712results about How to "Avoid degradation" patented technology

The invention provides an application of a turnip crinkling virus P8 in inhibiting RNA silencing, and the nucleotide sequence of the P8 gene is as shown in SEQ ID NO: 1. Researches find that P8 has a silent inhibition function and can inhibit mRNA (messenger ribonucleic acid) of GFP (green fluorescent protein) from being degraded, so that the expression quantity of GFP protein is increased; in addition, it is found that the P8 can also increase the number of particles of an arabidopsis thaliana mRNA degradation pathway Procness body (a compound formed by interaction of Dcp1 protein and Dcp2 protein), and research results lay a foundation for clarification of P8 functions.

The invention discloses a method for preparing tegorasone pyroglutamate, and the prepared tegorasone pyroglutamate product has the advantages of reduced residual solvent content, good stability, and facilitation of the improvement of the product quality and the guarantee of the medication safety. The preparation method is simple and rapid in preparation process, beneficial to saving of production cost and suitable for industrial production.

The invention discloses a production process of antistatic polyamide fiber, and relates to the technical field of textile chemical fiber production, the antistatic polyamide fiber comprises the following raw materials by weight: 30-40 parts of polyethylene glycol terephthalate, 60-70 parts of polyamide, and 3.6-4.8 parts of master batch. The master batch is prepared from the following raw materials in parts by weight: 80 to 90 parts of polyamide, 2 to 4 parts of an antistatic agent, 0.7 to 0.9 part of an anti-ultraviolet agent, 0.7 to 0.9 part of an auxiliary agent, 2.5 to 3.5 parts of a toughening agent and 0.5 to 0.7 part of a dispersing agent. The synthesized antistatic agent contains carbon fibers, a polyether structure, an amide structure and a DOPO structure, so that the antistatic property and flame retardance of the antistatic polyamide fiber are improved. The synthesized anti-ultraviolet agent contains a benzimidazole structure, a sulfydryl ester structure, a hindered phenol structure and an amide structure, so that the ultraviolet aging resistance of the antistatic polyamide fiber is improved.

This patent application discloses a self-assembled recombinant collagen, a preparation method and use thereof. The amino acid sequence of the self-assembled recombinant collagen of the present invention is shown in SEQ ID No. 1, and it can self-assemble in an aqueous solution to form a heptamer structure. The self-assembled recombinant collagen has excellent long-term storage stability, effectively avoiding the problem of protein degradation during storage.

The invention relates to the technical field of compositions, in particular to an anti-aging composition for increasing corium layer collagen and a preparation method of the anti-aging composition. Comprising the following steps: preparing sargassum fusiforme polysaccharide; preparing a composite sargassum fusiforme polysaccharide stabilizer; and compounding and preparing the traditional Chinese medicine extract. The anti-aging composition is prepared by compounding the balm extract, the pistacia chinensis extract, the mulberry extract, the collagen tripeptide and the sargassum fusiforme polysaccharide, all the components are properly compounded, the obtained anti-aging composition and oral liquid are not prone to precipitation in the storage process, loss of nutritional ingredients is avoided, and the anti-aging effect is good. According to the present invention, the components have the obvious synergistic effect, such that the collagen secretion can be promoted while the oxidative stress, the collagen degradation and the skin inflammation can be inhibited so as to substantially increase the collagen content of the skin corium layer, and the anti-aging effect on the skin can be effectively achieved.

The invention belongs to the technical field of biology, and provides an electroporation buffer solution applied to exosome electroporation, the pH value is 6.8-9.8, the osmotic pressure is 80-320 mosm, water is used as a solvent, and the electroporation buffer solution comprises the following components: 15-25% w / v of iodixanol, 1.035-1.265 mM of KH2PO4, 22.5-27.5 mM of KCl, 0.18-0.22 mM of EDTA-2Na and 18-22 mM of HEPES. The electroporation buffer solution provided by the invention can improve the loading efficiency of the load and reduce damage to an exosome membrane structure and internal bioactive molecules in an electroporation process. The electroporation buffer solution can effectively reduce aggregation and fusion phenomena of exosomes after electroporation, and improves the stability and integrity of the exosomes. The electroporation buffer solution provided by the invention can improve the application degree of the exosome as a targeting drug delivery system.

