173results about How to "Avoid degradation" patented technology

The invention relates to a diatomic iron-iron site nano-enzyme constructed by relieving oxidative stress and cartilage degeneration and used for targeted osteoarthritis treatment. According to the invention, a nitrogen-doped porous carbon anchored diatomic iron nano enzyme catalyst (Fe2-NCs) with Fe-Fe dimer coordination is developed by using a'subject-object 'strategy. The Fe2-NCs protect cartilage cells from oxidative stress induced apoptosis by modulating ROS and active nitrogen species (RNS) and promoting O2 release. In addition, Fe2-NCs restores mitochondrial function by inhibiting NOX4 expression, improving ATP production, and normalizing COXIV levels. In an in-vivo OA model, the Fe2-NCs can reduce the expression of a pro-inflammatory medium COX-2 through an NF-kappa B signal channel, inhibit the up-regulation of MMP-13 and delay the degradation of type II collagen. The invention provides a new theoretical framework and methodological approach for the treatment of osteoarthritis, and has important clinical and scientific significance.

The invention discloses uniform mixing equipment for preparing antiviral oral liquid, and belongs to the technical field of pharmaceutical preparation production, the uniform mixing equipment comprises a mixing part, the mixing part comprises a mixing equipment main body, a stirring assembly for mixing liquid medicine is arranged in the mixing equipment main body, and a first sliding groove and a plurality of teeth are arranged in the mixing equipment main body; a buffer thin-wall layer for slowly conducting heat is arranged on the stirring assembly; the cooling part comprises a liquid conveying assembly and a cooling assembly which are arranged in the stirring assembly and is used for uniformly conveying a solvent and cooling a medicament in the mixing process, and through the collaborative design of rotation of a main stirring paddle and synchronous liquid spraying of a liquid outlet, purified water is uniformly dispersed to all positions of an inner cavity of the mixing tank body in the stirring process; the problems that local liquid medicine is too thick and is slowly dispersed due to traditional top single-point water adding are solved, the raw materials and the solvent can be rapidly and evenly mixed without long-time stirring, the mixing period is greatly shortened, and meanwhile heat accumulation generated by long-time stirring is reduced.

The invention discloses composite exocarpium citri grandis stuffing with homology of medicine and food and a preparation method of the composite exocarpium citri grandis stuffing, and relates to the technical field of food processing.The preparation method of the composite exocarpium citri grandis stuffing comprises the steps that chopped exocarpium citri grandis and pericarpium citri reticulatae are mixed with rose wine and honey, pickling treatment is conducted under the sealed condition, and a pretreated flavor material is prepared; preparing red beans and white kidney beans into composite bean paste, performing stir-frying dehydration treatment, turning off a heating source after stir-frying is completed, after the temperature of a pot body is naturally reduced, adding the pretreated flavor materials into the pot, performing uniform stirring by utilizing residual heat of the pot body, and finally performing low-temperature refrigeration and ripening to obtain a finished product. The method effectively solves the technical problem that in the prior art, debitterizing treatment of exocarpium citri grandis and retention of aroma and active ingredients are difficult to consider at the same time, bitter substances of the exocarpium citri grandis can be effectively converted, meanwhile, the characteristic aroma and functional active ingredients of the exocarpium citri grandis can be completely retained, and the prepared stuffing is harmonious in flavor, fine and smooth in taste, prominent in functionality and good in taste. The encrusting machine is suitable for encrusting processing of various baked and steamed foods.

The application belongs to the technical field of beverage processing, and discloses a method for stabilizing anthocyanin in high-acid fruit juice in the presence of Vc. A stabilizer is added to fruit juice containing Vc and anthocyanin at a final concentration of 0.1-1.0 g / L, then inert gas is introduced into the fruit juice and ultrasonic degassing is performed, and the dissolved oxygen content in the fruit juice is controlled to be lower than 1 mg / L. The stabilizer is a mixture of sinapinic acid, caffeic acid and tea polyphenol, and the mass ratio of sinapinic acid, caffeic acid and tea polyphenol is 5-25:5-25:0.03-3. In one aspect, the application uses traditional sinapinic acid and caffeic acid as raw materials to inhibit the mutual promotion degradation between Vc and anthocyanin. In another aspect, the application innovatively uses tea polyphenol as a stabilizer.

