9 results about "Cervicitis" patented technology

The invention patent is titled "Dragon and Cypress Gel," belonging to the pharmaceutical category. The main components of Dragon and Cypress Gel are: Phellodendron bark, earthworm, dragon's blood, Oldenlandia diffusa, Sophora flavescens, and Bletilla striata. In recent years, research on cervicitis and cervical lesions has shown good results using external treatments of traditional Chinese medicine. Vaginal cervical medications are characterized by high local drug concentration, low dosage, and safety and effectiveness, receiving high clinical evaluation. The vagina and cervix have abundant capillaries and lymphatic vessels, and lack clearly defined nerve endings, resulting in minimal pain stimulation for patients during administration. This makes it an effective drug release site for specific diseases such as cervicitis and vaginitis. Traditional Chinese medicine gels are a novel type of external preparation of traditional Chinese medicine. They are made by dissolving or uniformly dispersing traditional Chinese medicine in a gel. These gels adhere tightly to the treatment site for a relatively long time, exhibiting good bioadhesion, and are simple to prepare. It is suitable for use on skin, mucous membranes and cavities. It not only avoids the first-pass effect of enzymes and acids in the gastrointestinal tract that exists in oral administration, but also reduces the adverse reactions of drugs. It has the characteristics of good spreadability, non-greasy feeling, easy to wash off, good transdermal absorption, and comfortable use.

The invention discloses skin mucosa maintenance liquid capable of killing fungi and HPV (human papillomavirus) as well as a preparation method and application of the skin mucosa maintenance liquid, and belongs to the technical field of sterilization and virus removal. The skin mucosa maintenance liquid is prepared from octanol ether, benzalkonium bromide, phenoxyethanol, yermate, parachlorometaxylenol, taetinic acid, chitosan, keratinase, fluconazole, glycerol, borneol, menthol, absolute ethyl alcohol and tween-40. Wherein the skin mucosa maintenance liquid has an effect of regulating apoptosis induction on abnormal cells and an effect on vaginal flora, and has an obvious inhibition effect on cervicitis and colpitis mycotica, namely an anti-inflammatory effect; meanwhile, apoptosis of cells containing HPV16 and HPV18 genes can be induced, shedding of abnormal cells is promoted, diseased cells are killed, and vaginal tissues with pathological changes are removed.

The present application relates to Dendrobium officinale flower extract, in particular to a Dendrobium officinale flower active part in the preparation of a drug for treating cervicitis; a Dendrobium officinale flower active part in the preparation of a drug for treating cervicitis; characterized in that the Dendrobium officinale flower active part is prepared by the following steps: weighing 4g of Dendrobium officinale flower, adding 200mL of purified water, boiling water bath for 1h, extracting 3 times, then filtering and combining the filtrate, removing most of the water, and then water bath evaporation; the extract is added with 100mL of purified water to prepare a suspension, extracted with ethyl acetate, and extracted 3 to 4 times until complete extraction; the concentrated extract is the ethyl acetate part DOF- EA of the Dendrobium officinale flower boiling water extract. The present application adopts a mouse cervicitis model induced by phenol glue, and DOF- EA is administered by gavage, and the results show that DOF- EA can significantly improve the damage of cervical mucosa tissue, reduce the level of inflammatory factors and oxidative stress, and has a good effect on anti-cervicitis.

The invention relates to a capsule for treating gynecological diseases and a preparation method thereof. The capsule is prepared from polygonum cuspidatum, sargentgloryvine stem, coptis chinensis, rhizoma bletillae, radix gentianae, dragon's blood, cuttlebone, rheum officinale, aloe, catechu, astragalus membranaceus, chloramphenicol and purified water. The capsule is prepared through a powder preparation process, a conventional vaginal medicine filling method is adopted for administration, the capsule is dissolved by virtue of vaginal secretion to release medicine, and the medicine acts on the vagina, the cervix uteri and the endometrium and directly reaches a focus, so that the effects of diminishing inflammation, sterilizing, resisting viruses, diminishing swelling, removing stasis and repairing mucosa are achieved; the traditional Chinese medicine composition can be used for treating colpitis mycotica, infectious microbe vaginitis, cervical erosion, cervicitis, HPV infection and endometritis. The capsule is a proved recipe inherited by several generations, has a good curative effect, takes traditional Chinese medicines as main raw materials, is added with a small amount of western medicines, has the advantages of benefiting and eliminating disadvantages, has no side effect, no preservative and no irritation, has an effective rate of 99% and a cure rate of 98%, and is worthy of popularization.

