374 results about "Photothermal effect" patented technology

The invention provides a photo-thermal super-hydrophobic energy storage material, a preparation method thereof and application of the photo-thermal super-hydrophobic energy storage material in anti-icing and deicing, and belongs to the technical field of anti-icing and deicing. The photo-thermal super-hydrophobic energy storage material provided by the invention comprises an energy storage coating and a photo-thermal super-hydrophobic layer which are sequentially arranged from bottom to top, the energy storage coating comprises the following components: first resin and phase change energy storage microcapsules distributed in the first resin; the components of the photo-thermal super-hydrophobic layer comprise second resin and a photo-thermal inorganic material distributed in the second resin; the surface of the photo-thermal super-hydrophobic layer is provided with a micro-nano structure. Efficient anti-icing / deicing is achieved through the synergistic effect of the photothermal effect, the energy storage characteristic and the super-hydrophobicity, and the result of the embodiment shows that the anti-icing duration of the coating prepared through the method reaches 1.5 times that of a traditional super-hydrophobic surface. Meanwhile, under the illumination condition, the temperature of the coating can be increased to about 50 DEG C within 2000 s, and ice can rapidly fall off from the surface of the coating.

The invention relates to the technical field of preparation of composite functional materials, in particular to a scale structure coating based on a PDMS / Co (at) SiO2 composite material and a preparation method and application of the scale structure coating. The preparation method comprises the following steps: mixing vinyl-terminated polydimethylsiloxane with methylhydrosiloxane to obtain a pre-polymerized solution; dispersing cobalt powder in the prepolymerization liquid to obtain a PDMS / Co mixture, coating the PDMS / Co mixture on the surface of a mold with a scale structure, and stripping the mold after curing to obtain a PDMS / Co scale array; and modifying SiO2 nanoparticles on the surface of the PDMS / Co scale array to obtain the scale structure coating based on the PDMS / Co coated SiO2 composite material. According to the invention, by constructing the multistage micro-nano structure and cooperating with the magnetic response and photothermal effect, a ''magnetostrictive unbalance-elastic rebound'' liquid drop directional transport mechanism and a photothermal-super-hydrophobic cooperative anti-icing function are constructed, and the problems of low energy efficiency, poor environmental adaptability and easy failure under extreme conditions of an existing anti-icing material are solved.

The invention discloses a method for preparing a super-hydrophobic antibacterial fabric with a photothermal effect. The method first loads a photothermal preparation on the surface of the fabric to impart photothermal properties, and then introduces a composite coating formed by hydrophobic silica nanoparticles and a silane coupling agent with an alkane chain to reduce the surface energy of the material and construct a micro-nanoscale rough structure, thereby preparing an antibacterial fabric with excellent photothermal and super-hydrophobic properties. The super-hydrophobic antibacterial fabric prepared by the invention has a fabric surface water contact angle of 158° and a surface temperature of 120°C under near-infrared light irradiation, showing excellent photothermal cycle stability and super-hydrophobic high temperature resistance. The super-hydrophobic antibacterial fabric has an antibacterial rate of over 99.0% under the synergistic effect of passive super-hydrophobic antibacterial adhesion and active photothermal sterilization, and has a wide antibacterial range and a long antibacterial life.

The invention belongs to the technical field of solar-driven interface evaporation, and particularly relates to a solar-driven interface evaporation aerogel material based on gradient modification and a preparation method and application thereof. The preparation method specifically comprises the following steps: performing cross-linking reaction on chitosan and a cross-linking agent in an organic acid aqueous solution, and performing freeze drying to obtain a chitosan matrix with a three-dimensional network structure; a pyrrole monomer is uniformly dispersed in a network structure of a chitosan matrix, then the chitosan matrix is immersed in an ammonium persulfate solution, and by controlling the oxidative polymerization degree of ammonium persulfate to the pyrrole monomer, concentration gradient distribution gradually decreasing from the surface to the inside of polypyrrole is formed in the chitosan matrix, so that the polypyrrole / chitosan composite material is obtained. The solar-driven interface evaporation aerogel material based on gradient modification is obtained. The aerogel material provided by the invention combines a photothermal effect with interface evaporation, and achieves the purpose of reasonably and efficiently utilizing solar energy resources to carry out seawater desalination.

