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169 results about "Minoxidil" patented technology
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Minoxidil is used with other medications to treat high blood pressure (hypertension).
Minoxidil pharmaceutical foam formulation
A pharmaceutical foam formulation in a dosage form which comprises an active ingredient selected from the group consisting of minoxidil, minoxidil sulphate, other soluble minoxidil salts, and mixtures thereof. An embodiment also includes a surfactant, water, and optional further excipients. In an embodiment, the formulation is adapted to form a foam when administered by spraying.
Owner:JACQUES ELIZABETH JOAN +1
Methods, Compositions and Apparatus for Treating a Scalp
InactiveUS20100106077A1Efficient use ofSimple processElectrotherapyMedical applicatorsDocking stationLight therapy
A phototherapy light cap is a flexible, generally hemispherical cap having a light source to supply suitable dosage requirements of current and future light therapies. The phototherapy light cap may also include a rechargeable battery source, a light source or an array of light sources, a light diffuser and an interface to a recharging source that may be a docking station. A phototherapy light cap may alternatively be an insert for any commercial head dressing, preferably adapted for convenient recharging. Combining the use of a phototherapy light cap with gelatinized therapeutic agents provides a suitable treatment technique for a scalp utilizing phototherapy, heat and any suitable combination of active ingredients such as minoxidil.
Owner:TRANSDERMAL CAP
Continuous spray scalp therapy and dispensing systems for same
InactiveUS20080206156A1Relieve pressureQuick and easy and effective applicationCosmetic preparationsBiocideHair growthScalp
The present invention relates to continuous spray medications involving the scalp, such as minoxidil, finesteride, copper peptides, DHT inhibitors and androgen receptor blockers, for example, in an amount sufficient to stimulate or maintain hair growth. The scalp medication is disposed within a pharmacologically acceptable carrier solution. In further embodiments, the spray scalp medication is dispensed within a product bag containing the medication in liquid form. The product bag is disposed within a container and includes a sheet of gas impervious material having a barrier layer therein. A gaseous propellant is also disposed within the container and is substantially separated from the medication. The valve assembly is selectively operated to produce a fine mist of said medication which is non-chilling, continuous and even.
Owner:CRONK PETER J
Compositions and methods for dermally treating neuropathy with minoxidil
The present invention is drawn to adhesive solidifying formulations containing minoxidil that can be used for treating neuropathies including diabetic neuropathy. The formulation can include an amount of minoxidil, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent capable of facilitating the delivery of the minoxidil at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
Owner:ZARS PHARMA INC
Compositions of minoxidil
Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising minoxidil, and methods for using the novel compositions for treating and preventing hair loss in a region of a patient.
Owner:MCNEIL AB
Ventilated Device for Delivery of Agents to and through the Human Scalp
InactiveUS20090032049A1Promote absorptionPatient compliance is goodCosmetic preparationsBiocideScalpMoisture barrier
A method and device for administering minoxidil and other topical solutions to the scalp. The method entails administering a minoxidil preparation through a manifold that fits over the scalp of a patient, and placing a moisture barrier over the scalp for a period of time effective to enhance absorption of the minoxidil preparation by the scalp.
Owner:RABIN MICHAEL I +1
Ventilated device for delivery of agents to and through the human scalp
InactiveUS8146607B2Promote absorptionPatient compliance is goodOrganic active ingredientsCosmetic preparationsScalpMoisture barrier
A method and device for administering minoxidil and other topical solutions to the scalp. The method entails administering a minoxidil preparation through a manifold that fits over the scalp of a patient, and placing a moisture barrier over the scalp for a period of time effective to enhance absorption of the minoxidil preparation by the scalp.
Owner:RABIN MICHAEL I +1
Patches and Methods for the Transdermal Delivery of Agents to Treat Hair Loss
InactiveUS20120184894A1Preventing and/or treating an iron deficiencyPreventing hair lossHeavy metal active ingredientsCosmetic preparationsHair streamsHair growth
Embodiments of the invention provide patches for the transdermal delivery of compositions to treat an individual suffering from hair loss. Many embodiments provide an iontophoretic patch for the transdermal delivery hair growth stimulating agents for the treatment of hair loss by stimulating the growth of new hair in areas of the scalp exhibiting hair loss. The patch comprises an electrode and a reservoir containing a composition comprising iron containing compound, such as a chelated iron compound for the delivery of the therapeutically effective amount of iron. The patch can be shaped to be placed and remain on the head. Various embodiments provide methods of using embodiments of the iontophoretic patch for delivering a hair growth stimulating agent such as a chelated iron compound, minoxidil and finasteride to the scalp and other areas exhibiting hair loss. Such methods can be used for re-growing hair, and / or preventing or slowing hair loss.
