42 results about "Absorption (skin)" patented technology

The application belongs to the technical field of biological medicine, and particularly relates to a composite material containing a local anesthetic and a preparation method thereof. The composite material containing the local anesthetic comprises the following raw materials in parts by weight: bupivacaine hydrochloride 10-15 parts, a light-heat conversion agent 4-8 parts, delta-cadinene 0.5-1 part, a penetration enhancer 1-3 parts, and glycerol 2-5 parts. The light-heat conversion agent and the bupivacaine hydrochloride are added in combination, so that the discomfort caused by photothermal therapy is relieved. The delta-cadinene and the bupivacaine hydrochloride are combined, so that the analgesic effect is improved, the analgesic time is prolonged, the pain caused by frequent dressing change is avoided, and the toxic side effects caused by the accumulation of blood drug concentration are avoided. In addition, the penetration enhancer composed of egg membrane protein peptide and polylysine is introduced, so that the absorption of the effective components by the skin is further promoted, and the analgesic effect is quickly exerted.

The application discloses a traditional Chinese medicine body milk and a preparation method thereof. The traditional Chinese medicine body milk comprises the following components by weight: 5-15 parts of traditional Chinese medicine active ingredients derived from an ancient prescription of Danggui Yinzi, 1-3 parts of vitamin E, 0.5-2 parts of ceramide NP with a purity of greater than or equal to 95%, and 0.1-0.5 parts of natural borneol with a purity of greater than or equal to 99%, and the rest is an oil phase matrix, an aqueous phase matrix and an emulsifier. The traditional Chinese medicine active ingredients comprise angelica extract, astragalus polysaccharide, sophoramine and glycyrrhizic flavone, and are obtained by a low-temperature warm extract process at 40-45 DEG C. The preparation method comprises the following steps: raw material pretreatment, warm extract extraction, filtration and purification, precise compounding and fusion, emulsification and molding, and cooling and filling. The product has the advantages that skin irritation is less than 0.3, 24-hour moisturizing power is greater than or equal to 78%, the retention rate of herbal active ingredients is greater than or equal to 83.2%, and absorption is achieved within 5 minutes after smearing, and is specially used for improving the problems of dry skin, itching and difficult healing of wounds caused by blood deficiency and dryness caused by old age and chronic diseases.

This invention belongs to the field of cosmetic technology, specifically relating to a collagen peptide with anti-aging effects, its preparation method, and its application. The amino acid sequence of the collagen peptide is shown in SEQ ID NO.1, and the nucleotide sequence is shown in SEQ ID NO.2. This invention constructs and expresses a collagen peptide Sa1 by recombining the effective sequences of human type III and XVII collagen. This collagen peptide Sa1 exhibits significant antioxidant effects, is non-cytotoxic, and has good safety. Skincare products containing collagen peptide Sa1 can promote the absorption of collagen in the skin, effectively exert antioxidant effects, thereby improving skin elasticity and delaying skin aging.

The utility model discloses a kind of venous hot compress sleeve, including the rectangular block of the sleeve main body made of skin-friendly material, sleeve main body is equipped with heating area, the left side of sleeve main body is equipped with first connecting belt, the right side of sleeve main body is equipped with second connecting belt, corresponding position of first connecting belt and second connecting belt is equipped with detachable connecting piece respectively, the position of first connecting belt close to sleeve main body is equipped with infusion leather strip connecting piece, the position of second connecting belt close to sleeve main body is equipped with elastic tightness area.The utility model can realize temperature controllable and heat preservation to a certain extent, improve hot compress operation convenience and security, not only can help patient expand venous vessel, promote drug absorption, also can relieve pain caused by vasospasm, reduce swelling or induration.

The present application relates to a hydrocolloid composition comprising a block copolymer, a plasticizer, a tackifying resin and a viscous polysaccharide. The hydrocolloid composition can be used to prepare a hydrocolloid dressing with higher liquid absorption and tack retention, and can remove old and worn-out keratin on the surface of the skin, and has excellent exfoliation effect.

The present invention provides an absorbent article comprising an absorbent material containing a superabsorbent polymer, wherein the absorbent material containing the superabsorbent polymer is capable of ensuring sufficient absorption of body fluids. [Solution] The absorbent article 1 comprises a surface sheet 2, a first absorbent 4 disposed on the non-skin side of the surface sheet 2 and composed of an SAP sheet containing a superabsorbent polymer, and a second absorbent 5 disposed on the non-skin side of the first absorbent 4. The absorbent article 1 further comprises an embossed portion formed from the surface sheet 2 toward the first absorbent 4 and reaching at least the non-skin side surface of the first absorbent 4. When the first absorbent 4 is divided into three equal regions in the width direction W, the embossed portion includes a first embossed portion 13 located in the regions at both ends of the width direction W and extending along the longitudinal direction L.

