13 results about "Chronic eczema" patented technology

A method of treating moderate to severe chronic hand eczema in a human patient comprising twice daily administration to the skin of said human patient in need thereof of an acidified aqueous topical composition comprising comprises 20 mg / g delgocitinib on a free base basis or a pharmaceutically acceptable salt.

The invention relates to the technical field of medicines, and particularly discloses a polypeptide Loni-P extracted from traditional Chinese medicine honeysuckle, and the amino acid sequence of the polypeptide Loni-P is SEQ ID No.1. The polypeptide can be prepared from honeysuckle through the steps of ultrasonication, enzymolysis, purification and the like. Experiments show that the inhibition rate of Loni-P to malassezia under the concentration of 2 mu g / mL reaches 86 + / -5.29%, which is similar to that of positive control ketoconazole (92 + / -9.17%). The invention further provides a medicated bath component containing Loni-P. The medicated bath component is composed of polypeptide, beta-cyclodextrin, chitosan, fumaric acid, sodium hydroxide and other auxiliary materials and is matched with 200 L of medicated bath water. Clinical experiments show that the medicated bath can remarkably relieve itching, skin lesion area and shape of a chronic eczema patient, and after 30 days of treatment, the score of an experimental group is reduced from 7.93 to 4.0 (a control group has no remarkable change). The polypeptide is natural in source and high in safety, and a new strategy is provided for eczema treatment.

The application belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine compound preparation for treating anal eczema as well as a preparation method and application thereof. The traditional Chinese medicine compound preparation is prepared from the following raw medicinal materials in parts by weight: 35-45 parts of Sophora flavescens, 35-45 parts of Cnidium monnieri, 18-22 parts of Semen Astragali Complanati, 18-22 parts of Cortex Dictamni, 18-22 parts of Scutellaria baicalensis, 118-22 parts of Phellodendri, 10-14 parts of Chuanxiong Rhizoma, 16-20 parts of Angelica sinensis, 10-14 parts of Radix Paeoniae Alba, 16-20 parts of Saposhnikovia divaricata, and 10-14 parts of Gleditsia sinensis. The application provides a traditional Chinese medicine compound preparation and a Chinese medicine treatment method for treating acute and chronic anal eczema caused by 'damp-heat invasion'. The traditional Chinese medicine compound preparation can not only significantly relieve the perianal pruritus and exudation of the patients with anal eczema, but also effectively reduce the skin lesion area and improve the skin lesion state, and the clinical curative effect is obvious. In addition, the raw materials of the traditional Chinese medicine compound preparation are widely sourced and low in price, the pure traditional Chinese medicine raw materials are used for processing, and the preparation process is simple.

The invention provides a Baiqing essential oil composition for treating blood deficiency and wind dryness syndrome of chronic eczema, and belongs to the field of biological medicine. The white tea essential oil composition comprises sweet wormwood essential oil and white tea essential oil, the mass ratio of the artemisia apiacea essential oil to the white tea essential oil is (1-5): 1. The Baiqing essential oil emulsifiable paste is guided by the theory of traditional Chinese medicine and follows the theory and principle of prescription compatibility, the artemisia apiacea is used as the monarch for clearing heat and expelling evil, the white tea is used as the minister for eliminating dampness and treating sores, and the effects of resisting inflammation and relieving itching are jointly achieved. Vaseline is used as a matrix, oily substances are used for nourishing and moistening the skin and enhancing the efficacy, and the traditional Chinese medicine composition has an excellent effect on treating the blood deficiency and wind dryness syndrome of chronic eczema, especially the blood deficiency and wind dryness syndrome of mild and moderate chronic eczema. Compared with vaseline or an artemisia apiacea / white tea essential oil mixture which is independently used, the white tea and green tea essential oil emulsifiable paste has a better treatment effect and plays a synergistic interaction role. The invention provides a new clinical basis for subsequent traditional Chinese medicine treatment of chronic eczema (blood deficiency and wind dryness syndrome).