According to the method, a one-pot copolymerization method is adopted, MBAA and borax serve as cross-linking agents, zwitterionic polyelectrolyte hydrogel containing SBMA, PVA, THMA and AMPS is prepared, and the zwitterionic polyelectrolyte hydrogel has excellent adhesion performance and biocompatibility and is suitable for the field of biological medicine. According to the method, the physical characteristics of the hydrogel are enhanced due to crosslinking sites and hydrogen bonds of polyvinyl alcohol. The cationic and anionic groups of SBMA improve the adhesion performance, and the reaction monomer THMA provides hydrogen-bond interaction to further promote adhesion, so that the prepared hydrogel adhesive shows excellent adhesion performance and biocompatibility, and is suitable for biological medicine application of wound dressing, drug release systems, tissue engineering and the like.

The invention belongs to the technical field of biology, and particularly relates to a reagent combination and a kit for extracting nucleic acid through a paramagnetic particle method and application of the reagent combination and the kit. The reagent combination or the kit does not adopt beta-mercaptoethanol with pungent smell or dithiothreitol needing to be stored at low temperature as an antioxidant, but adopts tris (2-formylethyl) phosphine hydrochloride and / or metabisulfite as an antioxidant, belongs to common salt chemical reagent powder, can be stored at normal temperature, and can be used for preparing a reagent for the first time. Manual addition by experimenters before an experiment is not needed, so that nucleic acid (RNA) released by splitting decomposition can be effectively prevented from being oxidized and denatured, and the integrity of extracted nucleic acid (total RNA) fragments is ensured; especially, the metabisulfite is commonly used in food additives, does not cause harm to the body, and is non-toxic and non-volatile.

The invention relates to the technical field of preparation of organic compounds, in particular to 2-chlorophenylhydrazine hydrochloride and a preparation process thereof. The 2-chlorophenylhydrazine hydrochloride is prepared from 500-600 parts of ethyl alcohol, 500-600 parts of stannous chloride solution, 300-350 parts of hydrochloric acid solution, 100-120 parts of 2, 4-dichloronitrobenzene and 10-12 parts of reduced iron powder. According to the preparation method, 2, 4-dichloroaniline hydrochloride is firstly prepared by adopting 2, 4-dichloronitrobenzene as an initial raw material, and due to the relatively stable structure, the chemical property of an intermediate product can be better kept unchanged in the storage, transportation and subsequent reaction waiting links in the whole preparation process; due to the stability, unnecessary chemical reaction or degradation caused by external environment factors can be effectively avoided, so that the subsequent 2-chloroaniline hydrochloride extraction step can be carried out on the basis of a stable starting material, and the stability basis of final product extraction is improved.

The invention discloses a pesticide microcapsule and application thereof, and belongs to the technical field of pesticides. The pesticide microcapsule is prepared by the following method: adding pesticide active ingredients into ethyl acetate, then adding polylactic acid, and uniformly stirring to obtain an organic phase; the pesticide active ingredient is composed of a bifenthrin-clothianidin compound and piperine according to a mass ratio of 1: (1-3); dissolving polyvinyl alcohol in water to obtain a water phase; under an ice-water bath condition, dropwise adding the organic phase into the water phase, and simultaneously stirring to form an emulsion; and stirring, evaporating, centrifuging, washing and drying the emulsion to obtain the pesticide microcapsule. The bifenthrin, the clothianidin and the piperine are compounded to prepare the pesticide microcapsule, so that the pesticide resistance of pests due to the action of a single medicament is effectively avoided, the piperine not only directly has a toxic effect on the pests, but also can enhance the insecticidal effect of the bifenthrin and the clothianidin, and 1 + 1gt is realized; and 2, a synergistic effect is achieved.

