This invention belongs to the fields of biomedical materials, flexible electronic devices, and trauma
emergency treatment technology, specifically relating to a
wireless closed-loop thermal
hemostasis system, its preparation method, and its application. This invention utilizes
dopamine-modified
chitosan to prepare a porous
chitosan gel, and introduces a conductive phase into the gel to prepare a composite conductive cryogel. This composite conductive cryogel is connected to a flexible circuit, a
temperature sensing array, a flexible heating unit, and a
wireless PCB control module to prepare a
wireless closed-loop thermal
hemostasis system. When used in traumatic massive hemorrhage, the cryogel exhibits a volume-dependent resistance change after absorbing blood. The
system utilizes this resistance change to achieve real-time monitoring of the bleeding,
hemostasis, and rebleeding processes. The flexible heating unit is controlled via temperature array feedback to rapidly raise the local temperature of the wound within a safe range to the procoagulant zone, thereby achieving automatically triggered and terminated thermal-assisted hemostasis.