22 results about "Contact dermatitis" patented technology

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

The invention relates to a traditional Chinese medicine external preparation for treating scalp inflammation. The traditional Chinese medicine external preparation is prepared from honeysuckle, radix sophorae flavescentis, fructus kochiae, cortex dictamni, dandelion, radix salviae miltiorrhizae, menthol, borneol and a transdermal enhancer. The preparation plays anti-inflammatory, bacteriostatic and barrier repairing roles through a multi-target synergistic mechanism, and is suitable for scalp inflammatory diseases such as seborrheic dermatitis and contact dermatitis. The preparation maximally retains active ingredients by adopting a specific extraction process, and the transdermal efficiency is improved by combining a triple permeation enhancing technology. The active ingredients reach the treatment concentration in the deep hair follicle. The pH value (5.5-6.0) of the preparation is matched with the weak acid environment of scalp, malassezia is selectively inhibited without damaging effective microbial communities, and the recurrence risk is reduced from the source. A spray, a lotion and a gel are proved to be capable of remarkably relieving erythema pruritus, inhibiting pathogenic bacteria colonization and accelerating cuticle repair, and have no skin irritation.

The invention provides a pancreatitis patient abdomen mirabilite fixing structure, and belongs to the field of medical instruments. Comprising a sealing box body, the interior of the sealing box body is hollow, a notch is formed in the outer surface of the lower end of the sealing box body in a penetrating mode, a cotton bag used for storing mirabilite is arranged on the lower side of the inner surface of the sealing box body, and the outer surface of the lower end of the cotton bag penetrates to the outer side of the sealing box body through the notch; a folding groove is formed in the outer surface of the upper end of the sealing box body in an embedded mode. By arranging the air guide assembly, the mounting hole is communicated with the air guide pipe through the through hole, and one end of the air guide pipe extends to the outer side of the sealing box body, so that air can flow among the air guide pipe, the through hole and the mounting hole, and air circulation can be realized to a certain extent; and therefore, the probability of contact dermatitis caused by the storage bag in the frequent use and application process can be effectively reduced, and the discomfort of the mirabilite fixing device in the use process can be effectively relieved.

The utility model relates to an infusion port application which comprises a fixing patch and a breathable film, the fixing patch comprises a silk screen and a rubber ring, the silk screen is arranged in the middle of the rubber ring, and the breathable film covering the silk screen is arranged on the upper portion of the rubber ring. The utility model has the beneficial effects that effective ventilation gaps can be formed between skins, so that the breathing function of skin pores is not limited, a local high-humidity environment is prevented from being formed on the skins, the adverse reactions of contact dermatitis and itching of a patient are avoided, and the treatment comfort is improved; and meanwhile, the application can reach a conventional service cycle and does not need to be replaced in advance, so that the medical cost is reduced.

The present invention provides a composition comprising 5-aminolevulinic acid or a salt or ester thereof, comprising: (a) an active ingredient selected from 5-aminolevulinic acid or a salt or ester thereof; and (b) an aqueous carrier comprising an analgesic. The 5-aminolevulinic acid or the salt or ester thereof can be used for photodynamic therapy analgesia for more than 20 minutes, so that the clinical treatment cycle can be covered, the pain feeling after photodynamic therapy can be obviously relieved, the photodynamic therapy receiving time of a patient is prolonged, and the medication compliance of the patient is improved. Moreover, the composition provided by the invention can also improve the condition of tissue edema after photodynamic therapy, improve the skin smoothness after photodynamic therapy and shorten the pigmentation time, and meanwhile, compared with a marketed preparation, the composition has a better effect in the aspect of photodynamic therapy of inflammatory diseases (such as psoriasis or contact dermatitis) or acne and the like, and has a good application prospect. The acceptability of the patient to the photodynamic therapy is further improved; and the application scene of the photodynamic therapy is widened.

The invention discloses a natural plant hair dye, and relates to the technical field of cosmetics. The agent II comprises myrrh; the invention also discloses a preparation method of the plant hair dye, which comprises the following steps of: preparing the agent I, decocting the catechu and the deionized water according to the material-liquid ratio of 1: 6-1: 8 until the catechu and the deionized water are completely dissolved, adding the reducing agent, the alkaline agent and the penetrating agent when the catechu is cold, stirring and dissolving, regulating the pH value to 7-9 by using the alkaline agent, and adding the thickening agent, the essence and the balance of the deionized water; in the preparation of the agent II, the material-liquid ratio of myrrh to deionized water is 1: 6-1: 8. The hair dye disclosed by the invention has the effects of relieving and treating head dermatitis, including symptoms of hair dyeing contact dermatitis and seborrheic dermatitis. For the hair with head dermatitis and afraid of further aggravation of inflammation due to hair dyeing, the hair dye can be used for protecting scalp and treating inflammation during hair dyeing.

