224 results about "Hemodialysis care" patented technology

The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine. The controller is configured to receive the blood pressure value, analyze it, and in response adjust the dialysis process.

Disclosed are vascular access devices, implantable dialysis grafts, and systems including them useful for improved access to implanted medical devices. Also disclosed are implantable hemodialysis vascular access graft devices that facilitate easy, accurate and reproducible cannulation or needle entry into the implanted device by magnetically-locating a portion of the graft that includes one or more paramagnetic materials operably defining the physical boundaries of the target cannulation site/entry port.

The invention discloses a preparation method of a cyclodextrin modified magnetic nano adsorbent and the application of the cyclodextrin modified magnetic nano adsorbent in a hemodialysis adsorption system, belonging to the field of biomedical material. The method takes FeCl3.6H2O, FeCl2.4H2O and ammonia water as raw materials, trisodium citrate (TSC) as a dispersing agent, polyethylene imine (PEI) as a modification substrate and beta-cyclodextrin (CD) as an adsorption functional group, and comprises the steps of synthesizing magnetic nanoparticles which are modified by the TSC and are small in particle sizes, good in dispersion and strong in magnetism by a reverse chemical coprecipitation method; enabling a PEI modified layer to be adsorbed onto the surface of Fe3O4-TSC by electrostatic interaction; grafting the beta-CD by a Schiff base reaction to obtain the cyclodextrin modified magnetic nano adsorbent-Fe3O4-beta-CD. The adsorbent has magnetism, so that the separation and purification process is more convenient and rapider, and the separation and purification cost is low; the cyclodextrin modified magnetic nano adsorbent has better adsorption capacity for hydrophobic toxin in the hemodialysis adsorption system.

A method and/or a composition relates to cleaning and reprocessing a hemodialysis filtration membrane assembly that employs polyvinylpyrrolidone-containing membranes. The method includes the step of treating the assembly with an aqueous mixture or a gas-liquid mixture having an inorganic base and from 100 to 1,000 ppm of a hypochlorite salt, wherein the mixture has a pH between about 12.0 and about 12.5, an oxidation reduction potential of less than 0.5 volts, a temperature of 40° to 55° C. and wherein the mole % of hypochlorous acid, HOCl, relative to the sum of hypochlorous acid plus hypochlorite anion, —OCl, is less than 0.004%. The composition may be used in such a method.

The invention discloses an environment-friendly bio-based polymer hemodialyzer casing material. The casing material is a blend which comprises the following raw materials in percentage by mass: 90-99% of environment-friendly bio-based polymer, 0.4-8% of plasticizer, 0.2-6% of lubricant, 0.1-2% of antioxidant, 0.2-3% of heat stabilizer and 0.1-4% of inorganic filler. The raw material environment-friendly bio-based polymer has the advantages of wide sources and the like, and is renewable and degradable. The prepared environment-friendly bio-based polymer hemodialyzer casing has higher biocompatibility, and can obviously lower the side effect of hemodialysis; and the waste hemodialyzer casing can be degraded by proper treatment, thereby greatly reducing the environmental pollution.

The invention relates to a bioreactor, which is formed by serially connecting a reciprocating-rotation cell culture tank assembly module (104), a gas-dispersion control assembly module (102) and a liquid flow direction control assembly module (103) through a cell culture solution circulation pipeline. A carrier suspension conglutinated with cells is injected into a cell culture tank of a reciprocating bioreactor, and along with the rotation of a step motor and a double-headed peristaltic pump in the liquid flow direction control assembly module, the output of a preceding state hemodialysis unit or a culture solution in a culture solution container enters the circulation pipeline. When the culture solution reaches a dialysis column (301), a corresponding gas is diffused into the culture solution. Then, the culture solution with the corresponding gas is sent into the cell culture tank. After the exchange of substance with cells in the culture tank, the culture solution containing metabolites of cultured cells is sent back into the preceding state hemodialysis unit or the culture solution container through an output port of the cell culture tank and the culture solution circulation pipeline.

The invention provides a system for characterizing a patient undergoing hemodialysis, featuring: 1) a body-worn biometric sensor, worn on a single location of the patient, and featuring: i) sensing elements for measuring electrocardiogram (ECG), thoracic bio-impedance (TBI), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms; ii) a processor for collectively analyzing the ECG, TBI, PPG, and PCG waveforms to determine a set of physiological parameters; and iii) a first wireless transceiver configured to transmit the set of physiological parameters; 2) a gateway system comprising a second wireless transceiver configured to receive the set of physiological parameters; and 3) a data-analytics system configured to analyze the set of physiological parameters to determine the patient's status.

