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64 results about "Skin sensitivity" patented technology

Repair compositions and uses thereof

The invention provides a repairing composition and application thereof. The repairing composition at least comprises the following components: (1) polydeoxyribonucleotide; (2) gamma-polyglutamic acid or a salt thereof; and (3) hyaluronic acid or salts thereof, and the three components of polydeoxyribonucleotide, gamma-polyglutamic acid or salts thereof and hyaluronic acid or salts thereof in the repairing composition are compounded to achieve a synergistic effect, so that the repairing composition is beneficial to improving skin sensitivity, repairing skin barriers, stimulating collagen regeneration and the like.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

Polydeoxyribonucleotide salt as well as preparation method and application thereof

The invention discloses a poly-deoxyribonucleotide salt and a preparation method and application thereof, the content of the poly-deoxyribonucleotide salt is greater than 95%, the protein content is less than 1.0%, and after high-pressure moist heat sterilization, the dynamic viscosity reduction amount does not exceed 25%, and the elastic index G'reduction amount does not exceed 30%. The polydeoxyribonucleotide salt disclosed by the invention is simple in preparation process, short in production period, low in cost and suitable for large-scale industrial production; and the preparation process is mild, few impurities are introduced, the product structure is less damaged, and the preparation method is environment-friendly. The polydeoxyribonucleotide salt disclosed by the invention has good physical support performance, has the effects of promoting skin cell repair, resisting skin sensitivity, whitening, resisting inflammation, preventing alopecia and growing hair, and has a wide market prospect.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

Preparation method and application of sensitive skin repairing composition containing phellinus linteus PDRN

The invention relates to a preparation method and application of a sensitive skin repairing composition containing phellinus igniarius PDRN, and belongs to the technical field of cosmetics. The sensitive skin repairing composition is prepared from phellinus medicinus PDRN, bio-saccharide gum-1 and tephrosia esculenta seed extract, and the three components have a synergistic effect and can effectively promote the generation of three barrier proteins, namely tight junction protein, biaprylin and fibroin, so that the skin barrier function is strengthened, the long-acting repairing of sensitive skin is realized, and the skin sensitivity is reduced.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Preparation method and application of natural mild non-irritant soothing composition

The invention relates to skin care products, in particular to a preparation method and application of a natural, mild and non-irritant soothing composition. The invention relates to a natural mild non-irritant soothing composition, which is prepared from the following components in parts by weight: 10 to 50 parts of polyhydric alcohol, 0.025 to 2.5 parts of kava pepper root extract, 0.1 to 10 parts of swertia bimaculata extract, 0.1 to 10 parts of licochalcone A, 0.2 to 2 parts of 1, 2-hexanediol and 0.2 to 2 parts of p-hydroxyacetophenone. The invention proves that the soothing composition composed of the kava pepper root extract, the swertia extract and the licochalcone A can quickly and effectively solve the technical problems in the prior art, and the soothing effect of the soothing composition is verified from three common skin sensitivity problems of stabbing pain, pruritus and redness.
Owner:GUANGZHOU SHIKA TECH CO LTD

Stress-relieving composition containing camellia extract and application of stress-relieving composition

The invention relates to the technical field of skin care products, in particular to a stress relieving composition containing camellia flower extract and application of the stress relieving composition. The composition comprises the following components: a camellia extract, a porphyridium extract, an anise leaf extract and a vetiver extract, and the four components cooperate to regulate and control, completely intervene in a neuroinflammation path, block transmission of nerve stimulation signals, reduce release of neuropeptides and inflammatory factors, repair damaged nerve barriers and improve neurological function. The effect of comprehensively relieving the skin sensitivity reaction is achieved. The composition not only has a faster and more durable effect, but also has good safety and applicability, and is especially suitable for protecting and conditioning high-sensitivity skin and skin in an extreme environment.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Nano-emulsion based on citrus extract and preparation method of nano-emulsion