The present invention pertains to the technical field of materials. Disclosed are a polymer composite hydrogel and a preparation method therefor, and a tooth desensitization material. The polymer composite hydrogel consists of a GelMA hydrogel and BP nanosheets composited inside the GelMA hydrogel, wherein the GelMA hydrogel is prepared by crosslinking gelatin methacryloyl via double bonds under the action of a photoinitiator. Under the photothermal effect, the polymer composite hydrogel of the present invention can enhance the resistance of dentin to external stimuli and promote the formation of stable and effective occlusion of dentinal tubules. Moreover, the occlusion effect on the dentinal tubules exhibits acid resistance, corrosion resistance, and stability, preventing the possibility of short-term reopening of the occluded dentinal tubules. This is of great significance for the treatment of occluded dentin hypersensitivity (DH).

The invention relates to a water treatment and membrane separation technology, and provides an integrated catalytic separation membrane, a preparation method thereof, and a water treatment method and system. According to the membrane, polyvinylidene fluoride is used as a continuous phase to form a porous matrix, and cerium dioxide is embedded and fixed in a mode of uniform dispersion in a membrane body in a phase inversion membrane forming process; in the presence of illumination and peroxysulfate, active species are generated through in-situ activation on a membrane-water interface, and membrane separation is completed synchronously. The water treatment method comprises the following steps: adding peroxymonosulfate or peroxydisulfate into a water body to be treated, and filtering through the membrane under illumination; the photothermal effect generated by organic matter degradation intermediates in operation inhibits membrane pollution and maintains flux. According to the invention, short-range coupling of active sites and mass transfer channels is realized, the medicament and energy utilization rate is improved, the coating stripping and metal dissolution risk is reduced, and the method is suitable for drinking water pretreatment, reclaimed water deep treatment and treatment of water containing natural organic matters / humic acid.

The invention discloses a preparation method of photo-thermal-MMP dual-response matrix hydrogel and application of the photo-thermal-MMP dual-response matrix hydrogel in diabetic wound repair, and belongs to the technical field of biological medicine. According to the present invention, the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is composed of an amnion source photo-crosslinked matrix hydrogel, curcumin-loaded ZIF-8 nanoparticles and MMP2 peptide modified polydopamine, and the Cur (at) ZIF-8 (at) MMPDA / dAMG composite hydrogel is obtained; the ZIF-8 nanoparticles decline in an acid environment to release zinc ions, destroy bacterial cell membranes, enhance the permeability of a biological membrane and cooperatively kill drug-resistant bacteria in combination with a photothermal effect, Cur is loaded through ZIF-8 to form Cur-coated ZIF-8, then a Cur-coated ZIF-8-coated MMPDA / dAMG double-drug-loading system is constructed through an MMPDA medium, and a photothermal antibacterial, anti-inflammatory and regeneration-promoting multi-mode therapy is formed for a wound surface in the acid environment. Therefore, wound healing is accelerated.

The invention discloses a real-time operation optimization method and system for a multi-energy complementary electrolytic hydrogen production system, and the method comprises the steps: collecting real-time parameters of each module of the system, and inputting structured process knowledge to guide a neural network to predict a parameter change trend; based on a prediction result, constructing an optimization main model by using a distributed robust opportunity constraint programming algorithm, decomposing sub-models through a multi-main-body collaborative optimization algorithm based on ADMM, and solving the sub-models to obtain preliminary optimization parameters; and the photothermal effect is combined to induce the water phase regulation and control platform to regulate the medium state and the system operation parameters, closed-loop regulation is formed, and the final optimization parameters are output after the parameter deviation reaches the standard through iteration. The system comprises a multi-parameter collaborative acquisition unit, a structured knowledge driven prediction unit, a distributed robust optimization modeling unit, a multi-subject collaborative solving unit, a closed-loop parameter adjustment unit and an iterative optimization output unit, and all the units collaboratively realize real-time optimization of the system, so that the operation stability and economy are improved.