This invention discloses a method for extracting high-purity PDRN from salmon testes and its application in improving skin condition, belonging to the field of bioactive ingredient extraction technology. Frozen salmon testis tissue is cleaned of blood vessels and fatty impurities, then cryogenically pulverized at -20~-25℃. The pulverized tissue is added to a pre-treatment dispersion buffer and homogenized under high pressure to obtain a DNA fragmentation solution. The precipitate is then separated by centrifugation. The precipitate is dispersed in a dedicated enzyme digestion buffer, and enzymatic digestion with protease and RNase A is performed to inactivate the enzyme. DNase I is added to the digestion solution for enzymatic cleavage. After the reaction, a stop solution is added to terminate the reaction, and the supernatant is separated by centrifugation. Ethanol is added to the supernatant for precipitation, and centrifugation yields PDRN from salmon testes. This invention, through specific buffer systems and enzymatic digestion conditions, increases the PDRN content by 40~60 kDa, allowing for better absorption and utilization by the skin, improving facial hydration and elasticity, effectively reducing facial wrinkles, and improving facial skin condition. It can be used to prepare functional cosmetics.

This invention relates to the field of flue gas treatment technology, specifically to a sulfur dioxide gas absorbent, comprising the following raw materials by weight: 90-100 parts of an aqueous amine solution and 2-6 parts of additives. In this invention, the nitrogen-zinc ion-sulfur active center of the catalyst acts as a molecular key, efficiently and reversibly coordinating and activating sulfur dioxide molecules, significantly reducing the reaction energy barrier and fundamentally improving the intrinsic absorption rate. The enhancer, with its high specific surface area, provides a large interface for the reaction. Its surface sulfonic acid groups not only buffer the decrease in system pH, maintaining the optimal acid-base environment for the reaction, but also catalyze the conversion of absorption intermediates into more stable products, thereby shifting the reaction equilibrium to the right. Under the combined effect of these two factors, the catalyst accelerates the reaction towards equilibrium, while the enhancer continuously shifts the equilibrium point, resulting in a higher absorption capacity for the absorbent.

The invention relates to the field of food, and particularly discloses a kudzuvine root, rape pollen and bean composition and a preparation method thereof, and the kudzuvine root, rape pollen and bean composition comprises the following raw materials in parts by weight: 40-60 parts of rape pollen, 20-40 parts of kudzuvine root powder, 1-10 parts of rhizoma polygonati powder, 1-10 parts of smoked plum powder, 1-10 parts of Chinese yam powder and 1-10 parts of maltodextrin. The preparation method comprises the following steps: S1, preparing materials, namely crushing and sieving the raw materials, and weighing the prepared materials; and S2, mixing the raw materials, granulating, drying, tabletting, and packaging to obtain the kudzuvine root, rape and pollen bean composition. The pollen nutritional supplement has the characteristic that the functionality and the absorptivity of the pollen nutritional supplement can be enhanced.

This utility model provides an intelligent temperature-controlled mixing device for plastic masterbatch, relating to the field of plastic product manufacturing technology. It includes: a fixing ring, a support rod, a temperature control component, a plastic substrate granule feeding hopper, a masterbatch feeding hopper, a mixing mechanism, a discharge pipe, and a switching valve. The temperature control component includes an outer shell, an inner shell, a heating element, and a control panel. The plastic substrate granule feeding hopper includes a feeding pipe, a feeding hopper, and a filter screen. The mixing mechanism includes a servo motor, a first rotating rod, a spiral stirring blade, a collar, a flat stirring blade, and a connecting component. The connecting component includes a second rotating rod, a lower stirring blade, and a connecting rod. This utility model can significantly improve the efficiency and quality of plastic masterbatch mixing and reduce the intensity of manual operation.

The invention belongs to the technical field of biological fermentation, and provides a microbial fermentation efficient extraction process and device, and the process comprises the following steps: step 1) continuous disinfection; the method comprises the steps of (1) fermentation, (2) fermentation culture, (3) cross-tank conveying, (4) temperature control and high-pressure recovery, (5) split-flow extraction and purification and (6) refining and drying, the quality of fermentation liquor is improved through a fermentation process precise control technology and a new fermentation technological process, and the product yield is improved through an efficient extraction technology.

