-polymerized solution; dispersing cobalt powder in the prepolymerization liquid to obtain a PDMS / Co mixture, coating the PDMS / Co mixture on the surface of a mold with a scale structure, and stripping the mold after curing to obtain a PDMS / Co scale array; and modifying SiO2 nanoparticles on the surface of the PDMS / Co scale array to obtain the scale structure coating based on the PDMS / Co coated SiO2 composite material. According to the invention, by constructing the multistage micro-nano structure and cooperating with the magnetic response and photothermal effect, a ''magnetostrictive unbalance-elastic rebound'' liquid drop directional transport mechanism and a photothermal-super-hydrophobic cooperative anti-icing function are constructed, and the problems of low energy efficiency, poor environmental adaptability and easy failure under extreme conditions of an existing anti-icing material are solved.

The invention provides a microneedle preparation for co-delivering photo-thermal nano-enzyme and elemene as well as a preparation method and application of the microneedle preparation. The preparation method comprises the following steps: firstly, preparing a novel photo-thermal nano enzyme Au (at) MoS2 through a two-step water phase synthesis strategy; benefited from the synergistic effect of the hybrid material, the nano-enzyme shows significantly enhanced near-infrared (NIR) photothermal effect, peroxidase-like (POD) activity and glutathione-like peroxidase (GSHOx) activity, and can effectively remodel the tumor microenvironment and destroy the redox steady state. Furthermore, photo-thermal nano enzyme, beta-ELE and hyaluronic acid are used as raw materials, and a novel soluble microneedle preparation is successfully prepared through a template method. The novel composite microneedle is in a sharp rectangular pyramid shape, growth of melanoma can be effectively inhibited through percutaneous delivery of photo-thermal nano-enzyme and beta-ELE, remarkable systemic toxicity is avoided, and an innovative strategy is provided for non-invasive, efficient and safe melanoma combined treatment.

The invention discloses a Cu2WS4-CuBi2O4 composite material with a photothermal effect and a preparation method and application thereof.The Cu2WS4-CuBi2O4 composite material is supported by CuBi2O4 of a rod-shaped structure, flaky Cu2WS4 is loaded on the surface of the rod-shaped CuBi2O4 through the interface regulation and control effect of a surfactant by adopting a hydrothermal method, and a Z-type heterojunction with the photothermal effect is formed; in an antibiotic degradation system, the Cu2WS4-CuBi2O4 composite material shows good photocatalytic performance and degradation effect under the synergistic effect of a photothermal effect and a PDS advanced oxidation process. The device is simple to prepare, stable in structure, high in repeatability and free of secondary pollution, and can meet laboratory and industrial requirements.

The invention discloses a preparation method of a super-hydrophobic antibacterial fabric with a photothermal effect, which comprises the following steps: firstly, loading a photothermal preparation on the surface of the fabric to endow the fabric with photothermal performance, and then introducing a composite coating formed by hydrophobic silicon dioxide nanoparticles and a silane coupling agent with an alkane chain, the surface energy of the material is reduced, a micro-nano coarse structure is constructed, and the antibacterial fabric with excellent photo-thermal and super-hydrophobic properties is prepared; the surface water contact angle of the prepared super-hydrophobic antibacterial fabric is 158 degrees, the surface temperature reaches 120 DEG C under the irradiation of near-infrared light, and the super-hydrophobic antibacterial fabric shows excellent photo-thermal cycling stability and super-hydrophobic high-temperature resistance; the antibacterial rate of the super-hydrophobic antibacterial fabric exceeds 99.0% under the synergistic effect of passive super-hydrophobic antibacterial adhesion and active photo-thermal sterilization, and the super-hydrophobic antibacterial fabric is wide in antibacterial range and long in antibacterial life.

The invention relates to the technical field of biological medicine, in particular to immunogen cell death enhanced nano-vesicle hydrogel and application thereof. The invention provides a 3D-printable multifunctional synergistic immunogen cell death enhanced nano-vesicle hydrogel, which is characterized in that SerMA hydrogel is used as a matrix, cell membrane nano-vesicles (N (at) ILO) loaded with a photothermal agent IR1061, a chemotherapeutic drug OXA and a tumor acidic microenvironment regulator Lon are encapsulated, initial tumor immunogen cell death is triggered through a photothermal effect, and the tumor immunogen cell death enhanced nano-vesicle hydrogel can be used for 3D printing. OXA further enhances the ICD effect, Lon regulates the acidic tumor microenvironment to improve the T cell activity, and postoperative multi-mode synergistic anti-tumor treatment is achieved; meanwhile, the hydrogel also has excellent photocuring 3D printing capability, can be used for individually constructing a filling structure matched with a postoperative defect area, has a wide application prospect, and provides a new strategy and theoretical basis for postoperative comprehensive treatment of choroidal melanoma.

