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36results about How to "Excellent long-term storage stability" patented technology

Clethodim amine salt as well as preparation method and application thereof

ActiveCN119390631AExcellent long-term storage stabilityImprove herbicidal activityBiocideOrganic chemistry methodstert-ButylamineWater dispersible
The invention discloses clethodim amine salt as well as a preparation method and application thereof, the clethodim amine salt is clethodim tert-butylamine salt, and the chemical structural formula of the clethodim amine salt is as follows: # imgabs0. The invention discloses the clethodim tert-butylamine salt, and the clethodim tert-butylamine salt is characterized by various means. The prepared clethodim tert-butylamine salt is good in stability, meanwhile, the herbicidal activity of the prepared clethodim tert-butylamine salt is not weaker than that of clethodim, and the stability and the herbicidal activity of the prepared clethodim tert-butylamine salt are both superior to those of other clethodim amine salts reported in documents. The prepared clethodim tert-butylamine salt is low in degradation rate in the high-temperature heat storage process and can be stored for a long time more easily compared with clethodim, and commercial products of the clethodim tert-butylamine salt can be kept more stable in the shelf life. The clethodim tert-butylamine salt prepared by the invention is high in melting point, is solid at normal temperature, can be processed into richer dosage forms as a herbicide, can be expanded to water dispersible granules (WG), wettable powder (WP) and other new dosage forms from the current dosage forms mainly comprising clethodim emulsifiable concentrate (EC), and is good in commercial prospect.
Owner:YIFAN AGRI CHEM PLANT ZHEJIANG PROV

Self-assembling recombinant collagen, preparation method and use thereof

ActiveCN115947828BExcellent long-term storage stabilityavoid degradationConnective tissue peptidesSurgeryEngineeringCollagenan
This patent application discloses a self-assembled recombinant collagen, a preparation method and use thereof. The amino acid sequence of the self-assembled recombinant collagen of the present invention is shown in SEQ ID No. 1, and it can self-assemble in an aqueous solution to form a heptamer structure. The self-assembled recombinant collagen has excellent long-term storage stability, effectively avoiding the problem of protein degradation during storage.
Owner:SHAANXI GIANT BIOTECHNOLOGY CO LTD

Preparation method of polythiol compound and optical resin lens

PendingCN119462449AExcellent long-term storage stabilitylow costSulfide preparationOptical elementsPolymer sciencePolyol
The invention discloses a preparation method of a polythiol compound and an optical resin lens, and belongs to the technical field of new organic materials. The preparation method of the polythiol compound comprises the following steps: mixing polyhydric alcohol as shown in a formula 1, thiourea and hydrochloric acid for reaction, and hydrolyzing to obtain the polythiol compound as shown in a formula 2, wherein the total content of sulfides and polysulfides in the thiourea is less than 0.5%. According to the preparation method, by-products are reduced by controlling the total content of sulfides and polysulfides in the raw material thiourea, so that the long-term storage stability of the chromaticity of the polythiol compound is improved. An optical resin lens prepared from the polythiol compound is stable and qualified in yellow index, low in cost, suitable for large-scale industrial production and capable of meeting increasing social requirements.
Owner:EFIRM NEW MATERIAL CO LTD

Antioxidant type suspended emulsion terminator for PVC (Polyvinyl Chloride) and preparation method of antioxidant type suspended emulsion terminator

The invention belongs to the technical field of resin polymerization additives, and particularly relates to an antioxidant type suspended emulsion terminator for PVC (polyvinyl chloride) and a preparation method thereof, the antioxidant type suspended emulsion terminator comprises the following raw material components in parts by mass: 5-30 parts of phenolic antioxidant; 5 to 20 parts of a thioester antioxidant; 0.1-5 parts of an ultraviolet light absorber; 0.1 to 5 parts of a chain terminator; 1-10 parts of a heat stabilizer; 0.1 to 7 parts of a stabilizer; 0.1 to 5 parts of an emulsifier; 0.1-5 parts of a wetting dispersant; according to the invention, through the combination of the selected main and auxiliary antioxidants and the combination of the ultraviolet light absorber and the heat stabilizer, the defect structure of PVC is improved at the end of PVC polymerization, and meanwhile, the combination of the main and auxiliary antioxidants can quickly decompose peroxide and hydroperoxide at the later stage of processing; compared with the prior art, the whiteness and thermal stability of PVC in the early stage are good, the anti-yellowing effect and the long-term aging resistance of PVC in the later processing are more emphasized, the performance of PVC in the dynamic thermal stability is improved, and the volume impedance and the initial coloring are low.
Owner:DORDA (XIAN) NEW MATERIAL CO LTD