The invention belongs to the field of natural pharmaceutical chemistry and the field of cosmetics, and particularly relates to a skin care composition, a skin care product and application thereof.The skin care composition comprises silymarin, epigallocatechin gallate and quercetin, and the mass ratio of the silymarin to the epigallocatechin gallate to the quercetin is (3-7): (3-10): (1-5). The skin care product comprises the skin care composition, the content of the skin care composition is 0.5-10%, the skin care composition or the skin care product is applied to preparation of the skin care cosmetics, the esterified lecithin is used for encapsulating the silymarin, the epigallocatechin gallate and the quercetin, and sodium hyaluronate is matched, so that the skin care composition or the skin care product can be used for preparing the skin care cosmetics. The problems that flavonoid compounds are difficult to dissolve, permeate and absorb are effectively solved, and meanwhile, the skin care composition and sodium hyaluronate have a synergistic effect, so that the moisturizing, wrinkle removing and aging resisting effects are remarkably improved.

This invention discloses a composition, its preparation method, and its application, relating to the field of cosmetics. It solves the problem of poor compatibility between the active ingredients and the system in existing skincare compositions, resulting in poor absorption. A composition is provided, comprising 0.01-100 parts by weight of a functional component and 2-100 parts by weight of an ionic liquid, wherein the ionic liquid comprises 1-50 parts by weight of amino acids and 1-50 parts by weight of other acidic compounds. A method for preparing the composition is also provided: adding the functional component, the acidic compound, and water to a reaction vessel, heating and stirring; adding the amino acid, stirring and mixing evenly, and evaporating the water from the mixture; or adding the functional component, amino acid, and water to a reaction vessel, heating and stirring; adding the acidic compound, stirring and mixing evenly, and evaporating the water to obtain the composition. An application of this composition is also provided, for use in cosmetics for human skincare. This composition exhibits good compatibility between the active ingredients and the system, resulting in good and gentle effects.

The application discloses application of a compound in preparation of a medicine for treating androgen alopecia, and relates to the technical field of biological medicines. The foreskin mesenchymal stem cell extracellular small vesicle has water-soluble and fat-soluble double-soluble characteristics, can be absorbed through the skin, and is administered in a manner of intravenous administration / mist administration and the like. The foreskin mesenchymal stem cell extracellular small vesicle is used as a carrier to load curcumin, so that the absorption of the curcumin can be effectively improved, the pharmacological effect of the curcumin can be improved, and the targeting and anti-inflammatory efficiency can be improved. Moreover, the compound obtained by loading the foreskin mesenchymal stem cell extracellular small vesicle with curcumin can easily penetrate into the skin, directly acts on the hair follicles damaged by androgen, has a good effect of treating androgen alopecia, and can significantly promote hair regeneration.

The peptides of the present invention exhibit skin-whitening activity by inhibiting the absorption of melanosomes in keratinocytes. Therefore, the peptides of the present invention can be used as active ingredients in medicaments for treating or preventing hyperpigmentation caused by excessive melanosome deposition, or as active ingredients in cosmetics for skin whitening.

This invention discloses a topical patch containing Kaempferia galanga (black ginger) extract and its preparation method. The patch comprises, from the outside in, a non-woven fabric backing layer, a heating pack, a breathable and leak-proof membrane, a plaster layer, and a release liner. The heating pack provides continuous, gentle heat to promote transdermal drug absorption. The plaster layer contains Kaempferia galanga extract and various traditional Chinese medicine extracts. The abdominal patch contains Kaempferia galanga (black ginger), Garcinia cambogia, and Atractylodes lancea, used to improve abdominal metabolism and promote bowel movement; the waist patch focuses on regulating blood circulation in the abdomen; the leg patch contains Kaempferia galanga (black ginger), Clematis chinensis, Clematis armandii, and Achyranthes bidentata, suitable for leg soreness and poor circulation; the arm patch contains Kaempferia galanga (black ginger), Curcuma longa, Luffa cylindrica, and Luffa cylindrica, specifically improving arm metabolism. This invention solves the problems of insufficient penetration and slow onset of action in traditional black ginger topical applications, as well as the skin irritation and easy fall-off of traditional plasters, achieving gentle, convenient, and efficient local metabolic regulation and shaping.