Owner:INCUBE LABS
Topical administration carrier composition and therapeutic formulations comprising same
Owner:CELMATRIX CORP
Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof
InactiveUS20050163811A1Promotes hair growthPreventing hair lossCosmetic preparationsBiocideHigh concentrationEffective solution
This invention relates to a method for achieving a novel solution comprising a high percentage of a piperidinopyrimidine derivative, more particularly minoxidil. The method of the current invention results in a highly effective solution for facilitating hair growth comprising a high concentration of Minoxidil, that is not cosmetically unattractive when applied to a treatment area and that does not cause skin irritation in the treatment area. In another aspect of the invention, said solution comprising high percentage Minoxidil may further comprise co-active ingredients, such as azelaic acid. The present invention also provides a method for stimulating the growth of hair or for preventing hair loss in humans and lower animals.
Owner:REGROWTH
Finasteride and minoxidil polymeric nonoparticle, its process of preparation, aqueous suspension containing the same, pharmaceutical composition, and its use
The present invention relates to a pharmaceutical composition for topical application for the treatment of alopecia, said composition comprising polymeric nanoparticles, preferably nanocapsules containing two active ingredients, finasteride and minoxidil, additives and a pharmaceutically acceptable carrier. The invention further includes a process for the preparation of polymeric nanoparticles, preferably nanocapsules of finasteride and minoxidil, a composition suitable for topical application for the treatment of alopecia, as well as the use of said nanocapsules for the preparation of a pharmaceutical composition.
Owner:BIOLAB SANUS FARMACEUTICA LTD +1
Natural composite anti-hair-loss hair-growing liquid for external use
InactiveCN103479989AAvoid harmBlood pressure does not changeDermatological disorderCardiovascular disorderAlopecia seborrhoeicaSide effect
The invention provides natural composite anti-hair-loss hair-growing liquid for external use, belongs to the technical field of traditional Chinese medicine preparations, and solves the problem that minoxidil is added in a conventional product. The hair-growing liquid comprises raw materials of cacumen biotae, fresh ginger, polygonum multiflorum, safflower carthamus, angelica, broadleaf holly leaves, asparagus lettuce seeds, pseudo-ginseng and ginseng as well as auxiliary materials of sodium acrylate, azone and vitamins C. A clinical test proves that the hair-growing liquid has unique treatment effects for patients with alopecia seborrhoeica, alopecia areata, neuropathic alopecia, endocrine dyscrasia alopecia, nutrition metabolism alopecia and chemical alopecia; the hair-growing liquid is a pure natural extracted essence component, does not have the shortcomings of causing side effects, causing an injury to a human body, containing any chemical component, influencing hypertension and hypotension and changing blood pressure of blood vessels and blood flow, and has hair-growing and hair-blackening effects.
Owner:蔡铭成
Protein nanoparticles
InactiveUS20090191277A1Improve securityHigh transparencyPowder deliveryOrganic active ingredientsNanoparticleHair follicle
It is an object of the present invention to provide a highly safe composition comprising minoxidil and having high transparency due to the small particle size and high permeability into scalp and hair follicles. The present invention provides a protein nanoparticle which comprises minoxidil.
Owner:FUJIFILM CORP
Topical administration carrier composition and therapeutic formulations comprising same
ActiveUS20070141004A1Reduce evaporative lossReduce the evaporative lossBiocideCosmetic preparationsWhole bodyBULK ACTIVE INGREDIENT
A topical administration carrier composition including water, glycerin and polysorbate, suitable for use with compositions containing active ingredients such as minoxidil that are susceptible to volatilization and transdermal penetration in application to the body. The carrier formulation retards the evaporative and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the components of the inventive composition.
Owner:CELMATRIX CORP
Minoxidil aqueous composition containing bile acid
ActiveUS8258146B2Good effectSuppression of stickinessOrganic active ingredientsBiocideHigh concentrationOrganic solvent
An object of the present invention is to provide a liquid composition wherein minoxidil can be dissolved at a relatively high concentration (the saturating amount or above), stimulation of skin and stickiness is suppressed without containing an organic solvent, and excellent effects of percutaneous absorption is achieved. The present invention provides a liquid composition comprising (i) minoxidil, (ii) bile acid or a salt thereof, and (iii) an aqueous medium in an amount of 30% by weight or more of the weight of the composition.