Pickering emulsion based on self-assembled particles of silk fibroin and method for preparing same

PendingCN122499046AExcellent long-term storage stabilityImprove heat stability
This invention discloses a Pickering emulsion based on silk fibroin self-assembled particles and its preparation method. The preparation method includes the following steps: adjusting the pH of the silk fibroin solution to 4.0-4.5, adding NaCl to a final concentration of 0.05-0.1 mol / L, mixing, and then heating to 40-50 °C and allowing it to stand at a constant temperature. Using the obtained silk fibroin self-assembled particle dispersion as the aqueous phase and vegetable oil as the oil phase, the mixture is mixed with excipients and homogenized by high-speed shearing to obtain a primary emulsion. This primary emulsion is then treated by high-pressure microfluidic jet to obtain the Pickering emulsion based on silk fibroin self-assembled particles. This method requires no chemical modification or exogenous reagents, is green and simple, and does not use organic solvents. It can prepare emulsions with high biosafety and high storage stability without emulsifiers, improving process safety and scalability, and broadening its application in the food, cosmetics, and biopharmaceutical fields.
Owner:SUDA NEW MATERIAL DEV (SUZHOU) CO LTD

Novel salt of imidazo [1, 2-a] pyridine compound, crystal form and preparation method thereof

In the novel salt of the imidazo [1, 2-a] pyridine compound, the crystal form thereof and the preparation method of the novel salt of the imidazo [1, 2-a] pyridine compound, the novel salt of the imidazo [1, 2-a] pyridine compound is azetidine-1-yl {8-[(2, 6-dimethyl benzyl) amino]-2, 3-dimethyl imidazo [1, 2-a] pyridine-6-yl} ketone citrate.
Owner:JEIL PHARM CO LTD +1

Wine containing cordyceps sinensis mycelium powder

The invention relates to the technical field of wine brewing, and discloses a cordyceps sinensis mycelium powder wine, which comprises the following components: a wine base; the content of adenosine in the cordyceps sinensis hypha powder is greater than or equal to 4.4 mg / 100g, the content of polysaccharide in the cordyceps sinensis hypha powder is greater than or equal to 1500mg / 100g, and the cordyceps sinensis hypha powder is added into the wine base according to the proportion of 4.0-5.0 g / L; the molecular weight of the sodium hyaluronate is 1.52.0 MDa, and the sodium hyaluronate is added into the wine base according to the proportion of 1.01.5 g / L; the grape wine further contains natural tartaric acid, the tartaric acid comprises citric acid or malic acid, and the content of the tartaric acid is 1.0-3.0 g / L. The cordyceps sinensis hypha powder is added into traditional wine, so that the content of bioactive components such as adenosine and polysaccharide is remarkably increased, and the wine has various health-care effects of enhancing immunity, resisting fatigue and the like. The function is enhanced, so that the grape wine not only has drinking value, but also has a health promoting effect, and is suitable for wide consumer groups.
Owner:GANSU ZUNZHONGFU TRADING CO LTD