This utility model relates to the field of hygiene care products technology, and discloses a diaper pad, comprising a skin-friendly dry layer, a water-collecting and hydrophobic layer, and a breathable and water-proof layer arranged sequentially from top to bottom. The water-collecting and hydrophobic layer includes a perforated water-permeable support layer with a trapezoidal lower surface and a first absorbent with a trapezoidal upper surface. A truncated ring absorbent is provided between the water-permeable support layer and the first absorbent, and a water-collecting groove structure is formed on the inner side of the truncated ring absorbent. A hydrophobic channel that diffuses outwards is provided between the first absorbent and the truncated ring absorbent. The system allows for rapid urine leakage, minimizes the water-transfer area of ​​the skin-friendly dry layer, increases its softness and dryness, and restores softness and dryness to the water-transfer areas, reducing and preventing bacterial infections caused by a humid environment. The water-collecting and hydrophobic layer creates a central water-collecting area, a lower drainage area, and an edge water-storage area, improving the overall utilization rate of the product. A dual temperature and pressure difference promotes the discharge of hot and humid gases through the breathable and water-proof layer, and the secondary absorption structure of the absorbent ensures that urine is fully absorbed and stored within the absorbent, reducing and preventing backflow.

The utility model discloses a kind of three-dimensional suspension type absorption core structure, relate to sanitary towel technical field, including absorption core, the upper of absorption core is fixedly provided with skin-friendly layer, the bottom of absorption core is glued with bottom film, both are fixed by gluing part adhesion, several vertical main absorption grooves are set in skin-friendly layer surface, the two sides of main absorption groove are communicated with branch absorption groove, several diffusion units are provided in absorption core, several diffusion units are arranged along horizontal or vertical direction, several diffusion units are communicated by elastic connecting band, the end of main absorption groove and branch absorption groove away from skin-friendly layer is all communicated with diffusion unit in the top of absorption core.The three-dimensional suspension type absorption core structure of the utility model can uniformly and efficiently absorb menstrual blood, avoid the occurrence of the situation that due to large amount of menstrual blood causes overflow, use experience is good, especially suitable for night use and sports scene.

The present application relates to a kind of mussel mucin composite gel and its preparation method and purposes, including mussel mucin, bioactive ingredient, material B, biological lubricating material, crosslinking agent, analgesic drug and solvent;The mass ratio of mussel mucin and material B is 3:2~4:1, and material B is polyanion material or amphiphilic polyelectrolyte material.The mussel mucin composite gel of the present application is used as skin filling material injection, and the skin filling material is used for filling and supporting shaping in dermis middle layer, subcutaneous layer or periosteum upper level.The mussel mucin composite gel of the present application has excellent anti-degradation performance, high tissue adhesion performance, low water absorption swelling performance, and stronger tissue combination, can effectively avoid the displacement of gel after injection, can long-term maintain filling volume in dermis middle layer, subcutaneous or periosteum surface, with excellent volume stability.

This invention provides a method for preparing natural nanophases of a Uyghur medicine compound preparation for treating eczema and its application. Based on a patent (CN201911308259.1) for a compound preparation for treating skin inflammation, this method regulates the solvent composition, concentration conditions, and mixing method of the extraction system to form a stable multiphase structure. Further, differential centrifugation is used to achieve directional separation of phases with different particle sizes, thereby obtaining natural nanophases. The obtained natural nanophases enrich the active ingredients in the compound preparation, significantly reduce cytotoxicity, and enhance biocompatibility. Simultaneously, they significantly inhibit NO production and exhibit eczema-related antibacterial activity, improving drug absorption and utilization efficiency, thus demonstrating superior eczema-related biological activity. This method also addresses the issue of the darker color of the product obtained from the original preparation process, improving the acceptability of the preparation and medication adherence.

The application discloses a kind of for skin wound patient's suspension bed nursing pad and method for treating urination and defecation.It relates to the technical field of medical devices for suspension bed, comprising: the base stabilizing layer is detachably connected with the suspension bed by microsuction cup, and one end of the base stabilizing layer is provided with a limiting portion;The dynamic shaping layer is arranged on the limiting portion of the base stabilizing layer, and the dynamic shaping layer is composed of a plurality of independent sealed microcapsules arranged in an array, and each microcapsule is provided with a thixotropic non-newtonian fluid material;The absorption and flow guide layer is arranged above the base stabilizing layer and the dynamic shaping layer.The excrement collecting assembly is arranged on the base stabilizing layer.The application discloses a kind of for skin wound patient's suspension bed nursing pad and method for treating urination and defecation, which prevents sliding on the base stabilizing layer, sets up dynamic shaping layer to actively cooperate with the suspension bed to form a recess at the root of patient's leg for defecation, avoids the movement of patients with large-area burns, and can effectively improve the comfort of patients.