The invention discloses a preparation method of dimeticone aerosol, and belongs to the technical field of pharmaceutical preparations. The method comprises the following steps: (a) adding 0.6%-1% by mass of dimeticone and 0.25%-0.58% by mass of menthol into a medicinal aluminum tank or stainless steel tank with the inner wall coated with an inert material, and stirring for 5-30 minutes at 100-500 rpm under the protection of nitrogen to form uniform and transparent liquid; (b) sealing and filling dimethyl ether with the purity not lower than 99.9% at the temperature of 10-20 DEG C to serve as a propellant, and enabling the content of the dimethyl ether to reach 98.42%-99.15%; and (c) valve assembly and sealing are completed under the conditions that the temperature is 15-30 DEG C and the relative humidity is smaller than or equal to 60%, and standing balancing is conducted for 12-48 hours at the temperature of 25 DEG C. According to the dimeticone propellant disclosed by the invention, the problems of poor compatibility of dimeticone and the propellant, instability in long-term storage, easiness in layering or valve blockage and the like are effectively solved by virtue of synergistic measures of limiting the component proportion, adopting high-purity dimethyl ether, controlling the particle size of menthol, using an inert coating container, protecting by nitrogen and the like.

The utility model relates to the technical field of earthworm protein processing, in particular to a multifunctional liquid nitrogen device for earthworm protein production, which comprises a processing cabinet, a cabinet door, a blanking hopper, a hopper plug, a liquid inlet, a connecting pipe, a liquid nitrogen spray head and the like, a cabinet door is rotationally connected to one side of the treatment cabinet, a discharging hopper is fixedly connected to the top of the treatment cabinet, a hopper plug used for sealing an opening of the discharging hopper is movably connected to the discharging hopper, a hopper neck of the discharging hopper extends into the treatment cabinet and is provided with a liquid nitrogen spray head, a liquid inlet is formed in the position, close to the discharging hopper, of the treatment cabinet, and the liquid inlet is communicated with the liquid nitrogen spray head through a connecting pipe. According to the quick-freezing and grinding device, through cooperation of the liquid nitrogen spray head, the grinding frame, the grinding rod, the driving mechanism and other parts, tight connection of quick-freezing work and grinding work is achieved, then the wind direction of degradation and denaturation caused by raw material transfer is avoided, and the production efficiency and the product quality are effectively improved.

This invention relates to the field of biodiversity monitoring technology and discloses a monitoring and alarm device for rare and endangered aquatic organisms based on environmental DNA. The device includes a sampling and enrichment unit, a nucleic acid in-situ extraction and purification unit, a isothermal fluorescence detection unit, an environmental factor monitoring unit, a main control and data transmission unit, a power supply and protection unit, and a remote alarm and control platform. The main control and data transmission unit obtains the pressure change rate based on the digital pressure signal output by the microcomputer-controlled pressure sensor, extracts the high-precision peristaltic pump operating time parameter to calculate the actual filtration volume, and performs a division operation to obtain the environmental DNA calibration concentration. It then calculates the dynamic transmission power value by combining the network signal strength indicator value and transmits the complete communication data packet. The remote alarm and control platform obtains a risk index based on the environmental DNA calibration concentration, maps the spatial coordinate signal to an electronic map module to generate coordinate nodes, and displays the risk index and digital environmental parameters in association.

The application provides a kind of mitochondrial function optimization additive for cell culture, preparation method and application, belong to cell culture technical field.The additive includes core active ingredient, auxiliary component and carrier, and the core active ingredient includes D-Arg-Cha-Lys-Phe-NH2 Polypeptide, ubiquinone-10 phosphate, reduced glutathione and alpha-lipoic acid.The application forms a multi-target core active system through the synergy of the four, realizes the triple synergistic protection of stabilizing mitochondrial cardiolipin, maintaining mitochondrial morphology and membrane potential, and reducing mitochondrial ROS, which can significantly improve cell culture quality.When applied, the mitochondrial cardiolipin content can be increased by more than 50%, the mitochondrial abnormality ratio can be reduced to less than 12%, the membrane potential positive cell ratio can be increased to more than 86%, the mitochondrial ROS level can be reduced by more than 40%, and the cell proliferation rate can be increased by more than 25%, which is suitable for in vitro culture of various eukaryotic cells, and the preparation process is simple and has no cytotoxicity.