The invention discloses a nanometer emulsion based on a citrus extract and a preparation method of the nanometer emulsion. The nano-emulsion takes citrus pectin as a main chain, gallic acid, ascorbic acid-phosphate and oleic acid are sequentially grafted, the oleic acid is lipophilic, the rest is hydrophilic, and the amphiphilic pectin can form the whitening nano-emulsion which can be stably stored for a long time. The natural citrus extract is used for replacing traditional synthetic components, has the anti-oxidation, whitening and anti-inflammatory effects, can reduce the skin sensitivity risk, and conforms to the green beauty makeup trend; meanwhile, the oil phase is anchored by a hydrophobic block, steric hindrance is formed by a hydrophilic block, the stability of the emulsion is remarkably improved, and the shelf life is prolonged to 24 months; phenolic acid and ascorbic acid contained in the traditional Chinese medicine composition can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanogenesis and reduce release of a proinflammatory factor IL-6; the composition is low in cost, environment-friendly, suitable for the fields of cosmetics and medicines and wide in market prospect.
Owner:HUBEI ZHONGKANG ZHONGSHENG BIOTECHNOLOGY CO LTD

Wearable health monitoring device, control method thereof and weight change prediction method

The invention discloses a wearable health monitoring device, a control method thereof and a weight change prediction method, and belongs to the technical field of wearable equipment and health monitoring. The wearable health monitoring device comprises a main body, at least five supporting legs, a control module, a data acquisition module and a heating module, an attaching layer is arranged on the side, close to the skin, of the body, the attaching layer is made of a temperature-sensitive material with the viscosity changing along with the temperature, and the control module is used for controlling the heating module to work and adjusting the temperature of the attaching layer, so that the viscosity is adjusted. According to the wearable health monitoring device, dynamic viscosity adjustment can be achieved, wearing stability and comfort are both considered, the problem of skin sensitivity caused by long-term use of a traditional gel patch is avoided, collaborative analysis can be conducted on multi-dimensional physiological data such as the skin moisture content and the body fat layer thickness, and the weight change can be accurately speculated.
Owner:NANJING NORMAL UNIVERSITY

Equipment for assisting in relieving depression and insomnia of teenagers through traditional Chinese medicine acupoint application and control method

The invention discloses a device for assisting in relieving depression and insomnia of teenagers through traditional Chinese medicine acupoint application, the device comprises a flexible application module, an intelligent control system and a wearable monitoring system, the intelligent control system comprises a slow-release adjusting module, a Bluetooth module and a timing setting module, the slow-release adjusting module is used for controlling a micro-fluidic chip to release medicine, and the Bluetooth module is used for controlling the micro-fluidic chip to release medicine; the Bluetooth module is used for interconnection control with a user mobile phone APP, the timing setting module controls the micro-fluidic chips at different positions to release drugs in different time periods based on the user mobile phone APP, and the wearable monitoring system is composed of a wearable bracelet and a sensor; by designing the flexible application module which intelligently controls the effect of applying to the specific acupuncture points of the human body, the medicine application time and dosage can be automatically controlled, the transdermal efficiency of traditional Chinese medicine ingredients is improved through the physical infiltration promotion technology in cooperation with the microneedle array, and meanwhile the skin sensitivity of teenagers is prevented from being damaged by adopting a low-sensitization adhesive; and the device can realize intelligent adjustment of medicine application, and realizes personalized assistance of slow depression and insomnia symptoms.
Owner:AFFILIATED HOSPITAL OF ZUNYI UNIV

Cleaning mud mask capable of clearing pores and preparation method of cleaning mud mask

The invention discloses a pore cleaning mud mask and a preparation method thereof, belongs to the technical field of cosmetics, and particularly relates to a pore cleaning mud mask. Comprising 14 to 18 parts of kaolin, 7 to 9 parts of Manny root ice river mud, 4.5 to 5.5 parts of Amazon white mud, 10 to 12 parts of wheat germ oil, 43 to 47 parts of tea water, 0.1 to 0.14 part of a phellinus linteus extract, 1 to 2 parts of swertia mileensis powder, 2 to 4 parts of lactobionic acid, 0.08 to 0.12 part of salicylic acid and 0.4 to 0.6 part of gluconolactone. The pore cleaning mud mask provided by the invention is uniform in particle size distribution, uniform in mixing and capable of keeping the state of the mud mask moist and not dry in the use process, the cleaning strength of controlling oil, dredging pores and resisting inflammation is improved, meanwhile, skin sensitivity caused by excessive cleaning is avoided, and the cleaning effect is good. The invention provides a novel cleaning mud mask formula for realizing the goal of cleaning pores and an efficient and stable preparation method of the novel cleaning mud mask formula.
Owner:BEAUTIFUL LINK (GUANGDONG) BIOTECHNOLOGY CO LTD