A highly identifiable fungal fluorescent staining solution

The invention discloses a highly identifiable fungal fluorescent staining liquid, characterized in that it is made of the following components by mass percentage: fluorescent whitening agent 0.3-1.5%, background dye 0.05-0.25%, penetrant 3-13%, anti-fluorescence decay agent 1.5-4.5%, surfactant 0.01-0.05%, stabilizer 14-32%, sodium camphorsulfonate 0.1-0.4%, tea polyphenols 0.3-0.6%, nicotinamide adenine dinucleotide 0.1-0.3%, betaine 0.01-0.03%, water-soluble cyclodextrin polymer 0.01-0.03%, N, N-bis (2-hydroxyethyl) 2-aminoethanesulfonic acid sodium 0.01-0.04%, and the balance is deionized water. The invention also discloses a preparation method of the highly identifiable fungal fluorescent staining liquid. The high-recognition fungal fluorescent staining liquid disclosed by the present invention has high recognition and sensitivity, good staining effect on fungi, good long-term storage stability, convenient use, sufficient applicability, and excellent accuracy and efficiency in interpreting staining results.
Owner:WYSE IND (SHENZHEN) CO LTD

A high-activity rhodiola extract freeze-dried powder, a preparation method and application thereof

ActiveCN121243091Benhance anti-inflammatoryGet activity-boosting effects
The application provides a high-activity rhodiola extract freeze-dried powder and a preparation method and application thereof.The high-activity rhodiola extract freeze-dried powder is composed of the following components in parts by weight: rhodiola extract: 10-20 parts; mannose: 78-89 parts; xanthan gum: 1-2 parts; and other pharmaceutically acceptable adjuvants: 0-10 parts. The rhodiola extract, mannose and xanthan gum are compounded in the application, wherein the xanthan gum and the mannose are not only simple supporting agents and protective agents, but also have a synergistic effect with the rhodiola extract, and the activity is improved by 1+1+1>3. Experimental data prove that the anti-inflammatory effect of the high-activity rhodiola extract freeze-dried powder is significantly improved, and the analgesic activity is well maintained.
Owner:GUANGZHOU XIMU BIOTECHNOLOGY CO LTD

Preparation method of high-stability superoxide dismutase

PendingCN121896186Areduce attackhigh purityFood ingredient as antioxidantPeptide/protein ingredientsDismutaseMonomethoxypolyethylene glycol
The invention discloses a preparation method of high-stability superoxide dismutase (SOD), and belongs to the technical field of bioengineering and enzyme engineering. The method comprises the following steps: chemically modifying purified SOD (superoxide dismutase) under the conditions of low temperature and neutral pH (potential of hydrogen) by taking monomethoxy polyethylene glycol succinimido active ester as a modifier; carrying out ultrafiltration preliminary purification on the reaction liquid, then carrying out deep purification through ion exchange chromatography, and separating to obtain a high-purity modified product; and finally, sterilizing, filtering and freeze-drying to obtain the freeze-dried powder. According to the method, by optimizing a modification and purification process, the thermal stability and protease degradation resistance of SOD are remarkably improved, and meanwhile, most enzyme activity of SOD is effectively reserved. The prepared PEG-SOD product is high in purity and good in stability, and is suitable for preparing anti-inflammatory, anti-oxidation or anti-aging medicines and functional foods.
Owner:HUNAN PHYTOFUNCTIONAL AGRICULTURE TECHNOLOGY CO LTD

Polyethylene-polypropylene blend standard test piece for tax rule identification and preparation method of polyethylene-polypropylene blend standard test piece

The invention provides a polyethylene-polypropylene blend standard test piece for tax rule identification and a preparation method thereof, and belongs to the technical field of polyethylene-polypropylene blend content detection. The linear low-density polyethylene resin and the homo-polypropylene resin are used as main components, the stability of the standard test piece is improved through the anti-aging effect of the antioxidant, the dispersing effect is improved through the dispersing agent and the lubricating agent, the uniformity of the standard test piece is improved, the crystallinity of the standard test piece is improved through the nucleating agent, and the long-term storage stability is improved; all the components have a synergistic effect, so that the polyethylene-polypropylene blend standard test piece for tax identification, which is good in uniformity and excellent in long-term storage stability, is obtained. The preparation method provided by the invention is simple in process, and the prepared standard sample can be directly used for customs laboratory identification, laboratory detection method verification, reprocessed plastic production enterprise product quality control, measurement uncertainty evaluation, personnel training assessment and the like.
Owner:INSPECTION & QUARANTINE TECH CENT OF NINGBO ENTRY EXIT INSPECTION & QUARANTINE BUREAU

