309 results about "Absorption (skin)" patented technology

The invention belongs to the technical field of cosmetics, and discloses anti-aging recombinant collagen as well as a preparation method and application thereof. The amino acid sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.1, and the nucleotide sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.2. The recombinant collagen CaI1 is constructed and expressed by recombining the effective sequences of the I-type collagen, the III-type collagen and the XVII-type collagen, and the recombinant collagen CaI1 is free of cytotoxicity, free of hidden danger of endotoxin and good in safety. The skin care product added with the recombinant collagen CaI1 can promote skin collagen absorption, inhibit skin aging and improve skin elasticity, and has a good application prospect.

The invention discloses a control system of an intense pulsed light therapeutic apparatus, which relates to the technical field of therapeutic apparatus control and comprises a dynamic spectral energy adaptation module, a three-dimensional contact pressure field calibration module, a domain gradient temperature management module and a multi-mode safety interlocking module. Through a multispectral sensor and a convolutional neural network, a skin absorption coefficient is dynamically calculated, pulse light parameters are optimized, and accurate energy adaptation is achieved; the uniformity of a contact pressure field is adjusted and calibrated by using a pressure-sensitive matrix and an ANFIS network in combination with a mechanical arm; by means of an annular temperature sensor array and a finite element model, regional temperature monitoring and dynamic adjustment are achieved; and through a multi-stage interlocking mechanism and a multi-dimensional scoring model, the safety and comfort of the treatment process are ensured. The treatment effect, the individuation level and the intelligent degree of the intense pulsed light therapeutic instrument are remarkably improved, and a more efficient and safer solution is provided for clinical application.

The invention relates to the technical field of medical materials, and particularly discloses a biocompatible hydrogel microneedle nursing dressing and a preparation method thereof. A biocompatible hydrogel microneedle nursing dressing comprises a hydrogel substrate, microneedles regularly attached to the side, facing the skin, of the hydrogel substrate, and a breathable film layer attached to the side, back to the skin, of the hydrogel substrate. The micro-needle array tip area of the biocompatible hydrogel micro-needle nursing dressing provides rigid support through silk fibroin, it is ensured that a micro-needle can penetrate through the cuticle, the silk fibroin and hyaluronic acid are compounded through the middle-layer needle body transition area, the mechanical strength and the swelling property are balanced, the flexibility is improved through glycerinum, the needle body is prevented from being broken, and the biocompatibility is improved. The closed area of the top substrate adopts high-concentration hyaluronic acid to achieve rapid water absorption swelling and promote drug diffusion, polydopamine nanoparticles enhance antibacterial property and tissue adhesion, genipin crosslinking improves mechanical strength, and a sealing barrier is formed to prevent drug leakage.

The invention relates to an external composition for hair growth regulation and a preparation method thereof, and belongs to the technical field of cosmetics and medicines. The composition disclosed by the invention comprises nano mesoporous carbon for enhancing permeation, various surface functional modifications on the nano mesoporous carbon, minoxidil, protein fragments, polypeptides, oligopeptides, amino acids, dutasteride, bimatoprost, traditional Chinese medicine extracts, vitamins, caffeine, nucleosides, growth factors and various auxiliary functional components. Wherein the pore diameter of mesopores of the nano mesoporous carbon for enhancing permeation is 2-30 nm, the total pore volume of the mesopores is 1.5-3.5 cm < 3 > / g, and the particle size of the nano mesoporous carbon is 50-200 nm. The prepared nano mesoporous carbon is granular, controllable in size, stable in structure, free of irritation to skin, capable of keeping inert to various active ingredients in the composition, capable of enhancing absorption and permeation of other ingredients on the skin, wide in application range, capable of compounding various types of active ingredients and high in biological safety.

The invention discloses an adapalene external preparation and a preparation method thereof, and relates to the technical field of adapalene preparation preparation. The adapalene gel comprises the following raw materials in percentage by mass: 4.5-7.5% of adapalene, 3.5-8% of a gel base material, 2-4.5% of cellulose, 0.5-2% of a penetration enhancer, 18-25% of a water-retaining agent, 2-5% of a surfactant, a pH value regulator and the balance of water, the dosage of the pH value regulator is based on the standard that the pH value of the adapalene external preparation is regulated to 7-7.5; the gel base material comprises poloxamer or carbomer, and further comprises sa-hao seed gum, and the use amount of the sa-hao seed gum accounts for 25-35% of the total mass of the gel base material. According to the adapalene external preparation provided by the invention, the irritation of adapalene to the skin is basically eliminated by utilizing the effects of the gel base material consisting of poloxamer or carbomer and sa-hao seed gum and the surfactant; the adhesive has good cohesiveness and water-retaining property, can keep the affected part moist after being smeared, promotes medicine absorption, and avoids being wiped off or automatically falling off; the stability is improved, and the medicine slow release time is indirectly prolonged.

