1771 results about "Staphyloccocus aureus" patented technology

The invention relates to a mouse anti-PBP2a hybridoma cell strain, a monoclonal antibody and application of the mouse anti-PBP2a hybridoma cell strain, staphylococcus aureus PBP2a protein is extracted as an antigen, after the high-purity antigen is obtained, a good immunoreaction is aroused in a mouse body, then a hybridoma technology is adopted, two cell strains with high affinity and specificity are screened, and the corresponding antibody is prepared; the two antibodies are used as a gold-labeled antibody and a coating antibody in a colloidal gold immunoassay kit, and the kit can be used for detecting PBP2a protein in methicillin-resistant staphylococcus aureus and can be used for developing related in-vitro diagnostic reagents.

The invention discloses a lactobacillus mucus fermentation strain and application thereof, and provides a lactobacillus mucus fermentation strain A10 with high yield of exopolysaccharides, and the preservation number of the lactobacillus mucus fermentation strain A10 is CCTCC (China Center for Type Culture Collection) NO: M20242082. The fermented lactobacillus mucus A10 has relatively strong bile salt and gastrointestinal tract digestion tolerance and has an obvious antibacterial effect on escherichia coli and staphylococcus aureus, and the exopolysaccharide synthesized by the fermented lactobacillus mucus A10 is Wzy type exopolysaccharide, is heteropolysaccharide composed of rhamnose, galactose, glucose, mannose and glucuronic acid, and can be used for preparing the exopolysaccharide. The product has good thermal stability and antioxidant activity, and can significantly scavenge free radicals. The lactobacillus mucus A10 extracellular polysaccharide provided by the invention can exert antioxidant activity by activating a Keap1-Nrf2 / ARE signal channel, and is expected to be developed into a natural antioxidant which interacts with Keap1-Nrf2 in a targeting manner.

The invention discloses a plant lactobacillus with a bacteriostatic effect and application of the plant lactobacillus. The lactobacillus plantarum is named as lactobacillus plantarum C07, the preservation number is CCTCC NO: M20242086, the preservation unit is China Center for Type Culture Collection, the preservation time is September 26, 2024, and the preservation address is Wuhan University, Wuhan University, No. 299, eight road, Wuchang District, Wuhan City, Hubei Province. The strain can produce lactic acid and indole-3-lactic acid at high yield, has a very strong antibacterial effect on multiple putrefying and pathogenic microorganisms such as staphylococcus aureus, escherichia coli, listeria monocytogenes, pseudomonas aeruginosa, salmonella and mould, and is a broad-spectrum antibacterial microorganism.

The invention belongs to the technical field of metal organic frameworks, and particularly relates to a high-performance photocatalytic metal organic framework antibacterial material as well as a preparation method and application thereof. The preparation method comprises the following steps of: growing a metal organic framework UiO 66 which takes a cerium element as a metal node on a single-layer graphene oxide UiO66 (at) GO in situ, loading arginine small molecules in the MOF framework to obtain a high-performance photocatalytic MOF antibacterial material UiO66 (at) GO (at) arg, forming a nano hydrogel with a stable three-dimensional structure with chitosan, and performing antibacterial treatment by using the nano hydrogel as a wound dressing. The Ce-based MOF composite QCS / GO-UiO 66-coated arg / PNIPAm hydrogel prepared by the preparation method disclosed by the invention has excellent properties such as elasticity, adhesive power, water absorption and biocompatibility; and under illumination, the photocatalyst has an excellent photocatalytic sterilization effect, and has a good killing effect on escherichia coli and staphylococcus aureus.

The invention relates to the field of microorganisms, and discloses lactobacillus plantarum with an antibacterial effect and application of the lactobacillus plantarum, and the preservation number of the lactobacillus plantarum is CGMCC (China General Microbiological Culture Collection Center) No.33151. The strain provided by the invention has relatively strong cholate resistance, gastric acid resistance, acid production and H2O2 production capabilities, and has a relatively strong bacteriostatic effect on common pathogenic bacteria such as staphylococcus aureus, candida albicans, escherichia coli, salmonella and helicobacter pylori; the compound can inhibit the activity of urease, interfere helicobacter pylori colonization and the like to inhibit helicobacter pylori infection or reduce the symptoms of helicobacter pylori infection and reduce the disease degree of mice with colitis, can be used for preparing microbial preparations, and has the potential of preparing drugs for preventing and / or treating diseases caused by helicobacter pylori infection.