The invention discloses a hybrid vesicle composition containing finasteride and nanogold. The composition is prepared from hair follicle stem cell outer vesicles, lipidosome, finasteride and nanogold, according to the method, the treatment efficiency of finasteride on androgenetic alopecia is enhanced by utilizing the delivery property of a mediated hair recovery mechanism pathway and a homing effect of heterozygous hair follicle stem cell outer vesicles to a hair follicle microenvironment and assisting with a photothermal effect provided by nanogold light conversion, and the method can be widely applied to the fields of medical cosmetology and pharmacy.

The invention discloses a method for preparing a super-hydrophobic antibacterial fabric with a photothermal effect. The method first loads a photothermal preparation on the surface of the fabric to impart photothermal properties, and then introduces a composite coating formed by hydrophobic silica nanoparticles and a silane coupling agent with an alkane chain to reduce the surface energy of the material and construct a micro-nanoscale rough structure, thereby preparing an antibacterial fabric with excellent photothermal and super-hydrophobic properties. The super-hydrophobic antibacterial fabric prepared by the invention has a fabric surface water contact angle of 158° and a surface temperature of 120°C under near-infrared light irradiation, showing excellent photothermal cycle stability and super-hydrophobic high temperature resistance. The super-hydrophobic antibacterial fabric has an antibacterial rate of over 99.0% under the synergistic effect of passive super-hydrophobic antibacterial adhesion and active photothermal sterilization, and has a wide antibacterial range and a long antibacterial life.

The invention belongs to the technical field of solar-driven interface evaporation, and particularly relates to a solar-driven interface evaporation aerogel material based on gradient modification and a preparation method and application thereof. The preparation method specifically comprises the following steps: performing cross-linking reaction on chitosan and a cross-linking agent in an organic acid aqueous solution, and performing freeze drying to obtain a chitosan matrix with a three-dimensional network structure; a pyrrole monomer is uniformly dispersed in a network structure of a chitosan matrix, then the chitosan matrix is immersed in an ammonium persulfate solution, and by controlling the oxidative polymerization degree of ammonium persulfate to the pyrrole monomer, concentration gradient distribution gradually decreasing from the surface to the inside of polypyrrole is formed in the chitosan matrix, so that the polypyrrole / chitosan composite material is obtained. The solar-driven interface evaporation aerogel material based on gradient modification is obtained. The aerogel material provided by the invention combines a photothermal effect with interface evaporation, and achieves the purpose of reasonably and efficiently utilizing solar energy resources to carry out seawater desalination.

The present invention pertains to the technical field of materials. Disclosed are a polymer composite hydrogel and a preparation method therefor, and a tooth desensitization material. The polymer composite hydrogel consists of a GelMA hydrogel and BP nanosheets composited inside the GelMA hydrogel, wherein the GelMA hydrogel is prepared by crosslinking gelatin methacryloyl via double bonds under the action of a photoinitiator. Under the photothermal effect, the polymer composite hydrogel of the present invention can enhance the resistance of dentin to external stimuli and promote the formation of stable and effective occlusion of dentinal tubules. Moreover, the occlusion effect on the dentinal tubules exhibits acid resistance, corrosion resistance, and stability, preventing the possibility of short-term reopening of the occluded dentinal tubules. This is of great significance for the treatment of occluded dentin hypersensitivity (DH).

The present invention belongs to the technical field of coating protection, and discloses a wear-resistant micro-nano structure super-hydrophobic coating with photothermal effect and a preparation method thereof. The method comprises the following steps: spin coating a defoamed PDMS prepolymer and a curing agent mixture onto a substrate for pre-curing treatment; adding micron carbon black particles or nano carbon black particles with photothermal effect into an organic solvent for ultrasonic dispersion to obtain a dispersion; spraying a micron carbon black dispersion on the surface of a substrate coated with PDMS, and then spraying a nano carbon black dispersion to obtain a coating with a micro-nano structure and a photothermal effect; then spraying a layer of PDMS prepolymer and a curing agent mixture diluted with an organic solvent on the surface, and curing at low temperature to enhance the wear resistance and mechanical stability of the coating. The coating prepared by the present invention has good super-hydrophobicity and wear resistance and durability; the photothermal effect significantly increases the temperature of the substrate under the action of sunlight, and has good application prospects in anti-icing.

The invention relates to a water treatment and membrane separation technology, and provides an integrated catalytic separation membrane, a preparation method thereof, and a water treatment method and system. According to the membrane, polyvinylidene fluoride is used as a continuous phase to form a porous matrix, and cerium dioxide is embedded and fixed in a mode of uniform dispersion in a membrane body in a phase inversion membrane forming process; in the presence of illumination and peroxysulfate, active species are generated through in-situ activation on a membrane-water interface, and membrane separation is completed synchronously. The water treatment method comprises the following steps: adding peroxymonosulfate or peroxydisulfate into a water body to be treated, and filtering through the membrane under illumination; the photothermal effect generated by organic matter degradation intermediates in operation inhibits membrane pollution and maintains flux. According to the invention, short-range coupling of active sites and mass transfer channels is realized, the medicament and energy utilization rate is improved, the coating stripping and metal dissolution risk is reduced, and the method is suitable for drinking water pretreatment, reclaimed water deep treatment and treatment of water containing natural organic matters / humic acid.