The invention relates to an algin sulfate (PMGS) patch as well as a preparation method and application thereof, and belongs to the technical field of medicines. According to the application, the fucoidan polysaccharide sulfate (PMGS) is used as a main raw material of the microneedle for the first time, the needle tip is completely composed of PMGS, the PMGS plays a role in medicine and adjuvant integration, on one hand, the PMGS is used as a needle tip matrix to provide enough mechanical strength to pierce warts and surrounding skin and is more suitable for related warts with obvious skin thickening, and on the other hand, the PMGS is diffused and released at the position where viruses are located, so that the effect of preventing and treating warts is achieved. The skin wart treatment effect is achieved by preventing virus from entering and enhancing skin immunity, compared with a previous authorized patent scheme, the problems that PMGS as macromolecular polysaccharide enters the skin and is insufficient in absorption are solved in a microneedle mode, PMGS can be directly delivered to basal layer cells where HPV is located, and fixed-point drug delivery is achieved.

The invention discloses an essence composition containing lipidosome with an acne removing effect as well as a preparation method and application of the essence composition. The essence composition comprises the following components: 2-30% of lipidosome with the acne removing effect, 0.5-15% of a skin conditioner, 5-40% of a humectant, 0.1-3% of a preservative, 0.15-10% of a thickening agent, 0.05-5% of a chelating agent, 0.01-3% of a pH regulator and deionized water. The lipidosome with the acne removing effect is prepared from the following components in percentage by weight: 1.5 to 2.5 percent of white willow bark extract, 0.3 to 0.7 percent of Pinosine, 2 to 4 percent of rhizoma bletillae root extract, 4 to 6 percent of nicotinamide, 0.15 to 0.35 percent of oligopeptide-3, 7 to 12 percent of lecithin and 1 to 2 percent of cholesterol. In the preparation process, the lipidosome with the acne removal effect is reasonably compounded with other auxiliary material matrixes, so that efficient transmission and absorption of active ingredients can be promoted, irritation to skin can be effectively relieved, meanwhile, the overall effect of the essence is enhanced, the essence has mildness and high efficiency, and the high-efficiency requirement of consumers for the acne removal skin care product is met.

The present invention relates to a bio-based and biodegradable superabsorbent polymer (SAP) comprising sodium alginate, modified cellulose, at least one activation agent, and at least one crosslinking agent. The SAP exhibits a high bio-based content of up to 93% and fulfills industrial composting standards such as EN 13432. The crosslinking reactions are performed under mild conditions, including ambient temperatures and neutral to alkaline pH, eliminating the need for high thermal energy. The resulting SAP granules demonstrate excellent liquid absorption performance, rapid swelling, high retention, and no observed toxicity or skin sensitization. The invention provides a sustainable alternative to petroleum-based SAPs for use in hygiene products, agriculture, and other disposable applications.

The invention discloses a multifunctional face and chest care mask and a preparation method thereof, and belongs to the technical field of beauty and skin care. The mask adopts a split type design, comprises a face membrane and a chest membrane, and realizes six functions of moisturizing, cleaning pores, whitening and brightening, soothing and repairing, controlling oil and removing acnes, and resisting aging and tightening through innovative active component combination and a multi-layer structure. The face membrane comprises an adsorption layer, a slow release layer and a water locking layer; and the chest membrane adopts an elastic fiber substrate and a permeation-promoting microneedle structure, so that the absorption of active ingredients is enhanced. The active ingredients comprise a hyaluronic acid compound, nano-scale bentonite, nicotinamide, a centella asiatica extract, a salicylic acid derivative, collagen polypeptide and the like, and the comprehensive nursing effect is improved through the synergistic effect. The preparation method is combined with electrostatic spinning, micro-capsule wrapping and 3D printing technologies, and precise controlled release and personalized adaptation are achieved.