The invention discloses a method for detecting effective components of a cervicitis treatment composition, which adopts high performance liquid chromatography for detection, and the chromatographic conditions are as follows: a chromatographic column is a C18 chromatographic column; the detection wavelength is 207 nm; a mobile phase A is a 0.2% phosphoric acid aqueous solution, a mobile phase B is acetonitrile, gradient elution is adopted, the mobile phase proportion is volume percent, and the elution procedure is as follows: 0-5 min, the mobile phase A is 100%, and the mobile phase B is 0%; the mobile phase A accounts for 100%-96% and the mobile phase B accounts for 0%-4% in 5-40 min; 40-60 min, the mobile phase A is 88%-58%, and the mobile phase B is 12%-42%; the mobile phase A accounts for 92% and the mobile phase B accounts for 8% in 60-80 min. The method disclosed by the invention can be used for simultaneously determining the components such as sophocarpidine, sophoridine, oxymatrine and amygdalin in the cervicitis composition, is convenient to operate, accurate in detection result and good in stability, and has very high practicability.

The invention discloses a traditional Chinese medicine vaginal suppository for treating cervicitis diseases and a preparation method and application thereof, and relates to the field of traditional Chinese medicine preparations, the preparation method comprises the following steps: S1, mixing polygonum aviculare, radix rehmanniae, curcuma zedoary, pepper and croton, crushing and sieving to obtain traditional Chinese medicine powder; s2, dividing the traditional Chinese medicine powder into two parts, and blending to form quick-release layer medicine slurry and slow-release layer medicine slurry; s3, injecting the slow-release layer medicine slurry into a mold cavity, cooling and curing, injecting the quick-release layer medicine slurry into the outer layer of the mold cavity, and performing pressure treatment and cooling to obtain a molded suppository; and S4, wrapping the formed suppository with a disinfection material, and mooring a thread which can be taken out to obtain the traditional Chinese medicine vaginal suppository. The suppository disclosed by the invention can quickly exert anti-inflammatory and antibacterial effects, improve symptoms such as cervical erosion and abnormal leukorrheal and is beneficial to breaking the persistent circulation of cervicitis, so that both symptoms and root causes are treated, and disease relapse is reduced.

The invention belongs to the technical field of gynecological gel, and provides medical recombinant protein gynecological gel and a preparation method and application thereof.The medical recombinant protein gynecological gel is prepared from, by mass, 0.05%-0.3% of recombinant collagen, 0.01%-0.05% of recombinant fibronectin, 0.05%-0.3% of recombinant elastin, 0.1%-1% of isomaltooligosacharide, 0.01%-0.1% of sodium hyaluronate, 21%-26% of poloxamer 407, 0.03%-0.1% of lactic acid, 0.08%-0.2% of preservative and the balance water. And 2-8% of glycerol and the balance of purified water. The gel provided by the invention particularly has a good repairing effect on cervicitis, and is long in retention time, high in retention rate and not easy to flow out.

This invention discloses an improved cervicitis treatment composition and its preparation method, made from the following raw materials in parts by weight: 13-20 parts of Sophora flavescens, 0.3-0.8 parts of alum, 0.4-0.8 parts of bitter almond, and 0.02-0.04 parts of borneol. The improved cervicitis treatment composition of this invention has been formulated by adjusting the proportions of Sophora flavescens, alum, and bitter almond. While maintaining its basic efficacy, the dosage of the drugs has been reduced, improving the therapeutic effect and resulting in better economic value.

The invention discloses an application of pulsatilla saponin B5 with a structure shown as a formula I in preparation of a medicine for vaginitis and / or cervicitis. The vaginitis is bacterial vaginitis, and the cervicitis is bacterial inflammation of the cervix and the vagina. The invention relates to a spray for vaginitis and / or cervicitis, in particular to bacterial vaginitis and / or bacterial cervix and vagina inflammation and application thereof. The spray is prepared from the following components in parts by weight: 0.5 to 5 parts of pulsatilla saponin B5, 0.05 to 1 part of sucralose, 0.01 to 0.05 part of benzalkonium chloride and 100 parts of water.