Owner:FUJIFILM CORP
Composition and Methods for Treating Hair Loss
InactiveUS20120258972A1Accelerated and robust effectPromotes hair growthCosmetic preparationsBiocideCream basePhysiology
A method for treating hair loss caused by androgenic alopecia and / or male pattern baldness. The method, which not only slows hair loss but causes hair re-growth, includes approximately daily application to a subject's scalp of a novel composition comprising finasteride (Propecia® or Proscar®), dutasteride (Avodart®), and minoxidil (Rogaine®) as active ingredients in a hypoallergenic cream-based vehicle, preferably coupled with daily ingestion of 1 mg per day of finasteride (Propecia® or Proscar®), application to the scalp of 5% minoxidil (Rogaine®) foam approximately once per day, and use of a ketoconazole-containing shampoo (e.g., Nizoral®) approximately 2-3 times per week. The method described herein also resolves scalp dermatitis in atopic subjects suffering therefrom. A method for making the novel composition is also provided.
Owner:RAFI ASIF +1
Topical Treatment of Peripheral diabetic complications
InactiveUS20090018151A1Decreased microcirculationEffective treatmentOrganic active ingredientsBiocideSodium Channel InhibitorsNitric oxide
This invention relates to agents for treating, ameliorating, or preventing diabetic complications specifically diabetic neuropathy and skin ulceration by topical application of materials containing one or more arterial or venous dilation components and one or more fast sodium channel inhibitors. Particularly, the invention relates to treating or ameliorating agents that contain minoxidil and its related congeners, which have both potassium channel agonist properties and nitric oxide agonist properties as an active ingredient and which are effective against diabetic complications such as neuropathy, peripheral circulation disorders and skin ulcerations. Unique methods of delivery including delivery through impregnated socks or gloves to match the distribution of pain are also noted.
Owner:FINK EZEKIEL
High concentration glycerol-type minoxidil tincture and preparation method thereof
InactiveCN102349913AIncrease concentrationSolve Oxidation ProblemsOrganic active ingredientsOrganic non-active ingredientsHigh concentrationArginine
The invention relates to a high concentration glycerol-type minoxidil tincture for treating alopecia and a preparation method thereof. The high concentration glycerol-type minoxidil tincture of the invention comprises components of minoxidil, alcohol, glycerol, water-soluble azone, acids, ethylene diamine tetraacetic acid, arginine, cystine and water. Traditional propylene glycol is substituted by glycerol and water-soluble azone, so as to realize a minoxidil concentration of 5-15%, solve allergic problem caused by propylene glycol and realize a high minoxidil dissolving concentration; amino acids are added in the components to increase hair growing speed; when necessary, the arginine and / or sodium hydroxide is added with a pH buffer solution to stabilize a scalp pH at an optimum pH andavoid discomfort and hair shedding caused by pH change along with application of the hair grower. The invention employs a minoxidil step-by-step dissolving method with a short dissolving time to solve a problem of minoxidil oxidation during dissolving in a traditional technology.
Owner:刘国辉
Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
InactiveUS7018979B1Improve breathabilityHigh selectivityOrganic active ingredientsBiocideCyclasePotassium
Disclosed are methods of selectively delivering a medicant to an abnormal brain region and / or to a malignant tumor in a mammalian subject, including a human. A medicant is administered simultaneously or substantially simultaneously with a potassium channel agonist (other than bradykinin or a bradykinin analog), such as NS-1619,1-EBIO, a guanylyl cyclase activator, a guanylyl cyclase activating protein, minoxidil, pinacidil, cromakalim, or levcromakalim, whereby the medicant is delivered selectively to the cells of the abnormal brain region and / or to the tumor, compared to normal tissues. Thus, among the disclosures is a method of treating a malignant tumor in a human subject. Also disclosed are pharmaceutical compositions that combine a potassium channel agonist together with a medicant and a kit for enhancing the delivery of a medicant to an abnormal brain region and / or to a malignant tumor.
Owner:CEDARS SINAI MEDICAL CENT
Device For Delivery Of Agents To And Through The Human Scalp
InactiveUS20090036845A1Efficiently and uniformlyPharmaceutical delivery mechanismCurling devicesScalpMinoxidil
Owner:SMITH DAVID A
Cream for treating alopecia and its prepn
InactiveCN101019868ASignificant effectSafe to carryOrganic active ingredientsAerosol deliveryAntioxidantIrritation
The present invention discloses one kind of cream for treating alopecia. The cream is prepared with minoxidil, stearic acid, glycerol monostearate, white vaseline, propylene glycol, sodium thiosulfate, disodium edta, etc. The present invention adopts propylene glycol as both solvent and transdermal promoter, and sodium thiosulfate and disodium edta as antioxidants to prevent the oxidation of minoxidil, so as to result in even high treating effect. The cream of the present invention has obvious treating effect, no irritation, no hypersensitivity, low cost and other advantages, and is used in treating different kinds of alopecia.
