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74 results about "Bimatoprost" patented technology
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Bimatoprost is used to treat high pressure inside the eye due to glaucoma (open-angle type) or other eye diseases (e.g., ocular hypertension).
Method of enhancing hair growth
ActiveUS20030147823A1Efficient use ofSimple and safe processBiocideCosmetic preparationsHuman animalDouble bond
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
Owner:ALLERGAN INC
Method of Enhancing Hair Growth
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
Owner:ALLERGAN INC
Method for imparting artificial tan to human skin
The present invention relates to novel pharmaceutical compositions of bimatoprost and other cyclopentane(ene) heptan(en)oic acid amides and their use in preventing sunburn and / or providing an artificial tan to human skin.
Owner:ALLERGAN INC
Kit and composition for eyelash growth
The invention provides a kit for enhancing the appearance of eyelashes, comprising an eyelash enhancing composition and delivery system. The eyelash enhancing composition comprises an effective amount of 0.03% bimatoprost. The delivery system comprises a plurality of applicator brushes designed to deliver a fraction of 1-drop bimatoprost dose to the target area.
Owner:ALLERGAN INC
Compositions and methods for hair growth
InactiveUS20120129789A1Promote growthPrevent graying of hair or loss of melanin or pigmentOrganic active ingredientsCosmetic preparationsHair growthScalp
The present invention is directed to compositions and methods comprising the use of bimatoprost and cyclosporine, used concurrently and in combination, to grow hair and for the treatment of all types of hair loss conditions such as but not limited to alopecia areata. The present invention is also directed to compositions containing bimatoprost and cyclosporine A to grow hair on the scalp and other areas of the body and methods of administration of the compositions.
Owner:YOELIN STEVEN
Ophthalmic emulsions containing prostaglandins
ActiveUS8273362B2Good chemical stabilityToxic reductionAntibacterial agentsPowder deliveryNon ionicChemical stability
Cationic ophthalmic oil-in-water type emulsions, include colloid particles having an oily core surrounded by an interfacial film, the emulsion including at least one cationic agent and at least one non ionic surfactant, the oily core including a prostaglandin selected from the group comprising in particular latanoprost, unoprostone isopropyl, travoprost, bimatoprost, tafluprost, 8-isoprostaglandinE2, or a mixture thereof, for treating ocular hypertension and / or glaucoma. These emulsions have the property to increase the chemical stability of prostaglandins.
Owner:SANTEN SAS
Ester Derivatives of Bimatoprost Compositions and Methods
Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
Owner:ALLERGAN INC
Method of enhancing hair growth
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
Owner:ALLERGAN INC
Topical bimatoprost for promoting hair growth containing formulations
InactiveUS20160136071A1Promote and enhance hair growthCosmetic preparationsOrganic active ingredientsProstaglandin analogHair streams
Bimatoprost, a prostamide F2 alpha analog, used alone or in combination with other prostamides, or prostaglandin analogs, in a topical manner for the promotion of hair growth in mustache, beard, chest and other androgen dependent hair growth areas in humans and animals.
Owner:CORBOY JR EDWARD DUNNE
Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
InactiveUS8758733B2Preventing loss of eyelashReduce incidenceCosmetic preparationsBiocideHypotrichosisEyelash
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of compositions comprising bimatoprost for the treatment of post-chemotherapeutic hypotrichosis which may be applied before, during and after receiving chemotherapeutic treatment.
Owner:ALLERGAN INC
Intraocular pressure reduction with intracameral bimatoprost implants
ActiveUS8673341B2Lower eye pressureSustained reduction in IOPSenses disorderEye implantsSchlemm's canalIntraocular pressure
The present invention provides a method of treating an ocular condition in an eye of a patient, comprising the step of placing a biodegradable intraocular implant in an eye of the patient, the implant comprising a prostamide and a biodegradable polymer matrix that releases drug at a rate effective to sustain release of an amount of the prostamide from the implant to provide an amount of the prostamide effective to prevent or reduce a symptom of an ocular condition of the eye, wherein said ocular condition is elevated IOP and said implant is placed in an intracameral location to dilate the outflow channels of the eye emanating from Schlemm's Canal.