Application of circium japonicum extract

The invention discloses application of a circium japonicum extract. The circium japonicum extract is applied to preparation of products for preventing skin problems caused by cortisol unbalance. The invention also relates to application in preparation of products for relieving skin problems caused by cortisol imbalance. The circium japonicum extract can improve skin problems caused by excessive transformation of cortisol and increase the expression quantity of dermal collagen, skin barrier related protein and skin basement membrane related protein, so that the problems of skin barrier damage, skin sensitivity, wrinkle generation, skin elasticity reduction and the like caused by emotional pressure are effectively relieved.
Owner:上海致臻志臣科技有限公司

Double-resistance anti-allergy composition, double-resistance anti-allergy skin care product and preparation method of double-resistance anti-allergy composition

The invention relates to the technical field of skin care products, in particular to a double-resistance anti-allergy composition in a skin care product and a preparation method of the skin care product. According to the double-resistance anti-allergy composition provided by the invention, the radix gentianae extract has the effects of resisting allergy, repairing, inhibiting skin redness and fever and effectively relieving skin pricking and burning, and the multi-plant soothing repairing agent can repair damaged skin, prevent and inhibit generation of inflammatory factors, quickly relieve itching, remove redness, resist allergy and relieve skin. The traditional Chinese medicine composition can effectively relieve skin pricking and burning feelings and relieve itching and has the effects of immediate analgesia and sedation, and the multiple plant relieving and repairing agents and the gentian plant extract can play a synergistic role to relieve skin sensitivity, redness, pain and burning feelings, relieve itching and the like. The double-resistance anti-allergy composition provided by the invention has obvious red fading and itching relieving effects in a skin care product with an optimal ratio. The preparation method of the anti-allergy, redness-removing and itching-relieving skin care product, provided by the invention, is simple, stable in process and easy to popularize.
Owner:ZHUHAI CENTURY KANGMEI BIOTECHNOLOGY CO LTD

Noctilucent kinesio bandage as well as preparation method and application thereof

The invention discloses a noctilucent kinesio bandage and a preparation method and application thereof.The noctilucent kinesio bandage comprises a base material, a temperature-sensitive adhesive layer and a noctilucent layer, the temperature-sensitive adhesive layer adheres to one side of the base material, and the noctilucent layer adheres to the other side of the base material.The invention relates to the technical field of kinesio stickers. According to the noctilucent kinesio bandage and the preparation method and application thereof, the porous base material is matched with muscle stretching deformation, the sport injury risk is reduced, the nano-silver fiber is used for inhibiting bacteria, the skin sensitivity problem caused by long-time sticking is solved, reliable support is provided for bandage reuse, and titanium dioxide is combined for shielding ultraviolet rays, so that the noctilucent kinesio bandage has a good application prospect. Under the cooperation of the temperature-sensitive adhesive layer, convenient separation between the bandage and the skin is achieved, reliable adhesion support is provided for reuse of the bandage, light of different intensities can be emitted according to the skin surface temperature through the arrangement of the noctilucent layer, and visual and reliable data support is provided for muscle strain caused by movement.
Owner:WUXI LANGYI NEW MATERIAL TECH CO LTD

A nanoemulsion based on citrus extract and a method for its preparation

The application discloses a kind of nanodroplet based on citrus extract and preparation method thereof.The nanodroplet is grafted with gallic acid, ascorbic acid-phosphate and oleic acid in turn with citrus pectin as main chain, and oleic acid is lipophilic, and the rest is hydrophilic, and amphiphilic pectin can form long-term stable storage whitening nanodroplet.The application replaces traditional synthetic ingredients with natural citrus extract, has antioxidant, whitening and anti-inflammatory effects, can reduce the risk of skin sensitivity, and meets the trend of green beauty;At the same time, the hydrophobic block anchors the oil phase, and the hydrophilic segment forms steric hindrance, which significantly improves the stability of the emulsion and prolongs the shelf life to 24 months;The phenolic acid and ascorbic acid contained therein can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanin production and reduce the release of pro-inflammatory factor IL-6;It is low in cost and environmentally friendly, suitable for cosmetics and pharmaceutical field, and has broad market prospect.
Owner:HUBEI ZHONGKANG ZHONGSHENG BIOTECHNOLOGY CO LTD