The invention relates to a composite hydrogel dressing for promoting wound healing as well as preparation and application thereof, and belongs to the technical field of biological medicines. The hydrogel disclosed by the invention is prepared by mixing gelatin, oxidized dextran and metal ion modified metal-organic framework compounds (MOF-Ag and MOF-Cu). In the mixed solution, amino groups in the gelatin and aldehyde groups of the oxidized dextran are subjected to a Schiff base cross-linking reaction, and the composite hydrogel is formed after standing. The loaded MOF-Ag has antibacterial and anti-biofilm effects on staphylococcus aureus and escherichia coli, and the loaded MOF-Cu has similar superoxide dismutase activity and similar glutathione peroxidase activity, so that excessive active oxygen can be removed, and inflammatory response can be relieved. The obtained hydrogel has good biocompatibility, proper mechanical properties and biological adhesion, stable rheological properties, excellent antibacterial and anti-inflammatory functions and a certain hemostatic function.

The invention belongs to the technical field of antibacterial drugs, and discloses a pleuromutilin derivative and a preparation method and application thereof.The pleuromutilin derivative is a compound with the structure shown in the formula I and pharmaceutically acceptable salt of the compound, and in the formula, R1, R2 and R3 are H, OMe, NO2, Me, F, Cl or Br. According to the present invention, the structure is novel, the antibacterial activity is excellent, and the in vitro antibacterial experiment result shows that the antibacterial activity of more than 90% of the compound on the Gram-positive bacteria staphylococcus aureus drug-resistant strains ATCC 33591 and ATCC 43300 and the staphylococcus aureus sensitive strain ATCC 2913 is superior to the antibacterial activity of tiamulin, such that the tiamulin is expected to be used in the treatment of the bacterial infection caused by the staphylococcus aureus, and the application prospect is broad. And a new choice is provided for anti-infection drugs.

The invention belongs to the technical field of antibacterial drugs, and discloses a coumarin thioether pleuromutilin derivative and application thereof.The coumarin thioether pleuromutilin derivative is a compound with the structure shown in the formula I and pharmaceutically acceptable salt of the compound, and in the formula, R1 and R2 are H, OMe, NO2, NH2, Me, F, Cl or Br. The antibacterial agent is novel in structure and has excellent antibacterial activity. In-vitro antibacterial experiment results show that all the compounds have antibacterial effects superior to that of tiamulin, most of the compounds have antibacterial effects equivalent to that of control valnemulin, and the compound has a significant effect on five gram-positive bacteria staphylococcus aureus drug-resistant strains ATCC 33591 and ATCC 43300, staphylococcus aureus sensitive strains ATCC 2913, staphylococcus epidermidis drug-resistant strains ATCC 51625, staphylococcus epidermidis sensitive strains ATCC 12228, staphylococcus aureus drug-resistant strains ATCC 51625, staphylococcus aureus sensitive strains ATCC 12228, staphylococcus aureus drug-resistant strains ATCC 51625 and staphylococcus aureus sensitive strains ATCC 12228. Wherein the bacteriostatic activities of the nine compounds are less than or equal to 0.062 mu g.mL <-1 >. The compound is expected to be applied to treatment of bacterial infection caused by staphylococcus aureus, and a new choice is provided for anti-infection drugs.

The invention relates to the field of microorganisms, and discloses lactobacillus plantarum and application of the lactobacillus plantarum in preparation of a medicine for preventing and / or treating vaginitis, and the preservation number of the lactobacillus plantarum is CGMCC No.33152. The lactobacillus plantarum provided by the invention has a relatively strong bacteriostatic effect on common vaginal pathogenic bacteria such as Atortoria, staphylococcus aureus, Candida albicans, Escherichia coli and Gardneria, and also can reduce the infection degree of the pathogenic bacteria by inhibiting colonization and reproduction of the pathogenic bacteria; in addition, the proinflammatory factor level in sick vaginitis tissues is reduced, and the anti-inflammatory factor level is improved.