Contemplated compositions and methods employ betalains for treatment of various conditions, and especially osteoarthritis, sinusitis, contact dermatitis, acne, an allergic condition, reduced mental alertness, reduced physical strength, reduced physical endurance, and / or impaired mood.

The application discloses a hair perming device with a scalp health detection system and a detection method. Through an image processing system integrating a camera array and a processor, quantitative detection and objective analysis of key indicators of the scalp (such as hair grease, dandruff, redness, etc.) can be performed before, during and after hair perming, which completely changes the traditional subjective and rough judgment mode relying on naked eyes and experience and provides scientific data basis. Moreover, through real-time monitoring, the sub-health or risk state (such as inflammation, sensitivity, damage, etc.) of the scalp can be identified in time, and when high risk is detected, the system can automatically issue an alarm or intervention, thereby effectively preventing safety problems such as contact dermatitis, hair follicle damage and aggravated hair loss caused by improper hair perming operation.

A method for manufacturing medicinal fabric that provides enhanced dermatological comfort for the user / patient, especially those with sensitive skin conditions (e.g., acne, contact dermatitis, atopic dermatitis, eczema, psoriasis, rosacea, urticaria, etcetera) including the steps of: (1) selecting a cotton fiber, wherein the cotton fiber is long staple cotton and 100 percent organic; (2) processing the cotton fiber as greige cotton; (3) optionally verifying that the cotton fiber is organic per Global Organic Textile Standards or comparable standards; (4) fermenting or otherwise naturally preparing an herb or plant into a medicinally potent agent / substance and hypoallergenic dyeing agent; (5) using a skin-friendly binding technique, such as binderless dyeing the cotton fiber with the agent / substance via ultrasonic energy or using a technique that similarly uses no irritative chemical binders; (6) selecting a suitable weave type for the specific use / case to reduce mechanical irritation to the user / patient; (7) optionally verifying that the woven cotton fiber has not been contaminated during the manufacturing process through toxicological verification methods; and (8) optionally verifying that the woven cotton fiber passes the standardized dermatological Human Repeat Insult Patch Test.

The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1 / 2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

The invention belongs to the technical field of medicines, and discloses a hydroxime compound derived from an aqueous extract of heads of angelica sinensis, a dehydrated furazan compound of the hydroxime compound, and preparation and application of the hydroxime compound and the dehydrated furazan compound. In particular discloses a hydroxime compound, a dehydrated furazan compound thereof, pharmaceutically acceptable salts of the dehydrated furazan compound and a pharmaceutical composition of the dehydrated furazan compound. The invention also discloses application of the compound in preparation of medicines for treating arthritis, asthma, chronic obstructive pneumonia, pneumonia, cystic fibrosis, diabetes, obesity, hypercholesterolemia, contact dermatitis, psoriasis, atopic dermatitis, stasis dermatitis, seborrheic dermatitis, neurodermatitis and the like, inflammatory enteritis, multiple sclerosis, Parkinson's disease, cardiovascular disease, autoimmune disease, gout and the like. The invention also relates to applications in medicines or health-care products for treating hyperuricemia and cancers. Activity evaluation of a cell model for starting reporter gene expression by using an NF-kappa B reaction element proves that the compound can significantly inhibit NF-kappa B induced transcriptional regulation and is expected to become a therapeutic drug for treating the various diseases.

This invention belongs to the technical field of cosmetics and topical skin preparations, specifically relating to a naturally derived composition and its application in treating and / or preventing skin inflammation in infants and young children. The naturally derived composition provided by this invention includes egg yolk oil, flaxseed oil, and borage seed oil; the mass ratio of the egg yolk oil, flaxseed oil, and borage seed oil is (1~50):(0.1~10):(0.1~10). The composition provided by this invention can synergistically act on the key mechanisms and targets that trigger contact dermatitis in infants and young children, effectively preventing and treating contact dermatitis and maintaining healthy skin. The composition provided by this invention is hormone-free, antibiotic-free, naturally derived, highly safe, mild and non-irritating, and will not induce drug resistance; it can be widely used in cosmetics and topical skin preparations.