The invention discloses a preparation method of a hemodialysis concentrated solution. The preparation method comprises the following steps that (1) the hemodialysis concentrated solution is prepared in a solution mixing tank; (2) the solution in the solution mixing tank is subjected to second-level filtration; (3) the solution in the solution mixing tank and ozone generated in an ozone generator are input to a storage tank after being mixed through a gas and liquid mixing pump; (4) the solution in the solution mixing tank is pumped back to the solution mixing tank through a circulation pump; (5) the solutions in the solution mixing tank and the storage tank are mixed in a circulative mode until the ozone concentration of the solution in the storage tank reaches 0.050-0.100 mg/L; (6) the hemodialysis concentrated solution is obtained through filling. The preparation method is simple in operation, quick, efficient, and easy to industrialize. Compared with a conventional method, according to products prepared through the method, initial contaminating bacteria in the concentrated solution are reduced, the storage period is prolonged, product quality is better guaranteed, and using safety of a patient is guaranteed.

The invention discloses a hemodialysis analysis method based on double-machine learning. The method is characterized by comprising the following steps of preprocessing gathered training samples of a hemodialysis center; filling the preprocessed training sample according to a Hot-Deck method, deleting the training samples with variable deletion percentage over alpha, performing variable filling onthe training samples with variable deletion percentage which does not exceed alpha, and obtaining the filled training sample; performing important characteristic screening on the filled training sample through Lasso sparse constraint and Random Forest respectively, and combining two sets of screened training samples for obtaining a final training sample; loading the final training sample into a multivariate linear regression model, performing continuous iteration for obtaining a final prediction model. The method of the invention is combined with a predicating model for a machine learning andhemodialysis first analysis plan in artificial intelligence, thereby reducing the load of a hemodialysis room clinical doctor and improving hemodialysis efficiency of a hemodialysis center.

The invention discloses a preparation method of a polylactic acid hemodialysis membrane with a zwitterionic surface. The method comprises the following steps: soaking the polylactic acid hemodialysis membrane into a dopamine solution so as to generate a poly-dopamine modified polylactic acid hemodialysis membrane in a nascent state; taking out the membrane, then placing the membrane into deionized water for oscillation washing, and drying in vacuum so as to obtain a dry poly-dopamine modified polylactic acid hemodialysis membrane; soaking the membrane into an organic solvent for 0.5 to 2 hours, and then adding triethylamine and 2-bromine butyryl bromine for reaction for 6 to 24 hours so as to obtain a polylactic acid hemodialysis membrane with 2-bromine butyryl bromine fixed on the surface; and soaking the membrane into a mixed solution, adding nitrogen, zwitterion, an initiator and ligand for reaction for 1 to 24 hours, then taking out the membrane, washing with water and ethanol in sequence, and performing vacuum drying. The membrane prepared by the preparation method disclosed by the invention has the advantages that the hydrophilia is obviously improved, the blood penetration resistance is reduced, an ultrafiltrate coefficient is obviously increased, the biocompatibility of the membrane is improved, and the side effects of hemodialysis are reduced.

The invention belongs to the technical field of medical instruments, and particularly relates to hemodialysis auxiliary nursing apparatus. The hemodialysis auxiliary nursing apparatus comprises a bedbody, wherein a supporting plate is arranged on the bed body, an overturning plate is rotationally connected with the supporting plate, an overturning structure for driving the overturning plate to overturn along the supporting plate is arranged on the bed body, the bed body is further provided with massage apparatus corresponding to the supporting plate, the massage apparatus comprises two columns of first massage structures for performing vibration massage on legs, the first massage structures are fixedly connected with the supporting plate, a massage cavity is fixedly connected with the bedbody, a driving structure is connected in the massage cavity in a slide manner, the driving structure drives the first massage structures to vibrate and massage the legs in the sliding process, two sides of the driving structure are each connected with a pair of second massage structures, the two pairs of second massage structures are arranged on two sides of the two columns of first massage structures, and the second massage structures comprise massage rods which move up and down while rotating in the sliding process of the driving structure to massage the legs. The hemodialysis auxiliary nursing apparatus effectively solves the problem that existing hemodialysis auxiliary nursing apparatus is relatively poor in use effects.