The invention discloses an epoxy group modified zwitterionic polymer / heparin composite coating and a preparation method thereof. The preparation method comprises the following steps: firstly, constructing an amino-containing adhesion layer on the surface of a substrate by adopting a dip-coating method; then, the substrate is soaked in a mixed solution of the zwitterionic polymer and the heparin, and grafting of the zwitterionic polymer and the heparin on the surface of the medical material is completed through incubation. The coating provided by the invention has excellent hydrophilicity, can form a hydration layer, provides a physical barrier, and remarkably prevents adhesion and colonization of microorganisms. The inhibition rate of the coating on escherichia coli and staphylococcus aureus exceeds 99%, protein adhesion is remarkably reduced in an anti-protein adhesion experiment, and the coating is simple in strategy design, has a potential application prospect in the aspect of preventing blood contact catheter related infection and thrombosis, and has a wide application prospect. The complication occurrence rate and the medical care cost can be reduced.

The invention relates to lactobacillus gasseri FMTA1125B with the effect of preventing, relieving or treating vaginitis and application of the lactobacillus gasseri FMTA1125B. The lactobacillus gasseri FMTA1125B is classified and named as lactobacillus gasseri, and the preservation number of the lactobacillus gasseri FMTA1125B is CGMCC No.34292. The lactobacillus gasseri FMTA1125B has the effects of preventing, relieving or treating vaginitis and the application of the lactobacillus gasseri FMTA1125B. The bacterium can produce beneficial components such as lactic acid, gamma-aminobutyric acid and hydrogen peroxide through metabolism so as to regulate the genital tract environment and improve the health degree; and the traditional Chinese medicine composition has relatively good bacteriostasis and sterilization effects on common vaginal pathogenic bacteria such as escherichia coli, staphylococcus aureus, gardnerella vaginalis, candida albicans, neisseria gonorrhoeae and the like. Therefore, the lactobacillus gasseri FMTA1125B strain can be used for preparing a preparation with the effect of improving related genital tract diseases such as vaginitis.

The invention discloses an antibacterial peptide SAMP4 or a derivative thereof, a pharmaceutical composition and application, and belongs to the technical field of biology, the amino acid sequence of the antibacterial peptide SAMP4 is as shown in SEQ ID NO: 1, and the antibacterial peptide SAMP4 has a broad-spectrum antibacterial effect and can be used for preparing antibacterial peptide SAMP4. The compound has a strong bacteriostatic effect on various gram-positive bacteria such as staphylococcus aureus, enterococcus and streptococcus and various gram-negative bacteria such as escherichia coli, acinetobacter baumannii and pseudomonas aeruginosa, and is strong in antibacterial activity, wide in antibacterial spectrum and low in toxicity. The invention also provides a derivative and a salt of the antibacterial peptide SAMP4 and application of the antibacterial peptide SAMP4 and the derivative and the salt of the antibacterial peptide SAMP4 to research, development and preparation of various antibacterial products or / and antibacterial drugs and treatment of bacterial infectious diseases, and the antibacterial peptide SAMP4 and the derivative and the salt of the antibacterial peptide SAMP4 are remarkable in advantages and wide in application prospect.

The invention discloses lactococcus gasseri C6a2 and application thereof. The preservation number of the lactococcus gasseri C6a2 is CGMCC (China General Microbiological Culture Collection Center) NO: 31024; the 16S rRNA (ribosomal Ribonucleic Acid) gene sequence of the lactococcus gasseri C6a2 is as shown in SEQ ID NO: 1. The bacterial strain is a macrobrachium rosenbergii intestinal absolute dominant bacterium, has a typical probiotic function, is high in growth speed and activity, can quickly enter a logarithmic phase, has relatively high acid production and acid resistance, can secrete lipase, has relatively high bacteriostatic activity on staphylococcus aureus, aeromonas hydrophila and aeromonas veronii, and can be used for preparing the macrobrachium rosenbergii. The bacterium can be used for preparing a special probiotic preparation for macrobrachium rosenbergii, so that the sustainable development of the macrobrachium rosenbergii industry in China is promoted.

The invention relates to the technical field of antibacterial peptide application, in particular to an antibacterial peptide for inhibiting drug-resistant staphylococcus aureus and application of the antibacterial peptide. The antibacterial peptide is obtained by performing N-terminal acetylation modification and C-terminal amidation modification on polypeptide as shown in SEQ ID NO.1. The invention further discloses a preparation method of the antibacterial peptide. The antibacterial peptide provided by the invention is a novel cationic antibacterial peptide, the minimum inhibitory concentrations of the antibacterial peptide to pathogenic bacteria staphylococcus aureus ATCC12600 and staphylococcus aureus ATCC33591 are respectively 4 [mu] g / mL and 32 [mu] g / mL, the biological safety is extremely high, and due to the characteristics, the antibacterial peptide shows extremely high medical drug antibacterial value, and can be used for preparing the antibacterial peptide. Alternative medicinal resources are provided for clinically resisting the two human pathogenic bacteria in the future.