The invention discloses an application of betulinic acid 28-O-beta-D-glucoside (BA-6 for short) in preparation of a medicine for preventing and treating skin inflammation. The problems that an existing medicine for treating dermatitis is limited in curative effect, slow in effect taking, multiple in side effect, high in long-term use risk, large in individual difference, high in treatment cost, likely to cause immunoreaction and the like are solved. The invention discloses application of BA-6 in prevention and treatment of atopic dermatitis, contact dermatitis, eczema, rash, psoriasis, lupus erythematosus, papule squamous skin disease, pityriasis rosea, seborrheic dermatitis, pemphigus, celestial abscess, acne, tinea corporis, impetigo, SAPHO syndrome, hidradenitis suppurativa, dermatitis caused by drugs, lichen planus, pityriasis rubra pilaris, vitiligo, prurigo nodularis, dermatitis caused by drugs, and the like for the first time. The traditional Chinese medicine composition can be used for treating skin diseases, systemic sclerosis, hidradenitis suppurativa, granulomatous skin diseases, vitiligo, dermatomyositis, chronic skin itch and alopecia areata, and has the technical progress of obviously improving skin erythema, papule, edema, scale, moss and ulceration symptoms.

The utility model provides a male uses urine receiving bag, belongs to the medical supplies technical field, include: urine bag body, urine receiving part and fixed part, urine receiving part is used for connecting with penis, and fixed part is used for fixing urine receiving bag on patient's body, urine receiving part includes with skin contact surface, diversion layer and with urine bag contact surface, diversion layer sets up and is set up as upper sparse lower dense structure, urine one -way penetration to urine bag contact surface and lock -up through diversion layer, prevent reverse seepage. The utility model discloses through adopt soft, breathable material, improve the symptom such as skin allergy or contact dermatitis, and red, swollen, itchy of penis skin because of not breathable, improve patient's comfort, urine bag itself increase the scale, and it is convenient for medical treatment to observe patient's illness condition according to urine volume.

The present invention includes a method for the use of N-acetylcysteine (NAC), N-acetylcysteine amide (NAC A) or (2R,2R′)-3,3′-disulfanediylbis(2-acetamidopropanamide) (diNACA) for the prevention and treatment of radiation dermatitis, radiation damage to the skin, xeroderma pigmentosa or protect patients with xeroderma pigmentosa from skin damage caused by exposure to the sun or other radiation, bioweapons, chemical burns, heat burns, contact damage caused by friction, contact dermatitis, hypersensitivity reactions and skin wrinkles and dehydration, skin lightening, skin whitening, and / or skin improvement in a human that comprises administering to the human a therapeutically effective amount of NAC, NACA or diNACA.

This invention provides an abdominal Glauber's salt fixation structure for pancreatitis patients, belonging to the field of medical devices. It includes a sealed box body, the interior of which is hollow with a slot extending through its lower outer surface. A cotton bag for storing Glauber's salt is placed on the lower side of the inner surface of the sealed box body, with the lower outer surface of the cotton bag extending through the slot to the outside of the sealed box body. Moisture-absorbing cotton is fixedly connected to the lower outer surface of the sealed box body, and a folding groove is embedded in the upper outer surface of the sealed box body. By incorporating an air-guiding component, the mounting hole is connected to an air-guiding tube through a through-hole, and one end of the air-guiding tube extends to the outside of the sealed box body, allowing air to flow between the air-guiding tube, the through-hole, and the mounting hole. This facilitates air circulation and effectively reduces the likelihood of contact dermatitis caused by the storage bag during frequent application, thereby alleviating discomfort during the use of the Glauber's salt fixation device.

The invention discloses a traditional Chinese medicine composition for preventing and / or treating inflammatory skin diseases and application thereof.The traditional Chinese medicine composition is composed of Sichuan rhizoma coptidis, Sichuan cortex phellodendri, scutellaria baicalensis and betel nuts, the Sichuan cortex phellodendri serves as a monarch drug to clear away heat and dry dampness, purge fire to remove toxin and astringe dampness and heal sores, the Sichuan rhizoma coptidis, the scutellaria baicalensis and the betel nuts serve as ministerial drugs, the Sichuan rhizoma coptidis purges fire to remove toxin and directly fold heat toxin, and the Sichuan cortex phellodendri and the betel nuts serve as monarch drugs. Baikal skullcap root is used for clearing heat, drying dampness, cooling blood and detoxifying, rhizoma coptidis from Sichuan of China and baikal skullcap root are cooperated with monarch drugs to strengthen the effects of eliminating dampness and detoxifying, betel nut is used for promoting the circulation of qi, promoting urination, helping rhizoma coptidis from Sichuan of China, baikal skullcap root and golden cypress to dredge damp evil and relieve swelling and exudation, and the pungent and divergent properties of betel nut can slightly prevent excessive stasis of drug properties, facilitate penetration of drug properties to skin, kill parasites to relieve itching and directly relieve itching caused by insect epidemic. According to the traditional Chinese medicine composition, only four medicines are combined, the composition is simple, all the medicines have a synergistic effect, damp-heat toxin can be attacked by drying, clearing, benefiting and killing, pathogenic factors can be strongly removed, and skin diseases such as acute eczema, impetigo and contact dermatitis can be effectively treated.