The invention relates to the technical field of hemodialysis supports, and discloses an upper limb fixing support frame for hemodialysis nursing. The support frame comprises a bed body; a first air bag is fixedly arranged between telescopic rods; a rotating plate is rotatably installed above the first air bag; pull ropes are fixedly connected to the upper portion of the rotating plate; the outer ends of the pull ropes are fixedly connected with the telescopic rods; a driving rod is movably installed on the left side of the corresponding telescopic rod; a manual rod is rotatably installed at the upper end of the left side of the driving rod; and a second air bag is fixedly installed in a movable frame. According to the upper limb fixing support frame for hemodialysis nursing, the manual rodis pulled by the hand to enable the driving rod to be separated from a limiting groove in the corresponding telescopic rod, then certain pressure is exerted downwards to enable the telescopic rods tomove downwards to squeeze the first air bag, meanwhile the pull ropes pull the rotating plate to be opened, air in the first air bag enters the second air bag, and the movable frame loses supportingforce of the first air bag and moves downwards, so that the effect of freely adjusting the height of the support frame is achieved.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.

The invention relates to a preparation method of anticoagulant property acrylic ester copolymer membrane, and to the technology field of biology medical material preparation. The invention can prepare the acrylic ester copolymer in one-step by free radical polymerization, and then obtain the acrylic ester copolymer membrane by the evaporation of solution. The molecular weight, glass-transition temperature and mechanical strength of the acrylic ester copolymer membrane prepared in the method of the invention are controlled. The invention has anticoagulant property, and can be used in medical apparatus like hemodialysis. The invention provide a simple and high performance method for preparing anticoagulant property copolymer membrane.

The invention discloses a clinical hemodialysis conversion device used in a nephrology department, and relates to the technical field of medical instruments. The device includes a hemodialysis machineand a box body, the upper surface of the box body is provided with an opening, two lateral slide grooves are arranged in the parts, close to the top inner wall of the box body, the box body is slidingly connected with two baffles through the two lateral slide grooves, and a linkage mechanism is fixedly installed at the lower surface of each baffle; and a lifting mechanism is fixedly installed atthe inner wall of the box body. According to the device, through the cooperation among the above structures, the hemodialysis machine is convenient to store and use, and the phenomenon of shaking of the hemodialysis machine in the movement process is avoided; at the same time, the elastic force of compression springs can effectively has the effect of buffering, so that the problems that in a traditional device, a hemodialysis machine is inconvenient to store, and when collision occurs during the movement, internal components of the hemodialysis machine are easily damaged due to vibration are solved.

The invention relates to the technical field of medical instruments, in particular to a bedside fixing device for nursing in a hemodialysis room. The bedside fixing device comprises a bottom plate, avertical plate is fixedly connected to the upper surface of the bottom plate, a vertical limiting sliding groove is formed in the front side face of the vertical plate, a protruding plate is connectedto the top end of the vertical plate, a driving motor is arranged on the upper surface of the protruding plate, an output shaft of the driving motor penetrates through an end of the protruding plateand is connected with a vertical lead screw through a coupler, a bearing pedestal is arranged on the portion, below the vertical limiting sliding groove, of the front side face of the vertical plate,the lower end of the vertical lead screw is connected with the bearing pedestal, and a horizontal long-strip plate is arranged above the bottom plate. A dialysis tube can be rapidly clamped in the hemodialysis process, the clamping effect is excellent, moreover, rapid clamping and taking-down can be achieved, the complex step that an existing hemodialysis pipeline fixing clamp needs to be fixed byscrewing in or out a bolt is avoided, and the bedside fixing device is simple and rapid to operate.

The invention discloses a dialyzer batch production control method, a dialyzer, a dialysis system and a dialyzer management method for batch production. The dialyzer batch production control method comprises the steps that hemodialysis parameters are obtained, and production batch parameters of the dialyzer are set according to the hemodialysis parameters; the dialyzers are produced according to the production batch parameters, after production of the dialyzers of one batch is completed, medical identification data of the dialyzers of the batch are generated, and the medical identification data of the dialyzers of the same batch are the same; and sterilizing and packaging are carried out on the dialyzers, a unique identification number is set for each dialyzer, and the identification numbers are set on shells and/or packages of the dialyzers. The invention further provides the dialyzer and the dialysis system which are produced by the method, and further provides the management method of the dialyzer. The treatment effect of the dialyzer can be improved, and a dialyzer manufacturer can conveniently improve the production process of the dialyzer.