The invention belongs to the field of biological medicine and material science, and particularly relates to an intelligent response type piezoelectric nanofiber dressing and a preparation method and application thereof. According to the preparation method, polyvinylidene fluoride-trifluoroethylene, a high polymer material and inorganic nanoparticles are blended and spun through an electrostatic spinning technology, and then a photo-thermal component coating is subjected to surface in-situ oxidation and self-polymerization, so that the composite fiber membrane is prepared. Under the stimulation of ultrasound (US) and near-infrared laser (Laser), the fiber membrane can cooperatively activate the piezoelectric effect and the photothermal effect, generate a dynamic electric field and local high temperature, realize multi-mode cooperative killing of bacteria (the antibacterial rate exceeds 99%), and simulate an endogenous electric field to promote cell migration and wound healing. The dressing has good mechanical properties (the Young modulus is 15-20 MPa), hydrophilicity (the contact angle is about 30 degrees), biocompatibility and stability, is suitable for treatment of chronic infected wounds such as diabetes mellitus and the like, and has the advantages of on-demand activation and intelligent response.

Disclosed is a biomimetic nano-delivery system, comprising an inner core formed from a black phosphorus nanosheet and a drug, and a shell formed from an M1-type macrophage membrane. The biomimetic nano-delivery system has an anti-tumor effect, has a good photothermal effect under the irradiation of a near-infrared laser, and can actively recognize tumor cells and release the drug precisely and efficiently.

The invention discloses a control method for robot-assisted laser in-situ windowing, which comprises the following steps: receiving an execution instruction sent by a main control end through a robot catheter system, sending a laser fiber into a target artery, and enabling the laser fiber to be in accurate contact with a stent covering film; a laser energy closed-loop control subsystem is combined to accurately ablate holes in a stent covering film through a photochemical effect and a photothermal effect, and laser windowing is achieved; in the laser windowing process, the thickness of the blood vessel wall is measured in real time based on optical coherence tomography, and the laser ablation process is detected based on photoacoustic monitoring, so that the laser power is dynamically adjusted, and it is ensured that the thermal damage range in the laser windowing process is smaller than 200 microns. Therefore, accurate creation of the channel between the aortic dissection false cavity and the true cavity is achieved, hemodynamic balance is recovered, the operation accuracy is improved, and the risk of complications in the perioperative period is reduced.

The invention discloses an integrated nano platform for bimodal detection and synergistic sterilization of pathogenic bacteria as well as a preparation method and application of the integrated nano platform, and belongs to the technical field of food safety. The platform is composed of a multifunctional nano probe (MPDA / Pd SA-DA-CDs / Apt) and a magnetic separation assembly (MNRs / PGA / AM). The probe integrates enzyme-like catalysis and photo-thermal performance and is used for generating colorimetric and photo-thermal dual-mode signals so as to realize high-sensitivity and high-reliability detection of pathogenic bacteria. The magnetic separation assembly is used for specifically capturing and enriching target bacteria and eliminating matrix interference. After detection is positive, the platform can immediately start secondary propulsion synergistic sterilization: firstly, the action distance is shortened through magnetic aggregation, and then pathogenic bacteria are efficiently inactivated and biological membranes are disintegrated by utilizing the synergistic effect of near-infrared laser excitation photothermal effect and active oxygen. According to the invention, the integration of detection and disinfection is realized, the operation is convenient, and the method has important application value in the fields of food safety and biomedicine.

The invention belongs to the technical field of biological medicine, and particularly relates to a copper sulfide-gold nano-cluster composite liposome and a preparation method and application thereof, and the copper sulfide-gold nano-cluster composite liposome is composed of copper sulfide nanoparticles, gold nano-clusters and liposome; the preparation method comprises the following steps: loading a gold nano-cluster on the surface of a copper sulfide nano-particle, and then coating the copper sulfide nano-particle with a 1, 2-distearoyl-sn-glycerol-3-phosphorylethanolamine-L-lysine-2, 3-dimethyl maleic anhydride liposome with pH response, so as to obtain the copper sulfide-gold nano-cluster composite liposome. According to the copper sulfide-gold nano-cluster composite liposome prepared based on the method, a biofilm matrix of MRSA can be disintegrated through a photothermal effect, permeation of nanoparticles and ROS is enhanced, and the problem that traditional antibiotics are ineffective to biofilms is solved.