Owner:AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
Device For Delivery Of Agents To And Through The Human Scalp
InactiveUS20070256212A1Promote absorptionPatient compliance is goodCosmetic preparationsHair cosmeticsScalpMoisture barrier
A method and device for administering minoxidil and other topical solutions to the scalp. The method entails administering a minoxidil preparation through a manifold that fits over the scalp of a patient, and placing a moisture barrier over the scalp for a period of time effective to enhance absorption of the minoxidil preparation by the scalp.
Owner:TRANSDERMAL CAP
Shampoo composition redounding to hair generation
InactiveCN101313881AAvoid overly irritating situationsPromote growthCosmetic preparationsHair cosmeticsMedicineHair growth
The invention discloses a shampoo composition which is favorable for hair growth, which is mixed by 2 to 10 weight percent of minoxidil, 15 to 50 weight percent of surface active agent and 40 to 75 weight percent of de-ionized water. The shampoo composite, as a daily product of the patient with alopecia, can achieve the aim of treating the alopecia in daily cleaning of hair.
Owner:李燕强
Restoration of hair
InactiveUS20130324567A1Low water solubilityEffective applicationOrganic active ingredientsBiocideWhole bodyWater insoluble
A nonirritant composition which is useful in restoring hair and which comprises a normally solid, water-insoluble hair restorer, for example, minoxidil, a normally solid Hsieh dermal penetration-facilitator for the hair restorer, for example, pentadecalactone, and a solvent or co-solvent in which the hair restorer and the facilitator are solubilized and which does not impart to the composition irritant properties, and wherein, upon application to the surface of the skin of a recipient, the hair restorer penetrates the dermal layer of the skin and with minimal systemic delivery of the hair restorer into the blood stream of the recipient.
Owner:CONREX PHARMA CORP
Minoxidil solution and preparing method of minoxidil liniment tablet
ActiveCN1857268ALess irritatingEasy to disperseOrganic active ingredientsDermatological disorderSodium thiosulfateAlopecia areata
The present invention relates to alopecia areata treating externally applied medicine preparation, and is especially preparation process of minoxidil solution and minoxidil liniment sheet. The minoxidil solution is prepared with minoxidil, 1, 2-propylene glycol, ethanol, sodium thiosulfate, tetrabutyl ammonium hydrochloride and water in certain proportion. The preparation process includes dissolving minoxidil in 1, 2-propylene glycol and ethanol solution through heating to 40 deg.c; dissolving sodium thiosulfate and tetrabutyl ammonium hydrochloride in water; and mixing to obtain the minoxidil solution. The minoxidil solution is added to base sheet of water absorbing carrier in surface area of 10-50 sq cm to form the minoxidil liniment sheet, which is sealed in bag for maintenance.
Owner:深圳市天明医药科技开发有限公司
Composition for topical application for preventing hair loss and stimulating hair growth
InactiveUS20140113887A1Preventing hair lossPromotes hair growthOrganic active ingredientsBiocideHair growthHair loss
The present invention relates to a composition for topical application for preventing hair loss and stimulating hair growth having a 5α-reductase suppressant and minoxidil. The composition for topical application for preventing hair loss and stimulating hair growth according to the present invention provides equal or superior hair loss prevention and hair growth stimulation effects while using a much smaller dosage than conventional compositions which use oral 5α-reductase inhibitors and minoxidil alone or together.
Owner:PARK LTD
Topical administration carrier composition and therapeutic formulations comprising same
ActiveUS20070141015A1Reduce evaporative loss of solventBiocideCosmetic preparationsMedicineWhole body
A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents that are susceptible to evaporative loss, when the active ingredient composition is topically applied to the body. The carrier formulation retards the evaporative losses of the solvent component(s) and systemic migration losses of the active ingredient composition, to provide sustained topical action, in relation to formulations lacking the carrier composition of the invention.
Owner:CELMATRIX CORP
Novel compositions of minoxidil
Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising minoxidil, and methods for using the novel compositions for treating and preventing hair loss in a region of a patient.
Owner:麦克尼尔有限公司
Method of enhancing hair growth
InactiveUS20120302588A1Shorten the timeIncrease ratingsOrganic active ingredientsBiocideHair growthHair streams
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include bimatoprost and minoxidil in a vehicle for topical application to the skin of a mammal, e.g. a human, whereby the combination of bimatoprost and minoxidil produces a faster onset of hair growth in humans or other mammals and wherein said composition brings about a synergestic result of faster onset of hair growth as compared to compositions comprising bimatoprost and minoxidil, alone.
Owner:ALLERGAN INC
Novel hair growth composition
InactiveUS20110112125A1Improves transdermal penetrationBiocideCosmetic preparationsWater solubleHair streams
Owner:TRITECH BIOPHARM
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