The invention belongs to the technical field of fuel additives, and particularly relates to a preparation method of micro-quantum core mother liquor for an internal combustion engine. S1, raw material pretreatment and solvent dehydration; s2, preparation of a combustion and calorific value enhancement functional mother solution A; s3, preparation of a system protection function mother solution B; s4, preparing a mother solution C with stable operation and lubricating functions; and S5, compounding, degassing and finely filtering the three functional mother liquor. An eight-element synergistic system is constructed, and the micro-quantum core mother liquor for the internal combustion engine is prepared by adopting a three-module step-by-step preparation process; after methanol fuel is added, the combustion efficiency, power output and cold start performance can be synergistically improved, meanwhile, electrochemical corrosion, sealing element swelling and part abrasion are inhibited, and it is guaranteed that the fuel is stably stored for a long time; the process avoids the compatibility problem of multi-additive mixing, and solves multiple contradictions of energy improvement, material protection and fuel stability.

The invention relates to the technical field of traditional Chinese medicine and health food processing, and discloses a preparation process and application of a black ginseng extract lozenge, and the preparation process comprises the following steps: crushing starch, powdered sugar and polyethylene glycol in parts by weight, and sieving for later use; performing ultrasonic extraction and vacuum concentration on the black ginseng to obtain a black ginseng concentrated solution; slowly adding a pre-prepared black ginseng concentrated solution into the sieved starch and powdered sugar, and stirring to prepare a soft material; granulating, drying and finishing the soft material to obtain dry granules; and adding sieved polyethylene glycol into the dry particles, uniformly mixing, tabletting, forming, and sterilizing by ultraviolet radiation to obtain the buccal tablets. According to the method, ultrasonic-assisted extraction is adopted, so that degradation of heat-sensitive rare saponin is avoided; the concentrated solution is directly granulated, so that the difficulty that the extract absorbs moisture and is sticky is overcome, and the forming rate is increased; the prepared lozenge can activate a PI3K-Akt signal channel and regulate release of 5-HT, and can be used for preparing products for relieving chronic fatigue syndrome and improving spatial cognitive impairment.

The application discloses an eye lotion containing PHMB and a preparation method thereof, and belongs to the field of eye care preparations. The eye lotion takes PHMB as a bacteriostatic component, is matched with isotonicity regulators, buffers, humectants and EDTA2Na, and simultaneously adds trehalose and allantoin to construct a synergistic stable protection system. The eye lotion is prepared through a process flow of low-temperature light-shielding, preparation of a base liquid first and then addition of PHMB, two-stage sterilization filtration and aseptic filling. The application solves the technical problems that PHMB is easy to degrade in a liquid preparation, has poor stability, and the effective component is easy to attenuate after opening and use. Meanwhile, EDTA2Na and PHMB have a synergistic effect, trehalose and allantoin further stabilize the PHMB structure from a molecular level and inhibit oxidative degradation, so that the product can realize wide-spectrum and high-efficiency bacteriostasis at a low concentration. The obtained eye lotion is mild and non-irritating, clear and stable, and can still maintain stable physicochemical and bacteriostatic properties for a long time after opening, is suitable for industrial production, and can be used for daily eye cleaning, flushing, moisturizing and bacteriostatic care.

The invention discloses a stem cell-based microvesicle as well as a preparation method and application thereof, belongs to the technical field of biological tissue engineering, and particularly relates to a preparation method of the stem cell-based microvesicle, which comprises the following steps: culturing stem cells until the cell fusion degree is 80-90%, performing hypoxia treatment, and cleaning for 2-3 times; standing and culturing the cleaned stem cells, then adding a calcium ion carrier, and carrying out ultrasonic treatment; the serum-free basic culture medium containing the calcium ion carrier is immediately absorbed and removed, the cells are cleaned through PBS, culture is conducted for 24 h, and cell supernatant is collected and merged respectively; performing first centrifugation to remove cell debris; performing second centrifugation to remove dead cells and large cell debris; carrying out third centrifugation to remove organelles; fourth centrifugation is carried out, large vesicles are removed, and a final supernatant is obtained; and filtering and centrifuging to obtain a microvesicle precipitate. The preparation method of the microvesicles aims at systematically improving the yield and biological activity of the stem cell microvesicles through low-oxygen pre-stimulation, ultrasonic-calcium ion carrier synergistic induction and differential centrifugation.

