4results about How to "Suitable for storage" patented technology

The invention belongs to the field of medicine preparation, and particularly relates to a nano delivery carrier of IL-22BPmRNA (Interleukin-22BPmRNA). The invention aims to overcome the defect of less types of ionizable phospholipids for preparing LNP delivery mRNA. The technical scheme for solving the technical problem is to provide a nano delivery carrier of IL-22BPmRNA, which is prepared on the basis of a novel ionizable phospholipid molecule capable of being used for preparing a nucleic acid delivery carrier. The nano delivery carrier of the IL-22BPmRNA, disclosed by the invention, is good in stability. Experiments show that therapeutic RNA can be efficiently delivered to various human and mouse tumor cells, high-level protein expression is realized, and the polypeptide has unique advantages and good application prospects in the field.

The present application relates to compressed gas energy storage technology field, specifically to a kind of subcritical water compressed gas energy storage system and control method thereof.Energy storage system includes: gas storage device, energy storage pipeline, energy release pipeline, compression component, expansion component, cold storage tank, heat storage tank, supercooling pipeline, first heat exchanger, first pressure regulating component etc., first pressure regulating component is directly or indirectly communicated with the cold storage tank.The subcritical water compressed gas energy storage system provided by the present application sets first pressure regulating component, so that the water pressure of cold subcritical water in supercooling pipeline can be adjusted in real time, so that cold subcritical water can be in the best pressure state at any temperature, improve the heat exchange efficiency of compressed gas energy storage system using subcritical water as heat exchange medium.At the same time, through the control method of system, the pressure of subcritical water in heat exchange process of heat storage system can be automatically selected according to the temperature of compressed air at the outlet of compression component, realize the efficient and stable operation of compressed air energy storage power station heat storage system.

This invention belongs to the field of traditional Chinese medicine nano-oral preparations, and provides a traditional Chinese medicine composition for the prevention and treatment of cardiovascular and cerebrovascular diseases and its preparation method. This invention uses a core-shell type nanocomposite dry powder design of Panax notoginseng total saponins core and Astragalus polysaccharide shell, combined with ethanol water dispersion, pH control, high pressure homogenization and spray drying, to form an oral solid system with controlled particle size and dispersibility after reconstitution. It achieves a balance between reconstitution stability, gastrointestinal release regulation, storage stability and oral utilization, and solves the problem of mutual restraint between nanoparticle reconstitution dispersion and release regulation. It is applicable to oral traditional Chinese medicine preparations related to the prevention and treatment of cardiovascular and cerebrovascular diseases.

The application provides an automatic feeding and core removing device and a use method, relates to the technical field of core removing, and comprises an automatic screening and feeding mechanism, a clamping and blocking mechanism, a clamping mechanism, a pulling mechanism, a moving mechanism and a rack. The automatic screening and feeding mechanism is installed on one side of the rack and is used for automatically screening and feeding fishing rod materials. The rear end of the automatic screening and feeding mechanism is provided with a fishing rod collecting groove. The clamping and blocking mechanism, the clamping mechanism, the pulling mechanism and the moving mechanism are all fixedly installed on the rack, and the rear end of the rack is provided with a core pipe collecting groove. The device can realize automatic feeding, pulling and core removing, and separation and output, has the advantages of high automation degree, simple operation, greatly reduced labor intensity, saved labor cost, high adaptability and high production efficiency.