Anti-pollution composition containing guaiazulene, and preparation method and application thereof

ActiveCN120960065BBiotechnologyLiposome
The present application relates to the technical field of skin care products, and particularly relates to an anti-pollution composition containing guaiazulene and a preparation method and application thereof.The composition is composed of guaiazulene liposomes, kelp extract, date seed extract and schisandra chinensis extract, and achieves triple protection through the cascade effect of the four components.The composition can not only achieve the common effect of "adsorption-anti-inflammation-repair-soothing", but also has considerable soothing effect on skin sensitivity, itching and swelling induced by company decoration.The preparation method of the composition is simple and easy to operate, is conducive to industrialized large-scale production and application, meets market demand, and has strong market application value.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Composition with soothing, red fading and barrier repairing functions and application thereof

The invention discloses a composition with soothing, red fading and barrier repairing functions and application thereof. The composition is prepared from the following raw materials in parts by mass: 0.01 to 0.1 part of fructus hippophae extract, 0.01 to 1 part of flos magnoliae extract and 1 to 5 parts of egg oil. The composition can be applied to cosmetics. The fructus hippophae extract, the flos magnoliae extract and the egg oil are compounded according to a certain mass ratio and then are used as effective components of cosmetics, the composition has the effects of increasing the epidermis moisture content, relieving and fading red and repairing a barrier, and the raw materials of the composition are natural, green, high in safety, mild and non-irritating, and the composition has a good application prospect. The skin care product has good smearing absorption performance, the skin feeling of the skin care product can be effectively improved, the smearing ductility of the product and the softness of the dried skin are improved, and the sticky feeling of the product is reduced; the traditional Chinese medicine composition not only can effectively relieve skin sensitivity and discomfort of adults, but also can be used for relieving eczema, dry and red skin and other problems of infants.
Owner:LIHUA HECHUANG (WUHAN) BIOTECHNOLOGY CO LTD

A composition capable of effectively soothing and repairing sensitive skin, and a preparation method and application thereof

This invention discloses a composition that can effectively soothe and repair sensitive skin, its preparation method, and its application, relating to the field of skincare products. The composition of this invention, by weight, comprises 5-18 parts β-glucan, 1-10 parts mannan, 8-15 parts yeast polypeptides, 1-10 parts sodium hyaluronate, 2-5 parts magnesium ascorbate phosphate, and 8-15 parts Scutellaria baicalensis root extract. This composition is mild and non-irritating, can quickly and effectively relieve skin sensitivity reactions, protect the skin barrier, and has good storage stability, not easily affected by environmental factors such as temperature and oxygen.
Owner:HUNAN TIANGENLE WEIJUN TECH CO LTD

Dynamic power allocation method for a semiconductor epilating device based on spectral analysis

ActiveCN121196718BEngineeringRemoving hair
The application relates to the field of biometric identification technology and discloses a dynamic power distribution method for a semiconductor hair removal device based on spectrum analysis, which comprises the following steps: collecting a laser emission curve and a laser reflection curve of the semiconductor hair removal device, and calculating the laser energy values of the emission and reflection; calculating an absorption characteristic index, dividing a high-absorption region and a low-absorption region, calculating skin characteristic values and a skin sensitivity index of the laser emission region, combining the time length of the hair removal treatment of the laser emission region by the semiconductor hair removal device until the collection moment, determining the working power of the semiconductor hair removal device at the next adjacent collection moment of the collection moment, and realizing the dynamic power distribution of the semiconductor hair removal device. The application can adaptively determine the working power of the semiconductor hair removal device matched with the skin condition.
Owner:ZHENGZHOU PINZHENG TECH CO LTD