The invention discloses a concentration device capable of ensuring the stability of an organic solution, and relates to the technical field of organic matter purification, the concentration device comprises a central tower, the interior of the central tower is divided into a concentration cavity and a regeneration cavity left and right, heating devices are arranged in the concentration cavity and the regeneration cavity, one side of the concentration cavity is connected with a liquid inlet pipe, and the other side of the concentration cavity is connected with a liquid outlet pipe. The bottom is connected with a liquid outlet pipe; the first cooling tower and the second cooling tower are arranged on the left side and the right side outside the central tower respectively, condensing devices are arranged in the first cooling tower and the second cooling tower, and liquid outlet pipes are connected to the bottoms of the first cooling tower and the second cooling tower; the rotating disc system comprises rotating discs which rotate on the front surface and the rear surface in the central tower respectively and penetrate through the concentration cavity and the regeneration cavity, the two rotating discs are fixedly connected through a central shaft, and a plurality of adsorption assemblies for adsorbing organic matters are distributed between the two rotating discs around the circumference of the central shaft; according to the invention, efficient concentration and stable protection of the organic solution at low temperature are realized.

The invention provides application of a P8 gene, or a P8 gene coding protein, or a recombinant vector or host bacteria containing a P8 gene coding region in improvement of GFP (Green Fluorescent Protein) expression quantity and / or inhibition of degradation of an mRNA (Messenger Ribonucleic Acid) attenuated substrate taking GFP as a reporter gene. The research finds that the P8 has a silence inhibition function, can inhibit degradation of a nonsense mediated mRNA decay substrate taking GFP as a reporter gene and degradation of an endogenous nonsense mediated mRNA decay (NMD) substrate of arabidopsis thaliana, can improve the mRNA expression quantity of AT1G0106020, RPS6, SMG7, AT5G35490, AT5G64430, AT1G36730, AT4G3900 and AT5G22570, and can reduce the expression quantity of AT1G72450 and AT2G400, and the research result lays a foundation for clarification of the function of the P8.

The invention belongs to the technical field of composite plant extracts, and discloses a composite plant extract and a preparation method and application thereof.The composite plant extract comprises wheat germ peptide and swertiamarin, and the mass ratio of the wheat germ peptide to the swertiamarin is 1: (0.8-1.2); the types and quantity of amino acids in the wheat germ peptide meet the following conditions: (1) Glu + Lys + Pro + Val + His + Gly is greater than 32%, and (2) Gly + Ala + Val + Ile + Pro + Thr + Lys + His is greater than 62%. The stability of swertiamarin in the active component of the composite plant extract provided by the invention is high. In order to repair and relieve problem skin, the wheat germ peptide and the swertiamarin can increase target expression of different pathways and can also synergistically promote target expression on the same pathway, and the wheat germ peptide and the swertiamarin can also promote mutual expression of targets among the pathways, so that the effect of repairing and relieving the problem skin is achieved. And the soothing and repairing effects on the skin are improved through multi-dimensional synergy.

The invention relates to a perovskite solar cell and a preparation method thereof, and belongs to the technical field of solar cells. The perovskite solar cell comprises a conductive substrate, a hole transport layer, a passivation layer, a perovskite layer, an electron transport layer and a metal electrode which are arranged in sequence, the material of the passivation layer is selected from one or more of mercaptoethylamine, ethylenediamine and propylamine; and the thickness of the passivation layer is 1 nm to 10 nm. Through the introduction of interface passivator molecules, the interface between the hole transport layer and the perovskite layer is improved. The surface wettability of the PTAA thin film is enhanced, so that the perovskite precursor solution can form a uniform and compact perovskite layer on the PTAA / SCAs thin film, the carrier separation and transmission efficiency at an interface is improved, and the stability of a device is enhanced.