An oil-based fireproof paint and a method for preparing the same

The present application relates to the technical field of paint, and relates to an oil-based fireproof paint and a preparation method thereof.The oil-based fireproof paint comprises the following components in parts by weight: modified epoxy resin 15-19, organic silicon modified acrylic resin 5-7, silane modified ammonium polyphosphate 10-12, pentaerythritol 5-8, zinc borate 3-5, hydrotalcite coated zinc stannate composite material 10-12, boron nitride 9-11, dispersing agent 0.8-1.2, leveling agent 0.2-0.4, polyamide wax anti-settling agent 0.6-0.8, and solvent 40-60.The oil-based fireproof paint provided by the present application improves the fire resistance limit and the flame retardancy of the paint, and achieves the best fireproof protection effect;the compatibility of the ammonium polyphosphate and the oil-based resin matrix is improved, and the fireproof performance, the long-term storage stability and the medium corrosion resistance of the cured coating are improved.
Owner:HEBEI TINGXING CHEMICAL PRODUCTS CO LTD

Exosome purification preparation method and pharmaceutical composition for hemorrhagic stroke

PendingCN122587999AAdapt to special medication safety requirementsAvoid the risk of exacerbations
The application discloses an exosome purification preparation method and medicinal composition for hemorrhagic stroke, relates to the field of hemorrhagic stroke exosome preparation, and first collects a serum-free culture supernatant of human umbilical cord mesenchymal stem cells, removes complete cells, cell fragments and large-particle-size vesicles in the supernatant by low-speed and medium-speed two-stage pre-centrifugation, concentrates the supernatant through an ultrafiltration tube to obtain an exosome crude extract; the crude extract is loaded into an affinity chromatography column coated with an anti-human thrombin monoclonal antibody, and specific adsorption is performed to remove coagulation-related impurities such as a blood coagulation factor, fibrinogen and prothrombin complex compound in the crude extract. The exosome medicinal composition prepared by the application has no blood coagulation activity impurity residue, can avoid the risk of inducing intracranial secondary hemorrhage after medication, is completely suitable for the special medication safety requirements of hemorrhagic stroke, has high purity, excellent biological activity reservation and no immunogenic adverse reaction risk.
Owner:NOSAI (SHANDONG) BIOMEDICAL TECHNOLOGY CO LTD

Preparation technology for preparing chocolate essence through Maillard reaction and product

The invention relates to the field of food seasoning processing, and discloses a preparation technology for preparing chocolate essence through a Maillard reaction and a product. A preparation process for preparing chocolate essence through Maillard reaction comprises the following steps: S1, adding cocoa powder and water into reaction equipment according to a weight ratio of (4-5): (5-6), and soaking; s2, adding a compound enzyme accounting for 0.05-0.12 wt% of the weight of the cocoa powder for enzymolysis, and heating for enzyme deactivation to prepare cocoa powder enzymatic hydrolysate; and S3, taking 40-50 parts by weight of cocoa powder enzymatic hydrolysate prepared in the step S2, 2-5 parts by weight of compound amino acid, 20-30 parts by weight of compound reduced syrup and 5-10 parts by weight of a grease stabilizer, carrying out heating reaction, cooling, and passing through a colloid mill to prepare the chocolate essence. In a long-term storage process, the coating is not easily influenced by temperature, and good appearance and system stability can be kept.
Owner:DONGGUAN HUAJING BIOTECHNOLOGY CO LTD

Botulinum toxin freeze-dried preparation dosage form capable of being stored for long time