The utility model discloses a blue-green algae mud dehydration treatment device based on a solar photothermal conversion technology, which belongs to the technical field of blue-green algae dehydration and comprises a dehydration chamber, an evaporation chamber, a collection chamber, a water storage chamber and a photovoltaic power supply system which are communicated in sequence, the dehydration chamber is located below the treatment device, the outer side of the dehydration chamber is connected with an algae mud branch pipe, and an evaporation system is arranged in the dehydration chamber and comprises an underwater heat conduction shell and a floating type composite fabric material; the evaporation chamber is positioned above the whole device; a water collecting top plate is arranged in the evaporation chamber; the floating type composite fabric material is a carbon fiber fabric modified by a nitrogen-doped carbon nano tube; the collecting chamber is positioned on one side of the evaporation chamber; and the water storage chamber is positioned below the collecting chamber. Solar energy is used as clean energy, moisture in blue-green algae is evaporated through the photothermal effect, and therefore efficient treatment of the blue-green algae is achieved, environmental pollution caused by chemical treatment can be reduced, and economic cost of blue-green algae treatment can be effectively reduced.

The invention discloses a photo-thermal composite desalination membrane with an enhanced MOF (Metal Organic Framework) heat insulation layer and a preparation method. The membrane comprises a porous support layer, an NH2-UiO-66 heat insulation middle layer and a PVA-GO photo-thermal separation layer, wherein the NH2-UiO-66 heat insulation middle layer grows on the surface of the porous support layer in situ; and the PVA-GO photo-thermal separation layer is sprayed on the surface of the heat insulation middle layer and is subjected to photo-thermal induced crosslinking. The preparation method comprises the following steps: firstly, successfully growing an NH2-UiO-66 nano heat insulation layer with a uniform granular structure on the surface of a SE / PMIA membrane by an in-situ growth method, then successfully spraying a PVA-GO solution to the surface of the NH2-UiO-66 (at) SE / PMIA membrane by a spraying method, and successfully preparing the photo-thermal composite desalination membrane PVA-GO (at) NH2-UiO-66 (at) SE / PMIA by utilizing a photo-thermal effect. According to the photo-thermal composite desalination membrane, on the basis of realizing efficient photo-thermal conversion to drive cross-linking of the separation layer, the permeability and the separation performance are further improved, and the membrane has excellent performance in actual seawater desalination treatment.

The invention discloses an S-type three-dimensional carbon nitride / copper sulfide nanosphere heterojunction as well as a preparation method and application thereof, and belongs to the field of antibacterial application of nano materials. The three-dimensional porous carbon nitride not only can increase photocatalytic active sites, but also can improve close contact with copper sulfide. The copper sulfide nanospheres and the three-dimensional porous nanosheets construct an S-shaped heterojunction, and efficient separation of photo-induced electrons and hole pairs can be driven under the action of a built-in electric field, band edge bending and coulomb force. The S-type three-dimensional carbon nitride / copper sulfide nanosphere heterojunction can generate more active oxygen species to inactivate bacteria through a photocatalysis-Fenton-like reaction; in addition, the photothermal effect of copper sulphide has a certain auxiliary sterilization effect. Under the conditions of visible light irradiation and trace hydrogen peroxide, the inactivation rates of the S-type three-dimensional carbon nitride / copper sulfide nanosphere heterojunction on staphylococcus aureus and escherichia coli are up to 99.5% and 99.7% respectively, and meanwhile, the S-type three-dimensional carbon nitride / copper sulfide nanosphere heterojunction has a remarkable treatment effect on wounds infected by staphylococcus aureus.