The invention discloses a gene engineering exosome and a slow release method and application thereof, the gene engineering exosome is derived from human adipose-derived stem cells, si-tgfbr2 is loaded in the gene engineering exosome, the si-tgfbr2 is specific siRNA aiming at a Tgfbr2 gene, and the gene engineering exosome can regulate and control proliferation of VSMCs, inhibit transformation of the VSMCs from a contraction phenotype to a synthetic phenotype when the VSMCs are stimulated, and inhibit the growth of the VSMCs. According to the present invention, the gene engineering exosome can be used to maintain the normal structure and the function of the blood vessel, and the sustained release effect of the content in the gene engineering exosome can be achieved by wrapping the gene engineering exosome in the PHA biodegradable material, such that the local treatment concentration can be easily stabilized, the drug administration frequency can be easily reduced, the lasting time of the treatment effect can be easily prolonged, and the treatment gene can be effectively delivered to the target cell; the treatment effect is improved; when being used for modifying a small-caliber artificial blood vessel, the small-caliber artificial blood vessel can be improved in biocompatibility and functionality, and can be prevented from being implanted into the blood vessel for remodeling unbenign hyperplasia stenosis; the invention not only provides a new thought and method for the treatment of vascular diseases, but also has important clinical application value and popularization prospect.

The invention discloses an ultrahigh-voltage direct-current shielding material and a preparation method thereof, and the shielding material is prepared from the following raw materials in parts by mass: 65-80 parts, preferably 70-80 parts, of matrix resin; 15 to 25 parts of carbon black-MXene-ionic liquid composite conductive agent, preferably 18 to 23 parts of carbon black-MXene-ionic liquid composite conductive agent; 0.2 to 5 parts of an antioxidant, preferably 0.5 to 2.5 parts of the antioxidant; 1-2 parts, preferably 1-1.5 parts, of a lubricant; 0.5 to 2 parts of cross-linking agent, preferably 0.8 to 1.2 parts of cross-linking agent. By introducing the MXene-ionic liquid modified superconductive carbon black, the conductive effect is improved, the use amount of the carbon black is reduced, and uniform dispersion of the conductive filler is realized, so that the generation of surface bulges is reduced, the surface smoothness of the shielding material is improved, and meanwhile, due to the synergistic conductive effect of the ionic liquid and MXene, the shielding material has good conductivity. The PTC effect of the shielding material is reduced; and the generation of space charges is reduced.

The invention discloses selenium disulfide shampoo with a good suspension effect and a preparation method of the selenium disulfide shampoo. The selenium disulfide shampoo comprises the following raw materials in percentage by weight: 0.05-1% of selenium disulfide particles; 0.2-6% of a high-molecular polymer capable of suspending selenium disulfide particles; 0.5 to 5% of a polyol; and 0.05%-0.1% of a chelating agent. The selenium disulfide shampoo has the advantage of being good in suspension effect, and the problems that in the using process of existing selenium disulfide shampoo, due to the fact that the dispersion uniformity and suspension stability of selenium disulfide in the shampoo are poor, the selenium disulfide is likely to be precipitated in a shampoo container, the concentration of the selenium disulfide before and after use is different, and the selenium disulfide cannot be precipitated in the shampoo container are solved. The treatment effect of the selenium disulfide shampoo on a patient is influenced.

The invention relates to a transcription factor gene specific fragment for delaying softening of postharvest apple fruits and a regulation and control method, and belongs to the technical field of plant genetic engineering. The MdWRKY33 transcription factor gene in an apple plant with poor storability is knocked out or silenced by using a transcription factor gene specific fragment as shown in SEQ ID NO.1 in a nucleotide sequence table, so as to delay the softening of postharvest apple fruits. The specific operation comprises the following steps: cloning a transcription factor gene specific fragment into a virus silencing vector pTRV2 to obtain a recombinant plasmid; respectively transferring the auxiliary vector pTRV1 and the recombinant plasmid into agrobacterium tumefaciens GV3101 strain cells by using a freeze thawing method to respectively obtain strain cells A and strain cells B; respectively carrying out culture medium culture and infection solution suspension treatment, and then preparing a mixed infection buffer solution; and immersing the apple fruits in the mixed infection buffer solution, and carrying out vacuum treatment to obtain the instantly silent apple fruits. Ethylene biosynthesis and cell wall degradation in the apple fruits are inhibited, and softening of the picked apple fruits is delayed.