PendingCN119258203AUniform particle sizeExcellent long-term storage stabilityPowder deliveryPeptide/protein ingredientsToxinBuffering agent
The present invention relates to a composition of a botulinum toxin lyophilized dosage form that can be stored for a long period of time, comprising botulinum toxin, protamine sulfate, an isotonic agent and a buffer, and the botulinum toxin lyophilized dosage form according to the present invention reduces the rate of inactivation of botulinum toxin during lyophilization, according to the present invention, the stability of the botulinum toxin can be maintained for a longer time than the conventional botulinum toxin lyophilized dosage form, uniform particle size is formed, the same effect is exhibited at the administration site, and the side effect that the excessive toxin administration effect is exhibited only at some sites can be prevented.
Owner:DAEWOONG CO LTD

Plastic film agent capable of preventing hot water permeation, preparation method and application of plastic film agent in paper mold manufacturing

The invention provides a plastic film agent capable of preventing hot water permeation, a preparation method and application of the plastic film agent in paper mold manufacturing, and belongs to the field of plastic film agents. The preparation method of the hot water permeation prevention plastic film agent comprises the following steps: preparing a reaction base material, preparing a dropwise adding solution, and carrying out a contact reaction. The plastic film agent capable of preventing the hot water permeation can effectively avoid the influence of the plastic film agent on the mechanical property of the paper pulp mold and further improve the strength and stiffness of the paper pulp mold while avoiding the scrap falling of the paper pulp mold and effectively improving the waterproof property of the paper pulp mold; meanwhile, the bonding performance of the plastic film agent and a paper pulp molding material is improved, and the overall stability of a paper pulp molding product is improved; the long-term storage stability of the plastic film agent is further improved.
Owner:山东奥赛新材料有限公司

A continuous preparation method of high-purity hydrogen peroxide

The present invention provides a continuous preparation method of high-purity hydrogen peroxide, belonging to the field of high-purity hydrogen peroxide. The continuous preparation method of high-purity hydrogen peroxide consists of the following steps: primary continuous adsorption, secondary continuous adsorption, and resin continuous adsorption. The continuous preparation method of high-purity hydrogen peroxide of the present invention can improve the treatment effect of impurities in industrial-grade hydrogen peroxide under the premise of realizing continuous production of high-purity hydrogen peroxide, avoid the influence of impurities in industrial-grade hydrogen peroxide on treatment stability, and effectively improve the matching performance between each treatment section, so as to perform efficient and stable continuous purification and refining of industrial-grade hydrogen peroxide.
Owner:SHANDONG XINLONG TECH

A heat-triggered aqueous carbodiimide crosslinker composition and use thereof

PendingCN122255778AActivate cross-linking activityEfficient and global cross-linking activityCoatingsPolymer scienceCarboxyl radical
The application discloses a heat-triggered water-based carbodiimide crosslinking agent composition and application thereof. By introducing a latent acid and setting an alkaline environment during storage, the hydrolysis of carbodiimide and the pre-reaction of carbodiimide and carboxyl are simultaneously inhibited from the kinetic aspect, and the system is 'frozen' in a stable state. When used, the latent acid is triggered to decompose by heating, and the system pH is suddenly reduced to acidity by instantaneous release of protons, which not only quickly protonates and activates the carbodiimide, but also creates an optimal kinetic window in which the reaction rate of carbodiimide and carboxyl is much faster than the hydrolysis reaction, thereby accurately, synchronously and efficiently guiding the reaction path to the target crosslinking direction, and realizing the unification of'stable storage' and 'on-demand efficient reaction' in a single component.
Owner:HANGZHOU HAIWEITE FUTURE TECHNOLOGY CO LTD +1

Buddleja officinalis extract as well as preparation method and application thereof

The invention relates to a butterflybush flower extract as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing a buddleja officinalis raw material with an aqueous solution of polyol, performing pulsed electric field extraction, filtering, and collecting filtrate to obtain the buddleja officinalis extract. According to the method, an aqueous solution of polyhydric alcohols is used as an extraction solvent, and the functional components in the butterflybush flowers are extracted by utilizing a pulsed electric field. The buddleja officinalis extract prepared by the preparation method disclosed by the invention has excellent anti-ultraviolet, anti-oxidation and anti-inflammatory effects, and also has excellent long-term storage stability.
Owner:BEST PHARM (GUANGZHOU) CO LTD