The invention provides a composition for treating chronic wounds and a preparation method and application thereof, and belongs to the technical field of chronic wound treatment. The composition for treating the chronic wound surface, provided by the invention, is prepared from the following raw materials in parts by weight: 8 to 12 parts of brown sugar, 8 to 12 parts of rhizoma coptidis, 8 to 12 parts of radix ampelopsis, 12 to 18 parts of cortex ilicis rotundae, 10 to 12 parts of radix sanguisorbae and 0.5 to 1.5 parts of resina draconis. The composition for treating chronic wounds provided by the invention is rigorous in compatibility and distinct in monarch, minister, assistant and guide. Brown sugar and coptis chinensis are used as monarch drugs; the ministerial drugs ampelopsis japonica and ovateleaf holly bark help the monarch drug to clear damp and promote tissue regeneration; sanguisorba officinalis and dragon's blood are used as adjuvant drugs for removing blood stasis and activating blood to promote wound healing. All the components are combined to jointly achieve the effects of clearing heat, eliminating dampness, promoting blood circulation and promoting tissue regeneration, and are exactly combined with the pathogenesis of damp-heat stasis resistance and difficulty in healing wounds, so that the traditional Chinese medicine composition is suitable for treating chronic refractory wounds, pressure sores, non-healing wounds after operations, chronic eczema, bedsores and other durable and unhealed symptoms, and also has the effect of inhibiting pathogenic bacteria.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine compound preparation for treating anal eczema and a preparation method and application thereof.The traditional Chinese medicine compound preparation is prepared from, by weight, 35-45 parts of radix sophorae flavescentis, 35-45 parts of fructus cnidii, 18-22 parts of fructus kochiae, 18-22 parts of cortex dictamni, 18-22 parts of radix scutellariae, 118-22 parts of cortex phellodendri, 10-14 parts of ligusticum wallichii and 16-20 parts of angelica sinensis. , 10-14 parts of garden burnet, 16-20 parts of divaricate saposhnikovia root, and 10-14 parts of spina gleditsiae. The invention provides a traditional Chinese medicine compound preparation and a traditional Chinese medicine treatment method for acute and chronic anal eczema caused by damp-heat immersion, and the traditional Chinese medicine compound preparation not only can obviously relieve perianal itching, seepage and other symptoms of patients with anal eczema, but also can effectively reduce the skin lesion area and improve the skin lesion state, and is obvious in clinical curative effect. In addition, the traditional Chinese medicine compound preparation is wide in raw material source and low in price, is processed from pure traditional Chinese medicine raw materials, and is simple in preparation process.

The application discloses a traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: radix astragali 40-80, rhizoma et herba 10-50, raw ginger 5-40, radix glycyrrhizae 5-40, ephedra 5-40, ramulus cinnamomi 10-50, radix scrophulariae 10-40, radix sophorae 10-40, radix alpiniae oxyphyllae 10-50, rhizoma pinelliae 5-40, pericarpium citri reticulatae 5-40, rhizoma chuanxiong 5-40, radix ponicis cum cortex 10-40, fructus corni 5-40, radix gentianae 5-40, radix clematidis 10-40, radix rehmanniae 20-60, radix scrophulariae 10-50, radix paeoniae alba 10-50, cortex mali 5-40, radix et rhizoma 5-40, prepared scrophulariae 5-40, scolopendra 5-40 and rhabdophis 10-50. The traditional Chinese medicine composition can treat chronic eczema by oral administration, and has the advantages of remarkable effect and safety and reliability.

The invention relates to the technical field of medicines, in particular to a wood vinegar skin care composition for cold-dampness constitution and application of the wood vinegar skin care composition. The wood vinegar skin care composition is prepared from the following components: wood vinegar, perilla leaves, rhizoma zingiberis, rhizoma atractylodis macrocephalae, pericarpium citri reticulatae, semen euryales, radix angelicae sinensis, pericarpium zanthoxyli and fructus forsythiae. When the wood vinegar skin care composition provided by the invention is used for treating cold-dampness constitution chronic eczema patients, the cure rate reaches 95% or above, and the chronic eczema does not relapse within 4 months.