The invention provides lactobacillus crispatus, which is preserved in the general microbiological center of the China Committee for Culture Collection of Microorganisms on February 7, 2023, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) No. 26503. The bacillus subtilis can play a relatively strong role in inhibiting pathogenic bacteria such as gardnerella vaginalis, escherichia coli and staphylococcus aureus at the same time, and also has a certain role in inhibiting candida albicans, two-way proteurella and Atortoria vaginalis. Therefore, the lactobacillus crispatus has the potential of maintaining the environment in the vagina to be faintly acid and improving the mucosal immunity and infection resistance of a host, and can be used for preventing and treating vaginal infection and inflammation, and maintaining, improving or recovering the steady state of the environment in the vagina.

The invention discloses an antibacterial peptide and application thereof, and belongs to the technical field of biology. The antibacterial peptide with an inhibition effect on various clinically common pathogenic microorganisms is obtained, and the antibacterial peptide comprises gram-negative bacteria such as escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, acinetobacter baumannii, vibrio parahaemolyticus, salmonella gallinarum, salmonella typhimurium and enterobacter sakazakii, and gram-positive bacteria. The antibacterial peptide provided by the invention can be used as an antibacterial peptide, such as staphylococcus aureus, listeria monocytogenes and bacillus cereus, and the antibacterial peptide provided by the invention is novel in structure and easy to prepare.

The invention discloses an antibacterial peptide and application thereof. The amino acid sequence of the antibacterial peptide disclosed by the invention is KKKEHRLLHRVLFHRL. The minimum inhibitory concentration of the antibacterial peptide to staphylococcus aureus is 4.5 mu g / mL, and the minimum bactericidal concentration of the antibacterial peptide to staphylococcus aureus is 72.7 mu g / mL. The antibacterial peptide disclosed by the invention has remarkable antibacterial activity on staphylococcus aureus and is expected to be widely applied as a novel bacteriostatic agent for preventing and treating staphylococcus aureus.

The invention belongs to the technical field of medicines, and particularly relates to application of sesquiterpenoids and / or pharmaceutically acceptable salts thereof in preparation of medicines for treating or preventing infectious diseases caused by staphylococcus aureus. The invention relates to the field of medicines, in particular to application in preparation of medicines for treating or preventing infectious diseases caused by drug-sensitive staphylococcus aureus or drug-resistant staphylococcus aureus. The structure of the sesquiterpenoids is shown as a formula I in the specification. The sesquiterpenoids applied in the invention are derived from rattan chrysanthemum, the source is wide, and the production cost is low. The sesquiterpenoids shown in the formula I have a very good activity inhibition effect on staphylococcus aureus for the first time, and the sesquiterpenoids have a very good activity inhibition effect on staphylococcus aureus with drug sensitivity, drug medium or drug resistance.

The invention belongs to the technical field of antibacterial peptides, and particularly relates to an antibacterial peptide and application thereof. The amino acid sequence of the antibacterial peptide is shown as SEQ ID NO: 1, the number of amino acids is small, the synthesis cost is low, the antibacterial peptide has high antibacterial activity on gram-negative bacteria and gram-positive bacteria, the minimum inhibitory concentration of the antibacterial peptide on acinetobacter baumannii, escherichia coli, pseudomonas aeruginosa and staphylococcus aureus is 4.68-37.5 mu g / mL, and the antibacterial peptide has the advantages of broad-spectrum antibacterial property, good stability and good application prospect. No obvious cytotoxicity and hemolysis effect exist; moreover, end-to-end amido bond cyclization is carried out, so that the antibacterial activity is further enhanced, the antibacterial effect on acinetobacter baumannii, escherichia coli, pseudomonas aeruginosa and staphylococcus aureus is enhanced by 2-4 times, and the minimum inhibitory concentration is reduced to 2.34-9.38 mu g / mL; after the end-to-end amido bonds are cyclized, the plasma stability and safety of the antibacterial peptide are further improved, and the cytotoxicity and hemolysis are reduced.