Owner:ALLERGAN INC
Compositions and methods for hair growth
InactiveUS20150164765A1Promote growthPrevent graying of hair or loss of melanin or pigmentCosmetic preparationsOrganic active ingredientsHair streamsHair growth
The present invention is directed to compositions and methods comprising the use of bimatoprost and cyclosporine, used concurrently and in combination, to grow hair and for the treatment of all types of hair loss conditions such as but not limited toalopecia areata. The present invention is also directed to compositions containing bimatoprost and cyclosporine A to grow hair on the scalp and other areas of the body and methods of administration of the compositions.
Owner:ALLERGAN INC
Crystalline form of bimatoprost, preparation method and use thereof
ActiveUS20120270946A1Improve stabilityReduce energy consumptionBiocideSenses disorderPowder diffractionBimatoprost
The crystalline form A of Bimatoprost of formula I, its preparation method and use are provided. There are characteristic peaks where diffraction angles 2θ are 3.2+0.2°, 5.5+0.2°, 11.4+0.2°, 16.7+0.2°, 17.6+0.2°, 19.9+0.2°, 20.8±02° and 22.8+0.2° in the X-ray powder diffraction pattern of the crystalline form A.
Owner:SHANGHAI TECHWELL BIOPHARMACEUTICALS CO LTD
Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide f2 alpha agonists
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of compositions comprising bimatoprost for the treatment of post-chemotherapeutic hypotrichosis which may be applied before, during and after receiving chemotherapeutic treatment.
Owner:ALLERGAN INC
Process for the Production of Prostaglandins and Prostaglandin Analogs
The present invention relates to an improved process for the production of prostaglandins and prostaglandin analogs. In particular, this invention relates to the production of prostaglandins of the PGF2α-series, including latanoprost, travoprost, and bimatoprost, which are active pharmaceutical ingredients used for the reduction of elevated intra-ocular pressure in patients with glaucoma and ocular hypertension.
Owner:SANDOZ AG
Fixed dose combination of bimatoprost and brimonidine
InactiveUS20130023536A1Improve their wellbeingRelieve symptomsBiocideSenses disorderBrimonidineTreatment glaucoma
The present invention is directed to compositions comprising combinations of brimonidine and bimatoprost useful for lowering intraocular pressure in a patient and for the treatment of glaucoma
Owner:ALLERGAN INC
Method of enhancing hair growth
InactiveUS20120302588A1Shorten the timeIncrease ratingsOrganic active ingredientsBiocideHair growthHair streams
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include bimatoprost and minoxidil in a vehicle for topical application to the skin of a mammal, e.g. a human, whereby the combination of bimatoprost and minoxidil produces a faster onset of hair growth in humans or other mammals and wherein said composition brings about a synergestic result of faster onset of hair growth as compared to compositions comprising bimatoprost and minoxidil, alone.
Owner:ALLERGAN INC
Topical compositions comprising bimatoprost and methods for stimulating hair growth therewith
Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent the presence or absence of a double bond which can be in the cis or trans configuration and A, B, Z, X, R1 and R2 are as defined in the specification and a penetration enhancer. Such compositions are used in stimulating hair growth of human or non-human animals.
Owner:ALLERGAN INC
7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof
The present invention provides a new crystalline form of bimatoprost, designated as crystalline form II. This new crystalline form is the most stable form known to date of bimatoprost. Moreover, it has been found that bimatoprost crystalline form II is readily prepared from crystalline form I.![7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof](https://images-eureka.patsnap.com/patent_img/9b7308d9-acf6-4174-97f1-b1ffba39606a/US08629185-20140114-D00001.png "7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof")
![7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof](https://images-eureka.patsnap.com/patent_img/9b7308d9-acf6-4174-97f1-b1ffba39606a/US08629185-20140114-D00002.png "7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof")
![7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof](https://images-eureka.patsnap.com/patent_img/9b7308d9-acf6-4174-97f1-b1ffba39606a/US08629185-20140114-D00003.png "7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-N-ethyl-hept-5-enamide (bimatoprost) in crystalline form II, methods for preparation, and methods for use thereof")
Owner:ALLERGAN INC
Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of compositions comprising bimatoprost for the treatment of post-chemotherapeutic hypotrichosis which may be applied before, during and after receiving chemotherapeutic treatment.