This invention relates to the field of pharmaceutical technology, specifically disclosing a polypeptide extracted from the traditional Chinese medicine Artemisia argyi, the amino acid sequence of which is shown in SEQ ID No. 1. This polypeptide can be prepared from Artemisia argyi through steps such as ultrasonic disruption, enzymatic hydrolysis, and purification. Experiments show that the Artemisia argyi polypeptide at a concentration of 2 μg / mL inhibits Staphylococcus aureus by 92±4.72%. This invention also provides a medicated bath component containing the Artemisia argyi polypeptide, which can significantly alleviate itching, lesion area, and morphology in patients with chronic eczema. After 30 days of treatment, the experimental group's score decreased from 7.8 to 3.1 (the control group showed no significant change). The polypeptide of this invention is naturally derived and highly safe, providing a new strategy for the treatment of eczema.

The present invention relates to the technical field of new drug indications, and specifically discloses an external use preparation of bletilla striata polysaccharide for preventing and treating eczema and pruritus, its preparation method and application. The present invention proves through scientific experiments that the external use preparation of bletilla striata polysaccharide can promote the rapid regression of acute and chronic eczema symptoms induced by dinitrofluorobenzene (DNFB) in rats within a short period of time, and its prevention and treatment effect is significantly better than the commonly used control drugs in clinical practice of traditional Chinese and Western medicine (compound phellodendron liquid, Binghuang Fule ointment, compound dexamethasone acetate cream), and can also rapidly inhibit the pruritus signs in mice induced by the combined use of histamine and 4-aminopyridine, and its prevention and treatment effect is also close to the commonly used control drugs in clinical practice of traditional Chinese and Western medicine (Qingpeng ointment, compound dexamethasone acetate cream).

The invention relates to a composition and application thereof in preparation of a product with an eczema treatment effect. The composition mainly comprises the following components: aesculus chinensis, radix rehmanniae recen, liquorice, semen coicis, golden cypress, coptis chinensis, rhizoma atractylodis, schizonepeta, poria cocos and radix angelicae. According to the invention, the main medicinal materials are firstly crushed, then boiled with water to extract beneficial components, and finally effective components are concentrated for nano-liposome embedding treatment, so that the loss of the beneficial components of the medicinal materials is effectively prevented, and meanwhile, the absorption of the body is promoted. The traditional Chinese medicine composition and the traditional Chinese medicine extract provided by the invention are natural in raw materials, wide in source and simple in preparation method, have a remarkable treatment effect on acute eczema, subacute eczema and chronic eczema, can remarkably improve skin symptoms such as itching, papule, seepage, erythema, skin lesion erosion and the like of patients, are exact in curative effect, are not easy to relapse after being cured, and are free of toxic and side effects. Good clinical application values are realized.

The present invention provides a traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof. The traditional Chinese medicine composition mainly has the functions of strengthening the spleen and regulating the stomach, clearing heat and resolving dampness, and also cooling blood and promoting blood circulation, and finally dispelling the three evils of wind, dampness and heat to restore health. It has a significant effect on relieving the condition of patients with chronic eczema and preventing recurrence, and provides a new choice for the medication and drug usage method in the clinical treatment of chronic eczema. The traditional Chinese medicine composition is composed of 20-25 parts by weight of stir-fried hawthorn, 20-25 parts by weight of medicated leaven, 15-20 parts by weight of purslane, 10-15 parts by weight of forsythia, 10-15 parts by weight of alisma orientale, 15-20 parts by weight of poria cocos, 15-20 parts by weight of coix seed, 10-15 parts by weight of stir-fried semen raphani, 10-15 parts by weight of atractylodes macrocephala, 15-20 parts by weight of raw rehmannia root, 15-20 parts by weight of moutan bark, 10-15 parts by weight of cortex cercidis, 10-15 parts by weight of cortex lycii radicis, 10-15 parts by weight of cortex mori, and 6-10 parts by weight of raw liquorice root. The traditional Chinese medicine composition is prepared into an external preparation.

The application discloses a medicine for treating chronic eczema, and the medicine is prepared from Tripterygium wilfordii, Coptis chinensis, Rheum officinale, Saposhnikovia divaricata, Schizonepeta, Angelica sinensis, Radix Paeoniae Alba, Sophora flavescens, borneol, licorice and menthol. The medicine has the functions of clearing heat and resolving toxins, dispelling wind and dampness, and harmonizing blood and stopping itching, and is suitable for people with chronic eczema of the type of wind (damp) heat accumulating on the skin.