The invention belongs to the technical field of microorganisms, and particularly relates to a lactobacillus polyactis composition for improving skin as well as a derivative and application of the lactobacillus polyactis composition. The composition comprises a bacterial strain, a pure culture or an inactivated bacterium body of bifidobacterium bifidum Bbifid-1 (CCTCC NO: M2023349), bifidobacterium adolescentis Badol-1 (CCTCC NO: M 20242593), phytobacterium plantarum Lplan-4 (CCTCC NO: M 20242594) and lactobacillus acidophilus (BA05). The invention further relates to a preparation method of the composition. The lactobacillus plantarum derivative composition prepared through treatment modes of splitting decomposition, extraction, fermentation and the like can be used as an active ingredient of a medicine or a cosmetic, has remarkable effects of resisting oxidation and bacteria, especially resisting inflammation and inhibiting skin lipid accumulation aiming at propionibacterium acnes and staphylococcus aureus, is beneficial to fading skin red and swollen, avoids hair follicle blockage, and has a good application prospect. The obvious effect on the acne is realized.

The invention relates to the technical field of acrylic resin, and discloses a salt-spray-resistant epoxy modified waterborne acrylic resin emulsion as well as a preparation method and application thereof, the waterborne acrylic resin emulsion comprises 100 parts by weight of vinyl monomer, 0.4-0.5 part by weight of initiator, 2-2.8 parts by weight of emulsifier and 10-35 parts by weight of cationic Schiff base modified epoxy resin; after the epoxy resin is subjected to cationic modification, an antibacterial cationic quaternary ammonium salt group is introduced into a molecular chain, so that a very good bactericidal effect can be achieved, and the epoxy resin shows a good antibacterial rate on escherichia coli and staphylococcus aureus. The acrylic resin is endowed with excellent antibacterial performance. Meanwhile, the adhesive force, the water resistance, the salt spray resistance and the like of a paint film are improved, and the paint film shows better corrosion resistance.

The invention discloses a hydrogel dressing with a double-slow-release effect as well as a preparation method and application of the hydrogel dressing. The preparation method of the hydrogel dressing comprises the following steps: firstly, preparing methyl acrylate modified hyaluronic acid capable of being photo-crosslinked, then preparing carboxymethyl chitosan nanoparticles loaded with chlorogenic acid, and finally, mixing the methyl acrylate modified hyaluronic acid and the carboxymethyl chitosan nanoparticles loaded with chlorogenic acid to obtain the hydrogel dressing. The hydrogel dressing embedded with the nanoparticles is obtained in a photo-crosslinking mode. The hydrogel dressing provided by the invention not only has good biocompatibility and mechanical properties, but also plays an anti-oxidation role by removing free radicals in a body, and can effectively kill bacteria such as escherichia coli and staphylococcus aureus to play an antibacterial role. The hydrogel dressing can also reduce excessive inflammatory response in the wound healing process by influencing macrophage polarization, promote chronic wound healing and relieve pain of patients.

The invention discloses lactobacillus plantarum and application thereof, and aims at solving the technical problems of how to inhibit the growth of malassezia furfur, splitting the malassezia furfur, and inhibiting the growth of pseudomonas aeruginosa and staphylococcus aureus and the formation of a biological membrane. In particular discloses lactobacillus plantarum, the lactobacillus plantarum is lactobacillus plantarum DZ041, and the preservation number of the lactobacillus plantarum is CGMCC (China General Microbiological Culture Collection Center) No.20835 in the General Microbiological Culture Collection Center of the China Committee for Culture Collection of Microorganisms). Bacterial suspension or cell-free fermentation liquor prepared from the malassezia furfur can inhibit the growth of malassezia furfur and even can crack malassezia furfur, and the malassezia furfur can be used for industrial production.

The invention belongs to the technical field of microbiological detection, and particularly relates to a staphylococcus aureus test piece which structurally comprises a transparent covering film, a circular culture area and a bottom plate printed with square grids from top to bottom in sequence, the circular culture area comprises nutrient substances beneficial to growth of staphylococcus aureus, a composite inhibitor, a composite chromogenic enzyme substrate and cold water gel. The staphylococcus aureus test strip disclosed by the invention can be used for rapidly detecting staphylococcus aureus in food and processing environment thereof, human and animal medical sampling samples and other samples, has the characteristics of strong specificity, high sensitivity, short detection period and easiness in observation, and has extremely high development value and wide application prospect.