The invention discloses a plant extract transdermal absorption dynamic regulation and control method based on artificial intelligence. The method comprises the following steps: S1, forming a structured data sequence; s2, generating preliminary prediction data; s3, forming an optimized GRU prediction model; s4, performing real-time prediction on a future transdermal absorption state by utilizing the optimized GRU prediction model, and generating prediction data of an absorption rate, a drug concentration in skin and an accumulated absorption amount; and S5, according to the prediction data and a preset drug release target, carrying out global search and optimization on drug release control parameters through the firefly population optimization algorithm, generating a corresponding dynamic regulation and control instruction, and adjusting the release rate and carrier diffusion characteristics of a drug release device. The release rhythm can be actively adjusted according to the predicted data, so that the concentration stability and the curative effect persistence of the plant active ingredients in the target cortex are ensured.

The invention relates to the technical field of active peptides, and discloses a whitening and anti-wrinkle protein active peptide composition as well as a preparation method and application thereof. The whitening and anti-wrinkle protein active peptide composition is prepared from the following raw materials in parts by weight: 10 to 15 parts of elastin peptide, 11 to 14 parts of fish collagen peptide, 8 to 10 parts of fish maw small-molecule active peptide, 5 to 10 parts of cubilose peptide, 5 to 10 parts of sea cucumber peptide, 2 to 6 parts of Chinese fevervine herb active peptide, 1 to 3 parts of zingiber corianum active peptide and 1 to 5 parts of lycopene. According to the whitening and anti-wrinkle protein active peptide composition and the preparation method and application thereof, small-molecule active peptide in the prepared protein active peptide composition is beneficial to absorption of dermal cells, and meanwhile, through the synergistic effect of multiple active ingredients, the whitening and anti-wrinkle effects are effectively achieved, the skin quality is improved, and aging is delayed.

The invention discloses a sialic acid mild brushing acid composition and application thereof, and relates to the technical field of cosmetics. The sialic acid mild brushing acid composition comprises sialic acid and a solvent, the mass concentration of the sialic acid is 2%-15%, and the solvent is selected from at least one of 1, 3-propylene glycol, butanediol, dipropylene glycol and water. The sialic acid is creatively used as one of the mild brushing acid components, can soften old and waste cutin mildly and promote cutin exfoliation and permeation and absorption of the sialic acid, so that the sialic acid can fully play a skin protection role, has an excellent mild cutin exfoliation effect and has the effects of improving hyperpigmentation and coarse pores; and a dynamic balance skin care strategy of breaking while standing and breaking while standing can be realized. The prepared cosmetics have better moisture retention and safety, repair barriers through moisture retention, improve pigmentation through oxidation resistance, stimulate collagen to remodel a supporting structure to improve coarse pores, and finally consolidate the health state of the skin through immunoregulation.

The invention discloses a high-moisture-permeability hydrogel nursing patch and a preparation method thereof, and belongs to the technical field of medical supplies. Sodium alginate and gelatin are scientifically compounded to serve as a gel skeleton, functional components such as the aloe extract, the humectant and the penetration enhancer are supplemented, a stable three-dimensional network structure is constructed, the synergistic effect of multiple effects of moisturizing, resisting bacteria, promoting absorption of active ingredients and the like is achieved, and the synergistic improvement of high moisture permeability, antibacterial property and mechanical property of the product is achieved; the prepared nursing patch can quickly and largely absorb exudate at a wound, keep the wound clean and dry, reduce the risk of wound infection by absorbing the exudate, promote wound healing, effectively relieve skin surface wounds and scratches, and avoid skin infection and ulceration caused by the wounds.

The invention is suitable for the technical field of bio-photonics, and provides a capillary refilling time self-adaptive measurement system and method, and the system comprises a negative pressure adsorption module, a step release module, a modulation module, a detection module, a demodulation module, a signal processing module and a main control unit. Standardized microcirculation stimulation is realized through negative pressure adsorption and step release; adopting a frequency domain modulation and demodulation technology to obtain the phase and the amplitude of the optical signal, and inverting an absolute absorption coefficient and a reduced scattering coefficient by utilizing a frequency domain diffusion equation; and selecting an absolute absorption coefficient under equal absorption point wavelength as a blood volume index, fitting a recovery curve through a system identification model, and calculating to obtain self-adaptive capillary refilling time. According to the collaborative scheme, the problems that in the prior art, stimulation is not standard, the result is greatly influenced by skin color and temperature, and absolute parameter support is lacked are solved, and objective and accurate measurement which is high in repeatability, cross in skin color and resistant to environmental interference is achieved.