The application belongs to the technical field of medical devices, and discloses a dissolvable microneedle injection device for transdermally delivering oligopeptide to treat skin photoaging, which comprises an outer sleeve, an inner sleeve coaxially arranged in the inner sleeve, an arc-shaped strip mounted on the outer side of the inner sleeve, a water storage sleeve arranged at the top end of the inner sleeve, a flow channel communicated between the inner sleeve and the water storage sleeve, a valve arranged in the inner sleeve, and a water absorption sheet drivingly connected to the bottom end of the inner sleeve. Through the action of the double-stroke push rod mechanism and the collaborative design of the innovative double-stroke push rod mechanism and the whole fluid control circuit, the original two independent steps of "mechanical penetration" and "liquid dissolution" are integrated into a coherent and one-time pushing action, which greatly simplifies the operation process, reduces the requirement for the operation skill of the user, and effectively improves the convenience, reliability and user experience of the treatment.

Disclosed is an apparatus (100) for determining oxygen saturation with skin tone correction. The apparatus includes first (102) and second (104) probes adapted to be disposed on a body portion (106) having first through third absorbers, and configured to emit and detect light signals corresponding to a set of wavelengths. The apparatus further includes processing circuitry (116) coupled to the probes and configured to: determine reflectance and transmittance values based on the detected light signals; determine and rescale first and second sets of absorbance values corresponding to the reflectance and transmittance values; determine first through third coefficients of the first through third absorbers; and determine an oxygen saturation value based on the first and second coefficients such that the oxygen saturation value is corrected for skin and tissue absorption.

The utility model discloses a silicon gel dressing of fast absorption wound exudate relates to dressing technical field. Its technical scheme is: including the substrate layer, the core layer, the silicon gel layer and the release film layer that set gradually, be provided with the opening on the silicon gel layer, the core layer sets up at the opening of silicon gel layer and the edge of core layer is bonded with the edge of opening, makes the core layer by the opening of silicon gel layer exposes, the core layer and the part of silicon gel layer that stretches out the core layer all are bonded on the substrate layer, be provided with a plurality of through -holes on the silicon gel layer. The utility model provides the silicon gel dressing of fast absorption wound exudate, realizes the efficient absorption wound exudate of core layer, and the porous structure of silicon gel layer has the ability of ventilative dampness, reduces skin impregnation and the allergic phenomenon, promotes the paste stability and pasting comfort of dressing, and simple structure design is suitable for large -scale production.

1. Name of the product in this design: Microcrystalline Skin Rejuvenation Infusion Bottle (Spherical). 2. Purpose of this product design: For facial skin care, used in conjunction with skin care solution for microcrystalline infusion to promote the absorption of skin care products; a beauty and skin care tool. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention belongs to the field of biomedical technology, and particularly relates to a gel formulation containing recombinant collagen and its preparation method. The gel formulation containing recombinant collagen comprises the following raw materials in parts by weight: 5-10 parts recombinant collagen, 2-5 parts sodium hyaluronate, 10-17 parts chitosan, 0.3-0.8 parts exudate absorbent, 1-5 parts Spartina alterniflora extract, and 50-70 parts water. The gel formulation of this invention utilizes the combination of Spartina alterniflora extract, chitosan, exudate absorbent, and other components to exert antibacterial, anti-inflammatory, and exudate absorption effects, promoting skin tissue repair and improving the quality of wound healing.

The present disclosure relates to a composition for skin improvement comprising beta-sitosterol and betulin. It was confirmed that the composition has excellent effects of skin-soothing and relieving skin irritation by reducing skin nerve stimulation-inducing factors, increasing the expression of moisturizing-related factors, increasing skin absorption, improving skin permeation, and inhibiting mast cell activity, and thus can be effectively used in cosmetics, quasi-drugs, etc. for skin improvement.

The present application provides a kind of emulsion for improving pet skin problems and its preparation method, it is related to the technical field of traditional Chinese veterinary medicine pharmacy.The emulsion is prepared by emulsification homogenization from traditional Chinese medicine extract, traditional Chinese medicine essential oil, plant fatty acid, emulsifier and water, wherein the traditional Chinese medicine extract is Astragalus and ginseng extract, and the traditional Chinese medicine essential oil is a compound of clove basil oil, angelica oil, rose oil and kempas seed oil.The present application solves the problems of large irritability, easy drug resistance of chemical drugs and poor absorption of traditional Chinese medicine by synergistic compounding of active ingredients.The product has the functions of antibacterial, barrier repair, sebum regulation and moisturizing, and the inhibition zone diameters of staphylococcus aureus and malassezia are 12.5±0.5 mm and 10.2±0.3 mm respectively, and it can significantly improve skin moisturizing function, and is mild and non-irritating, suitable for the treatment and care of various skin problems of pets.

