65 results about "Gentamycin sulfate" patented technology

The invention belongs to the technical field of medicines and discloses a medicament for treating dental ulcer of infants. Gentamycin sulfate chewable tablets, prednisone acetate tablets, vitamin C tablets and vitamin B complex tablets (each tablet comprises main components of 13mg of vitamin B, 21.5mg of vitamin B, 60.2mg of vitamin B, 10mg of niacinamide and 1mg of dextro calcium pantothenate ) are used as raw materials, are mixed in the ratio according to different characteristics of each medicinal raw material, are dried at low temperature, ground, evenly blended and sterilized and subjected to other treatments and are prepared into western medicine powder or a spraying agent. The invention has the characteristics of new formula, simple manufacture and remarkable effect; and raw materials for preparing medicaments have wide source and low price, so the cost of medicinal products is reduced. Used by 120 infants suffered from infant dental ulcer, the total effective rate reaches 100 percent and special toxic and side effects are not found.

The invention provides an enzyme conjugate stabilizing solution which comprises the following components: 1-7.5g / L protein material, 5-50g / L saccharide material, 2-30g / L amino acid material, 5-50g / L antipyrine, 1-10 g / L vitamin C, 0.2-5g / L surfactant, 0.5-5 million IU / L gentamycin sulfate, 0.5g / L Proclin 300 and 0.02mol / L phosphate buffer solution the pH value of which is 7.4, wherein the protein material is bovine serum albumin or casein; the saccharide material is trehalose, gluecose, lactose or cane sugar; the amino acid material is glycine, phenylalanine, praline, tyrosine, serine, cysteine, methionine, glutamoyl or lysine; the surfactant is Twain-20, Twain-80 or triton x-100. The enzyme conjugate stabilizing solution provided by the invention solves the problem that the enzyme conjugate is easy to lose activity after the enzyme is not in the low temperature storage environment in related technology.

The related method for gentamycin sulfate detection standard curve comprises: coupling protein and gentamycin sulfate to inject into rat body and prepare antibody, selecting the work concentration for antigen and antibody reaction by chess board method, and selecting holes with OD450 value as 1-1.5 to calculate and draw the curve. The enzyme linked immunity fast detection method comprises: 1. diluting antibody, adding gradient-diluting sample, enzyme link reacting for 1-1.5h at 41Deg, developing with TMB; 2. selecting the sample with 0.4-1.5OD value; 3. checking data in curve, and multiplying dilution time to obtain the residual gentamycin sulfate. This detection method needs time only 1-1.5h.

The invention discloses a composition for treating infection of pseudomonas aeruginosa in chicken and a preparation method thereof, aiming to provide a composition for treating the infection of pseudomonas aeruginosa in chicken, which is capable of reducing the drug resistance rate of bacteria and addressing both the symptoms and root causes, and a preparation method thereof. The composition consists of the following components in percentage by weight: 4 to 12 percent of gentamycin sulfate, 4 to 8 percent of amoxicillin, 4 to 8 percent of sodium carbonate, 10 to 30 percent of analginum, and the balance of anhydrous dextrose. In the composition, the gentamycin sulfate and the amoxicillin are synergized to kill pseudomonas aeruginosa, can reduce the occurrence probability of pathogeny drug resistance, and increase the sensitivity of pathogeny to the composition; the sodium carbonate has the effect of solubilizing the amoxicillin, and can improve the antibacterial effect of the gentamycin sulfate; and the analginum has the effect of defervescence and anti-inflammatory. The composition has the functions of killing the pathogency, effectively resisting pathogenic bacteria and clinical symptoms caused by the pathogenic bacteria, addressing both the symptoms and root causes, effectively treating the infection of pseudomonas aeruginosa in chicken, and reducing the pathogeny drug resistance by reasonable compatibility of the components. The composition can be dissolved in water, and is convenient to use.