The present invention provides a method for preparing a ceramide cell phospholipid composition by complex coacervation and its application, belonging to the technical field of cosmetics. It solves the technical problems such as low preparation efficiency, high production energy consumption, poor preservation effect, poor moisturizing and whitening and anti-wrinkle effects of existing cosmetics. The formula of the ceramide cell phospholipid composition prepared by complex coacervation in the present invention is reasonable, with a high ceramide content, good product quality, can be stored for a long time, has the effects of promoting the absorption of active substances and reducing skin irritation, can significantly increase the water content of the skin, has a stable and lasting moisturizing effect, has soothing and repairing effects, and enhances the whitening and anti-aging effects; the method for preparing the ceramide cell phospholipid composition by complex coacervation in the present invention is produced by a combined device, and the hot cycle and pipeline production are adopted to ensure the mixing reaction effect, with high preparation efficiency, short production time and low energy consumption.

1. Name of the product in this design: Microneedle Consumables (NH4). 2. Purpose of this design: This design is intended for use with an electric skin care pen, applied to the skin surface to assist in the absorption of skin care essence. 3. The key design features of this product are its overall shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention discloses a skin-friendly organopolysiloxane elastomer material and a preparation method thereof, and relates to the technical field of organosilicon materials. The preparation method of the skin-friendly organopolysiloxane elastomer material at least comprises the following preparation steps: dissolving a hydrophilic modified polysiloxane elastomer in chloroform, pouring into a mold, and drying to obtain a supporting layer; the aloe polysaccharide modified polysiloxane copolymer is dissolved in a tetrahydrofuran / water mixed solvent, the mixture is smeared on the supporting layer, a contact layer is formed after drying, and the skin-friendly organopolysiloxane elastomer material is obtained. The skin-friendly organopolysiloxane elastomer material prepared by the invention has good mechanical properties, air permeability and water absorption, is beneficial to growth and regeneration of wound tissues when being used as a dressing, and accelerates healing of wounds.

The invention discloses a circulating hot compress control method for improving the external application curative effect of Zhuang Yao medicine, and relates to the technical field of circulating hot compress. A double-point thermocouple sensor and an NTC thermistor are cooperatively arranged, and time lag and local temperature dynamic characteristics in the skin heat conduction process are accurately recognized; the delay behavior between surface layer heat absorption and deep layer heat diffusion can be distinguished in detail. By collecting and fitting four thermal behavior parameters of skin temperature rising slope delta pT, thermal response inertia time Tr, local heat conduction delay time Tag and maximum temperature difference delta Tu, a complete characteristic curve of a hot compress start-peak value-lag-attenuation process is established, and multi-dimensional comprehensive description of the skin heat sensitivity state is realized. Through the comprehensive evaluation index phi cyc, the system can accurately identify whether the current hot compress is effective or deviates, so that a definite and quantifiable feedback basis is provided for doctors or users, and the formation of a thermal therapy curative effect file and a data record is facilitated.

The application provides a Guizhou Rhamnus skin wound healing ointment and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions. The ointment comprises Guizhou Rhamnus concentrated extract and base excipients. The ointment has the functions of promoting skin wound healing, preventing swelling and pain, preventing infection and scar, reducing swelling and pain, removing blood stasis and promoting tissue regeneration, dredging channels and activating collaterals, and healthy skin tissue. The active ingredients of traditional Chinese medicine have the advantages of rapid healing and repair, obvious swelling and pain relief, delicate ointment texture, easy absorption by the skin, high safety, good stability, wide source of raw materials, easy collection, simple preparation process, batch processing, no toxic side effects on the health of production personnel, and no adverse effects on the environment.

The invention discloses a novel moxibustion therapy and an application method thereof, and belongs to the technical field of moxibustion therapies.The application method comprises the following steps that firstly, needed moxibustion instruments are prepared and comprise heat insulation cloth, medicine applying cloth, a moxibustion column, a steel needle and traditional Chinese medicine; 2, the fire insulation cloth and the medicine applying cloth are trimmed through scissors; 3, smearing the trimmed cloth with traditional Chinese medicine capable of clearing and activating the channels and collaterals, and then pasting the cloth to a treated acupuncture point. The traditional Chinese medicine powder and ointment with the effects of clearing and activating the channels and collaterals and expelling wind and removing cold are smeared on the medicine smearing cloth and attached to specific acupuncture points, warm stimulation of the moxibustion column is combined, local blood circulation can be enhanced, absorption of medicine components is promoted, and therefore the treatment effect is improved; compared with a traditional sharp needle head, the skin injury risk is reduced, and the treatment safety and comfort are improved.