This invention provides an inorganic-organic composite solid electrolyte membrane and its preparation method, belonging to the field of solid electrolyte membrane technology. The invention uses anisole and tetrahydrofuran as a mixed solvent to dissolve methyl-terminated PEO. Tetrahydrofuran weakens the interaction between the ether oxygen atoms on the PEO chain and anisole, promoting the dispersion of PEO in the mixed solvent and facilitating the formation of a homogeneous coating slurry. Meanwhile, methyl-terminated polyethylene oxide not only improves the loss of ionic conductivity after the sulfide solid electrolyte is composited with a non-ionic binder, but its methyl termination also inhibits the degradation effect of polyethylene oxide on the sulfide solid electrolyte, better preserving the high-performance characteristics of the sulfide. Furthermore, the addition of Li3PO4 increases the lithium ion transport rate in polyethylene oxide, thereby improving the ionic conductivity of the composite solid electrolyte membrane.

The application discloses a kind of diene extraction process saponification fat removal methods, first to the crude diene raw material is pretreated to remove low-boiling component, then carry out low-temperature weak base pre-saponification break down gum and waxy, middle-temperature compound saponification removes grease and fatty acid ester impurity in depth, after constant temperature stationary stratification, utilize compound solvent and carry out multistage countercurrent extraction, again by washing, reduced pressure desolventization, vacuum drying and obtain finished product.The application is by grading temperature control, step by step, effectively avoids emulsification, impurity removal effect is good, finished product purity and material yield significantly improve, reagent and three waste emissions are reduced.The process can be used for batch production, and can be matched with automatic equipment to realize continuous operation, process adaptability is strong, suitable for industrial scale popularization and application.

The utility model belongs to the technical field of alkannin extraction, in particular relates to an alkannin extraction system, and aims to solve the problems of low extraction efficiency and unsmooth liquid drainage caused by difficulty in uniformly and circularly spraying layered materials in a temperature-pressure coordinated and controllable closed environment and easiness in blockage of a liquid outlet at the bottom of a tank in the conventional alkannin extraction device. According to the scheme, the extraction device comprises an extraction tank, a storage screen frame, an electric heating wire, a liquid spraying ring and a liquid spraying pipe, the pressure in the tank is adjustable in a stepped mode through a pressurization assembly, and the temperature in the tank is adjustable in a stepped mode through the electric heating wire; the bottom end of the liquid spraying pipe is connected with a pressing sleeve pipe, the tank bottom is connected with an alignment bottom pipe, the pressing sleeve pipe is movably inserted into the alignment bottom pipe, a pipe body of the pressing sleeve pipe is provided with filter screen holes, a pipe body of the alignment bottom pipe is provided with a liquid passing notch, and the positions of the pressing sleeve pipe and the alignment bottom pipe are adjustable. According to the utility model, efficient extraction and convenient cleaning of alkannin are realized through temperature and pressure stepped cooperative control, internal and external dual-circulation spraying and a tank bottom filtering structure capable of switching an extraction mode and a cleaning mode.

The invention belongs to the technical field of fruit and vegetable juice processing, and provides a preparation technology of concentrated clear asparagus juice. According to the process, high retention rate and efficient clarification of functional components of asparagus are realized through the steps of gradient heat treatment, composite enzymolysis, two-stage centrifugal separation, enzyme deactivation-ultrafiltration coupling, low-temperature concentration and the like. Particularly, a complex enzyme preparation in a specific ratio is combined with a 50kDa ultrafiltration membrane, so that the membrane pollution index is reduced by 60% while the clarification effect is ensured. The rutin retention rate of the concentrated clear asparagus juice produced by the process reaches 82.7%, and the turbidity is 1t; the method has remarkable technical advantages and economic benefits.