The present disclosure relates to topical formulations and methods of treating skin diseases using topical formulations comprising a JAK 1 / 2 inhibitor, which is ruxolitinib, or a pharmaceutically acceptable salt thereof, and an organic amine pH adjusting agent. The skin diseases for treatment include, but are not limited to, psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization. The organic amine pH adjusting agent is a tertiary amine or an alkanol amine.

This utility model relates to the field of surgical thermal insulation technology, specifically to a water-absorbing surgical heating blanket, comprising a main body, a heating layer and a waterproof layer covering the upper surface of the heating layer, and an absorbent layer on the upper surface of the waterproof layer, which can be directly applied to the patient's skin. The waterproof layer is located between the heating layer and the absorbent layer, and the absorbent layer directly contacts the patient, preventing intraoperative fluids from entering the heating layer and affecting its heating function. The heat from the heating layer passes through the waterproof and absorbent layers and acts on the patient, ensuring stable body temperature. The absorbent layer absorbs intraoperative fluids, preventing the accumulation of intraoperative irrigation fluids or body fluids on the upper surface of the waterproof layer, thereby reducing local immersion, mitigating heat loss, avoiding the risk of iatrogenic hypothermia caused by localized low-temperature areas, and preventing the possibility of contact dermatitis caused by prolonged fluid immersion, thus reducing the likelihood of postoperative complications such as skin redness and maceration.

The invention relates to the technical field of medical auxiliary instruments, in particular to an ECMO pipeline anti-slip fixing clamp based on cambered surface attachment, a knee protection binding sleeve, an ankle protection binding sleeve and a pipeline fixing assembly, the knee protection binding sleeve, the ankle protection binding sleeve and the pipeline fixing assembly are connected through an elastic connecting assembly, and according to the ECMO pipeline anti-slip fixing clamp based on cambered surface attachment, the ECMO pipeline anti-slip fixing clamp based on cambered surface attachment is provided with the knee protection binding sleeve, the ankle protection binding sleeve and the pipeline fixing assembly. By means of the medical sponge liner with the thickness of 5-8 mm in the knee pad binding sleeve, the skin-friendly breathable design of the inner-layer medical-grade pure cotton knitted fabric and the medical silica gel covered edges on the edges of the ankle protection binding sleeve placing holes and the through holes, damage to the skin barrier of the lower limbs of a patient due to repeated tearing of fixing materials is avoided, and meanwhile friction compression of the fabric and the binding band to the skin and bones is avoided; the arc-shaped edge of the knee protection binding sleeve is matched with the ankle joint outline of the ankle protection binding sleeve, the knee protection binding sleeve can be attached to the limb curve, the probability of occurrence of skin complications such as contact dermatitis and skin ulceration is effectively reduced, and meanwhile the operation that nursing staff frequently replace fixing materials is reduced.

This invention is a "Bio-Active Therapeutic Skin Cream"; it is a scientifically formulated advanced Bio-Active Therapeutic Matrix, which is primarily composed of active ingredients derived from natural extracts; Organic Cold-Extracted (55599) Oils; Unrefined Shea Butter, Wax (Vitellaria paradoxa) (Cera alba) and Triple-Rendered Beef Tallow. The main benefits of this invention are: - Repairing the skin's natural moisture barrier function; - Treating severe skin dryness (Xerosis): - Itching (Pruritus): For the treatment and prevention of eczema (Atopic / Contact Dermatitis) and seborrheic dermatitis (Cradle Cap / Seborrheic Dermatitis) in children and adults without any side effects in all age groups. The product is an advanced industrial product and manufacturing process that is prepared by cold pressing and a slow infusion method (Cold Extended Infusion) for at least 2 weeks in a low-temperature controlled system to ensure that the active phytochemicals of the plant are fully integrated into the lipid matrix without being broken down or burned.

Provided herein are methods of treating conditions associated with activation or over-activation of mast cells is acute or chronic urticaria, mastocytosis or any subtype of mastocytosis, pseudo-allergy, any form of dermatitis, such as contact or atopic dermatitis, wound healing, rosacea, acne, or psoriasis, food allergy, or irritable bowel syndrome. The method comprises administering a MRGPRD agonist, such as beta alanine, GABA, β-AIBA, or 5-oxoETE to a patient to treat the condition. Topical, enteric, delayed-release, or aerosol dosage forms comprising beta-alanine also are provided.