The invention relates to a skin care composition and application thereof, and belongs to the technical field of cosmetics. The invention provides a skin care composition which comprises ginsenoside RG2 and III-type collagen, the composition can effectively inhibit secretion of metal matrix protease MMP1 and remarkably increase gene expression of the III-type collagen and has a synergistic anti-wrinkle effect, and the ginsenoside RG2 and the III-type collagen used for preparing cosmetics are high in price, so that the skin care composition has a good anti-wrinkle effect. In this way, the usage amount of ginsenoside RG2 and III type collagen can be reduced, and the ginsenoside RG2 and III type collagen can exert equivalent functions under the condition of low usage amount, so that the cost is saved, and meanwhile, a better anti-wrinkle effect can be achieved.

The invention discloses a near-infrared light nano probe as well as a preparation method and application thereof. The preparation method of the near-infrared nano probe comprises the following steps: dissolving polylactic acid-co-acetic acid in an acetonitrile solution, and adding lecithin and 1, 2-dipalmitoyl-sn-glycerol-3-phosphatidyl glycol to obtain a solution A; dissolving indocyanine green in an ethanol solution to obtain a solution B; and mixing the solution A and the solution B, and carrying out ultrasonic treatment to obtain the near-infrared nano probe. The near-infrared light nanoprobe can be used for imaging diagnosis of acute kidney injury, and effectively solves the problems of long diagnosis time, poor stability, high in-vivo clearance rate, low cell absorption rate and the like. Compared with existing ICG nano-particles, the ICG nano-particles are high in biological tissue penetrability, high in resolution ratio, low in phototoxicity and good in fluorescence imaging effect in an acute kidney injury model and have wide application prospects in AKI clinical diagnosis.

The invention discloses a liver function biochemical composite quality control product as well as a preparation method and application thereof. The quality control product comprises 12 analyte raw materials and the following non-analyte raw materials: 5 to 12 g / L of sodium chloride, 0.5 to 2 g / L of casein sodium salt, 5 to 20 g / L of mannitol, 0.05 to 0.2 g / L of Tween 20, 1 to 20 mg / L of bright aprotinin, 10 to 60 g / L of trehalose and 0.05 to 0.2 g / L of PC300. And matrix liquid: 20-80% of quality control substance matrix liquid and 20-80% of buffer solution. The liver function biochemical composite quality control product disclosed by the invention has high compositing property, contains 11 important liver function biochemical indexes, is excellent in component uniformity and stability, ensures the precision of each index, and meets the requirements of daily quality control.

The invention belongs to the field of biological medicine, and relates to application of an RINL antagonist in prevention and treatment of hyperuricemia. Specifically, the invention provides an application of an RINL gene or an encoding protein thereof, and the RINL gene or the encoding protein thereof: (1) is used as a marker for diagnosis, detection or prognosis of hyperuricemia; (2) preparing a reagent or a kit for diagnosing or detecting hyperuricemia; or (3) the compound is used for preparing a medicine for preventing and / or treating hyperuricemia. The RINL provided by the invention is an important related gene in the occurrence and development process of hyperuricemia, and is also a potential hyperuricemia treatment site. RINL expression is inhibited, and the uric acid excretion capacity of cells and mice is remarkably improved.