The invention relates to the technical field of hydrangea hemsleyana leaf sampling, in particular to a hydrangea hemsleyana leaf white and green tissue multifunctional visual sampling device which comprises a machine body, an objective lens module capable of moving front and back is arranged on the back of the machine body, and a sampling module used for separating and sampling leaves is installed on the objective lens module. The sampling module comprises a sampling unit and an adjusting unit, the sampling unit comprises a cutter capable of being in contact with a blade and cutting the blade open and an extractor for sampling the blade, and the extractor can spray out low-temperature gas and freeze and fix a sample. According to the method, the taken-out sample is quickly frozen, so that the problem that RNA (Ribonucleic Acid) is degraded due to the fact that the sample cannot be frozen in time after being taken out is solved.

The utility model relates to the technical field of evaporation concentration, disclose a kind of low-temperature heat pump evaporator structure, including reaction component, the reaction component includes bearing frame, the top of bearing frame is fixedly connected with reaction kettle, the outer surface of reaction kettle is threadedly connected with sealing cover, the top of sealing cover is sequentially provided with raw material liquid inlet and concentrated liquid outlet, the bottom of reaction kettle is provided with steam exhaust port.The utility model is rotated by servo motor drive drive rod in cleaning component, and then drive stirring rod to carry out forced flow disturbance to raw liquid and the structure operation of synchronous rotation scraping heating pipe outer surface with drive rod as center of circle of cleaning rod, drive the forced flow disturbance of raw liquid, ensure that heat is evenly distributed and accelerate evaporation, while periodically scraping heating pipe outer surface, prevent dirt deposition, realize the beneficial effect of improving heat transfer efficiency and reducing shutdown maintenance frequency.Stirring rod three groups evenly distributed optimize the fluid dynamics performance, avoid to produce dead angle or vortex.

The invention provides a seaweed field sediment eDNA sampling method based on in-situ immobilization, and belongs to the technical field of seaweed field sediment detection.The method includes the steps that insertion parameters are adaptively adjusted by applying a vibration strategy optimization model in the seaweed field sediment sampling process, winding and grounding states are judged by inserting a state recognition model, and therefore the sampling accuracy of seaweed field sediment eDNA is improved; sampling compression is eliminated through a sediment compression self-adaptive compensation algorithm, and an optimal injection pressure curve is calculated through a multiphase flow fixing agent diffusion optimization algorithm to drive a fixing agent to uniformly cover an effective area within preset diffusion time to complete in-situ fixation. The technical problem that the DNA degradation rate is high due to the fact that a fixing agent cannot uniformly permeate in situ in the seaweed field sediment eDNA sampling process is solved.

The application discloses a kind of polylactic acid double-stretching film materials and preparation method thereof, belong to the field of biaxially oriented film.The polylactic acid double-stretching film material includes the following mass fraction of raw materials: polylactic acid 95~99 parts, melt strength improvement aid 1~5 parts, hydrolysis inhibitor 0.3~1 parts and processing aid 0.5~1 parts;Melt strength improvement aid is ultra-high molecular weight polar polymer;Ultra-high molecular weight polar polymer contains one or a combination of two of epoxy group and side chain ester group.The melt strength improvement aid improves the melt strength and melt uniformity of polylactic acid, thereby improving the yield and film thickness uniformity of polylactic acid double-stretching film;The addition of hydrolysis inhibitor improves the heat processing stability of the material, to obtain a kind of processing performance excellent, while taking into account melt strength and uniformity, thickness fluctuation small polylactic acid double-stretching film material.

This invention provides a flame-retardant, high-transmittance, and weather-resistant composite material for LED lampshades and its preparation method. By weight, the raw materials include: 80-95 parts bisphenol A type polycarbonate, 4-10 parts phenyl-containing polysiloxane microspheres, 1-4 parts mesoporous silica phosphorus-loaded microspheres, 0.3-0.8 parts silane coupling agent, 0.3-0.8 parts flame retardant, 2-5 parts organic nano-montmorillonite, 0.2-0.6 parts polycarbodiimide, 0.3-0.8 parts antioxidant, 0.3-0.7 parts light stabilizer, and 0.3-1.0 parts lubricant. The flame-retardant, high-transmittance, and weather-resistant composite material for LED lampshades provided by this invention possesses comprehensive properties of high light transmittance, high toughness, and heat resistance.