The invention discloses a human face skin multi-component concentration analysis method and device based on hyperspectral imaging, and relates to the technical field of spectral imaging. The method comprises the following steps: under a standardized condition, sequentially collecting dark background data, standard integrating sphere uniform light field data and standard reflectivity plate reference spectrum data; collecting original face hyperspectral data under the same condition; correcting the original face data and the reference data based on the dark background data and the uniformity correction coefficient, and calculating the reflectivity data of the face skin in combination with the known reflectivity of the standard reflectivity board; establishing correlation between the reflectivity and a tissue absorption coefficient based on a skin optical model, wherein the absorption coefficient is expressed as linear superposition of various target component concentrations and standard spectral characteristics thereof; and solving the relationship by adopting a fitting optimization algorithm to obtain the pixel-level concentration of each component and generate a two-dimensional distribution diagram. By optimizing an acquisition device, a spectral analysis algorithm and a visualization function, high-precision, safe and easy-to-use detection effects are realized.

The embodiment of the application discloses a skin care prompting method and a skin care device. The method comprises the following steps: acquiring a skin image of a region to be cared, the skin image containing skin and hair; determining a hair state index of the region to be cared based on the skin image; and generating first prompting information in the case that the hair state index exceeds a preset index threshold, wherein the first prompting information is used for prompting a user to perform a hair shaving process first. In this way, through the intelligent judgment and prompting mechanism, the user can be actively guided to perform a standard preprocessing when the hair state index exceeds the preset index threshold, so as to avoid skin damage such as burns, erythema and stinging caused by excessive absorption of IPL energy by body hair, excessive heat diffusion and high epidermis temperature, thereby ensuring the safety of skin care operation, enabling more energy to act on hair follicles to improve the skin care effect, and improving the intelligent degree and use experience of the skin care device.

The absorbent article is characterized in that the surface sheet (20) has a skin-side part (21) and a non-skin-side part (22), the average fineness of fibers constituting the non-skin-side part (22) is smaller than the average fineness of fibers constituting the skin-side part (21), the absorbent core (121) has a compressed part (123) compressed from the skin side in the thickness direction, and when a drainage test is performed, the drainage index is 50% or less. In a liquid discharge test, 40 ml of artificial urine is dropped four times at a predetermined position on the surface sheet (20), and then a liquid discharge index related to the absorption rate and the absorption amount of the artificial urine is obtained on the basis of the measurement results of the predetermined position by a moisture meter.

The invention discloses an anti-inflammatory bone-invigorating product containing eucommia ulmoides extract and a preparation process and application thereof, and relates to the technical field of anti-inflammatory product preparation, the anti-inflammatory bone-invigorating product is prepared from the following raw materials: calendula officinalis, chrysanthemum, fructus forsythiae, dandelion, eucommia ulmoides total glycoside extract, ampelopsis grossedentata extract, achyranthes bidentata extract, pholidota chinensis, eclipta alba, prebiotics, a binding agent, a diluent and an auxiliary agent. The medicinal properties of various herbal medicines and other effective components are combined, the texture, stability and usability of the plaster are guaranteed, meanwhile, the extracted eucommia ulmoides total glycoside can improve the inflammation inhibition effect, enhance the resistance of the plaster to bacteria and viruses and prevent skin infection, the permeability of the plaster is improved through the eucommia ulmoides total glycoside, and the treatment effect of the plaster is improved. The absorption of the skin on the medicine components is improved, so that comprehensive and effective anti-inflammatory and antibacterial protection is provided.

This invention discloses a method for extracting high-purity PDRN from salmon testes and its application in improving skin condition, belonging to the field of bioactive ingredient extraction technology. Frozen salmon testis tissue is cleaned of blood vessels and fatty impurities, then cryogenically pulverized at -20~-25℃. The pulverized tissue is added to a pre-treatment dispersion buffer and homogenized under high pressure to obtain a DNA fragmentation solution. The precipitate is then separated by centrifugation. The precipitate is dispersed in a dedicated enzyme digestion buffer, and enzymatic digestion with protease and RNase A is performed to inactivate the enzyme. DNase I is added to the digestion solution for enzymatic cleavage. After the reaction, a stop solution is added to terminate the reaction, and the supernatant is separated by centrifugation. Ethanol is added to the supernatant for precipitation, and centrifugation yields PDRN from salmon testes. This invention, through specific buffer systems and enzymatic digestion conditions, increases the PDRN content by 40~60 kDa, allowing for better absorption and utilization by the skin, improving facial hydration and elasticity, effectively reducing facial wrinkles, and improving facial skin condition. It can be used to prepare functional cosmetics.