Owner:ALLERGAN INC
Improved process for the production of bimatoprost
InactiveUS20110178340A1Long reaction timeHigh yieldOrganic compound preparationCarboxylic acid amide separation/purificationAlcoholSolvent
The present invention relates to a process for the purification of crude bimatoprost to obtain pure bimatoprost comprising a chromatography, preferably a chromatography using an achiral stationary phase and an eluent comprising an alcohol and an apolar solvent; and crystallisation of the product obtained the chromatography to obtain pure bimatoprost.
Owner:SANDOZ AG
Process for the preparation of prostaglandin derivatives
InactiveUS20120016136A1Silicon organic compoundsOrganic compound preparationProstaglandin F2alphaMedicinal chemistry
The invention concerns a new process for the preparation of prostaglandin derivatives, in particular prostaglandin F2α derivatives, for example bimatoprost, latanoprost and travoprost, the new intermediates of said process and their use in the preparation of prostagblandin derivatives.
Owner:SIFAVITOR
Process for the production of intermediates for making prostaglandin derivatives such as latanaprost, travaprost, and bimatoprost
The subject matter of the invention is directed to a chemical process, namely, a process for the production of an intermediate compound used to make the pharmaceutical compound such as latanoprost.
Owner:EASTAR CHEM CORP +1
Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide f2 alpha agonists
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of compositions comprising bimatoprost for the treatment of post-chemotherapeutic hypotrichosis which may be applied before, during and after receiving chemotherapeutic treatment.
Owner:ALLERGAN INC
Bimatoprost eye drops and preparation method thereof
ActiveCN102716074AReasonable preparation processEasy to operateOrganic active ingredientsSenses disorderSolubilityMedicine
The invention discloses a bimatoprost composition. The composition comprises an effective treatment dose of bimatoprost, non-ionic surfactant and a pharmaceutically acceptable carrier; the invention also provides a preparation method for the bimatoprost composition; and by the bimatoprost composition, the problem of low dissolubility of bimatoprost in the preparation process can be solved, the stability of bimatoprost at high temperature is improved, and the forming of relative substances is reduced.
Owner:WUHAN WUYAO SCI & TECH
Crystalline forms of bimatoprost acid, methods for preparation, and methods for use thereof
The invention provides new crystalline forms of 7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid. This compound is commonly referred to as “bimatoprost acid.” The novel crystalline forms are designated forms I, II, and III. The invention crystalline forms are useful for solid ocular implant formulations, utilized in the treatment of various ocular conditions, such as, for example, ocular hypertension. In addition, invention crystalline forms are useful for solid or semisolid dosage formulations used to treat ocular hypertension.
Owner:ALLERGAN INC
Bimatoprost Ocular Silicone Inserts and Methods of Use Thereof
The present invention is directed to compositions of bimatoprost, processes of preparing these compositions, devices comprising these compositions, and methods of lowering intraocular pressure.
Owner:FORSIGHT VISION5 INC
Drippable opthalmic bimatoprost gel
ActiveUS10314780B2Extended retention timeImprove efficacyOrganic active ingredientsSenses disorderCellulosePolyvinyl alcohol
The invention refers to a drippable ophthalmic gel, said gel having composition comprising bimatoprost in an amount of 0.003 to 0.03% by weight, polyacrylate in an amount of >0.2% by weight, povidone (PVP), dextrane, polyethylene glycols (PEG), carboxymethyl cellulose (CMC) or poly(vinyl alcohol) (PVA) in an amount of 0.2 to 10% by weight, an isotonizing agent in an amount to produce an osmolality of 200 to 400 mosml / kg, a salt for adjusting the viscosity in an amount of 0.05 to 0.4% by weight, a base in an amount to adjust the pH to 6 to 8 and excipients normally used in ophthalmic gels, having a viscosity in the range of 200 to 2000 mPa·s.
Owner:MEDPROJECT PHARMA ENTWICKLUNGS UND VERTRIEBSMBH
Enzymatic transformation of a prostaglandin (bimatoprost) intermediate
A method for the selective enzymatic acetylation of a bimatoprost intermediate is provided.
Owner:TEVA PHARM USA INC
Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide f2 alpha agonists
The present invention is directed to compositions and methods for the treatment of post-chemotherapeutic hypotrichosis. More specifically, the present invention is directed to the use of compositions comprising bimatoprost for the treatment of post-chemotherapeutic hypotrichosis which may be applied before, during and after receiving chemotherapeutic treatment.
Owner:ALLERGAN INC
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