The invention relates to the technical field of energy power, and discloses a phosphoric acid fuel cell PAFC separator graphite slurry spraying-drying-cooling-detection integrated continuous process, and the slurry is prepared from raw materials including crystalline flake graphite, fluorine modified phenolic resin, a polytetrafluoroethylene emulsion, a dispersant and a dilution solvent. The process comprises the following steps: carrying out double-sided coating by using a spraying station and matching with shielding protection; a near-infrared heater is adopted for drying; the exhaust hood and the dust collector are linked to generate micro negative pressure for cooling and dust collection; and carrying out quality detection by using an online weighing platform and a visual system. The core of the method is that a closed-loop self-adaptive compensation mechanism between detection data and spraying execution is established, and coating deviation is eliminated by adjusting slurry parameters in real time. And meanwhile, the hardened blocks are shielded through visual monitoring, online switching is triggered, and secondary pollution of the bonding surface is eliminated. The problems of poor process consistency and low efficiency in the prior art are solved, and the corrosion resistance and the production controlled degree of the partition plate are improved.

This invention discloses the application of a drug in the prevention or treatment of hydrocephalus, belonging to the field of pharmaceutical formulation technology. The drug comprises a pharmaceutically acceptable formulation of one or more of the following active ingredients: compound A, compound B, or compound C, and their pharmaceutically acceptable salts, solvates, or crystal forms; compound A is carbaspirin calcium, compound B is aspirin, and compound C is salicylic acid. This invention utilizes the above-mentioned drug in the prevention or treatment of hydrocephalus. Carbaspirin calcium and its metabolites can significantly reduce ventricular enlargement in a hydrocephalus model rat, and carbaspirin calcium and its metabolites show promise in the preparation of drugs for treating hydrocephalus, providing an effective candidate drug to alleviate the suffering of hydrocephalus patients, reduce treatment risks and costs; it broadens the scope of action of carbaspirin calcium and optimizes the stability formulation of carbaspirin calcium.

The invention relates to the technical field of traditional Chinese medicine pharmacy, in particular to a preparation method and a fingerprint spectrum method of a maxingshigan pill. The method comprises the following steps: decocting and extracting semen armeniacae amarae for at least two times, and combining the obtained extracting solutions to serve as a liquid-phase component for pelleting; performing low-temperature drying and crushing on the bitter apricot kernel dregs to obtain bitter apricot kernel dreg powder, and mixing the bitter apricot kernel dreg powder with a gallnut extract to obtain bitter apricot kernel functional powder; weighing ephedra, liquorice and gypsum according to the formula ratio, crushing, and mixing with the bitter apricot kernel functional powder to obtain composite powder for pelleting; dividing the semen armeniacae amarae extracting solution into a first liquid phase for nucleation and a second liquid phase for pill growth to form a primary pill core, and gradually growing the primary pill core to form a pill body; and after the pill body reaches a preset particle size, carrying out surface shaping on the pill body, and drying at 60 DEG C for 3 hours to obtain a finished product of the Maxingshigan pill. According to the invention, efficient, stable and high-quality preparation of the maxingshigan pill is realized.

The present disclosure relates to the technical field of extruders, and one embodiment of the present disclosure provides a cable extruder facilitating temperature control, which comprises an extruder body, a feeding box and a circulating water tank, the feeding box is arranged at the top of the extruder body, the circulating water tank is arranged at the bottom of the extruder body, a circulating cooling assembly is arranged on the circulating water tank and the extruder body, a top frame is fixed at the top of the feeding box, a feeding preheating assembly is arranged on the top frame, and the circulating cooling assembly comprises a pair of outer covers, a convex layer is attached to the two end faces of the outer cover, and a water inlet cover is arranged on the outer cover at the top. Through the above technical solution, the technical problem that the violent friction between the screw and the barrel and the material shearing will generate a large amount of heat, resulting in a sharp rise in the temperature in the barrel and uneven distribution, and the existing equipment lacks an effective preheating and temperature control mechanism for the pellets or powder entering the extruder, and the low-temperature material directly put into the high-temperature barrel will cause unstable melting speed due to the large temperature difference.