The present application relates to the technical field of targeted cargo delivery, and more particularly to a drug loading and delivery method and a cell carrying method of core-shell mesoporous micro-nanorobot. The drug loading and delivery method is realized based on the drug loading capacity of the mesoporous structure, the magnetism of the iron oxide core and the photothermal effect of the polydopamine shell. The core-shell mesoporous micro-nanorobot can adsorb and load drugs through the capillary force and electrostatic force generated by the mesoporous structure; then the movement of the core-shell mesoporous micro-nanorobot is driven by an external magnetic field; when the core-shell mesoporous micro-nanorobot approaches the target area, the pore structure is irradiated by near-infrared light, the temperature of the pore structure is increased and the thermal vibration is accompanied, the drugs in the mesoporous structure are effectively released to the target area, and the drug delivery effect is achieved. At the same time of drug loading and delivery, the core-shell mesoporous micro-nanorobot has a carrying capacity after clustering under the magnetic field, and carries cells through two methods of eddy current carrying and contact adhesion. The targeted cargo delivery of targeted drugs and cells and other cargos can be realized by the micro-nanorobot.

The invention relates to a hydrogel light-operated multi-mode synergistic treatment platform based on a CuxS-MoS2 heterojunction for promoting wound healing of diabetes mellitus. And an interface induced electric field strategy is provided through density functional theory (DFT) calculation to optimize the charge migration behavior of the phototherapy agent. The multifunctional phototherapy system is constructed by taking CuxS-MoS2 with a built-in electric field as a core and PVA-CS hydrogel loaded with glucose oxidase (GOx) as a bracket. In a weakly acidic wound microenvironment, glucose at the wound is catalyzed by GOx to be converted into H2O2 and gluconic acid; meanwhile, the CuxS-MoS2 remarkably enhances the generation of reactive oxygen species (ROS) under illumination through peroxidase-like (POD) activity, photothermal effect (PTT) and heterojunction efficient carrier separation. After entering a proliferation period, the stent exerts catalase-like (CAT) activity to remove excessive ROS and release oxygen, and oxygen deficit and oxidative stress are relieved. In addition, the controllably released copper ions regulate and control the behavior of fibroblasts, promote healing and inhibit fibrosis. Experiments prove that the stent has excellent biocompatibility, effective antibacterial property and remarkable healing promoting effect in chronic wound repair of diabetes mellitus.

The invention relates to the technical field of photo-thermal control, and provides a distributed photo-thermal correction method and system for an MIP LED display screen. Deploying sensors on the surface of the display screen, and constructing a sensor network among the sensors to collect photo-thermal data of the display screen; performing model construction based on the photo-thermal data and the material parameters of the display screen, and generating a first model representing light attenuation and a second model representing heat conduction; coupling the first model and the second model to generate a photo-thermal coupling model; performing optimization driving on each LED through the photo-thermal coupling model and preset target bright color parameters to generate driving parameters; and distributing the driving parameters to a control unit of the LED so as to control the operation of the LED. The photothermal effect can be accurately simulated through model construction and coupling, so that the LEDs are optimally driven, driving parameters are generated, and then operation is distributed and controlled, the accuracy of display correction is improved, and the stability and uniformity of the display effect of the display screen are enhanced.

The present application discloses an antibacterial hydrogel dressing with integrated constant temperature photothermal effect and controlled drug release function, as well as its preparation method and application, which belongs to the field of medical biomaterial technology. The antibacterial hydrogel dressing with integrated constant temperature photothermal effect and controlled drug release function provided by the present application includes: a dressing and an antibiotic drug compounded on the dressing; the dressing is woven from photothermal water gel fiber and thermosensitive hydrogel fiber; the photothermal water gel fiber is made of photothermal dye, proton donor and phase change material as the core layer and sodium alginate as the shell layer; the thermosensitive hydrogel fiber is made of N-isopropyl acrylamide, methylene bisacrylamide, phenyl-2,4,6-trimethylbenzoyl lithium phosphinate and sodium alginate. The hydrogel dressing prepared by the present application has an inherent temperature control mechanism, can release drugs on demand and in a concentrated manner, has excellent antibacterial effect, and has broad application prospects in the preparation of biomedical materials.