The invention belongs to the technical field of cosmetics, and particularly relates to collagen peptide with an anti-aging effect as well as a preparation method and application of the collagen peptide. The amino acid sequence of the collagen peptide is as shown in SEQ ID NO.1, and the nucleotide sequence of the collagen peptide is as shown in SEQ ID NO.2. According to the invention, effective sequences of human III type and XVII type collagen are recombined to construct and express the collagen peptide Sa1, and the collagen peptide Sa1 has obvious antioxidant effect, no cytotoxicity and good safety. The skin care product added with the collagen peptide Sa1 can promote skin collagen absorption and effectively exert the anti-oxidation effect, so that the effects of improving skin elasticity and delaying skin aging are achieved.

The application discloses a high-efficiency absorption whitening and freckle-removing skin care product and a preparation process thereof, and belongs to the technical field of cosmetics. The high-efficiency absorption whitening and freckle-removing skin care product contains the following components in terms of weight parts: 0.1-5 parts of a whitening compound (I), 5-10 parts of cocoyl glucoside, 0.5-1 part of menthol, 5-10 parts of phospholipid, 0.5-1 part of EDTA, 0.1-1 part of hyaluronic acid and 150-200 parts of deionized water. The whitening and freckle-removing skin care product has good antioxidant and tyrosinase enzyme activity inhibiting effects, and can realize the effects of whitening and freckle removal.

The application belongs to the technical field of biological medicine, and particularly relates to a composite material containing a local anesthetic and a preparation method thereof. The composite material containing the local anesthetic comprises the following raw materials in parts by weight: bupivacaine hydrochloride 10-15 parts, a light-heat conversion agent 4-8 parts, delta-cadinene 0.5-1 part, a penetration enhancer 1-3 parts, and glycerol 2-5 parts. The light-heat conversion agent and the bupivacaine hydrochloride are added in combination, so that the discomfort caused by photothermal therapy is relieved. The delta-cadinene and the bupivacaine hydrochloride are combined, so that the analgesic effect is improved, the analgesic time is prolonged, the pain caused by frequent dressing change is avoided, and the toxic side effects caused by the accumulation of blood drug concentration are avoided. In addition, the penetration enhancer composed of egg membrane protein peptide and polylysine is introduced, so that the absorption of the effective components by the skin is further promoted, and the analgesic effect is quickly exerted.

The present invention discloses a method for calculating wormhole growth and skin coefficient during the acidizing pumping process, including calculating the maximum pumping displacement that can be achieved by surface equipment without breaking the reservoir; comparing the maximum pumping displacement that can be achieved by the surface equipment to determine the maximum pumping displacement of the acidizing operation; calculating the acid absorption amount and acid absorption pressure of each discrete section, and iteratively optimizing the actual pumping displacement of the current pumping stage; calculating the wormhole length, total wormhole length, skin coefficient generated by wormhole growth, and skin coefficient of each discrete section of the reservoir after the pumping time of the current stage is completed; optimizing the pumping program of the entire acidizing operation based on the total acid amount of the acidizing operation, and calculating the wormhole development length profile, skin coefficient profile, and acid absorption profile of the entire reservoir after the acidizing operation is completed. The present invention adjusts the acid pumping displacement of the reservoir by reducing the wormhole growth and skin coefficient, and can accurately characterize the heterogeneous profile of wormhole development, skin coefficient, and acid absorption caused by reservoir heterogeneity.

The invention discloses a skin care product bottle cap and a skin care product bottle. The skin care product bottle cap comprises a shell provided with a first end and a second end, the first end is provided with a liquid inlet, and the second end is provided with a liquid outlet to be communicated with the liquid inlet; the smearing piece is arranged at the second end and can smear the skin care product flowing out of the liquid outlet to the face; the massage piece is arranged at the second end, and the massage piece is provided with a connecting end and a massage end exposed out of the shell; and the driving part is in driving connection with the connecting end so as to drive the massage part to move. The skin care product bottle cap is provided with the smearing piece and the massage piece with the drive, the skin care product can be smeared to the skin through the smearing piece, manual smearing is not needed, the skin can be automatically massaged through the massage piece during smearing, and skin absorption is promoted.