Skin sensitivity or rash detector

Systems, methods, and devices for determining the condition of a skin surface covered by an adhesive patch. An external device may be configured to be attached to the skin surface via the adhesive patch. A light source of the external device may emit light through the adhesive patch. A photodetector of the device may output a signal indicative of an amount of the light received by the photodetector after passing through the adhesive patch. A controller of the device may determine, based on the signal, a condition of the skin surface covered by the adhesive patch. In some alternative embodiments, the photodetector may instead by in an implantable device, which may convey the signal to the external device. In some other alternative embodiments, the light source may instead be in an implantable device.
Owner:SENSEONICS INC

Dynamic power distribution method for semiconductor depilation equipment based on spectral analysis

The invention relates to the technical field of biological feature recognition, and provides a semiconductor depilation equipment dynamic power distribution method based on spectral analysis, which comprises the following steps: collecting a laser emission curve and a laser reflection curve of semiconductor depilation equipment, and calculating emitted and reflected laser energy values; an absorption characteristic index is calculated, and a high-absorbance area and a low-absorbance area are divided; calculating a skin characteristic value and a skin sensitivity index of the laser emission area; and determining the working power of the semiconductor unhairing equipment at the next adjacent collection moment of the collection moment by combining the unhairing treatment duration of the semiconductor unhairing equipment to the collection moment, so as to realize the dynamic power distribution of the semiconductor unhairing equipment. The working power of the semiconductor depilation equipment matched with the skin condition can be determined in a self-adaptive mode.
Owner:ZHENGZHOU PINZHENG TECH CO LTD

Application of mulberry root bark extract

The invention discloses application of a mulberry root bark extract, and particularly relates to application of the mulberry root bark extract in preparation of a product for improving skin cortisol unbalance caused by pressure stress. The mulberry root bark extract provided by the invention can improve skin problems caused by excessive transformation of cortisol due to pressure stress, and improve the expression quantity of skin collagen, skin barrier related protein and skin basement membrane related protein, so that skin barrier damage, skin sensitivity, skin aging, skin aging and the like caused by emotional pressure are effectively relieved. Wrinkles are generated; the skin elasticity is reduced and the like.
Owner:上海致臻志臣科技有限公司

Skin sensitivity display method, device, electronic device and readable storage medium

The present application is applicable to the field of image processing technology, and provides a method, device, electronic device, and readable storage medium for displaying skin sensitivity. The method includes: obtaining an original image containing a photographed object, and extracting a skin area image of the photographed object from the original image; determining the skin sensitivity corresponding to each pixel point in the skin area image; adjusting the pixel value of each pixel point in the skin area image in the original image according to the skin sensitivity, using the original image after adjusting the pixel value as a sensitivity distribution diagram, and displaying the sensitivity distribution diagram. The technical solution provided by the present application is generated based on the original image by adjusting the pixel value of the pixel point. Therefore, the outline of the skin area is consistent with the original image. By viewing the sensitivity distribution diagram, the sensitivity corresponding to each local area can be determined, thereby improving the display effect.
Owner:HUAWEI TECH CO LTD

Plant extract composition with anti-aging and soothing effects and preparation method thereof

PendingCN121243008ACosmetic preparationsAntipyreticSpilanthesSandalwood oil
The invention belongs to the technical field of cosmetics, and particularly relates to a plant extract composition with anti-aging and soothing effects and a preparation method thereof. The composition is prepared from the following components in parts by mass: 1 to 5 parts of herba portulacae extract, 0.5 to 3 parts of chamomile extract, 0.1 to 1 part of cedar oil, 0.1 to 1 part of sandalwood oil, 2 to 10 parts of boa oil, 0.5 to 3 parts of lavender extract, 0.5 to 2.5 parts of gomphrena globosa extract, 0.3 to 2 parts of magnolia flower extract and 0.5 to 4 parts of rose extract. The composition disclosed by the invention can not only relieve the problem of skin sensitivity from the source, but also effectively delay the skin aging process through a multi-target synergistic mechanism such as oxidation resistance, inflammation resistance, barrier repair, moisturizing, microcirculation promotion and the like, and realizes the dual effects of resisting aging and relieving through a multi-channel synergistic effect.
Owner:HAINAN MEDICAL UNIV +1

Herbal compound anti-wrinkle spot-fading moisturizing mask and preparation method thereof