Compound sodium nitrophenolate and thidiazuron microemulsion and preparation method thereof

PendingCN121774061ASolve the problem of large decompositionsolve decompositionBiocidePlant growth regulatorsUse medicationMicroemulsion
The invention provides a compound sodium nitrophenolate-thidiazuron microemulsion and a preparation method thereof. The microemulsion comprises an effective component, a high-molecular long-chain EO-PO polymer and an auxiliary material part, wherein the high-molecular long-chain EO-PO polymer comprises a polymer with the molar molecular weight of 5000-30000. According to the invention, a high-molecular polymer is creatively used for coating a thidiazuron active compound in a nanoscale micro-droplet state, so that the problem that thidiazuron is greatly decomposed after the thidiazuron active compound and compound sodium nitrophenolate are compounded to prepare the microemulsion is solved; meanwhile, the high-molecular polymer disclosed by the invention replaces a traditional solvent dissolution form with a form of wrapping a thidiazuron active compound, so that a slow-release effect is achieved, the long-acting property of the whole preparation is improved, the medication frequency and the dosage are less, meanwhile, the high-molecular polymer is safe to crops, the plant vigor is improved, the fruit setting rate can be remarkably increased, and the stress resistance of plants is enhanced.
Owner:PILARQUIM SHANGHAI

A non-fenretinide pellet and a preparation method thereof, and a capsule

This invention relates to the field of biomedical technology, and more particularly to a fenelazol microsphere, its preparation method, and capsules. This invention optimizes the formulation of the original fenelazol tablets, using blank pellet cores as a carrier, sodium carbonate as an alkalizing agent, and sulfobutyl-β-cyclodextrin as an excipient to prepare fenelazol microsphere capsules. Experiments show that these microspheres have excellent solubility in gastric acid, are pH-independent, and exhibit high long-term storage stability. This invention simplifies the production process, has good process stability, low production costs, and is suitable for large-scale production.
Owner:HYBIO PHARMA

Alkylamidoalkyl (meth)acrylates, their preparation and use

ActiveCN120887818BImprove herbicidal activityNot weak in herbicidal activityBiocideOrganic compound preparationMeth-tert-Butylamine
The application discloses enoxamacetone diamine salts, a preparation method and application thereof. The stability of enoxamacetone diamine salts (enoxamacetone 1,4-butane diamine salt, enoxamacetone 1,5-pentane diamine salt and enoxamacetone 1,6-hexane diamine salt) is better than that of enoxamacetone and enoxamacetone monoamine salt (for example, enoxamacetone tert-butylamine salt); meanwhile, the weeding activity of the enoxamacetone diamine salt (enoxamacetone ethylenediamine salt, enoxamacetone 1,4-butane diamine salt and enoxamacetone 1,5-pentane diamine salt) is better than that of enoxamacetone tert-butylamine salt, wherein the weeding activity of enoxamacetone 1,5-pentane diamine salt is better than that of enoxamacetone. Most of the enoxamacetone diamine salts have low degradation rate during high-temperature heat storage, are easier to be stored for a long time, have higher melting point than enoxamacetone monoamine salt (for example, enoxamacetone tert-butylamine salt), are more convenient for granulation and crushing, are more convenient for being processed into solid dosage forms such as water dispersible granules as weeding agents, have better physical properties of preparations, and have good commercialization prospect.
Owner:YIFAN BIOTECHNOLOGY (SHANGHAI) CO LTD

Long-acting anti-aging high-bond-strength elastic hybrid adhesive, preparation method and application thereof

The application belongs to the technical field of adhesive manufacturing, and discloses a long-acting anti-aging high-adhesion-strength elastic hybrid adhesive, a preparation method and application thereof. The preparation method comprises the following steps: preparing a long-acting A component with weak acidity and high storage stability, and preparing a long-acting B component with high storage stability; through synchronous improvement of the adhesive formula and process, a ternary hybrid system is adopted, and the problems of compatibility of the ternary system and hydrolysis of the MS catalyst are overcome, so that the prepared A and B components can be stored stably for a long time, the adhesive can have high strength, high elasticity, high storage stability and low cost at the same time, the adhesive is convenient to produce and can be stored stably for a long time, and the adhesive can be widely applied to the manufacturing of power battery cells and other products and can meet various actual application requirements of the industry.
Owner:GUANGZHOU BLUOSHEN NEW MATERIAL TECH CO LTD