The invention relates to the technical field of textile materials, and particularly discloses high-strength screen cloth and a preparation method thereof. The high-strength screen cloth is prepared from the following raw materials: caprolactam, p-phenylenediamine, adipic acid, diphenyldicarboxylic acid, a modified monomer, zinc diethyl hypophosphite, divinyl benzene, modified glass fibers, an antioxidant and a lubricant. The preparation method comprises the following steps: preliminarily polymerizing caprolactam, p-phenylenediamine, adipic acid, biphenyldicarboxylic acid and the modified monomer, then adding the modified glass fiber, zinc diethyl hypophosphite and divinyl benzene for continuous reaction to obtain a polyamide copolymer, and finally performing melt spinning and weaving on the polyamide copolymer, the antioxidant and the lubricant to obtain the required high-strength mesh cloth. The high-strength screen cloth prepared by the invention has excellent mechanical properties and aging resistance, is suitable for being applied to the fields with high-performance requirements, such as constructional engineering materials and special protective equipment, and is high in practicability and wide in application prospect.

The invention relates to the technical field of food processing and functional drinks, and discloses a peptide-component-rich health-preserving liqueur which comprises the following components in percentage by weight: 50-65% of Maotai-flavor liquor, 10-20% of yellow wine, 3-7% of water, 10-20% of peptide components, 1-5% of plant extract and 5-10% of other components, the invention also discloses a preparation method of the health-preserving liqueur rich in peptide components, which comprises the following steps: S1, peptide treatment: carrying out directional enzymolysis on the peptide components, controlling the enzymolysis temperature at 40-50 DEG C and the enzymolysis time at 2-4 hours; and S2, microcapsule coating: coating the treated peptide components in cyclodextrin, gelatin or Arabic gum. By adopting a compound formula of multiple peptide components and combining technologies such as microcapsule coating, directional enzymolysis, low-temperature co-fermentation and nano-emulsification, the stability and bioavailability of the peptide components are remarkably improved, meanwhile, the flavor and taste of a wine body are optimized through a two-stage fermentation process, the wine body is more mellow and smoother, and the taste of the wine body is improved. The requirements of the market on the high-quality health-preserving liqueur are met.

The invention relates to the technical field of liquid silicone rubber hand feeling treating agents, in particular to a liquid silicone rubber hand feeling treating agent and a preparation method and application thereof. The liquid silicone rubber hand feeling treating agent is prepared from the following raw materials in parts by mass: 80 to 100 parts of vinyl silicone oil, 10 to 20 parts of polydimethyl silicone oil, 10 to 20 parts of reinforcing filler, 5 to 15 parts of modified hydrogen-containing silicone oil A, 2 to 6 parts of modified hydrogen-containing silicone oil B, 0.1 to 0.5 part of platinum catalyst and 0.01 to 0.1 part of inhibitor. The liquid silicone rubber hand feeling treating agent provided by the invention has good hand feeling, wear resistance, scratch resistance and stain resistance, can prevent silica gel leather from mildewing in a humid and hot environment, and has good adhesive force with the silica gel leather.

The invention discloses a hydrogen-corrosion-resistant coating material for a hydrogen-rich electrolyte environment and a preparation method thereof, and relates to the technical field of hydrogen-corrosion-resistant coating materials, the coating material comprises the following components by weight: a metal matrix reinforcing material: 30%-50% of nickel and 5%-10% of cobalt; the ceramic particles comprise 10%-20% of aluminum oxide and 5%-15% of The coating material disclosed by the invention shows excellent corrosion resistance, wear resistance and hydrogen embrittlement resistance in a hydrogen-rich electrolyte environment. The nickel-cobalt alloy layer is kept stable at high temperature and high pressure, hydrogen permeation is blocked, and material degradation is prevented. Aluminum oxide and silicon carbide improve the hardness and wear resistance of the coating, and the coating is kept intact in temperature circulation. The rare earth elements yttrium oxide and cerium oxide enhance the oxidation resistance and hydrogen embrittlement resistance. And the dispersing agent and the cross-linking agent further improve the uniformity, compactness and adhesion of the coating, so that the coating is suitable for industrial parts in high-pressure and high-stress environments.

