The application provides a sand-proof throttling well killing manifold, and relates to the technical field of oil exploitation.The sand-proof throttling well killing manifold comprises a first pipeline and a second pipeline, a throttling valve is arranged on the second pipeline, a sand-proof cylinder is arranged between the first pipeline and the second pipeline, a first opening is arranged on one side of the sand-proof cylinder, a second opening is arranged on the other side of the sand-proof cylinder, an upper sealing plate and a lower sealing plate are arranged in the sand-proof cylinder, a communication cavity is formed between the upper sealing plate and the lower sealing plate, a rotating shell is rotatably arranged in the communication cavity, mounting holes are symmetrically arranged on the left side and the right side of the rotating shell, filter screens are arranged in the mounting holes, a driving mechanism is arranged in the sand-proof cylinder, and the driving mechanism is used for driving the rotating shell to rotate in the communication cavity.In the application, the rotating shell is driven to rotate in the communication cavity by the driving mechanism, the filter screens are driven to rotate by the rotating shell, when the filter screens pass through the sand-proof cylinder, the fine sand particles on the surface of the filter screens can be scraped off by the inner wall of the sand-proof cylinder, the filter screens are prevented from being blocked, the cleaning process does not need to stop working, and the continuity of the throttling well killing manifold operation is ensured.