Polyurethane emulsion as well as preparation method and application thereof

The invention belongs to the technical field of high polymer materials, and particularly relates to a polyurethane emulsion as well as a preparation method and application thereof. The polyurethane emulsion is prepared from the following raw materials in parts by weight: 35 to 50 parts of polyisocyanate, 50 to 70 parts of polyol, 3 to 5 parts of a chain extender, 1 to 2 parts of a neutralizing agent, 200 to 300 parts of water, 10 to 20 parts of an organic solvent, 0.01 to 0.05 part of a catalyst and 3 to 5 parts of functionalized aluminum oxide nanoparticles. According to the invention, the modified aluminum oxide nanoparticles are used as a functional additive of the waterborne polyurethane emulsion, so that the storage stability of the waterborne polyurethane emulsion can be remarkably improved, and the drying process of the waterborne polyurethane emulsion can be accelerated through the temperature response characteristic of the modified aluminum oxide nanoparticles, so that the polyurethane emulsion shows more excellent performance in application; the problem that the drying rate of the waterborne polyurethane emulsion is reduced due to the fact that the storage stability of the waterborne polyurethane emulsion is improved by enhancing the hydrophilicity of polyurethane in the prior art is successfully solved.
Owner:SHANDONG MICHI NEW MATERIAL TECH CO LTD

Solid dispersions, pharmaceutical compositions and their preparation methods and applications

This invention discloses a solid dispersion, a pharmaceutical composition, a method for preparing the same, and its application. The solid dispersion of this invention comprises: (1) a compound of formula () or a pharmaceutically acceptable salt thereof; and (2) a polymer carrier, wherein the polymer carrier comprises one or more of copovidone, povidone, and hydroxypropyl methylcellulose; formula ().
Owner:JIANGXI KERUI PHARM CO LTD

Compound composition for strengthening primordial qi and promoting growth and preparation process thereof

The invention provides a compound composition for cultivating primordial qi and promoting growth and a preparation process thereof, and the preparation process comprises the following steps: adding water into traditional Chinese medicine components, carrying out high-temperature extraction to obtain a basic water extract, and filtering and concentrating the basic water extract to obtain a concentrated water extract; adding a compound enzyme into the concentrated water extract for enzymolysis to obtain an enzymatic hydrolysate, adding diatomite into the enzymatic hydrolysate for targeted adsorption and filtration to obtain a primary filtrate, cooling the primary filtrate to room temperature, adding acid to adjust the pH value to 5.8-6.2, and adding a xanthan gum water solution to obtain a traditional Chinese medicine water extract; adding a bacterial suspension into the traditional Chinese medicine water extract to obtain a traditional Chinese medicine compound liquid, wherein the bacterial suspension contains inactivated lactobacillus helveticus CCFM1263; mixing bone collagen peptide and casein phosphopeptide to obtain a mixture, and dissolving the mixture in purified water in which sodium citrate is dissolved in advance to obtain a peptide premixed solution; slowly adding the peptide premixed liquid into the traditional Chinese medicine composite liquid, fully mixing, filtering and sterilizing to obtain the compound composition for cultivating the primordial qi and promoting growth.
Owner:ZHEJIANG SOCHI HEALTH TECH CO LTD

A method for preparing a bacteria-immobilized carrier, a product thereof, and use thereof in preparing a coating