PendingCN121943683AEnhance synergistic skin care effectsdesensitizationCosmetic preparationsToilet preparationsCelluloseRHODIOLA ROSEA ROOT
The invention discloses a herbal compound anti-wrinkle spot-fading moisturizing mask and a preparation method thereof, and relates to the technical field of cosmetic processing. The herbal compound anti-wrinkle spot-fading moisturizing mask is composed of essence and two-phase permeation antibacterial film cloth, the essence is prepared from a proteoglycan protein peptide nanocomposite, synergistic liposome, a lucid ganoderma extract, a rhodiola rosea extract, a ginseng extract, a semen cuscutae extract, glycerin, hydroxyethyl cellulose, p-hydroxyacetophenone and deionized water. The essence is loaded in the biphasic permeation antibacterial film cloth, fat-soluble and water-soluble active substances in the essence can permeate and immerse into skin through gradient permeation and multistage pore channels, the permeability of the active substances is improved, and under further delivery of nano-particles and lipidosome, the synergistic skin care effect of multiple components is remarkably improved; the anti-wrinkle, freckle-fading and moisturizing effects are effectively improved, and meanwhile, the anti-wrinkle, freckle-fading and moisturizing composition has excellent antibacterial property and can reduce skin sensitivity and inflammatory response.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Skin-nourishing and repairing cleansing oil containing plant bionic sebum and preparation method of skin-nourishing and repairing cleansing oil

PendingCN120983306ACosmetic preparationsMake-upBiotechnologyEthylhexyl palmitate
The invention discloses skin-nourishing and repairing cleansing oil containing plant bionic sebum and a preparation method of the skin-nourishing and repairing cleansing oil, and the cleansing oil is used in the field of cosmetics and comprises the following components in parts by mass: 45-55 parts of synthetic grease, 25-35 parts of vegetable grease, 15-20 parts of a surfactant, 1-5 parts of plant bionic sebum and 0.1-1 part of an antioxidant. The synthetic grease is prepared from 18 to 22 parts of ethylhexyl palmitate, 15 to 20 parts of caprylic / capric triglyceride and 12 to 17 parts of isopropyl myristate. The cleansing oil disclosed by the invention does not contain components such as preservatives, pigments, mineral oil, essence and the like which are easy to cause skin sensitivity, is compounded with a variety of mild surface active substances, can effectively clean without taking away redundant grease, is matched with four natural vegetable oils: corn germ oil, meadowfoam seed oil, olive fruit oil and camellia oil, can nourish skin while removing makeup, and is suitable for people with sensitive skin to use.
Owner:WEISHUO (SHANGHAI) DAILY NECESSITIES CO LTD

Hand-held cold plasma treatment device (COLD JET PRO)

ActiveCN309724430SHair growthBiology
1. The name of the design product: handheld cold plasma treatment instrument (COLDJET PRO). 2. The use of the design product: the design product is used to improve skin fine lines, skin quality and acne, shrink pores, improve skin sensitivity, promote skin care product absorption and scalp hair growth. 3. The design points of the design product: the shape of the product. 4. The picture or photo that best shows the design points: perspective view.
Owner:GUANGZHOU SHIYAN BEAUTY & HAIRDRESSING TECHNOLOGY CO LTD

A liposome-targeted delivery cream containing ectoine and ceramide and its application

A novel liposome-targeted delivery cream containing ectoine and ceramide and its application, mainly used for relieving skin problems such as skin sensitivity, dermatitis, eczema, etc.; the novel liposome combines soybean lecithin, cholesterol, polyethylene glycol-targeting ligand, and the targeting ligand is ectoine to prepare a targeted liposome capable of simultaneously connecting and encapsulating hydrophilic ectoine and hydrophobic ceramide; further added to the cream matrix to develop a novel liposome-targeted delivery cream of compound ectoine combined with ceramide; it has a phospholipid bilayer and is self-closed in structure, can encapsulate ceramide inside the liposome, has good stability, and at the same time stably connects and modifies water-soluble ectoine to prevent its rapid degradation and reduce the drug release rate. Adding it to the cream matrix and directly applying it to the required skin area can achieve targeted transport of the drug in the skin tissue.
Owner:XINYAN BIOTECHNOLOGY (TAIZHOU) CO LTD

