The invention relates to the technical field of medical materials and particularly relates to rapid hemostatic powder for an injury and a preparation method of the rapid hemostatic powder. The rapid hemostatic powder for the injury comprises the following raw materials in parts by weight: 40-56 parts of chitosan quaternary ammonium salt, 28-36 parts of puffball extracts, 8-12 parts of sodium alginate, 1-5 parts of ramie root extracts, 1-5 parts of cirsium setosum extracts, 1-5 parts of madder extracts and 0.5-1.5 parts of carbonized hair extracts. The rapid hemostatic powder for the injury can take a hemostasis effect through various approaches and remarkably shorten the blood coagulation time, also has the effects of inhibiting and resisting bacteria, relieving pain and promoting wound healing and can be widely applied to rapid hemostasis, emergency treatment and treatment of skin scratch, injury and haemorrhoids and relief of scar formation.