The invention relates to a centralized liquid supply system for hemodialysis with self-cleaning function and a working method thereof, comprising a liquid dispensing device, a disinfection device, a liquid storage device and an infusion pipeline. The outlet end of the liquid device is connected to the inlet end of the ozone generator through the pipeline, the outlet end of the ozone generator is connected to the inlet end of the gas-liquid mixing pump through the pipeline, and the outlet end of the gas-liquid mixing pump is connected to the liquid storage device through the pipeline. The inlet end is connected, so that the concentrated liquid in the liquid dispensing device flows through the pipeline, the ozone generator, and the gas-liquid mixing pump to be mixed with the ozone generated by the ozone generator, and the outlet end of the liquid storage device is connected with the infusion pipeline through the pipeline. The outlet end of the gas-liquid mixing pump is connected with the inlet end of the liquid dispensing device through a return line that can be turned on and off, and the infusion line is connected with the outlet end of the liquid storage device through a return line that can be turned on and off.

The invention discloses a preparation method of an antibacterial glove for hemodialysis care. The preparation method comprises the following steps of (1) preparation of polythiazide 1,2- diamido-5-trifluoromethyl benzimidazolamide, (2) glove forming, and (3) ion exchange. The invention further discloses the antibacterial glove for the hemodialysis care obtained according to the preparation methodof the antibacterial glove for the hemodialysis care. The antibacterial glove for the hemodialysis care has the advantages that the biocompatibility is good, the mechanical performance, abrasion resistance, ageing resistance, anti-static electricity and antibacterial property and infectious prevention are excellent, anticoagulation and antithrombosis are excellent, and the use is safe and reliable.

The invention discloses a kidney disease hemodialysis scheme customization method and system based on an AI technology. The method comprises the steps of arranging to-be-customized user data, and substituting the to-be-customized user data into a dialysis scheme generation model to generate one or more dialysis schemes; substituting to-be-customized user data and one or more dialysis schemes intoa hemodialysis abnormal condition evaluation model to obtain an abnormal condition evaluation result of the one or more dialysis schemes; determining a kidney disease hemodialysis customized scheme according to the abnormal condition evaluation result; wherein the hemodialysis abnormal condition evaluation model is obtained by training through a machine learning CART decision tree algorithm according to historical dialysis data. According to the invention, the machine learning model is established according to the historical dialysis data, the possible adverse reaction of the current body state of the patient in a certain dialysis scheme is predicted in advance, the personalized dialysis scheme is formulated, the dialysis risk is effectively minimized, the safety of the patient is ensured,and the medical care quality is improved.

The invention relates to the technical field of medical instruments, in particular to a dialysis chair special for medical pediatrics. The dialysis chair comprises a cushion, a backrest, a headrest, foot pads, armrests and supporting legs, wherein the backrest and the foot pads are respectively arranged at two ends of the cushion; the headrest is arranged at the upper end of the backrest; the supporting legs are arranged below the cushion; two ends of the armrests are respectively arranged on the cushion and the backrest; an oval notch is formed in the center of the cushion, an electric telescopic rod is controlled to be shortened; a supporting plate is replaced with the medical toilet bowl for children, the electric telescopic rod is controlled to be lifted, the medical toilet bowl for children is lifted into the oval notch formed in the cushion, at the moment, the children can directly urinate or defecate, use is more convenient, and the children can urinate or defecate more conveniently in the dialysis process; and an electric heating layer is arranged, so that the pain of a patient due to temperature discomfort caused by the medical dialysis chair in the hemodialysis process can be relieved.

In a bicarbonate container for one-time use with a hemodialysis apparatus which container consists of a bottom part with a trough for containing the bicarbonate, a cover for closing the trough and a two-channel plug-in connector for connection to a dialysis apparatus, the bottom part and the top part include flanges which are joined and form therebetween a conduit channel extending from one end of the container where the plug-in connector is disposed to the other end of the container for conducting liquid supplied through one of the plug-in connector channels through the bicarbonate filling of the trough of the container in which the bicarbonate is disposed to the other channel of the plug-in connector.