The present application relates to the technical field of intelligent marine anticorrosion materials, and particularly relates to a preparation method of a solid-loaded bacterial body, a product and application of the solid-loaded bacterial body in preparation of a coating. The preparation method of the solid-loaded bacterial body comprises the following steps: dissolving a protein and a reducing sugar in water to perform a Maillard reaction to obtain an MRPs solution; mixing the MRPs solution and a Bacillus subtilis bacterial solution uniformly, and performing vacuum freeze-drying to obtain the solid-loaded bacterial body. The present application further provides a mineralized self-repairing anticorrosion coating, which comprises an epoxy resin system and the solid-loaded bacterial body dispersed in the epoxy resin system. When applied to marine anticorrosion, the solid-loaded system constructs a dense and hydrophobic calcite type calcium carbonate mineralization barrier in situ on a metal surface through microbial induced mineralization, and reduces the corrosion rate of Q235 carbon steel by more than 80%.
Owner:UNIV OF SCI & TECH BEIJING

Minoxidil nanocrystal suspension and preparation method thereof

The invention belongs to the technical field of pharmaceutical preparations, and particularly discloses a minoxidil nanocrystal suspension and a preparation method thereof, the preparation method comprises the following steps: S1, adding a stabilizer into water, and uniformly stirring to obtain a stabilizer mixed solution; s2, minoxidil is added into the stabilizer mixed solution, the mixture is put into a high-speed shearing machine to be pre-sheared until the stabilizer and minoxidil are fully premixed, and a coarse suspension is prepared; and S3, grinding the crude suspension, so as to obtain the minoxidil nanocrystal suspension. According to the minoxidil nanocrystal suspension and the preparation method thereof, a nonionic polymer and an ionic surfactant are compounded to form a stabilizer, and the preparation of the minoxidil nanocrystal suspension which is small in size, uniform in dispersion, stable in suspension, good in solubility, safe and energy-saving can be completed only through ball milling and a small amount of compounded stabilizer by utilizing a high-speed pre-shearing method before ball milling.
Owner:MOGE NEW MATERIALS (SHANTOU) CO LTD

Loxoprofen sodium oral solution and preparation method thereof

The invention provides a loxoprofen sodium oral solution, and belongs to the technical field of pharmaceutical preparations. According to the loxoprofen sodium oral solution, chlorogenic acid is used as an additive, degradation of loxoprofen sodium is effectively inhibited by adjusting the pH value of the loxoprofen sodium oral solution in a synergistic manner, and the antibacterial activity and oxidation resistance of chlorogenic acid are utilized to improve the antibacterial activity of the loxoprofen sodium oral solution, so that the long-term storage stability of the loxoprofen sodium oral solution is improved; the viscosity of the loxoprofen sodium oral solution is adjusted by using the inulin, the dispersion stability of each component is improved while the taste of the loxoprofen sodium oral solution is improved, and the loxoprofen sodium oral solution has water-retaining property, so that the storage stability of the loxoprofen sodium oral solution is further improved.
Owner:JIANGXI ZHONGZEYUAN PHARMACEUTICAL TECHNOLOGY CO LTD

Triphenylamine gallium porphyrin complex and application thereof as hole transport material

PendingCN121974917AMatch energy levelExcellent intrinsic hole transport propertiesOrganic chemistryPhotovoltaic energy generationDopantPerovskite solar cell
The invention discloses a triphenylamine gallium porphyrin complex and application of the triphenylamine gallium porphyrin complex as a hole transport layer material. The structure of the complex is shown in the following formula, wherein R represents methoxy, methylthio or hydrogen. The complex has an energy level better matched with a perovskite layer and better intrinsic hole transport characteristics, and under the condition that no chemical doping is needed, a formal (n-i-p) perovskite solar cell prepared from the complex obtains 16.25% of photoelectric conversion efficiency and is comparable with an early-stage doped Spiro-OMeTAD system. The lithium salt and the organic dopant which are easy to absorb moisture and migrate are completely abandoned, so that the problem of device degradation caused by the lithium salt and the organic dopant is radically eliminated, and the long-term stability of the device under hot, wet and running conditions is synchronously and greatly improved; the preparation process is greatly simplified, the process window is obviously widened, the production repeatability and the yield are improved, and by omitting expensive dopants and simplifying production steps and quality control links, the material and process cost is directly reduced, and the industrial application potential is improved.
Owner:SHAANXI NORMAL UNIV