The invention relates to clay-enhanced 
cuttlefish bone meal hemostatic gauze and a manufacturing method thereof. The 
hemostatic gauze comprises a substrate material, 
cuttlefish bone meal which is combined on the substrate material and is used as 
hemostat and clay which is combined on the substrate material and is used for enhancing the hemostatic effect, or also comprises other beneficial components which have the promoting effect on 
hemostasis and a connection agent for combining each component on the substrate material. The manufacturing method comprises the following steps of: preparing a suspension 
sizing agent by using water, the 
cuttlefish bone meal and the clay, and heating the suspension 
sizing agent at the temperature of 15 DEG C until the suspension 
sizing agent is boiling; immersing the substrate material into the sizing agent, or 
coating the sizing agent on the substrate material; taking the substrate material impregnated or coated with the sizing agent out, and performing flat pressing or rolling, or after taking the substrate material impregnated or coated with the sizing agent out, covering one side or both sides of the substrate material 
coating with the sizing agent by using medical cotton 
yarn or non-woven fabrics, and performing the flat pressing or the rolling again; and performing 
drying and sterilization to obtain the clay-enhanced cuttlefish bone 
meal hemostatic gauze. The gauze is used for treating surgical haemorrhage; and compared with the treatment of the ordinary gauze, the clay-enhanced cuttlefish bone 
meal hemostatic gauze has the advantages that: the hemostatic time of the hemostatic gauze is shortened by 35.9 to 66.5 percent; and the 
blood loss amount of the hemostatic gauze is reduced by 49.9 to 88.4 percent.