The present application relates to the technical field of medical devices, in particular to a continuous skin external medicine coating device, comprising a medicine storage box for loading medicine liquid, the bottom of the medicine storage box is fixedly connected with a driving box; the bottom of the driving box is provided with a medicine coating assembly; the medicine coating assembly comprises a bottom plate fixedly connected to the bottom of the driving box, a medicine coating roller shaft is arranged on the bottom plate, and a driving assembly for driving the medicine coating roller shaft to oscillate and coat medicine is arranged in the driving box; an expansion piece is arranged on the side wall of the bottom plate, a massage roller shaft is arranged at one end of the expansion piece, and a massage assembly for driving the massage roller shaft to massage the skin is arranged on the bottom plate. The present application is used for continuous and uniform coating of skin external medicine, and integrates massage for absorption promotion, medicine liquid quantitative delivery and self-disinfection function, so as to improve medicine coating standardization, medicine efficacy utilization rate and use safety.

This invention relates to the field of medical nursing equipment technology, specifically to a wound and stoma infection prevention and care device. It includes a bag body with an adhesive-coated base fixedly connected to it. The base has a slit in its center, and an annular cavity is fixedly connected to the side of the base closest to the skin. The wall of the annular cavity is made of silicone, and several through holes are formed in the inner wall of the annular cavity. Antibacterial medication is placed inside the annular cavity. An absorption component is provided on the base to assist in absorbing exudate and reduce the risk of infection. This invention, by setting a silicone annular cavity containing antibacterial medication on the skin side of the base, in conjunction with the absorbent resin strip component inside the base, achieves targeted release of antibacterial medication for sterilization and active absorption and transfer of exudate, thus reducing the risk of stoma infection through a dual effect.

A method for improving the effectiveness and reducing the irritation of retinol application by introducing a two-step evening skincare regimen, referred to as “Retinol Staging.” The method includes cleansing the skin and applying a moisturizer in the early evening to enhance hydration and barrier function, followed by a waiting period to allow absorption. Retinol is then applied at bedtime to maximize efficacy and minimize side effects. This approach differs from existing methods like “retinol sandwiching” and “skin cycling,” offering superior hydration and skin barrier protection.

The utility model discloses a wave formula protection pad, including bottom layer, surface layer, flow guide layer and absorption core body, absorption core body is wrapped between bottom layer and surface layer, and the edge position of absorption core body is fixed with bottom layer and surface layer, flow guide layer covers the surface of absorption core body, the surface fixed of surface layer has the skin layer of being close to, the middle part of skin layer of being close to is provided with exposure groove, and the local surface layer is exposed in exposure groove, the product uses the skin layer and the skin contact of pudendal part, and the contact area is relatively smaller, and the position of exposing vaginal orifice, and the small gap is kept between vaginal orifice and surface layer, does not influence secretion and menstrual blood absorption, increases the air permeability simultaneously, when the product uses, is more dry and comfortable.

A system for the non-invasive, continuous determination of blood glucose concentration, comprising: a housing structure configured to come into contact with the skin surface of a subject; a plurality of luminescent elements arranged within the housing structure, each luminescent element configured to emit optical radiation at a specific wavelength from the visible, near-infrared, and short-wave infrared spectral ranges; a control unit electrically connected to the numerous luminescent elements and configured to control the sequential or simultaneous emission of the optical radiation; a photodetection arrangement comprising at least one photodetector positioned to receive optical signals reflected from or transmitted through a tissue area;a signal acquisition unit configured to convert the received optical signals into digitized intensity data corresponding to each emitted wavelength; a preprocessing unit configured to perform normalization, ambient light correction, and motion artifact suppression on the digitized intensity data; a spectral decomposition unit configured to separate the composite optical absorption contributions of multiple tissue components and extract glucose-correlated spectral features; a processing unit configured to estimate blood glucose concentration by correlating the extracted spectral features with a stored computational model;and a calibration unit configured to dynamically update the parameters of the computational model based on temporal fluctuations and subject-specific characteristics, the system being configured to enable continuous and real-time glucose determination without the need for invasive sample collection.