The invention discloses an antibacterial peptide sequence for inhibiting gram-negative bacteria and application of the antibacterial peptide sequence. A plurality of antibacterial peptides are designed for gram-negative bacteria, and antibacterial test results show that the amino acid sequence shown in SEQ ID No.4 has an exact inhibition effect on two gram-negative bacteria and also has a certain inhibition effect on staphylococcus aureus; in addition, the amino acid sequence as shown in SEQ ID No.2 has an exact inhibition effect on gram-positive bacterium micrococcus luteus and fungus candida albicans, and the inhibition rates are 99.32% and 93.42% respectively. The invention further provides application of the antibacterial peptide in preparation of drugs for resisting bacterial or fungal infection.

The invention discloses an antibacterial finishing agent containing quaternary ammonium salt chitosan and tannic acid as well as a preparation method and application of the antibacterial finishing agent. The antibacterial finishing agent is mainly a mixed solution containing quaternary ammonium salt chitosan, tannic acid and glacial acetic acid. The preparation method comprises the following steps: dispersing chitosan in deionized water, then adding 2, 3-epoxypropyltrimethylammonium chloride, heating and stirring, reacting, and purifying and drying to obtain quaternary ammonium salt chitosan; and dissolving quaternary ammonium salt chitosan in an acetic acid solution, and adding tannic acid to obtain the antibacterial finishing agent. In the application, the fabric is soaked in the antibacterial finishing agent, then soaked in deionized water for washing and finally dried, the finished and modified fabric is high in antibacterial property, the antibacterial rate on escherichia coli is 99.2%, and the antibacterial rate on staphylococcus aureus is close to 100%.

The invention belongs to the technical field of antibiosis and wound healing promotion, and relates to double-response (near-infrared light and hydrogen peroxide double-response photo-thermal / carbon monoxide therapy) antibacterial hydrogel as well as preparation and application thereof. The invention relates to a double-response antibacterial hydrogel. The antibacterial hydrogel is prepared from the following components: drug-loaded nano particles and a hydrogel matrix. The drug-loaded nano particles are prepared by loading dimanganese decacarbonyl (MnCO) into cavities of hollow mesoporous copper sulphide nano particles (HMCuS NPs) and coating the surfaces of the particles with a polydopamine layer (PDA). According to the invention, CO / PTT synergistic treatment of bacterial infected wounds is realized, and the antibacterial effect is significantly improved. An in-vitro antibacterial experiment result shows that the antibacterial hydrogel shows extremely strong inhibition capability on escherichia coli and staphylococcus aureus, and the problem of drug resistance caused by a bacterial biofilm is effectively solved.

The invention provides a thiazolidinone compound and application thereof in preparation of drugs for resisting staphylococcus aureus infection. The molecular structural formula of the thiazolidinone compound is shown as a formula (1), a formula (2), a formula (3) or a formula (4). The technical scheme of the invention discloses several thiazolidinone compounds, which not only have an excellent bactericidal effect on staphylococcus aureus and can significantly inhibit the formation of a biofilm of staphylococcus aureus, but also have low cytotoxicity and hemolytic activity. According to the technical scheme, a certain foundation is laid for research and development of novel staphylococcus aureus biofilm infection resisting drugs, and the potential of thiazolidone derivatives for developing novel antibacterial agents for staphylococcus aureus related infection can be deeply known possibly.

The invention relates to application of ten antibacterial peptides in the antimicrobial field. The ten antibacterial peptides have strong antibacterial activity on multi-drug-resistant bacteria, including but not limited to gram-negative bacteria such as escherichia coli, pseudomonas aeruginosa, acinetobacter baumannii, klebsiella pneumoniae and the like, and gram-positive bacteria such as staphylococcus aureus, enterococcus faecalis and the like. Activity research proves that any one of the ten antibacterial peptides has a remarkable effect of inhibiting, killing or preventing microbial infection. Due to the strong antibacterial property of any antibacterial peptide, the antibacterial peptide has wide application potential in the aspects of preparing antibacterial drugs, preservatives, antibacterial coatings, antibacterial fibers, antibacterial packaging materials and the like. Due to the unique property of the antibacterial peptide in the aspect of antibacterial performance, a new direction is provided for the development of efficient and reliable antibacterial agents and antibacterial technologies and products in multiple fields.

The invention relates to the technical field of antibacterial peptides, and discloses a novel Rhodospirillales antibacterial peptide and application thereof, and the amino acid sequence of the antibacterial peptide is as shown in SEQ ID NO: 1. The antibacterial peptide obtained by the invention has a relatively good antibacterial effect on staphylococcus aureus.