Anti-axon director-1 monoclonal antibodies for treatment of endometriosis and associated pain

The present invention relates to the treatment of endometriosis using an anti-axon guiding factor-1 antibody, or an antigen-binding fragment thereof, and the antibody, or a fragment thereof, for use in the treatment of endometriosis. The treatment includes reducing the lesion of endometriosis, in particular the lesion of uterine and / or uterine horn endometriosis. The treatment also includes chronic pelvic pain relief or vaginal hyperalgesia relief. It may also include a reduction in colorectal hyperalgesia developed in endometriosis, an improvement in bladder dysfunction developed in endometriosis, a reduction in skin sensitivity to enhanced thermal and / or mechanical stimulation developed in endometriosis, an improvement in overall health of altered endometriosis.
Owner:НЕТРИ ФАРМА +6

Soothing and repairing skin care composition as well as preparation method and application thereof

PendingCN121845994Apromote migrationrepair damageCosmetic preparationsHair cosmeticsInflammatory factorsPolygonum cuspidatum root extract
The invention discloses a soothing and repairing skin care composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care composition is prepared from the following components in parts by mass: 3 to 7 parts of herba centellae extract, 0.5 to 1 part of radix scutellariae extract, 2 to 4 parts of rhizoma polygoni cuspidati extract, 1 to 3 parts of radix gentianae extract and 15 to 20 parts of rhizoma atractylodis macrocephalae extract. Wherein the rhizoma atractylodis macrocephalae root extract is prepared by adopting a compound fermentation process of rhodotorula glutinis, lactobacillus brewer and lactobacillus paracasei, and active ingredients are richer. Through the synergistic effect of multiple components, the composition can significantly inhibit secretion of inflammatory factors IL-6 and activity of hyaluronidase and promote HaCaT cell migration, has excellent soothing, anti-inflammatory and repairing effects, and can effectively improve the problems of skin sensitivity, dryness and barrier injury.
Owner:SHENZHEN SALINA BIOTECHNOLOGY CO LTD

Composite VC skin whitening and brightening dressing, preparation method thereof and application of cosmetic

PendingCN120324282ACosmetic preparationsToilet preparationsMagnesium Ascorbyl PhosphateAcid derivative
The invention discloses a composite VC skin whitening and brightening dressing, a preparation method thereof and application of cosmetics. The dressing comprises a supporting body and a gel layer located on the surface of the supporting body. The gel layer comprises a first gel sub-layer and a second gel sub-layer which are arranged on the surface of the supporting body in a stacked mode. The first gel sub-layer comprises a first hydrogel base material and an ascorbic acid derivative located in the first hydrogel base material, and the second gel sub-layer comprises a second hydrogel base material and ergothioneine located in the second hydrogel base material. The ascorbic acid derivative comprises at least one of magnesium ascorbyl phosphate, sodium ascorbyl phosphate, 3-o-ethyl ascorbic acid, ascorbic acid polypeptide and ascorbic acid glucoside. Wherein the mass ratio of the ascorbic acid derivative to the ergothioneine is (1-250): 1. The dressing can effectively solve the possible problems of long onset time of ergothioneine and possible skin sensitivity of ascorbic acid derivatives.
Owner:GUANGZHOU PREXIN BIOTECHNOLOGY CO LTD

Application of circium japonicum extract in preparation of cosmetics with instant skin soothing effect

PendingCN121337665ACosmetic preparationsToilet preparationsTraditional medicineIntracellular calcium ion
The invention discloses an application of a circium japonicum extract in preparation of cosmetics with an instant skin soothing effect, and the circium japonicum extract can quickly and remarkably reduce the calcium ion influx level in cells, inhibit the activity of TRPV1 and reduce the content of TRPV1, so that the instant soothing effect is achieved, and discomfort symptoms such as skin sensitivity, redness and stabbing pain are relieved. In addition, the invention further provides that an extracting agent in the preparation process of the circium japonicum extract has an influence effect on the instant relieving effect of the circium japonicum extract, and the instant relieving effect of the circium japonicum extract is optimized by selecting the extracting agent.
Owner:上海致臻志臣科技有限公司 +1