The invention discloses an administration method for an 
experimental animal brain; by adopting a method for burying a 
catheter into the 
experimental animal brain, injection to the 
experimental animal brain is more convenient. According to the administration method, a special successive administration device is adopted, and a mouse or a rat is taken as an experimental animal, and the administration method comprises the following steps: 1, narcotizing the experimental animal with 30 percent of 
chloral hydrate, fixing the experimental animal on a mouse brain locator, and determining the position of a paracele; 2, burying an administration 
catheter into the paracele of the experimental animal according to the step, and fixing the 
catheter to the head of the experimental animal by 
dental cement when 
cerebrospinal fluid overflows from the catheter; 3, in 4 days after the catheter is buried successfully, performing successive 
intramuscular injection every day with 0.2ml of 0.8 
million units of 
penicillin sodium, and diminishing 
inflammation of the experimental animal; 4, performing administration: sucking up a right amount of to-be-experimented 
drug solution by a 10mul microinjector, and partially inserting the 
syringe needle of a microsyringe into the catheter buried into the experimental 
animal brain, wherein the 
insertion depth is 0.5-2.0cm, and successive administration can be performed on the 
mice brain from the catheter.