The invention relates to the technical field of preparation of surface micro-nano structures, and discloses a method for generating a micro-bulge structure based on a controllable gas phase microreactor, which comprises the following steps: preparing an organic mixed solution, mixing a driving solution methyl methacrylate into an initiator di-tert-butyl peroxide solution, then adding a solvent dimethyl sulfoxide solution, and stirring to obtain a mixed solution; meanwhile, ultrasonic oscillation is carried out for 10 minutes; according to the method for generating the micro-bulge structure based on the controllable gas-phase microreactor, the preparation of the micro-bulge structure can be realized only by directly dropwise adding a precursor organic mixed solution of a polymer on the surface of a substrate with a photothermal effect and then controlling the irradiation position and energy of continuous wave laser; compared with a photoetching method, the method has the advantages that complicated equipment operation and tedious process steps are not needed, and compared with the photoetching method, expensive photoetching machines, masks, vacuum chambers and complicated chemical reagent treatment processes are not needed, so that the operation flow is simplified.

The invention discloses a preparation method of photo-thermal-MMP dual-response matrix hydrogel and application of the photo-thermal-MMP dual-response matrix hydrogel in diabetic wound repair, and belongs to the technical field of biological medicine. According to the present invention, the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is composed of an amnion source photo-crosslinked matrix hydrogel, curcumin-loaded ZIF-8 nanoparticles and MMP2 peptide modified polydopamine, and the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is obtained; the ZIF-8 nanoparticles decline in an acid environment to release zinc ions, destroy bacterial cell membranes, enhance the permeability of a biological membrane and cooperatively kill drug-resistant bacteria in combination with a photothermal effect, Cur is loaded through ZIF-8 to form Cur-coated ZIF-8, then a Cur-coated ZIF-8-coated MMPDA / dAMG double-drug-loading system is constructed through an MMPDA medium, and a photothermal antibacterial, anti-inflammatory and regeneration-promoting multi-mode therapy is formed for a wound surface in the acid environment. Therefore, wound healing is accelerated.

The invention discloses a polydopamine modified and cupric peroxide loaded ZIF8 nano particle and application thereof, and belongs to the technical field of medicine preparation. According to the invention, a zeolite imidazoline framework 8 is used as a matrix, CuO2NPs is uniformly modified in the zeolite imidazoline framework 8 to form CuO2 (at) ZIF8NPs, and the surface of the CuO2 (at) ZIF8NPs is coated with a polydopamine film in the form of a film. The invention constructs multifunctional ZIF8NPs (CuO2 (at) ZIF8 (at) PDANPs) which is coated with PDA and loaded with CuO2NPs, and the multifunctional ZIF8NPs (CuO2 (at) ZIF8 (at) PDANPs is used for CDT of thermal enhancement OS. The CuO2 (at) ZIF8 (at) PDA NPs is combined with a photothermal effect and a chemodynamic therapy, shows good biocompatibility and an anti-tumor curative effect, has a potential application prospect in the aspect of osteosarcoma, and provides a new thought and method for treatment of osteosarcoma.

The invention relates to an anti-pollution ultrafiltration membrane based on a carbon nanotube photothermal effect, a preparation method of the anti-pollution ultrafiltration membrane and application of the anti-pollution ultrafiltration membrane in protein separation. The ultrafiltration membrane has a porous and loose structure, and is characterized in that high-dispersion carbon nanotubes are introduced, so that on one hand, the light absorption efficiency is improved by increasing light scattering and absorption paths, and on the other hand, heat transfer and accumulation in the membrane are promoted, and efficient temperature rise is realized. Under the illumination condition, the surface temperature of the ultrafiltration membrane is remarkably increased, denaturation of residual protein is promoted, denatured protein is effectively removed through a gas-liquid mixed flushing method, and flux recovery is achieved. The prepared ultrafiltration membrane has excellent anti-pollution performance and flux recovery rate, is suitable for the field of protein separation, and can remarkably prolong the service life and improve the separation efficiency of the membrane.

The invention provides a method for optimizing the photothermal effect of a graphene nano-coating of a photovoltaic panel, and belongs to the technical field of the graphene nano-coating of the photovoltaic panel, and the method comprises the steps: firstly, obtaining key parameters of the coating, including morphology, thickness, heat conductivity coefficient, absorbance and dispersity, carrying out multi-element mixing decomposition calculation, and separating a stable component from a variable component; then, constructing a positive and negative performance action equation set, and solving by using a Latin hypercube sampling method to obtain an analytical solution and a range solution; and based on the solutions, constructing through a game model, then adopting a genetic algorithm for multi-generation iterative optimization, and finally determining the optimal parameters of the graphene nano coating. And finally, accurately optimizing the coating according to the optimal parameters, and applying the coating to coating treatment of the photovoltaic panel. The method solves the problem that the prior art lacks an optimization method capable of comprehensively describing the coupling relation of all parameters in the photothermal conversion process of the graphene nano-coating and predicting the long-term performance change of the coating under severe conditions.