The invention relates to the technical field of concrete, and particularly discloses recycled concrete with high heat-conducting property and a preparation method thereof. The invention discloses recycled concrete with high heat-conducting property. The recycled concrete is prepared from the following raw materials in parts by weight: cement, mineral powder, fly ash, coarse aggregate, fine aggregate, a heat-conducting agent-halloysite nanotube composite material, modified polyacrylonitrile-based carbon fiber, water and an additive. The preparation method comprises the following steps: S1, mixing and stirring the cement, the mineral powder, the fly ash, the coarse aggregate and the fine aggregate; s2, adding a heat conduction agent-halloysite nanotube composite material, modified polyacrylonitrile-based carbon fibers and 50% of water, and mixing and stirring; and S3, adding the additive and the residual water, and mixing and stirring to prepare the recycled concrete with high heat-conducting property. The recycled concrete with high heat-conducting property prepared by the invention has relatively high breaking strength and compressive strength and good heat-conducting property.

The invention discloses a preparation method of a chitosan oligosaccharide-anthocyanin nanocomposite. The preparation method comprises the following steps: dissolving purple corn anthocyanin in distilled water; dissolving chitosan oligosaccharide in distilled water; the method comprises the following steps: adding an organic solvent into a reaction kettle, reacting at room temperature in a dark place for 4-48 hours, transferring a mixed solution into a centrifugal tube, centrifuging for 10-30 minutes to separate out nano-composite precipitates and uncombined supernatant, and then adding ultrapure water for repeated centrifugation. And finally, carrying out freeze drying treatment on the precipitate to obtain the final chitosan oligosaccharide-anthocyanin nano-composite. The nano-composite prepared by the method has high stability, good dispersibility and enhanced biological activity, and provides a new way for wide application of chitosan oligosaccharide and anthocyanin in the fields of food, cosmetics, biological medicine and the like.

The invention discloses a clindamycin phosphate vaginal gel preparation device and method, and belongs to the technical field of pharmacy. The method comprises the steps that after clindamycin phosphate vaginal gel is prepared by a preparation tank, the clindamycin phosphate vaginal gel is filled into a vacuum defoaming tank through a feeding opening in the bottom of the vacuum defoaming tank, and a packaging tank is conveyed to a rotary positioning mechanism through a conveying mechanism; and the filling mechanism is used for filling the clindamycin phosphate vaginal gel stored in the vacuum defoaming tank into the packaging tank on the rotary positioning mechanism. The invention aims to solve the problems that the existing clindamycin phosphate vaginal gel is complex in preparation process and difficult to carry out constant temperature control, the preparation and filling process needs to be transferred for multiple times, the viscosity of the gel can change along with time, temperature or storage conditions, the uniformity of the gel and the use experience of a patient are influenced, and the gel is difficult to be used. And the filled finished product gel is very easy to have a large number of bubbles, so that a more transparent and uniform gel product can be obtained, and the physical property and the use comfort of the gel are improved.

The invention provides a PEF composite board and a preparation method, and relates to the technical field of insulation boards, the composite PEF board is formed by bonding a plurality of layers of board bodies, and comprises a base layer, the base layer is prepared from the following components in parts by weight: 58 to 60 parts of HDPE (High-Density Polyethylene), 4 to 6 parts of nano montmorillonite, 1 to 2 parts of benzoyl peroxide, 2 to 5 parts of BHT (Butylated Hydroxytoluene) heat stabilizer and antioxidant, 2 to 5 parts of maleic anhydride grafted polyethylene, 0.2 to 1 part of magnesium stearate and 0.3 to 0.8 part of epoxidized soybean oil; comprising a fireproof layer which is composed of the following components in parts by weight: 45-55 parts of HDPE and 5-15 parts of a phosphate ester environment-friendly flame retardant; comprising a thermal insulation layer and is prepared from the following components in parts by weight: 45-55 parts of HDPE, 5-10 parts of lignin fibers and 5-10 parts of a bio-based foaming agent formed by mixing sodium bicarbonate and citric acid. The invention has the beneficial effects that the mechanical strength, flame retardant property and thermal insulation effect of the PEF plate are obviously improved, the weather resistance and environmental protection property are enhanced, the optimal balance of high performance and cost effectiveness is realized, and the PEF plate is suitable for various building and industrial application environments.