The invention discloses a photo-thermal catalyst for converting waste starch plastic into amylose as well as a preparation method and application of the photo-thermal catalyst. The photo-thermal catalyst mainly comprises a halogen-containing thermal catalyst capable of playing a role at a certain temperature and a photo-thermal conversion agent capable of playing a photo-thermal conversion role under illumination; the invention mainly relates to a confined halogen-containing thermal catalyst, a halogen-modified thermal catalyst, a non-confined halogen-containing thermal catalyst, a modified halogen-containing thermal catalyst and a photo-thermal conversion agent with a photo-thermal effect. The photo-thermal catalyst provided by the invention can convert more than 70% of amylopectin in starch into amylose, so that high-value amylose is recovered from waste starch plastic. The technology provided by the invention does not involve an organic solvent, a high temperature and an inert gas atmosphere, and the reaction product is simple and convenient to separate. The technology is suitable for recycling various waste starch plastics and mixed plastics of starch plastics and other plastics.

The invention discloses a water-soluble near-infrared two-region aggregation-induced emission material and a preparation method and application thereof, and belongs to the technical field of aggregation-induced emission materials.Benzobithiadiazole is used as an electron acceptor group, dithieno-cyclopentadiene and derivatives thereof are used as electron donor units, and benzobithiadiazole and dithieno-cyclopentadiene and derivatives thereof are coupled to form the water-soluble near-infrared two-region aggregation-induced emission material. The organic near-infrared second-region molecule with the intramolecular charge transfer characteristic is constructed. According to the invention, the positively charged quaternary ammonium salt group is introduced into the electron donor group, and the positively charged quaternary ammonium salt group has good hydrophilicity, so that the water solubility of molecules can be effectively improved. Moreover, the water-soluble near-infrared two-region aggregation-induced emission material has excellent photodynamic and photothermal activity, and realizes efficient killing of bacteria (especially propionibacterium acnes) through the synergistic effect of photodynamic and photothermal effects.

Apparatus and methods are described for treating an occlusion in a blood vessel. A catheter is inserted into the blood vessel. An irradiation unit is driven to emit probing radiation such that the probing radiation is directed toward the occlusion, and returning radiation which is returned in response to the probing radiation impacting the occlusion, is detected. A composition of at least a portion of the occlusion is derived based on a signature that is indicative of the composition within the returning radiation. The irradiation unit is driven to irradiate the portion of the occlusion by emitting treatment radiation having a set of irradiation parameters. The set of irradiation parameters is determined to modulate between a photoacoustic effect of the treatment radiation and a photothermal effect of the treatment radiation, based on the composition of the portion of the occlusion. Other applications are also described.

The invention discloses a photo-induced quantum dot in-situ growth method for coupling and filling element defects and application, relates to the technical field of optical element defect detection, and solves the problems of poor selectivity, low resolution and low sensitivity of a thermally induced in-situ growth material in defect detection of an optical element in the prior art. According to the invention, the CsPbBr3 quantum dot precursor is selectively filled in the defect area on the surface of the element, and the CsPbBr3 quantum dot precursor is induced to grow in situ at the defect position under the irradiation of a specific light source, so that a remarkable local photothermal effect is generated at the defect position. According to the method, the problem that a traditional thermal induction method is insufficient in positioning selectivity in a defect area is effectively solved by utilizing a selective growth mechanism, high-sensitivity, high-selectivity and high-spatial-resolution positioning detection on microdefects of the optical element can be realized, and the method can be applied to defect positioning of the optical element; and a new technical approach is provided for visual characterization and high-precision positioning of defects.

This invention discloses a material with high photothermal conversion efficiency, its preparation method, and its application in neural modulation, belonging to the field of biomedical technology. In this method, liquid metal is ultrasonically spun into nanoscale particles. Using these liquid metal nanoparticles as templates, hollow nanoshells composed of ultra-small metal nanoparticles can be prepared through an electrocoupling reaction with a metal salt. This method is simple, easy to operate, and applicable to various metals. The prepared material with high photothermal conversion efficiency has a hollow structure, a rough surface, and pores. This unique structure endows it with a strong photon trapping ability, significantly enhancing light absorption and exhibiting ultra-high photothermal conversion efficiency. This invention allows for the injection of this material into the nerve, utilizing its excellent photothermal effect for rapid and precise neural modulation, thereby achieving effective prevention and treatment of autonomic nervous system-related diseases, and showing promising application prospects.

The invention discloses an anti-tumor bacterium medicine based on engineered Serratia marcescens and a preparation method of the anti-tumor bacterium medicine based on engineered Serratia marcescens. According to the anti-tumor bacterium medicine disclosed by the invention, attenuated Serratia marcescens is taken as a carrier, is encapsulated and then is coupled with a targeting peptide, and then is delivered into tumor tissues to play an anti-tumor role; the attenuated Serratia marcescens is subjected to metabolism to generate the prodigiosin, and the attenuated Serratia marcescens is subjected to metabolism to generate the prodigiosin; the anti-tumor bacterium drug is combined with near-infrared laser irradiation to realize an anti-tumor effect. Biosynthesis of a photosensitive natural product prodigiosin is combined with bacterial treatment, and the near infrared (NIR-II) photosensitivity and photothermal effect of the prodigiosin are innovatively utilized, so that the anti-tumor effect is enhanced, precise bacterial removal after treatment is realized, and a feasible solution is provided for clinical application of bacterial treatment.

The present application is applicable to the field of material technology, and provides a hollow nanocomposite material and its preparation method and application. The structural formula of the hollow nanocomposite material is Au NBPs@CuS, wherein CuS is an outer semiconductor and Au NBPs is an inner core. The present application is a nanostructure with a gold nanobipyramid as the inner core and a hollow p-type semiconductor as the outer layer, which realizes the first combination of p-type semiconductor and gold nanobipyramid. The tip effect of Au NBPs is better than that of previous Au NPs, and its ultraviolet absorption reaches a maximum at 808nm, and its phototherapy performance is greatly improved. By compounding Au NBPs with CuS, not only its photothermal performance is greatly improved, the photothermal conversion efficiency reaches 43.88%, and it can generate active oxygen under light. 1 O2 and ·OH, their excellent photothermal effect and photodynamic properties provide theoretical support for their application in inhibiting amyloid protein aggregation.

The invention discloses a non-contact handwriting device based on an ultraviolet specific image sensor and a preparation method, and relates to the technical field of image sensing and human-computer interaction. Comprising a glass substrate 1, a transparent thin film transistor array 2 formed on the substrate, a photosensitive material layer 3 formed on the thin film transistor array, and an ultraviolet curing adhesive packaging layer 4 covering the photosensitive material layer. A light-sensitive material is a Bi2S3 material with a wavelength selective light current memory characteristic, generates long-time light current maintenance based on a photo-thermal electric effect in an ultraviolet band, rapidly attenuates in visible to near-infrared bands, and has ultraviolet input selectivity and ambient light anti-interference capability. According to the system, an ultraviolet laser pen is used as an input tool, handwriting patterns which can be kept for a long time are formed on an image sensor array, and image erasing based on a background normalization mechanism is supported. The image sensor array is composed of synaptic-like devices, has a long-term optical memory characteristic, and realizes integration of perception and storage.

Systems and methods for sensing vibrational absorption induced photothermal effect via a visible light source. A Mid-infrared photothermal probe (MI-PTP, or MIP) approach achieves 10 mM detection sensitivity and sub-micron lateral spatial resolution. Such performance exceeds the diffraction limit of infrared microscopy and allows label-free three-dimensional chemical imaging of live cells and organisms. Distributions of endogenous lipid and exogenous drug inside single cells can be visualized. MIP imaging technology may enable applications from monitoring metabolic activities to high-resolution mapping of drug molecules in living systems, which are beyond the reach of current infrared microscopy.

The application belongs to the technical field of targeted drugs, and discloses a carrier, a targeted nanoparticle and a preparation method and application thereof. The carrier disclosed by the application comprises darpin grafted with a dye containing a terminal carboxyl group. The targeted nanoparticle comprises the carrier and a CO releasing molecule, and the carrier coats the CO releasing molecule to form a core-shell structure. The targeted nanoparticle is based on darpin, the grafting of the dye containing the terminal carboxyl group is performed to construct the carrier, and then the carrier coats the CO releasing molecule, wherein the carrier has a targeting effect, and the photothermal effect of the carrier can realize the NIR laser controlled CO releasing or free radical stimulation, and can also target the controllable CO releasing, so that the double response releasing of exogenous CO and endogenous CO is realized, and the application has a wide application prospect.